BG62492B1 - Състави и методи за идентифициране и синтез насиалилтрансферази - Google Patents

Състави и методи за идентифициране и синтез насиалилтрансферази Download PDF

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Publication number
BG62492B1
BG62492B1 BG99100A BG9910094A BG62492B1 BG 62492 B1 BG62492 B1 BG 62492B1 BG 99100 A BG99100 A BG 99100A BG 9910094 A BG9910094 A BG 9910094A BG 62492 B1 BG62492 B1 BG 62492B1
Authority
BG
Bulgaria
Prior art keywords
sialyltransferase
val
sequence
dna
gly
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
BG99100A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG99100A (bg
Inventor
James E. Paulson
Xiaohong Wen
Brian D. Livingston
William Gillespie
Sorge Kelm
Alma L. Burlingame
Katalin Medzihradszky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Regents of the University of California, San Diego
Cytel Corp
Original Assignee
Regents of the University of California, San Diego
Cytel Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regents of the University of California, San Diego, Cytel Corp filed Critical Regents of the University of California, San Diego
Publication of BG99100A publication Critical patent/BG99100A/bg
Publication of BG62492B1 publication Critical patent/BG62492B1/bg
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1081—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Ceramic Products (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BG99100A 1992-03-09 1994-10-07 Състави и методи за идентифициране и синтез насиалилтрансферази Expired - Lifetime BG62492B1 (bg)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US85035792A 1992-03-09 1992-03-09
US92536992A 1992-08-04 1992-08-04
PCT/US1993/002002 WO1993018157A1 (en) 1992-03-09 1993-03-09 Compositions and methods for the identification and synthesis of sialyltransferases

Publications (2)

Publication Number Publication Date
BG99100A BG99100A (bg) 1995-05-31
BG62492B1 true BG62492B1 (bg) 1999-12-30

Family

ID=27126928

Family Applications (1)

Application Number Title Priority Date Filing Date
BG99100A Expired - Lifetime BG62492B1 (bg) 1992-03-09 1994-10-07 Състави и методи за идентифициране и синтез насиалилтрансферази

Country Status (17)

