BG62333B1 - Нови съединения от клас секомакролиди и секоазалиди и методза получаването им - Google Patents

Нови съединения от клас секомакролиди и секоазалиди и методза получаването им Download PDF

Info

Publication number
BG62333B1
BG62333B1 BG100164A BG10016495A BG62333B1 BG 62333 B1 BG62333 B1 BG 62333B1 BG 100164 A BG100164 A BG 100164A BG 10016495 A BG10016495 A BG 10016495A BG 62333 B1 BG62333 B1 BG 62333B1
Authority
BG
Bulgaria
Prior art keywords
group
same
denote
compound
coh
Prior art date
Application number
BG100164A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG100164A (bg
Inventor
Gorjana Lazarevski
Gabrijela Kobrehel
Original Assignee
Pliva Farmaceutska
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pliva Farmaceutska filed Critical Pliva Farmaceutska
Publication of BG100164A publication Critical patent/BG100164A/bg
Publication of BG62333B1 publication Critical patent/BG62333B1/bg

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/04Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26Acyclic or carbocyclic radicals, substituted by hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
BG100164A 1995-03-27 1995-11-24 Нови съединения от клас секомакролиди и секоазалиди и методза получаването им BG62333B1 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HR950145A HRP950145A2 (en) 1995-03-27 1995-03-27 New compounds of the secomacrolide and secoazalide class and a process for the preparation thereof

Publications (2)

Publication Number Publication Date
BG100164A BG100164A (bg) 1996-11-29
BG62333B1 true BG62333B1 (bg) 1999-08-31

Family

ID=10946231

Family Applications (1)

Application Number Title Priority Date Filing Date
BG100164A BG62333B1 (bg) 1995-03-27 1995-11-24 Нови съединения от клас секомакролиди и секоазалиди и методза получаването им

Country Status (13)

Country Link
US (1) US5721346A (fr)
EP (1) EP0735041A1 (fr)
JP (1) JPH08269078A (fr)
CN (1) CN1053911C (fr)
BG (1) BG62333B1 (fr)
CA (1) CA2164152C (fr)
CZ (1) CZ313495A3 (fr)
HR (1) HRP950145A2 (fr)
PL (1) PL312209A1 (fr)
RO (1) RO116017B1 (fr)
RU (1) RU2130936C1 (fr)
SI (1) SI9500358A (fr)
SK (1) SK152195A3 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP970141A2 (en) * 1997-03-12 1999-02-28 Banić-Tomaueić Zrinka New secomacrolydes of erythromicin a, and a process for the preparation thereof
CZ211798A3 (cs) * 1997-07-16 1999-02-17 Pliva, Farmaceutska, Kemijska, Prehrambena I Kozmetička Industrije, Dioničko Društvo Lineární 8a-sekoazalidy a způsob jejich výroby
HUP0104192A3 (en) 1998-11-03 2003-12-29 Pfizer Prod Inc Novel macrolide antibiotics
JPWO2005019238A1 (ja) * 2003-08-22 2006-10-19 明治製菓株式会社 新規アザライド及びアザラクタム誘導体とその製造法
GB201608236D0 (en) * 2016-05-11 2016-06-22 Fidelta D O O Seco macrolide compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5210235A (en) * 1992-08-26 1993-05-11 Merck & Co., Inc. Methods of elaborating erythromycin fragments into amine-containing fragments of azalide antibiotics
WO1994015617A1 (fr) * 1993-01-11 1994-07-21 Merck & Co., Inc. Antibiotiques macrolides 8a-aza et 9a-aza, et leurs procedes de preparation et d'utilisation

Also Published As

Publication number Publication date
SK152195A3 (en) 1997-07-09
CZ313495A3 (en) 1997-08-13
BG100164A (bg) 1996-11-29
CN1133294A (zh) 1996-10-16
CA2164152A1 (fr) 1996-09-28
HRP950145A2 (en) 1997-08-31
EP0735041A1 (fr) 1996-10-02
CA2164152C (fr) 2000-03-28
SI9500358A (en) 1996-10-31
CN1053911C (zh) 2000-06-28
RU2130936C1 (ru) 1999-05-27
PL312209A1 (en) 1996-09-30
US5721346A (en) 1998-02-24
RO116017B1 (ro) 2000-09-29
JPH08269078A (ja) 1996-10-15

Similar Documents

Publication Publication Date Title
KR101945324B1 (ko) 매크로라이드들 및 케톨라이드들과 이의 중간체들을 제조하는 공정들
RU2045533C1 (ru) О-метильные производные азитромицина а, обладающие антибактериальной активностью, азитромицины в качестве промежуточных соединений для получения о-метильных производных азитромицина а и способ получения о-метильных производных азитромицина а
US4474768A (en) N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
EP0180415B1 (fr) Dérivé de la 6-0-méthylérythromycine
RU2192427C2 (ru) Производные эритромицина, обладающие антибактериальной активностью, способ их получения (варианты), фармацевтическая композиция и способ регулирования бактериальной инфекции у млекопитающего
CS241069B2 (en) Method of 4"-epi-9-deoxo-9a-methyl-9a-aza-9a-homoerythromycine a preparation
CZ303474B6 (cs) 6-O-substituovaný ketolidový derivát erythromycinu, zpusob jeho prípravy, jeho použití a farmaceutická kompozice ho obsahující
CA2327775C (fr) Cetolides de lactame a 15 elements doues d'activite antimicrobienne
US4464527A (en) Antibacterial 9-deoxo-9a-alkyl-9a-aza-9a-homoerythromycin A derivatives and intermediates therefore
NZ203417A (en) 4"-epi-erythromycin a and derivatives and pharmaceutical compositions
JP3056035B2 (ja) 9−デオキソ−9a−アザ−11−デオキシ−9a−ホモエリスロマイシンA 9a,11−環式カルバメート
BG62333B1 (bg) Нови съединения от клас секомакролиди и секоазалиди и методза получаването им
CZ20032216A3 (cs) 9a-N[N´-(Fenylsulfonyl)karbamoyl]deriváty 9-deoxo-9-dihydro-9a-aza-9a-homoerythromycinu A a 5-O-desosaminyl-9-deoxo-9-dihydro-9a-aza-9a-homoerythronolidu A
SK15702001A3 (sk) Halogénderiváty 9-deoxo-9a-aza-9a-homoerytromycínu A
EP1140962B1 (fr) Nouveaux derives de la classe des oleandomycines
HUT74073A (en) New compounds of the secomacrolide and secoazalide class and a process for the preparation thereof
CN1066455C (zh) 从红霉素类衍生的新的断大环内酯类及其制备方法
JPH0136834B2 (fr)
JP2006507315A (ja) 9−デオキソ−9−ジヒドロ−9a−アザ−9a−ホモエリスロマイシンA及び5−O−デソサミニル−9−デオキソ−9−ジヒドロ−9a−アザ−9a−ホモエリスロノリドAの置換した9a−N−{N’−[4−(スルホニル)フェニルカルバモイル]}誘導体
JPH06247996A (ja) 6−o−メチルエリスロマイシンa誘導体
CS241099B2 (cs) Způsob přípravy 4“-epi-9-deoxo-9a-methyl-9a-aza- -9a-bomoerythromycinu A
Bairamova et al. Synthesis of the principal chain of the o-antigenic polysaccharides of Shigella flexneri. Communication 2. Synthesis of 4-o-benzoyl-1, 2-o-(1-(cyanoethylidene)-β-L-rhamnopyranose