DE69332520D1 - Nukleinsäure, expressionsvektor und zusammensetzungen zur identifizierung und herstellung von rekombinanten sialyltransferasen - Google Patents
Nukleinsäure, expressionsvektor und zusammensetzungen zur identifizierung und herstellung von rekombinanten sialyltransferasenInfo
- Publication number
- DE69332520D1 DE69332520D1 DE69332520T DE69332520T DE69332520D1 DE 69332520 D1 DE69332520 D1 DE 69332520D1 DE 69332520 T DE69332520 T DE 69332520T DE 69332520 T DE69332520 T DE 69332520T DE 69332520 D1 DE69332520 D1 DE 69332520D1
- Authority
- DE
- Germany
- Prior art keywords
- recombinant
- compositions
- identification
- preparation
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1081—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Ceramic Products (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US85035792A | 1992-03-09 | 1992-03-09 | |
US92536992A | 1992-08-04 | 1992-08-04 | |
PCT/US1993/002002 WO1993018157A1 (en) | 1992-03-09 | 1993-03-09 | Compositions and methods for the identification and synthesis of sialyltransferases |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69332520D1 true DE69332520D1 (de) | 2003-01-09 |
DE69332520T2 DE69332520T2 (de) | 2003-09-11 |
Family
ID=27126928
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69332520T Expired - Lifetime DE69332520T2 (de) | 1992-03-09 | 1993-03-09 | Nukleinsäure, expressionsvektor und zusammensetzungen zur identifizierung und herstellung von rekombinanten sialyltransferasen |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP0632831B1 (de) |
JP (1) | JPH07505771A (de) |
KR (1) | KR100300467B1 (de) |
AT (1) | ATE228565T1 (de) |
AU (1) | AU668714B2 (de) |
BG (1) | BG62492B1 (de) |
CA (1) | CA2131703C (de) |
CZ (1) | CZ220494A3 (de) |
DE (1) | DE69332520T2 (de) |
DK (1) | DK0632831T3 (de) |
ES (1) | ES2191011T3 (de) |
FI (1) | FI119692B (de) |
HU (1) | HU219260B (de) |
NO (1) | NO314666B1 (de) |
NZ (1) | NZ251096A (de) |
SK (1) | SK108894A3 (de) |
WO (1) | WO1993018157A1 (de) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5384249A (en) * | 1991-12-17 | 1995-01-24 | Kyowa Hakko Kogyo Co., Ltd. | α2→3 sialyltransferase |
US5849904A (en) * | 1994-12-22 | 1998-12-15 | Boehringer Mannheim Gmbh | Isolated nucleic acid molecules which hybridize to polysialyl transferases |
AU692355B2 (en) * | 1994-12-22 | 1998-06-04 | Boehringer Mannheim Gmbh | Isolated polysialyl transferases, nucleic acid molecules coding therefor, methods of production and use |
AUPN658795A0 (en) * | 1995-11-15 | 1995-12-07 | Commonwealth Scientific And Industrial Research Organisation | Method of producing alpha 2, 3 sialyltransferase |
US6355255B1 (en) * | 1998-12-07 | 2002-03-12 | Regents Of The University Of Minnesota | Streptococcal C5a peptidase vaccine |
CA2320517A1 (en) * | 1998-02-12 | 1999-08-19 | Aventis Research & Technologies Gmbh & Co. Kg | Expression vector for the production of dead proteins |
US6194178B1 (en) | 1998-09-03 | 2001-02-27 | Synsorb Biotech Inc. | Method for the production of sialylated oligosaccharides |
US7173003B2 (en) | 2001-10-10 | 2007-02-06 | Neose Technologies, Inc. | Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF |
US7214660B2 (en) | 2001-10-10 | 2007-05-08 | Neose Technologies, Inc. | Erythropoietin: remodeling and glycoconjugation of erythropoietin |
JP4674702B2 (ja) | 2003-04-09 | 2011-04-20 | バイオジェネリクス エージー | グリコペギレ−ション法およびその方法により生成されたタンパク質/ペプチド |
WO2005012484A2 (en) | 2003-07-25 | 2005-02-10 | Neose Technologies, Inc. | Antibody-toxin conjugates |
US20080305992A1 (en) | 2003-11-24 | 2008-12-11 | Neose Technologies, Inc. | Glycopegylated erythropoietin |
EP1771066A2 (de) | 2004-07-13 | 2007-04-11 | Neose Technologies, Inc. | Remodellierung von verzweigtem peg und klykolysierung von glucagonähnlichem peptide-1 glp-1 |
KR101324681B1 (ko) | 2004-07-21 | 2013-11-04 | 세이가가쿠 고교 가부시키가이샤 | 아스파라긴 결합형 당쇄 수식을 받지않은 변이형 당단백질 |
HUE026826T2 (en) | 2004-10-29 | 2016-07-28 | Ratiopharm Gmbh | Modeling and glycopegylation of fibroblast growth factor (FGF) |
JP4951527B2 (ja) | 2005-01-10 | 2012-06-13 | バイオジェネリックス アーゲー | 糖peg化顆粒球コロニー刺激因子 |
US20070154992A1 (en) | 2005-04-08 | 2007-07-05 | Neose Technologies, Inc. | Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants |
