BG63339B1 - Бензопирани и тяхното приложение като терапевтични вещества - Google Patents
Бензопирани и тяхното приложение като терапевтични вещества Download PDFInfo
- Publication number
- BG63339B1 BG63339B1 BG101040A BG10104096A BG63339B1 BG 63339 B1 BG63339 B1 BG 63339B1 BG 101040 A BG101040 A BG 101040A BG 10104096 A BG10104096 A BG 10104096A BG 63339 B1 BG63339 B1 BG 63339B1
- Authority
- BG
- Bulgaria
- Prior art keywords
- acetyl
- dihydro
- dimethyl
- benzopyran
- trans
- Prior art date
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Classifications
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9411632A GB9411632D0 (en) | 1994-06-10 | 1994-06-10 | Novel treatment |
| GB9411798A GB9411798D0 (en) | 1994-06-13 | 1994-06-13 | Novel treatment |
| PCT/EP1995/002076 WO1995034545A1 (en) | 1994-06-10 | 1995-05-31 | Benzopyrans and their use as therapeutic agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BG101040A BG101040A (en) | 1997-08-29 |
| BG63339B1 true BG63339B1 (bg) | 2001-10-31 |
Family
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Family Applications (1)
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| BG101040A BG63339B1 (bg) | 1994-06-10 | 1996-12-10 | Бензопирани и тяхното приложение като терапевтични вещества |
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| EP (2) | EP0764157B1 (cs) |
| JP (2) | JP3575767B2 (cs) |
| KR (1) | KR100397721B1 (cs) |
| CN (2) | CN1234702C (cs) |
| AP (1) | AP714A (cs) |
| AT (2) | ATE211469T1 (cs) |
| AU (1) | AU701060B2 (cs) |
| BG (1) | BG63339B1 (cs) |
| BR (1) | BR9507980A (cs) |
| CA (1) | CA2192480C (cs) |
| CY (1) | CY2508B1 (cs) |
| CZ (1) | CZ286081B6 (cs) |
| DE (2) | DE69531801T2 (cs) |
| DK (2) | DK0764157T3 (cs) |
| ES (2) | ES2170798T3 (cs) |
| FI (1) | FI120686B (cs) |
| HK (1) | HK1039115B (cs) |
| HU (1) | HUT76136A (cs) |
| NO (1) | NO315651B1 (cs) |
| NZ (1) | NZ287872A (cs) |
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| PL (1) | PL188134B1 (cs) |
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| RO (1) | RO113463B1 (cs) |
| SG (1) | SG67930A1 (cs) |
| SI (2) | SI0764157T1 (cs) |
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| WO (1) | WO1995034545A1 (cs) |
Families Citing this family (16)
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| US20010021780A1 (en) * | 1992-12-11 | 2001-09-13 | Smithkline Beecham P.L.C. | Pharmaceutical composition containing bicyclic type compounds |
| GB9411635D0 (en) * | 1994-06-10 | 1994-08-03 | Smithkline Beecham Plc | Novel treatment |
| US6492415B2 (en) * | 1996-09-18 | 2002-12-10 | Smithkline Beecham P.L.C. | Use of benzopyranols to treat neurological disorders |
| GB9619492D0 (en) * | 1996-09-18 | 1996-10-30 | Smithkline Beecham Plc | Novel treatment |
| GB9726543D0 (en) * | 1997-12-16 | 1998-02-11 | Smithkline Beecham Plc | Novel compositions |
| GB9813949D0 (en) * | 1998-06-29 | 1998-08-26 | Smithkline Beecham Plc | Novel compounds |
| GB0028697D0 (en) * | 2000-11-23 | 2001-01-10 | S P A | Novel process |
| MY142214A (en) * | 2005-04-04 | 2010-11-15 | Takeda Pharmaceutical | Prophylactic or therapeutic agent for depression or anxiety disorder |
| MX2010013312A (es) * | 2008-06-05 | 2011-05-30 | Minster Res Ltd | Tratamientos novedoos. |
| CA2726878A1 (en) * | 2008-06-05 | 2009-12-10 | Minster Research Limited | Novel treatments |
| CA2782631A1 (en) | 2009-12-03 | 2011-06-09 | Proximagen Ltd | Treatment of infectious diseases |
| CN102970991A (zh) * | 2009-12-03 | 2013-03-13 | 普罗克西梅根有限公司 | 异常性疼痛和痛觉增敏的治疗 |
| AU2013285164A1 (en) | 2012-07-03 | 2015-01-22 | Proximagen Limited | Pro-drug compounds |
| GB201304814D0 (en) * | 2013-03-15 | 2013-05-01 | Proximagen Ltd | Pro-drug compounds |
| GB201322932D0 (en) * | 2013-12-23 | 2014-02-12 | Proximagen Ltd | Pro-drug compounds |
