BG62954B1 - Екстракт от акулов хрущял с анти-ангиогенна активност и въздействието му за туморна регресия: метод за неговото получаване - Google Patents

Екстракт от акулов хрущял с анти-ангиогенна активност и въздействието му за туморна регресия: метод за неговото получаване Download PDF

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Publication number
BG62954B1
BG62954B1 BG100941A BG10094196A BG62954B1 BG 62954 B1 BG62954 B1 BG 62954B1 BG 100941 A BG100941 A BG 100941A BG 10094196 A BG10094196 A BG 10094196A BG 62954 B1 BG62954 B1 BG 62954B1
Authority
BG
Bulgaria
Prior art keywords
cartilage
kda
extract
liquid
molecular weight
Prior art date
Application number
BG100941A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG100941A (en
Inventor
Eric Dupont
Paul Brazeau
Christian Juneau
Original Assignee
Les Laboratoires Aeterna Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Les Laboratoires Aeterna Inc. filed Critical Les Laboratoires Aeterna Inc.
Publication of BG100941A publication Critical patent/BG100941A/xx
Publication of BG62954B1 publication Critical patent/BG62954B1/bg

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/60—Fish, e.g. seahorses; Fish eggs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BG100941A 1994-04-28 1996-10-28 Екстракт от акулов хрущял с анти-ангиогенна активност и въздействието му за туморна регресия: метод за неговото получаване BG62954B1 (bg)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23401994A 1994-04-28 1994-04-28
US08/384,555 US5618925A (en) 1994-04-28 1995-02-03 Extracts of shark cartilage having an anti-angiogenic activity and an effect on tumor regression; process of making thereof
PCT/CA1995/000233 WO1995032722A1 (en) 1994-04-28 1995-04-21 Extracts of shark cartilage having an anti-angiogenic activity and an effect on tumor regression; process of making thereof

Publications (2)

Publication Number Publication Date
BG100941A BG100941A (en) 1997-07-31
BG62954B1 true BG62954B1 (bg) 2000-12-29

Family

ID=26927471

Family Applications (1)

Application Number Title Priority Date Filing Date
BG100941A BG62954B1 (bg) 1994-04-28 1996-10-28 Екстракт от акулов хрущял с анти-ангиогенна активност и въздействието му за туморна регресия: метод за неговото получаване

Country Status (24)

Country Link
US (2) US5618925A (es)
EP (1) EP0759765B1 (es)
JP (1) JPH09512563A (es)
KR (1) KR100378787B1 (es)
CN (2) CN1147305C (es)
AT (1) ATE224198T1 (es)
BG (1) BG62954B1 (es)
BR (1) BR9507552A (es)
CA (1) CA2188793C (es)
CZ (1) CZ290520B6 (es)
DE (1) DE69528258T2 (es)
DK (1) DK0759765T3 (es)
ES (1) ES2182900T3 (es)
FI (1) FI117375B (es)
HU (1) HU220784B1 (es)
IS (1) IS1975B (es)
NO (1) NO317674B1 (es)
NZ (1) NZ284407A (es)
PL (1) PL181981B1 (es)
PT (1) PT759765E (es)
RO (1) RO114868B1 (es)
RU (1) RU2156132C2 (es)
SI (1) SI0759765T1 (es)
WO (1) WO1995032722A1 (es)

