MX9803356A - Inhibidores de la actividad de la enzima rotamasa. - Google Patents

Inhibidores de la actividad de la enzima rotamasa.

Info

Publication number
MX9803356A
MX9803356A MX9803356A MX9803356A MX9803356A MX 9803356 A MX9803356 A MX 9803356A MX 9803356 A MX9803356 A MX 9803356A MX 9803356 A MX9803356 A MX 9803356A MX 9803356 A MX9803356 A MX 9803356A
Authority
MX
Mexico
Prior art keywords
enzyme activity
inhibitors
activity inhibitors
rotamase enzyme
rotamase
Prior art date
Application number
MX9803356A
Other languages
English (en)
Other versions
MXPA98003356A (es
Inventor
Joseph P Steiner
Gregory S Hamilton
Original Assignee
Guilford Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/551,026 external-priority patent/US20020013344A1/en
Application filed by Guilford Pharm Inc filed Critical Guilford Pharm Inc
Publication of MX9803356A publication Critical patent/MX9803356A/es
Publication of MXPA98003356A publication Critical patent/MXPA98003356A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Abstract

Esta invencion se refiere al método de uso de compuestos derivados de ácido pipecolico neurotrofico formulados especialmente, que tienen una afinidad por inmunofilina tipo FKBP como inhibidores de la actividad de enzima asociada con proteínas inmunofilinas, y particularmente inhibidores de la actividad de la enzima peptidil-prolil isomerasa y rotamasa para estimular o promover el crecimiento o regeneracion neuronal.
MXPA/A/1998/003356A 1995-10-31 1998-04-28 Inhibidores de la actividad de la enzima rotamasa MXPA98003356A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US08/551,026 US20020013344A1 (en) 1995-10-31 1995-10-31 Rotamas enzyme activity inhibitors
US08551026 1995-10-31
US08645149 1996-05-13
US08/645,149 US5801197A (en) 1995-10-31 1996-05-13 Rotamase enzyme activity inhibitors

Publications (2)

Publication Number Publication Date
MX9803356A true MX9803356A (es) 1998-09-30
MXPA98003356A MXPA98003356A (es) 1998-11-16

Family

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Also Published As

Publication number Publication date
NZ316361A (en) 1999-08-30
EA001481B1 (ru) 2001-04-23
LV12102B (en) 1998-10-20
US5801197A (en) 1998-09-01
LV12102A (lv) 1998-08-20
BRPI9611271A2 (pt) 2019-04-30
HUP9901752A3 (en) 2001-04-28
CZ125198A3 (cs) 1998-12-16
JPH11514643A (ja) 1999-12-14
EP0859614A1 (en) 1998-08-26
SK55998A3 (en) 1999-02-11
EA199800329A1 (ru) 1998-12-24
BG62596B1 (bg) 2000-03-31
EE9800125A (et) 1998-10-15
WO1997016190A1 (en) 1997-05-09
BG102410A (en) 1998-12-30
AU713302B2 (en) 1999-11-25
AU6857396A (en) 1997-05-22
NO981903D0 (no) 1998-04-27
EP0859614A4 (en) 2000-04-26
CA2236328A1 (en) 1997-05-09
HUP9901752A2 (hu) 1999-10-28
KR19990067257A (ko) 1999-08-16
PL326420A1 (en) 1998-09-14
NO981903L (no) 1998-06-30

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