BG62596B1 - Инхибитори на ротамазна ензимна активност - Google Patents
Инхибитори на ротамазна ензимна активност Download PDFInfo
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- KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 description 1
- 239000000829 suppository Substances 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 229940095064 tartrate Drugs 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 210000000115 thoracic cavity Anatomy 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 206010044652 trigeminal neuralgia Diseases 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Hydrogenated Pyridines (AREA)
- Peptides Or Proteins (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/551,026 US20020013344A1 (en) | 1995-10-31 | 1995-10-31 | Rotamas enzyme activity inhibitors |
| US08/645,149 US5801197A (en) | 1995-10-31 | 1996-05-13 | Rotamase enzyme activity inhibitors |
| PCT/US1996/013624 WO1997016190A1 (fr) | 1995-10-31 | 1996-08-26 | Inhibiteurs de l'activite de l'enzyme rotamase |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BG102410A BG102410A (en) | 1998-12-30 |
| BG62596B1 true BG62596B1 (bg) | 2000-03-31 |
Family
ID=27069634
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG102410A BG62596B1 (bg) | 1995-10-31 | 1998-04-28 | Инхибитори на ротамазна ензимна активност |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5801197A (fr) |
| EP (1) | EP0859614A4 (fr) |
| JP (1) | JPH11514643A (fr) |
| KR (1) | KR19990067257A (fr) |
| BG (1) | BG62596B1 (fr) |
| BR (1) | BRPI9611271A2 (fr) |
| CA (1) | CA2236328A1 (fr) |
| CZ (1) | CZ125198A3 (fr) |
| EA (1) | EA001481B1 (fr) |
| EE (1) | EE9800125A (fr) |
| HU (1) | HUP9901752A3 (fr) |
| LV (1) | LV12102B (fr) |
| NO (1) | NO981903L (fr) |
| NZ (1) | NZ316361A (fr) |
| PL (1) | PL326420A1 (fr) |
| SK (1) | SK55998A3 (fr) |
| WO (1) | WO1997016190A1 (fr) |
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| US5859031A (en) * | 1995-06-07 | 1999-01-12 | Gpi Nil Holdings, Inc. | Small molecule inhibitors of rotamase enzyme activity |
| AT500193B1 (de) * | 1995-06-07 | 2007-11-15 | Guilford Pharm Inc | Neurotrophe verbindung und verfahren zu ihrer herstellung |
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| EA002401B1 (ru) * | 1996-12-31 | 2002-04-25 | Джи Пи Ай Нил Холдингс, Инк. | N-связанные мочевины и карбаматы сложных гетероциклических тиоэфиров |
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| US20010049381A1 (en) * | 1997-06-04 | 2001-12-06 | Gpl Nil Holdings, Inc., | Pyrrolidine derivative hair growth compositions and uses |
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| IT1270882B (it) * | 1993-10-05 | 1997-05-13 | Isagro Srl | Oligopeptidi ad attivita' fungicida |
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| EP0749421B1 (fr) * | 1994-03-07 | 1999-09-15 | Vertex Pharmaceuticals Incorporated | Derives de sulfamides en tant qu'inhibiteurs de protease d'aspartyle |
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-
1996
- 1996-05-13 US US08/645,149 patent/US5801197A/en not_active Expired - Lifetime
- 1996-08-26 KR KR1019980703218A patent/KR19990067257A/ko not_active Application Discontinuation
- 1996-08-26 JP JP9517308A patent/JPH11514643A/ja active Pending
- 1996-08-26 EP EP96929014A patent/EP0859614A4/fr not_active Withdrawn
- 1996-08-26 CA CA002236328A patent/CA2236328A1/fr not_active Abandoned
- 1996-08-26 HU HU9901752A patent/HUP9901752A3/hu unknown
- 1996-08-26 NZ NZ316361A patent/NZ316361A/xx unknown
- 1996-08-26 CZ CZ981251A patent/CZ125198A3/cs unknown
- 1996-08-26 BR BRPI9611271-9A patent/BRPI9611271A2/pt unknown
- 1996-08-26 EE EE9800125A patent/EE9800125A/xx unknown
- 1996-08-26 WO PCT/US1996/013624 patent/WO1997016190A1/fr not_active Application Discontinuation
- 1996-08-26 EA EA199800329A patent/EA001481B1/ru not_active IP Right Cessation
- 1996-08-26 PL PL96326420A patent/PL326420A1/xx unknown
- 1996-08-26 SK SK559-98A patent/SK55998A3/sk unknown
-
1998
- 1998-04-27 NO NO981903A patent/NO981903L/no not_active Application Discontinuation
- 1998-04-28 BG BG102410A patent/BG62596B1/bg unknown
- 1998-06-25 LV LVP-98-85A patent/LV12102B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SK55998A3 (en) | 1999-02-11 |
| EA199800329A1 (ru) | 1998-12-24 |
| NO981903D0 (no) | 1998-04-27 |
| PL326420A1 (en) | 1998-09-14 |
| CA2236328A1 (fr) | 1997-05-09 |
| KR19990067257A (ko) | 1999-08-16 |
| JPH11514643A (ja) | 1999-12-14 |
| MX9803356A (es) | 1998-09-30 |
| LV12102B (en) | 1998-10-20 |
| HUP9901752A2 (hu) | 1999-10-28 |
| LV12102A (lv) | 1998-08-20 |
| BG102410A (en) | 1998-12-30 |
| NO981903L (no) | 1998-06-30 |
| US5801197A (en) | 1998-09-01 |
| EE9800125A (et) | 1998-10-15 |
| AU713302B2 (en) | 1999-11-25 |
| CZ125198A3 (cs) | 1998-12-16 |
| EA001481B1 (ru) | 2001-04-23 |
| EP0859614A1 (fr) | 1998-08-26 |
| NZ316361A (en) | 1999-08-30 |
| AU6857396A (en) | 1997-05-22 |
| EP0859614A4 (fr) | 2000-04-26 |
| BRPI9611271A2 (pt) | 2019-04-30 |
| WO1997016190A1 (fr) | 1997-05-09 |
| HUP9901752A3 (en) | 2001-04-28 |
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