| GB201322934D0 (en) | 2013-12-23 | 2014-02-12 | Proximagen Ltd | Prodrug compounds |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3479726D1 (de) * | 1983-05-18 | 1989-10-19 | Beecham Group Plc | Benzopyran derivatives. |
| GB9112721D0 (en) * | 1991-06-13 | 1991-07-31 | Smithkline Beecham Plc | Novel treatment |
| WO1994013657A1 (en) * | 1992-12-11 | 1994-06-23 | Smithkline Beecham Plc | Pharmaceutical composition containing bicyclic type compounds |
| AU679475B2 (en) * | 1992-12-11 | 1997-07-03 | Smithkline Beecham Corporation | Bicyclic compounds with pharmaceutical activity |
| US5536718A (en) * | 1995-01-17 | 1996-07-16 | American Cyanamid Company | Tricyclic benzazepine vasopressin antagonists |
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1995
- 1995-05-31 DK DK95921798T patent/DK0764157T3/da active
- 1995-05-31 CA CA002192480A patent/CA2192480C/en not_active Expired - Lifetime
- 1995-05-31 AU AU26727/95A patent/AU701060B2/en not_active Expired
- 1995-05-31 AT AT95921798T patent/ATE211469T1/de active
- 1995-05-31 BR BR9507980A patent/BR9507980A/pt not_active IP Right Cessation
- 1995-05-31 SK SK1587-96A patent/SK281456B6/sk not_active IP Right Cessation
- 1995-05-31 DK DK01200801T patent/DK1114821T3/da active
- 1995-05-31 PT PT01200801T patent/PT1114821E/pt unknown
- 1995-05-31 CZ CZ19963617A patent/CZ286081B6/cs not_active IP Right Cessation
- 1995-05-31 JP JP50155696A patent/JP3575767B2/ja not_active Expired - Lifetime
- 1995-05-31 CN CNB01124366XA patent/CN1234702C/zh not_active Expired - Lifetime
- 1995-05-31 PL PL95317579A patent/PL188134B1/pl unknown
- 1995-05-31 HU HU9603415A patent/HUT76136A/hu not_active Application Discontinuation
- 1995-05-31 EP EP95921798A patent/EP0764157B1/en not_active Expired - Lifetime
- 1995-05-31 SG SG1996008495A patent/SG67930A1/en unknown
- 1995-05-31 RO RO96-02326A patent/RO113463B1/ro unknown
- 1995-05-31 NZ NZ287872A patent/NZ287872A/en not_active IP Right Cessation
- 1995-05-31 DE DE69531801T patent/DE69531801T2/de not_active Expired - Lifetime
- 1995-05-31 PT PT95921798T patent/PT764157E/pt unknown
- 1995-05-31 AT AT01200801T patent/ATE250052T1/de active
- 1995-05-31 DE DE69524871T patent/DE69524871T2/de not_active Expired - Lifetime
- 1995-05-31 EP EP01200801A patent/EP1114821B1/en not_active Expired - Lifetime
- 1995-05-31 WO PCT/EP1995/002076 patent/WO1995034545A1/en not_active Ceased
- 1995-05-31 AP APAP/P/1996/000889A patent/AP714A/en active
- 1995-05-31 CN CNB951944134A patent/CN1174975C/zh not_active Expired - Lifetime
- 1995-05-31 ES ES95921798T patent/ES2170798T3/es not_active Expired - Lifetime
- 1995-05-31 SI SI9530579T patent/SI0764157T1/xx unknown
- 1995-05-31 ES ES01200801T patent/ES2207590T3/es not_active Expired - Lifetime
- 1995-05-31 SI SI9530691T patent/SI1114821T1/xx unknown
- 1995-05-31 KR KR1019960707048A patent/KR100397721B1/ko not_active Expired - Lifetime
- 1995-06-02 US US08/460,151 patent/US5760074A/en not_active Expired - Lifetime
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1996
- 1996-12-09 NO NO19965260A patent/NO315651B1/no not_active IP Right Cessation
- 1996-12-10 FI FI964936A patent/FI120686B/fi not_active IP Right Cessation
- 1996-12-10 BG BG101040A patent/BG63339B1/bg unknown
- 1996-12-10 OA OA60933A patent/OA10593A/en unknown
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2002
- 2002-01-10 HK HK02100192.4A patent/HK1039115B/en not_active IP Right Cessation
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2003
- 2003-01-23 JP JP2003014984A patent/JP2003238554A/ja active Pending
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2005
- 2005-03-15 CY CY0500017A patent/CY2508B1/xx unknown
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