ES2191011T3 - Acido nucleico, vector de expresion y composiciones para la identificacion y sintesis de sialiltransferasas recombinantes. - Google Patents

Acido nucleico, vector de expresion y composiciones para la identificacion y sintesis de sialiltransferasas recombinantes.

Info

Publication number
ES2191011T3
ES2191011T3 ES93907244T ES93907244T ES2191011T3 ES 2191011 T3 ES2191011 T3 ES 2191011T3 ES 93907244 T ES93907244 T ES 93907244T ES 93907244 T ES93907244 T ES 93907244T ES 2191011 T3 ES2191011 T3 ES 2191011T3
Authority
ES
Spain
Prior art keywords
recombinant
sialiltranspherases
synthesis
compositions
identification
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93907244T
Other languages
English (en)
Inventor
James C Paulson
Xiaohong Wen
Brian Livingston
William Gillespie
Sorge Kelm
Alma L Burlingame
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
Cytel Corp
Original Assignee
University of California
Cytel Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California, Cytel Corp filed Critical University of California
Application granted granted Critical
Publication of ES2191011T3 publication Critical patent/ES2191011T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1081—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Ceramic Products (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

SE PRESENTAN DNA''S AISLADOS QUE CODIFICAN LA SIALILTRANSFERASA QUE CONTIENEN UNA REGION CONSERVADA DE HOMOLOGIA ASI COMO METODOS PARA OBTENER DICHO DNA, JUNTO CON SISTEMAS DE EXPRESION PARA LA PRODUCCION RECOMBINANTE DE LA SIALILTRANSFERASA.
ES93907244T 1992-03-09 1993-03-09 Acido nucleico, vector de expresion y composiciones para la identificacion y sintesis de sialiltransferasas recombinantes. Expired - Lifetime ES2191011T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85035792A 1992-03-09 1992-03-09
US92536992A 1992-08-04 1992-08-04

Publications (1)

Publication Number Publication Date
ES2191011T3 true ES2191011T3 (es) 2003-09-01

Family

ID=27126928

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93907244T Expired - Lifetime ES2191011T3 (es) 1992-03-09 1993-03-09 Acido nucleico, vector de expresion y composiciones para la identificacion y sintesis de sialiltransferasas recombinantes.

Country Status (17)