US20070105755A1 (en) | 2005-10-26 | 2007-05-10 | Neose Technologies, Inc. | One pot desialylation and glycopegylation of therapeutic peptides |
WO2007056191A2 (en) | 2005-11-03 | 2007-05-18 | Neose Technologies, Inc. | Nucleotide sugar purification using membranes |
CN101516388B (zh) | 2006-07-21 | 2012-10-31 | 诺和诺德公司 | 通过o-联糖基化序列的肽的糖基化 |
JP2010505874A (ja) | 2006-10-03 | 2010-02-25 | ノヴォ ノルディスク アー/エス | ポリペプチドコンジュゲートの精製方法 |
ES2406267T3 (es) | 2007-04-03 | 2013-06-06 | Biogenerix Ag | Métodos de tratamiento usando G-CSF glicopegilado |
MX2009013259A (es) | 2007-06-12 | 2010-01-25 | Novo Nordisk As | Proceso mejorado para la produccion de azucares de nucleotidos. |
AU2009219232B2 (en) | 2008-02-27 | 2014-02-27 | Novo Nordisk A/S | Conjugated Factor VIII molecules |
AU2009313615B2 (en) | 2008-11-05 | 2012-11-29 | Regents Of The University Of Minnesota | Multicomponent immunogenic composition for the prevention of beta-hemolytic streptococcal (BHS) disease |
WO2019147623A2 (en) * | 2018-01-23 | 2019-08-01 | Virginia Commonwealth University | Mda-7/il secretory variants and methods of use |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5059535A (en) * | 1989-04-12 | 1991-10-22 | Chembiomed, Ltd. | Process for the separation and purification of sialyl transferases |
US5032519A (en) * | 1989-10-24 | 1991-07-16 | The Regents Of The Univ. Of California | Method for producing secretable glycosyltransferases and other Golgi processing enzymes |
DE4028800A1 (de) * | 1990-09-11 | 1992-03-12 | Behringwerke Ag | Gentechnische sialylierung von glykoproteinen |
SE9201544L (sv) * | 1991-05-31 | 1992-12-01 | Ciba Geigy Ag | Saett att framstaella glykosyltransferaser |
GB2256197B (en) * | 1991-05-31 | 1995-11-22 | Ciba Geigy Ag | Yeast as host for expression of heterologous glycosyl transferase enzymes |
-
1993
- 1993-03-09 NZ NZ251096A patent/NZ251096A/en not_active IP Right Cessation
- 1993-03-09 EP EP93907244A patent/EP0632831B1/de not_active Expired - Lifetime
- 1993-03-09 ES ES93907244T patent/ES2191011T3/es not_active Expired - Lifetime
- 1993-03-09 AT AT93907244T patent/ATE228565T1/de active
- 1993-03-09 SK SK1088-94A patent/SK108894A3/sk unknown
- 1993-03-09 CZ CZ942204A patent/CZ220494A3/cs unknown
- 1993-03-09 DE DE69332520T patent/DE69332520T2/de not_active Expired - Lifetime
- 1993-03-09 HU HU9402586A patent/HU219260B/hu unknown
- 1993-03-09 DK DK93907244T patent/DK0632831T3/da active
- 1993-03-09 JP JP5515911A patent/JPH07505771A/ja active Pending
- 1993-03-09 AU AU37919/93A patent/AU668714B2/en not_active Expired
- 1993-03-09 CA CA002131703A patent/CA2131703C/en not_active Expired - Lifetime
- 1993-03-09 WO PCT/US1993/002002 patent/WO1993018157A1/en active IP Right Grant
-
1994
- 1994-09-08 NO NO19943323A patent/NO314666B1/no not_active IP Right Cessation
- 1994-09-08 FI FI944136A patent/FI119692B/fi not_active IP Right Cessation
- 1994-09-09 KR KR940703163A patent/KR100300467B1/ko active
- 1994-10-07 BG BG99100A patent/BG62492B1/bg not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
FI944136A (fi) | 1994-11-08 |
JPH07505771A (ja) | 1995-06-29 |
HUT69933A (en) | 1995-09-28 |
NZ251096A (en) | 1996-03-26 |
CZ220494A3 (en) | 1995-03-15 |
AU3791993A (en) | 1993-10-05 |
DE69332520T2 (de) | 2003-09-11 |
HU219260B (en) | 2001-03-28 |
FI944136A0 (fi) | 1994-09-08 |
HU9402586D0 (en) | 1994-11-28 |
AU668714B2 (en) | 1996-05-16 |
ATE228565T1 (de) | 2002-12-15 |
WO1993018157A1 (en) | 1993-09-16 |
NO943323D0 (no) | 1994-09-08 |
NO314666B1 (no) | 2003-04-28 |
NO943323L (no) | 1994-11-01 |
DK0632831T3 (da) | 2003-03-24 |
EP0632831B1 (de) | 2002-11-27 |
CA2131703A1 (en) | 1993-09-16 |
SK108894A3 (en) | 1995-07-11 |
ES2191011T3 (es) | 2003-09-01 |
BG99100A (bg) | 1995-05-31 |
KR100300467B1 (de) | 2001-10-22 |
CA2131703C (en) | 2007-08-21 |
BG62492B1 (bg) | 1999-12-30 |
FI119692B (fi) | 2009-02-13 |
EP0632831A1 (de) | 1995-01-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: NEOSE TECHNOLOGIES, INC., HORSHAM, PA., US Owner name: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, O, US |
|
8327 | Change in the person/name/address of the patent owner |
Owner name: NOVO NORDISK A/S, BAGSVAERD, DK Owner name: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, O, US |