BG63338B1 - Кристални производни на n-ацетил невраминова киселина и методи за тяхното получаване - Google Patents
Кристални производни на n-ацетил невраминова киселина и методи за тяхното получаване Download PDFInfo
- Publication number
- BG63338B1 BG63338B1 BG100709A BG10070996A BG63338B1 BG 63338 B1 BG63338 B1 BG 63338B1 BG 100709 A BG100709 A BG 100709A BG 10070996 A BG10070996 A BG 10070996A BG 63338 B1 BG63338 B1 BG 63338B1
- Authority
- BG
- Bulgaria
- Prior art keywords
- crystalline form
- hydrate
- guanidino
- tetradeoxy
- aqueous solution
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Oncology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB939325841A GB9325841D0 (en) | 1993-12-17 | 1993-12-17 | Chemical compounds |
PCT/EP1994/004154 WO1995016680A1 (en) | 1993-12-17 | 1994-12-15 | Crystalline n-acetyl neuraminic acid derivatives and processes for their preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
BG100709A BG100709A (bg) | 1997-01-31 |
BG63338B1 true BG63338B1 (bg) | 2001-10-31 |
Family
ID=10746778
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG100709A BG63338B1 (bg) | 1993-12-17 | 1996-07-08 | Кристални производни на n-ацетил невраминова киселина и методи за тяхното получаване |
Country Status (44)
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9325841D0 (en) * | 1993-12-17 | 1994-02-23 | Glaxo Group Ltd | Chemical compounds |
US5866601A (en) * | 1995-02-27 | 1999-02-02 | Gilead Sciences, Inc. | Carbocyclic compounds |
HU228450B1 (en) | 1995-02-27 | 2013-03-28 | Gilead Sciences Inc | Novel selective inhibitors of viral or bacterial neuraminidases |
US5763483A (en) * | 1995-12-29 | 1998-06-09 | Gilead Sciences, Inc. | Carbocyclic compounds |
EP0823428B1 (en) * | 1996-07-22 | 2002-01-02 | Sankyo Company Limited | Neuraminic acid derivatives, their preparation and their medical use |
US6340702B1 (en) | 1996-07-22 | 2002-01-22 | Sankyo Company, Limited | Neuraminic acid derivatives, their preparation and their medical use |
US6451766B1 (en) | 1996-07-22 | 2002-09-17 | Sankyo Company, Limited | Neuraminic acid derivatives, their preparation and their medical use |
US5859284A (en) * | 1996-08-23 | 1999-01-12 | Gilead Sciences, Inc. | Preparation of carbocyclic compounds |
US6518438B2 (en) | 1996-08-23 | 2003-02-11 | Gilead Sciences, Inc. | Preparation of cyclohexene carboxylate derivatives |
US5994377A (en) * | 1996-10-21 | 1999-11-30 | Gilead Sciences, Inc. | Piperidine compounds |
US5886213A (en) * | 1997-08-22 | 1999-03-23 | Gilead Sciences, Inc. | Preparation of carbocyclic compounds |
TW477783B (en) * | 1997-12-12 | 2002-03-01 | Gilead Sciences Inc | Novel compounds useful as neuraminidase inhibitors and pharmaceutical compositions containing same |
TWI291462B (en) | 2000-04-25 | 2007-12-21 | Daiichi Sankyo Co Ltd | Hydrate crystal of neuraminic acid compound |
US20080063722A1 (en) * | 2006-09-08 | 2008-03-13 | Advanced Inhalation Research, Inc. | Composition of a Spray-Dried Powder for Pulmonary Delivery of a Long Acting Neuraminidase Inhibitor (LANI) |
EP2792676A4 (en) * | 2011-12-16 | 2015-10-07 | Daiichi Sankyo Co Ltd | PROCESS FOR PREPARING NEURAMINE ACID DERIVATIVES |
CN109232677B (zh) * | 2018-10-18 | 2021-12-28 | 中国科学院合肥物质科学研究院 | 一种使n-乙酰神经氨酸水合物转化为n-乙酰神经氨酸的方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AP249A (en) * | 1990-04-24 | 1993-03-17 | Biota Scient Management Pty Ltd | Anti-viral compounds. |
AU659501B2 (en) * | 1991-10-23 | 1995-05-18 | Biota Scientific Management Pty Ltd | Antiviral 4-substituted-2-deoxy-2,3-didehydro-derivatives of alpha-D-neuraminic acid |