Country Link
EP (1) EP0632831B1 (es)
JP (1) JPH07505771A (es)
KR (1) KR100300467B1 (es)
AT (1) ATE228565T1 (es)
AU (1) AU668714B2 (es)
BG (1) BG62492B1 (es)
CA (1) CA2131703C (es)
CZ (1) CZ220494A3 (es)
DE (1) DE69332520T2 (es)
DK (1) DK0632831T3 (es)
ES (1) ES2191011T3 (es)
FI (1) FI119692B (es)
HU (1) HU219260B (es)
NO (1) NO314666B1 (es)
NZ (1) NZ251096A (es)
SK (1) SK108894A3 (es)
WO (1) WO1993018157A1 (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5384249A (en) * 1991-12-17 1995-01-24 Kyowa Hakko Kogyo Co., Ltd. α2→3 sialyltransferase
WO1996020280A1 (en) * 1994-12-22 1996-07-04 Boehringer Mannheim Gmbh Isolated polysialyl transferases, nucleic acid molecules coding therefor, methods of production and use
US5849904A (en) * 1994-12-22 1998-12-15 Boehringer Mannheim Gmbh Isolated nucleic acid molecules which hybridize to polysialyl transferases
AUPN658795A0 (en) * 1995-11-15 1995-12-07 Commonwealth Scientific And Industrial Research Organisation Method of producing alpha 2, 3 sialyltransferase
US6355255B1 (en) 1998-12-07 2002-03-12 Regents Of The University Of Minnesota Streptococcal C5a peptidase vaccine
AU755517B2 (en) * 1998-02-12 2002-12-12 Aventis Research & Technologies Gmbh & Co. Kg Expression vector for the production of dead proteins
US6194178B1 (en) 1998-09-03 2001-02-27 Synsorb Biotech Inc. Method for the production of sialylated oligosaccharides
US7214660B2 (en) 2001-10-10 2007-05-08 Neose Technologies, Inc. Erythropoietin: remodeling and glycoconjugation of erythropoietin
US7173003B2 (en) 2001-10-10 2007-02-06 Neose Technologies, Inc. Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
MXPA05010773A (es) 2003-04-09 2005-12-12 Neose Technologies Inc Metodos de glicopegilacion y proteinas/peptidos producidos por los metodos.
WO2005012484A2 (en) 2003-07-25 2005-02-10 Neose Technologies, Inc. Antibody-toxin conjugates
US20080305992A1 (en) 2003-11-24 2008-12-11 Neose Technologies, Inc. Glycopegylated erythropoietin
US20080300173A1 (en) 2004-07-13 2008-12-04 Defrees Shawn Branched Peg Remodeling and Glycosylation of Glucagon-Like Peptides-1 [Glp-1]
US20080318296A1 (en) 2004-07-21 2008-12-25 Inokuchi Jin-Ichi Mutant Glycoprotein Resistant to Modification with Asparagine-Linked Sugar Chain
JP5948627B2 (ja) 2004-10-29 2016-07-20 レイショファーム ゲーエムベーハー 線維芽細胞成長因子（ｆｇｆ）のリモデリングと糖質ペグ化
EP1858543B1 (en) 2005-01-10 2013-11-27 BioGeneriX AG Glycopegylated granulocyte colony stimulating factor
US20070154992A1 (en) 2005-04-08 2007-07-05 Neose Technologies, Inc. Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
US20070105755A1 (en) 2005-10-26 2007-05-10 Neose Technologies, Inc. One pot desialylation and glycopegylation of therapeutic peptides
US20090048440A1 (en) 2005-11-03 2009-02-19 Neose Technologies, Inc. Nucleotide Sugar Purification Using Membranes
CN101516388B (zh) 2006-07-21 2012-10-31 诺和诺德公司 通过o-联糖基化序列的肽的糖基化
EP2054521A4 (en) 2006-10-03 2012-12-19 Novo Nordisk As METHODS OF PURIFYING CONJUGATES OF POLYPEPTIDES
RS52845B (en) 2007-04-03 2013-12-31 Biogenerix Ag TREATMENT PROCEDURES USING GLYCOPEGILATED G-CSF
US9493499B2 (en) 2007-06-12 2016-11-15 Novo Nordisk A/S Process for the production of purified cytidinemonophosphate-sialic acid-polyalkylene oxide (CMP-SA-PEG) as modified nucleotide sugars via anion exchange chromatography
EP2257311B1 (en) 2008-02-27 2014-04-16 Novo Nordisk A/S Conjugated factor viii molecules
KR20110081282A (ko) 2008-11-05 2011-07-13 와이어쓰 엘엘씨 베타―용혈성 연쇄구균 (ｂｈｓ) 질환의 예방을 위한 다성분 면역원성 조성물
US20200354745A1 (en) * 2018-01-23 2020-11-12 Paul B. Fisher Mda-7/il secretory variants and methods of use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5059535A (en) * 1989-04-12 1991-10-22 Chembiomed, Ltd. Process for the separation and purification of sialyl transferases
US5032519A (en) * 1989-10-24 1991-07-16 The Regents Of The Univ. Of California Method for producing secretable glycosyltransferases and other Golgi processing enzymes
DE4028800A1 (de) * 1990-09-11 1992-03-12 Behringwerke Ag Gentechnische sialylierung von glykoproteinen
GB2256197B (en) * 1991-05-31 1995-11-22 Ciba Geigy Ag Yeast as host for expression of heterologous glycosyl transferase enzymes
SE9201544L (sv) * 1991-05-31 1992-12-01 Ciba Geigy Ag Saett att framstaella glykosyltransferaser

Also Published As

Publication number Publication date
DK0632831T3 (da) 2003-03-24
FI944136A (fi) 1994-11-08
SK108894A3 (en) 1995-07-11
FI944136A0 (fi) 1994-09-08
EP0632831B1 (en) 2002-11-27
CA2131703C (en) 2007-08-21
AU3791993A (en) 1993-10-05
DE69332520T2 (de) 2003-09-11
HU219260B (en) 2001-03-28
WO1993018157A1 (en) 1993-09-16
BG99100A (bg) 1995-05-31
DE69332520D1 (de) 2003-01-09
BG62492B1 (bg) 1999-12-30
HUT69933A (en) 1995-09-28
HU9402586D0 (en) 1994-11-28
JPH07505771A (ja) 1995-06-29
CA2131703A1 (en) 1993-09-16
KR100300467B1 (es) 2001-10-22
AU668714B2 (en) 1996-05-16
NO943323L (no) 1994-11-01
CZ220494A3 (en) 1995-03-15
FI119692B (fi) 2009-02-13
NZ251096A (en) 1996-03-26
NO314666B1 (no) 2003-04-28
NO943323D0 (no) 1994-09-08
EP0632831A1 (en) 1995-01-11
ATE228565T1 (de) 2002-12-15

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