NZ245463A - Cis-2,3,3a,4,5,9b-hexahydro-1h-benzo[e]indole derivatives, preparation and pharmaceutical compositions thereof - Google Patents

Cis-2,3,3a,4,5,9b-hexahydro-1h-benzo[e]indole derivatives, preparation and pharmaceutical compositions thereof

Info

Publication number
NZ245463A
NZ245463A NZ245463A NZ24546392A NZ245463A NZ 245463 A NZ245463 A NZ 245463A NZ 245463 A NZ245463 A NZ 245463A NZ 24546392 A NZ24546392 A NZ 24546392A NZ 245463 A NZ245463 A NZ 245463A
Authority
NZ
New Zealand
Prior art keywords
cis
hexahydro
benzo
rac
indol
Prior art date
Application number
NZ245463A
Other languages
English (en)
Inventor
Hans Bruderer
Thierry Godel
Rene Imhof
Roland Jakob-Roetne
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NZ245463A publication Critical patent/NZ245463A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/60—Naphtho [b] pyrroles; Hydrogenated naphtho [b] pyrroles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Psychiatry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NZ245463A 1991-12-20 1992-12-14 Cis-2,3,3a,4,5,9b-hexahydro-1h-benzo[e]indole derivatives, preparation and pharmaceutical compositions thereof NZ245463A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH380691 1991-12-20
CH325492 1992-10-19

Publications (1)

Publication Number Publication Date
NZ245463A true NZ245463A (en) 1995-05-26

Family

ID=25692569

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ245463A NZ245463A (en) 1991-12-20 1992-12-14 Cis-2,3,3a,4,5,9b-hexahydro-1h-benzo[e]indole derivatives, preparation and pharmaceutical compositions thereof

Country Status (21)

Country Link
US (2) US5318966A (enExample)
EP (1) EP0548664B1 (enExample)
JP (1) JPH07119215B2 (enExample)
CN (1) CN1037510C (enExample)
AT (1) ATE123277T1 (enExample)
AU (1) AU661076B2 (enExample)
BG (1) BG61186B1 (enExample)
CA (1) CA2084442A1 (enExample)
CZ (1) CZ381092A3 (enExample)
DE (1) DE59202406D1 (enExample)
DK (1) DK0548664T3 (enExample)
ES (1) ES2073847T3 (enExample)
FI (1) FI925774A7 (enExample)
GR (1) GR3017256T3 (enExample)
HU (2) HUT68178A (enExample)
IL (1) IL104080A (enExample)
IS (1) IS3961A (enExample)
MY (1) MY108026A (enExample)
NO (1) NO179325C (enExample)
NZ (1) NZ245463A (enExample)
TW (1) TW239127B (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE152708T1 (de) * 1989-07-13 1997-05-15 Upjohn Co (1,2n) und (3,2n)-karbozyklische-2-amino- tetralinderivate
US5486611A (en) * 1989-07-13 1996-01-23 The Upjohn Company Carboxamido-(1,2N)-carbocyclic-2-aminotetralin derivatives
CA2073340C (en) * 1990-01-11 1997-05-20 Hakan Vilhelm Wikstrom Centrally acting 6,7,8,9-tetrahydro-3h-benz(e)indole heterocyclics
US5434170A (en) * 1993-12-23 1995-07-18 Andrulis Pharmaceuticals Corp. Method for treating neurocognitive disorders
NZ290199A (en) * 1994-07-27 1999-06-29 Sankyo Co Nitrogen containing heterocyclic compounds, selective allosteric effectors to regulate m1 receptors
US5859295A (en) * 1994-12-05 1999-01-12 University Of Kentucky Research Foundation Canavanine analogs and their use as chemotherapeutic agents
IL117149A0 (en) * 1995-02-23 1996-06-18 Schering Corp Muscarinic antagonists
US5889006A (en) * 1995-02-23 1999-03-30 Schering Corporation Muscarinic antagonists
GB9612153D0 (en) * 1996-06-11 1996-08-14 Smithkline Beecham Plc Compounds
EP2963041A1 (en) * 2014-07-02 2016-01-06 Laboratorios Del. Dr. Esteve, S.A. Tricyclic triazolic compounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1277789A (en) * 1969-09-08 1972-06-14 Logeais Labor Jacques Improvements in or relating to new polycyclic pyrrole derivatives
JPS4930836B1 (enExample) * 1971-07-22 1974-08-16
JPS4916862A (enExample) * 1972-06-14 1974-02-14
SE8004002L (sv) * 1980-05-29 1981-11-30 Arvidsson Folke Lars Erik Terapeutiskt anvendbara tetralinderivat
SE8302361D0 (sv) * 1983-04-27 1983-04-27 Astra Laekemedel Ab New tricyclic amines
CA2051399C (en) * 1989-05-31 2003-12-30 Chiu-Hong Lin Therapeutically useful 2-aminotetralin derivatives
ATE152708T1 (de) * 1989-07-13 1997-05-15 Upjohn Co (1,2n) und (3,2n)-karbozyklische-2-amino- tetralinderivate

Also Published As

Publication number Publication date
JPH06128228A (ja) 1994-05-10
US5318967A (en) 1994-06-07
DK0548664T3 (da) 1995-09-04
DE59202406D1 (de) 1995-07-06
IS3961A (is) 1993-06-21
CN1037510C (zh) 1998-02-25
GR3017256T3 (en) 1995-11-30
NO179325B (no) 1996-06-10
HUT68178A (en) 1995-05-29
CN1088576A (zh) 1994-06-29
BG97201A (bg) 1993-12-24
JPH07119215B2 (ja) 1995-12-20
BG61186B1 (bg) 1997-02-28
ATE123277T1 (de) 1995-06-15
AU661076B2 (en) 1995-07-13
EP0548664A1 (de) 1993-06-30
FI925774L (fi) 1993-06-21
HU9203956D0 (en) 1993-03-29
NO924829D0 (no) 1992-12-14
NO179325C (no) 1996-09-18
EP0548664B1 (de) 1995-05-31
FI925774A0 (fi) 1992-12-18
NO924829L (no) 1993-06-21
IL104080A0 (en) 1993-05-13
CZ381092A3 (en) 1993-09-15
CA2084442A1 (en) 1993-06-21
AU3018692A (en) 1993-06-24
ES2073847T3 (es) 1995-08-16
IL104080A (en) 1997-04-15
MY108026A (en) 1996-07-30
FI925774A7 (fi) 1993-06-21
TW239127B (enExample) 1995-01-21
US5318966A (en) 1994-06-07

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