BG62596B1 - Инхибитори на ротамазна ензимна активност - Google Patents
Инхибитори на ротамазна ензимна активност Download PDFInfo
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/551,026 US20020013344A1 (en) | 1995-10-31 | 1995-10-31 | Rotamas enzyme activity inhibitors |
| US08/645,149 US5801197A (en) | 1995-10-31 | 1996-05-13 | Rotamase enzyme activity inhibitors |
| PCT/US1996/013624 WO1997016190A1 (fr) | 1995-10-31 | 1996-08-26 | Inhibiteurs de l'activite de l'enzyme rotamase |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BG102410A BG102410A (en) | 1998-12-30 |
| BG62596B1 true BG62596B1 (bg) | 2000-03-31 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG102410A BG62596B1 (bg) | 1995-10-31 | 1998-04-28 | Инхибитори на ротамазна ензимна активност |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5801197A (fr) |
| EP (1) | EP0859614A4 (fr) |
| JP (1) | JPH11514643A (fr) |
| KR (1) | KR19990067257A (fr) |
| BG (1) | BG62596B1 (fr) |
| BR (1) | BRPI9611271A2 (fr) |
| CA (1) | CA2236328A1 (fr) |
| CZ (1) | CZ125198A3 (fr) |
| EA (1) | EA001481B1 (fr) |
| EE (1) | EE9800125A (fr) |
| HU (1) | HUP9901752A3 (fr) |
| LV (1) | LV12102B (fr) |
| NO (1) | NO981903L (fr) |
| NZ (1) | NZ316361A (fr) |
| PL (1) | PL326420A1 (fr) |
| SK (1) | SK55998A3 (fr) |
| WO (1) | WO1997016190A1 (fr) |
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| US5744485A (en) * | 1994-03-25 | 1998-04-28 | Vertex Pharmaceuticals Incorporated | Carbamates and ureas as modifiers of multi-drug resistance |
| US5856116A (en) * | 1994-06-17 | 1999-01-05 | Vertex Pharmaceuticals, Incorporated | Crystal structure and mutants of interleukin-1 beta converting enzyme |
| US5716929A (en) * | 1994-06-17 | 1998-02-10 | Vertex Pharmaceuticals, Inc. | Inhibitors of interleukin-1β converting enzyme |
| CA2197793C (fr) * | 1994-08-18 | 2007-04-24 | Dennis A. Holt | Nouveaux agents de multimerisation |
| IL115685A (en) * | 1994-11-16 | 2000-08-31 | Vertex Pharma | Amino acid derivatives pharmaceutical compositions containing the same and processes for the preparation thereof |
| US5543423A (en) * | 1994-11-16 | 1996-08-06 | Vertex Pharmaceuticals, Incorporated | Amino acid derivatives with improved multi-drug resistance activity |
| US5621108A (en) * | 1994-12-05 | 1997-04-15 | Trustees Of The University Of Pennsylvania | Processes and intermediates for preparing macrocycles |
| US5859031A (en) * | 1995-06-07 | 1999-01-12 | Gpi Nil Holdings, Inc. | Small molecule inhibitors of rotamase enzyme activity |
| US5696135A (en) * | 1995-06-07 | 1997-12-09 | Gpi Nil Holdings, Inc. | Inhibitors of rotamase enzyme activity effective at stimulating neuronal growth |
| US6037370A (en) * | 1995-06-08 | 2000-03-14 | Vertex Pharmaceuticals Incorporated | Methods and compositions for stimulating neurite growth |
-
1996
- 1996-05-13 US US08/645,149 patent/US5801197A/en not_active Expired - Lifetime
- 1996-08-26 SK SK559-98A patent/SK55998A3/sk unknown
- 1996-08-26 EA EA199800329A patent/EA001481B1/ru not_active IP Right Cessation
- 1996-08-26 NZ NZ316361A patent/NZ316361A/xx unknown
- 1996-08-26 EP EP96929014A patent/EP0859614A4/fr not_active Withdrawn
- 1996-08-26 PL PL96326420A patent/PL326420A1/xx unknown
- 1996-08-26 KR KR1019980703218A patent/KR19990067257A/ko not_active Application Discontinuation
- 1996-08-26 HU HU9901752A patent/HUP9901752A3/hu unknown
- 1996-08-26 WO PCT/US1996/013624 patent/WO1997016190A1/fr not_active Application Discontinuation
- 1996-08-26 BR BRPI9611271-9A patent/BRPI9611271A2/pt unknown
- 1996-08-26 CZ CZ981251A patent/CZ125198A3/cs unknown
- 1996-08-26 CA CA002236328A patent/CA2236328A1/fr not_active Abandoned
- 1996-08-26 EE EE9800125A patent/EE9800125A/xx unknown
- 1996-08-26 JP JP9517308A patent/JPH11514643A/ja active Pending
-
1998
- 1998-04-27 NO NO981903A patent/NO981903L/no not_active Application Discontinuation
- 1998-04-28 BG BG102410A patent/BG62596B1/bg unknown
- 1998-06-25 LV LVP-98-85A patent/LV12102B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NZ316361A (en) | 1999-08-30 |
| EA001481B1 (ru) | 2001-04-23 |
| LV12102B (en) | 1998-10-20 |
| US5801197A (en) | 1998-09-01 |
| LV12102A (lv) | 1998-08-20 |
| BRPI9611271A2 (pt) | 2019-04-30 |
| HUP9901752A3 (en) | 2001-04-28 |
| CZ125198A3 (cs) | 1998-12-16 |
| JPH11514643A (ja) | 1999-12-14 |
| EP0859614A1 (fr) | 1998-08-26 |
| SK55998A3 (en) | 1999-02-11 |
| EA199800329A1 (ru) | 1998-12-24 |
| EE9800125A (et) | 1998-10-15 |
| WO1997016190A1 (fr) | 1997-05-09 |
| BG102410A (en) | 1998-12-30 |
| AU713302B2 (en) | 1999-11-25 |
| MX9803356A (es) | 1998-09-30 |
| AU6857396A (en) | 1997-05-22 |
| NO981903D0 (no) | 1998-04-27 |
| EP0859614A4 (fr) | 2000-04-26 |
| CA2236328A1 (fr) | 1997-05-09 |
| HUP9901752A2 (hu) | 1999-10-28 |
| KR19990067257A (ko) | 1999-08-16 |
| PL326420A1 (en) | 1998-09-14 |
| NO981903L (no) | 1998-06-30 |
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