US5639786A (en) | 1992-12-04 | 1997-06-17 | Biota Scientific Management, Pty., Ltd. | Antiviral 4-substituted-2-deoxy-2,3-didehydro-derivatives of α-D-neuraninic acid |
GB9325841D0 (en) * | 1993-12-17 | 1994-02-23 | Glaxo Group Ltd | Chemical compounds |
-
1993
- 1993-12-17 GB GB939325841A patent/GB9325841D0/en active Pending
-
1994
- 1994-12-02 TW TW083111229A patent/TW452577B/zh not_active IP Right Cessation
- 1994-12-13 IS IS4240A patent/IS4240A/is unknown
- 1994-12-15 UA UA96062328A patent/UA46723C2/uk unknown
- 1994-12-15 KR KR1019960703180A patent/KR100403256B1/ko not_active IP Right Cessation
- 1994-12-15 CZ CZ19961693A patent/CZ289234B6/cs not_active IP Right Cessation
- 1994-12-15 SI SI9430333T patent/SI0734382T1/xx unknown
- 1994-12-15 DE DE69426726T patent/DE69426726T2/de not_active Expired - Lifetime
- 1994-12-15 AP APAP/P/1996/000810A patent/AP9600810A0/en unknown
- 1994-12-15 HU HU9601642A patent/HU221971B1/hu active IP Right Grant
- 1994-12-15 EG EG79094A patent/EG20597A/xx active
- 1994-12-15 JP JP51653195A patent/JP3317972B2/ja not_active Expired - Lifetime
- 1994-12-15 ZA ZA9410003A patent/ZA9410003B/xx unknown
- 1994-12-15 HR HR941001A patent/HRP941001B1/xx not_active IP Right Cessation
- 1994-12-15 CN CNA2003101199989A patent/CN1502621A/zh active Pending
- 1994-12-15 MY MYPI94003357A patent/MY116221A/en unknown
- 1994-12-15 PE PE1994257245A patent/PE31095A1/es not_active Application Discontinuation
- 1994-12-15 EE EE9600135A patent/EE03353B1/xx unknown
- 1994-12-15 CA CA002177990A patent/CA2177990C/en not_active Expired - Lifetime
- 1994-12-15 RU RU96115122A patent/RU2134690C1/ru active Protection Beyond IP Right Term
- 1994-12-15 CO CO94056728A patent/CO4340619A1/es unknown
- 1994-12-15 EP EP95904472A patent/EP0734382B1/en not_active Expired - Lifetime
- 1994-12-15 WO PCT/EP1994/004154 patent/WO1995016680A1/en active IP Right Grant
- 1994-12-15 RO RO96-01195A patent/RO114792B1/ro unknown
- 1994-12-15 SK SK785-96A patent/SK282972B6/sk not_active IP Right Cessation
- 1994-12-15 AT AT95904472T patent/ATE199255T1/de active
- 1994-12-15 DK DK95904472T patent/DK0734382T3/da active
- 1994-12-15 PL PL94315055A patent/PL186384B1/pl unknown
- 1994-12-15 BR BR9408340A patent/BR9408340A/pt not_active Application Discontinuation
- 1994-12-15 AP APAP/P/1994/000705A patent/AP541A/en active
- 1994-12-15 CN CN94194973A patent/CN1132829C/zh not_active Expired - Lifetime
- 1994-12-15 PT PT95904472T patent/PT734382E/pt unknown
- 1994-12-15 SV SV1994000076A patent/SV1994000076A/es active IP Right Grant
- 1994-12-15 MA MA23724A patent/MA23396A1/fr unknown
- 1994-12-15 NZ NZ277789A patent/NZ277789A/en not_active IP Right Cessation
- 1994-12-15 SG SG1996007725A patent/SG46669A1/en unknown
- 1994-12-15 ES ES95904472T patent/ES2155517T3/es not_active Expired - Lifetime
- 1994-12-16 IL IL11201194A patent/IL112011A/en not_active IP Right Cessation
- 1994-12-28 SA SA94150417A patent/SA94150417B1/ar unknown
-
1996
- 1996-06-13 FI FI962464A patent/FI120453B/fi not_active IP Right Cessation
- 1996-06-14 OA OA60842A patent/OA10325A/fr unknown
- 1996-06-14 NO NO19962545A patent/NO314759B1/no not_active IP Right Cessation
- 1996-07-08 BG BG100709A patent/BG63338B1/bg unknown
-
1997
- 1997-05-13 BR BRPP1100548-KB1A patent/BR1100548KB1/pt unknown
-
1998
- 1998-12-24 HK HK98115499A patent/HK1014187A1/xx not_active IP Right Cessation
-
1999
- 1999-07-02 US US09/346,583 patent/US6294572B1/en not_active Expired - Lifetime
-
2000
- 2000-01-06 OA OA1200000004A patent/OA11275A/fr unknown
-
2001
- 2001-03-30 GR GR20010400531T patent/GR3035681T3/el unknown
- 2001-09-24 US US09/961,074 patent/US20020037865A1/en not_active Abandoned
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