Country Link
EP (1) EP0632831B1 (ko)
JP (1) JPH07505771A (ko)
KR (1) KR100300467B1 (ko)
AT (1) ATE228565T1 (ko)
AU (1) AU668714B2 (ko)
BG (1) BG62492B1 (ko)
CA (1) CA2131703C (ko)
CZ (1) CZ220494A3 (ko)
DE (1) DE69332520T2 (ko)
DK (1) DK0632831T3 (ko)
ES (1) ES2191011T3 (ko)
FI (1) FI119692B (ko)
HU (1) HU219260B (ko)
NO (1) NO314666B1 (ko)
NZ (1) NZ251096A (ko)
SK (1) SK108894A3 (ko)
WO (1) WO1993018157A1 (ko)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5384249A (en) * 1991-12-17 1995-01-24 Kyowa Hakko Kogyo Co., Ltd. α2→3 sialyltransferase
EP0871743A1 (en) * 1994-12-22 1998-10-21 Roche Diagnostics GmbH Isolated polysialyl transferases, nucleic acid molecules coding therefor, methods of production and use
US5849904A (en) * 1994-12-22 1998-12-15 Boehringer Mannheim Gmbh Isolated nucleic acid molecules which hybridize to polysialyl transferases
AUPN658795A0 (en) * 1995-11-15 1995-12-07 Commonwealth Scientific And Industrial Research Organisation Method of producing alpha 2, 3 sialyltransferase
US6355255B1 (en) 1998-12-07 2002-03-12 Regents Of The University Of Minnesota Streptococcal C5a peptidase vaccine
WO1999041390A2 (de) * 1998-02-12 1999-08-19 Aventis Research & Technologies Gmbh & Co. Kg Expressionsvektor zur herstellung von dead-proteinen
US6194178B1 (en) 1998-09-03 2001-02-27 Synsorb Biotech Inc. Method for the production of sialylated oligosaccharides
US7214660B2 (en) 2001-10-10 2007-05-08 Neose Technologies, Inc. Erythropoietin: remodeling and glycoconjugation of erythropoietin
US7173003B2 (en) 2001-10-10 2007-02-06 Neose Technologies, Inc. Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
EP2338333B1 (en) 2003-04-09 2017-09-06 ratiopharm GmbH Glycopegylation methods and proteins/peptides produced by the methods
WO2005012484A2 (en) 2003-07-25 2005-02-10 Neose Technologies, Inc. Antibody-toxin conjugates
US20080305992A1 (en) 2003-11-24 2008-12-11 Neose Technologies, Inc. Glycopegylated erythropoietin
WO2006010143A2 (en) 2004-07-13 2006-01-26 Neose Technologies, Inc. Branched peg remodeling and glycosylation of glucagon-like peptide-1 [glp-1]
US20080318296A1 (en) 2004-07-21 2008-12-25 Inokuchi Jin-Ichi Mutant Glycoprotein Resistant to Modification with Asparagine-Linked Sugar Chain
SI2586456T1 (sl) 2004-10-29 2016-05-31 Ratiopharm Gmbh Preoblikovanje in glikopegliacija fibroblastnega rastnega faktorja (FGF)
EP1858543B1 (en) 2005-01-10 2013-11-27 BioGeneriX AG Glycopegylated granulocyte colony stimulating factor
WO2006121569A2 (en) 2005-04-08 2006-11-16 Neose Technologies, Inc. Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
US20070105755A1 (en) 2005-10-26 2007-05-10 Neose Technologies, Inc. One pot desialylation and glycopegylation of therapeutic peptides
US20090048440A1 (en) 2005-11-03 2009-02-19 Neose Technologies, Inc. Nucleotide Sugar Purification Using Membranes
CN101516388B (zh) 2006-07-21 2012-10-31 诺和诺德公司 通过o-联糖基化序列的肽的糖基化
EP2054521A4 (en) 2006-10-03 2012-12-19 Novo Nordisk As METHODS OF PURIFYING CONJUGATES OF POLYPEPTIDES
ES2406267T3 (es) 2007-04-03 2013-06-06 Biogenerix Ag Métodos de tratamiento usando G-CSF glicopegilado
WO2008154639A2 (en) 2007-06-12 2008-12-18 Neose Technologies, Inc. Improved process for the production of nucleotide sugars
PL2257311T3 (pl) 2008-02-27 2014-09-30 Novo Nordisk As Koniugaty cząsteczek czynnika VIII
AR074273A1 (es) 2008-11-05 2011-01-05 Wyeth Corp Composicion inmunigenica de multiples componentes para la prevencion de la enfermedad estreptococica beta-hemolitica bhs. uso. metodo
CA3089231A1 (en) * 2018-01-23 2019-08-01 Virginia Commonwealth University Mda-7/il-24 secretory variants and methods of use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5059535A (en) * 1989-04-12 1991-10-22 Chembiomed, Ltd. Process for the separation and purification of sialyl transferases
US5032519A (en) * 1989-10-24 1991-07-16 The Regents Of The Univ. Of California Method for producing secretable glycosyltransferases and other Golgi processing enzymes
DE4028800A1 (de) * 1990-09-11 1992-03-12 Behringwerke Ag Gentechnische sialylierung von glykoproteinen
GB2256197B (en) * 1991-05-31 1995-11-22 Ciba Geigy Ag Yeast as host for expression of heterologous glycosyl transferase enzymes
SE9201544L (sv) * 1991-05-31 1992-12-01 Ciba Geigy Ag Saett att framstaella glykosyltransferaser

Also Published As

Publication number Publication date
BG99100A (bg) 1995-05-31
FI119692B (fi) 2009-02-13
NO943323L (no) 1994-11-01
NZ251096A (en) 1996-03-26
HU219260B (en) 2001-03-28
DE69332520T2 (de) 2003-09-11
ATE228565T1 (de) 2002-12-15
CA2131703C (en) 2007-08-21
HUT69933A (en) 1995-09-28
AU668714B2 (en) 1996-05-16
CZ220494A3 (en) 1995-03-15
HU9402586D0 (en) 1994-11-28
DK0632831T3 (da) 2003-03-24
FI944136A0 (fi) 1994-09-08
JPH07505771A (ja) 1995-06-29
DE69332520D1 (de) 2003-01-09
WO1993018157A1 (en) 1993-09-16
AU3791993A (en) 1993-10-05
CA2131703A1 (en) 1993-09-16
NO943323D0 (no) 1994-09-08
EP0632831A1 (en) 1995-01-11
NO314666B1 (no) 2003-04-28
SK108894A3 (en) 1995-07-11
EP0632831B1 (en) 2002-11-27
ES2191011T3 (es) 2003-09-01
KR100300467B1 (ko) 2001-10-22
FI944136A (fi) 1994-11-08

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