BG61186B1 - Цис-2,3,3а,4,5,9в-хексахидро-1н-бензо(е)- индолови производни - Google Patents

Цис-2,3,3а,4,5,9в-хексахидро-1н-бензо(е)- индолови производни Download PDF

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Publication number
BG61186B1
BG61186B1 BG97201A BG9720192A BG61186B1 BG 61186 B1 BG61186 B1 BG 61186B1 BG 97201 A BG97201 A BG 97201A BG 9720192 A BG9720192 A BG 9720192A BG 61186 B1 BG61186 B1 BG 61186B1
Authority
BG
Bulgaria
Prior art keywords
benzo
cis
hexahydro
indol
racemic
Prior art date
Application number
BG97201A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG97201A (bg
Inventor
Hans Bruderer
Thierry Godel
Rene Imhof
Roland Jakob-Roetne
Original Assignee
F. Hoffmann- La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann- La Roche Ag filed Critical F. Hoffmann- La Roche Ag
Publication of BG97201A publication Critical patent/BG97201A/bg
Publication of BG61186B1 publication Critical patent/BG61186B1/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/60—Naphtho [b] pyrroles; Hydrogenated naphtho [b] pyrroles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BG97201A 1991-12-20 1992-12-18 Цис-2,3,3а,4,5,9в-хексахидро-1н-бензо(е)- индолови производни BG61186B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH380691 1991-12-20
CH325492 1992-10-19

Publications (2)

Publication Number Publication Date
BG97201A BG97201A (bg) 1993-12-24
BG61186B1 true BG61186B1 (bg) 1997-02-28

Family

ID=25692569

Family Applications (1)

Application Number Title Priority Date Filing Date
BG97201A BG61186B1 (bg) 1991-12-20 1992-12-18 Цис-2,3,3а,4,5,9в-хексахидро-1н-бензо(е)- индолови производни

Country Status (21)

Country Link
US (2) US5318966A (enExample)
EP (1) EP0548664B1 (enExample)
JP (1) JPH07119215B2 (enExample)
CN (1) CN1037510C (enExample)
AT (1) ATE123277T1 (enExample)
AU (1) AU661076B2 (enExample)
BG (1) BG61186B1 (enExample)
CA (1) CA2084442A1 (enExample)
CZ (1) CZ381092A3 (enExample)
DE (1) DE59202406D1 (enExample)
DK (1) DK0548664T3 (enExample)
ES (1) ES2073847T3 (enExample)
FI (1) FI925774L (enExample)
GR (1) GR3017256T3 (enExample)
HU (2) HUT68178A (enExample)
IL (1) IL104080A (enExample)
IS (1) IS3961A (enExample)
MY (1) MY108026A (enExample)
NO (1) NO179325C (enExample)
NZ (1) NZ245463A (enExample)
TW (1) TW239127B (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5486611A (en) * 1989-07-13 1996-01-23 The Upjohn Company Carboxamido-(1,2N)-carbocyclic-2-aminotetralin derivatives
AU648032B2 (en) * 1989-07-13 1994-04-14 Pharmacia & Upjohn Company (1,2N) and (3,2N)-carbocyclic-2-amino tetralin derivatives
ATE178893T1 (de) * 1990-01-11 1999-04-15 Upjohn Co 6,7,8,9-tetrahydro-3h-benz(e)indolheterocyclen mit wirkung auf das zentrale nervensystem
US5434170A (en) * 1993-12-23 1995-07-18 Andrulis Pharmaceuticals Corp. Method for treating neurocognitive disorders
MX9700696A (es) * 1994-07-27 1997-04-30 Sankyo Co Compuestos heterociclicos, utiles como productores de efecto aloesterico en receptores muscarinicos.
US5859295A (en) * 1994-12-05 1999-01-12 University Of Kentucky Research Foundation Canavanine analogs and their use as chemotherapeutic agents
IL117149A0 (en) * 1995-02-23 1996-06-18 Schering Corp Muscarinic antagonists
US5889006A (en) * 1995-02-23 1999-03-30 Schering Corporation Muscarinic antagonists
GB9612153D0 (en) * 1996-06-11 1996-08-14 Smithkline Beecham Plc Compounds
EP2963041A1 (en) * 2014-07-02 2016-01-06 Laboratorios Del. Dr. Esteve, S.A. Tricyclic triazolic compounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1277789A (en) * 1969-09-08 1972-06-14 Logeais Labor Jacques Improvements in or relating to new polycyclic pyrrole derivatives
JPS4930836B1 (enExample) * 1971-07-22 1974-08-16
JPS4916862A (enExample) * 1972-06-14 1974-02-14
SE8004002L (sv) * 1980-05-29 1981-11-30 Arvidsson Folke Lars Erik Terapeutiskt anvendbara tetralinderivat
SE8302361D0 (sv) * 1983-04-27 1983-04-27 Astra Laekemedel Ab New tricyclic amines
JP2785879B2 (ja) * 1989-05-31 1998-08-13 ジ・アップジョン・カンパニー 治療学的に有用な２―アミノテトラリン誘導体
AU648032B2 (en) * 1989-07-13 1994-04-14 Pharmacia & Upjohn Company (1,2N) and (3,2N)-carbocyclic-2-amino tetralin derivatives

Also Published As

Publication number Publication date
DE59202406D1 (de) 1995-07-06
CN1037510C (zh) 1998-02-25
AU661076B2 (en) 1995-07-13
BG97201A (bg) 1993-12-24
NO924829D0 (no) 1992-12-14
US5318966A (en) 1994-06-07
DK0548664T3 (da) 1995-09-04
US5318967A (en) 1994-06-07
NO179325B (no) 1996-06-10
ES2073847T3 (es) 1995-08-16
NZ245463A (en) 1995-05-26
IL104080A (en) 1997-04-15
MY108026A (en) 1996-07-30
TW239127B (enExample) 1995-01-21
CZ381092A3 (en) 1993-09-15
IL104080A0 (en) 1993-05-13
CN1088576A (zh) 1994-06-29
JPH06128228A (ja) 1994-05-10
FI925774A7 (fi) 1993-06-21
NO179325C (no) 1996-09-18
GR3017256T3 (en) 1995-11-30
HU9203956D0 (en) 1993-03-29
FI925774L (fi) 1993-06-21
AU3018692A (en) 1993-06-24
EP0548664B1 (de) 1995-05-31
NO924829L (no) 1993-06-21
HUT68178A (en) 1995-05-29
JPH07119215B2 (ja) 1995-12-20
ATE123277T1 (de) 1995-06-15
IS3961A (is) 1993-06-21
FI925774A0 (fi) 1992-12-18
EP0548664A1 (de) 1993-06-30
CA2084442A1 (en) 1993-06-21

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