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US6028118A (en) * 1996-08-08 2000-02-22 Les Laboratoires Aeterna Inc. Methods of using extracts of shark cartilage
US6025334A (en) * 1994-04-28 2000-02-15 Les Laboratoires Aeterna Inc. Extracts of shark cartilage having anti-collagenolytic, anti-inflammatory, anti-angiogenic and anti-tumoral activities; process of making, methods of using and compositions thereof
US5618925A (en) * 1994-04-28 1997-04-08 Les Laboratories Aeterna Inc. Extracts of shark cartilage having an anti-angiogenic activity and an effect on tumor regression; process of making thereof
DE69529300T2 (de) * 1995-02-03 2003-07-03 Aeterna Lab Inc Haiknorpel extrakte,verfahren zur herstellung und verwendungen desselben
US5843920A (en) * 1996-09-16 1998-12-01 Biocell Technology, Llc Anionic saccharides for extraction of anti-angiogenic protein from cartilage
CA2288269A1 (en) * 1997-02-20 1998-08-27 Industrial Research Limited Angiogenesis inhibitors and activators from shark cartilage
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KR100732322B1 (ko) * 1997-07-11 2007-06-25 에프엑스 라이프 싸이언스즈 인터내셔널 게엠베하 피에이취에프 과다 또는 세포내 칼슘 과다와 관련한질병을 치료하기 위한 상어 연골에서 유래한 조제물
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DK1520588T3 (en) 1998-07-13 2015-03-23 Univ Texas Use of antibodies to aminophospholipids for cancer treatment
US6168807B1 (en) 1998-07-23 2001-01-02 Les Laboratoires Aeterna Inc. Low molecular weight components of shark cartilage, processes for their preparation and therapeutic uses thereof
US20020009501A1 (en) * 1998-07-23 2002-01-24 Eric Dupont Preparation of cartilage extracts using organic solvents
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AUPR222300A0 (en) * 2000-12-21 2001-01-25 Life Therapeutics Limited Electrophoresis device and method
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US20030087830A1 (en) * 2001-06-12 2003-05-08 Eric Dupont Low molecular weight components of cartilage, complexes of metals with amino acids, DI-peptides and analogs thereof; processes for preparation and therapeutic uses thereof
US6908627B2 (en) * 2001-06-21 2005-06-21 Mote Marine Laboratory Conditioned media for inhibiting growth of tumor cells
US7309501B2 (en) * 2001-06-21 2007-12-18 Mote Marine Laboratory Conditioned media to inhibit growth of tumor cells
AU2002233088A1 (en) 2002-02-15 2003-09-04 Ocean Nutrition Canada Limited Shark cartilage extracts and use thereof for immunomodulation
MX337052B (es) 2002-07-15 2016-02-11 Univ Texas Peptidos que se enlazan a fosfatidiletanolamina y sus usos en el tratamiento de infecciones virales y del cancer.
JPWO2004083257A1 (ja) * 2003-03-20 2006-06-22 ホソカワミクロン株式会社 軟骨魚類から単離されたプロテオグリカンおよびその製造方法
US7067123B2 (en) 2003-04-29 2006-06-27 Musculoskeletal Transplant Foundation Glue for cartilage repair
US7901457B2 (en) * 2003-05-16 2011-03-08 Musculoskeletal Transplant Foundation Cartilage allograft plug
ES2223291B1 (es) * 2003-08-06 2006-03-16 Bioiberica, S.A. Nuevo uso terapeutico de condroitin sulfato.
WO2005058207A1 (en) 2003-12-11 2005-06-30 Isto Technologies, Inc. Particulate cartilage system
MXPA06008293A (es) 2004-01-22 2007-06-11 Univ Miami Formulaciones topicas de coenzima q10 y metodos de uso.
CN100377741C (zh) * 2004-02-23 2008-04-02 江卫世 注射用复方骨肽及其制备工艺
US20050288796A1 (en) * 2004-06-23 2005-12-29 Hani Awad Native soft tissue matrix for therapeutic applications
US7837740B2 (en) * 2007-01-24 2010-11-23 Musculoskeletal Transplant Foundation Two piece cancellous construct for cartilage repair
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US8163549B2 (en) 2006-12-20 2012-04-24 Zimmer Orthobiologics, Inc. Method of obtaining viable small tissue particles and use for tissue repair
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WO2012099216A1 (ja) * 2011-01-19 2012-07-26 国立大学法人弘前大学 プロテオグリカンの大量調製法
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CN104894200B (zh) * 2015-05-12 2020-10-30 浙江海洋学院 路氏双髻鲨软骨血管生成抑制因子的制备方法
KR101628982B1 (ko) 2015-11-27 2016-06-09 김준혁 항종양 및 면역 증강용 건강식품 조성물
EP3576726A1 (en) 2017-02-06 2019-12-11 Massachusetts Institute Of Technology Methods and products related to glutaminase inhibitors
CN109394786A (zh) * 2018-10-26 2019-03-01 西交利物浦大学 一种抗肿瘤的药物组合物
WO2020203812A1 (ja) * 2019-03-29 2020-10-08 学校法人慶應義塾 魚介類由来成分による低酸素応答制御
WO2020251412A2 (ru) * 2019-06-14 2020-12-17 Общество С Ограниченной Ответственностью "Айтупайф" (Ооо "Айтулайф") Способ получения йодированных белков с детерминированным содержанием йода
CN112986499A (zh) * 2021-02-26 2021-06-18 山西奥瑞生物材料有限公司 一种同种骨植入材料残余水量均匀度测定方法

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Also Published As

Publication number Publication date
IS4379A (is) 1996-10-25
AU719118B2 (en) 2000-05-04
KR970702729A (ko) 1997-06-10
ES2182900T3 (es) 2003-03-16
BR9507552A (pt) 1997-08-05
NO964547D0 (no) 1996-10-25
DE69528258T2 (de) 2003-04-17
CZ290520B6 (cs) 2002-08-14
NO964547L (no) 1996-12-30
PL317076A1 (en) 1997-03-03
HU9602975D0 (en) 1997-01-28
US5618925A (en) 1997-04-08
RO114868B1 (ro) 1999-08-30
PT759765E (pt) 2003-02-28
CN1147305C (zh) 2004-04-28
PL181981B1 (en) 2001-10-31
BG100941A (en) 1997-07-31
AU2300195A (en) 1995-12-21
ATE224198T1 (de) 2002-10-15
KR100378787B1 (ko) 2003-06-19
NO317674B1 (no) 2004-11-29
EP0759765B1 (en) 2002-09-18
FI964327A0 (fi) 1996-10-28
US5985839A (en) 1999-11-16
CA2188793A1 (en) 1995-12-07
IS1975B (is) 2005-01-14
HUT76554A (en) 1997-09-29
CN1153477A (zh) 1997-07-02
DK0759765T3 (da) 2003-01-27
HU220784B1 (hu) 2002-05-28
DE69528258D1 (de) 2002-10-24
JPH09512563A (ja) 1997-12-16
RU2156132C2 (ru) 2000-09-20
SI0759765T1 (en) 2003-02-28
FI964327A (fi) 1996-12-20
CZ314196A3 (en) 1997-04-16
NZ284407A (en) 1998-04-27
CA2188793C (en) 2001-01-16
WO1995032722A1 (en) 1995-12-07
EP0759765A1 (en) 1997-03-05
FI117375B (fi) 2006-09-29
CN1541656A (zh) 2004-11-03

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