HUT68178A - Indole derivatives and process for their preparation - Google Patents

Indole derivatives and process for their preparation

Info

Publication number
HUT68178A
HUT68178A HU9203956A HU9203956A HUT68178A HU T68178 A HUT68178 A HU T68178A HU 9203956 A HU9203956 A HU 9203956A HU 9203956 A HU9203956 A HU 9203956A HU T68178 A HUT68178 A HU T68178A
Authority
HU
Hungary
Prior art keywords
lower alkyl
denotes
cis
indole derivatives
amino
Prior art date
Application number
HU9203956A
Other languages
English (en)
Inventor
Rene Imhof
Hans Bruderer
Thierry Godel
Roland Jakob-Roetne
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HUT68178A publication Critical patent/HUT68178A/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/58[b]- or [c]-condensed
    • C07D209/60Naphtho [b] pyrroles; Hydrogenated naphtho [b] pyrroles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Psychiatry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HU9203956A 1991-12-20 1992-12-14 Indole derivatives and process for their preparation HUT68178A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH380691 1991-12-20
CH325492 1992-10-19

Publications (1)

Publication Number Publication Date
HUT68178A true HUT68178A (en) 1995-05-29

Family

ID=25692569

Family Applications (2)

Application Number Title Priority Date Filing Date
HU9203956A HU9203956D0 (en) 1991-12-20 1992-12-14 Method for producing indole derivatives
HU9203956A HUT68178A (en) 1991-12-20 1992-12-14 Indole derivatives and process for their preparation

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HU9203956A HU9203956D0 (en) 1991-12-20 1992-12-14 Method for producing indole derivatives

Country Status (21)

Country Link
US (2) US5318966A (hu)
EP (1) EP0548664B1 (hu)
JP (1) JPH07119215B2 (hu)
CN (1) CN1037510C (hu)
AT (1) ATE123277T1 (hu)
AU (1) AU661076B2 (hu)
BG (1) BG61186B1 (hu)
CA (1) CA2084442A1 (hu)
CZ (1) CZ381092A3 (hu)
DE (1) DE59202406D1 (hu)
DK (1) DK0548664T3 (hu)
ES (1) ES2073847T3 (hu)
FI (1) FI925774A (hu)
GR (1) GR3017256T3 (hu)
HU (2) HU9203956D0 (hu)
IL (1) IL104080A (hu)
IS (1) IS3961A (hu)
MY (1) MY108026A (hu)
NO (1) NO179325C (hu)
NZ (1) NZ245463A (hu)
TW (1) TW239127B (hu)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5486611A (en) * 1989-07-13 1996-01-23 The Upjohn Company Carboxamido-(1,2N)-carbocyclic-2-aminotetralin derivatives
WO1991000856A2 (en) * 1989-07-13 1991-01-24 The Upjohn Company (1,2n) and (3,2n)-carbocyclic-2-amino tetralin derivatives
ES2130135T3 (es) * 1990-01-11 1999-07-01 Upjohn Co Nuevos compuestos heterociclicos de 6,7,8,9-tetrahidro-3h-benz(e)indol con actividad terapeutica sobre el sistema nervioso central.
US5434170A (en) * 1993-12-23 1995-07-18 Andrulis Pharmaceuticals Corp. Method for treating neurocognitive disorders
WO1996003377A1 (en) * 1994-07-27 1996-02-08 Sankyo Company, Limited Heterocyclic compounds, useful as allosteric effectors at muscarinic receptors
US5859295A (en) * 1994-12-05 1999-01-12 University Of Kentucky Research Foundation Canavanine analogs and their use as chemotherapeutic agents
US5889006A (en) * 1995-02-23 1999-03-30 Schering Corporation Muscarinic antagonists
IL117149A0 (en) * 1995-02-23 1996-06-18 Schering Corp Muscarinic antagonists
GB9612153D0 (en) * 1996-06-11 1996-08-14 Smithkline Beecham Plc Compounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1277789A (en) * 1969-09-08 1972-06-14 Logeais Labor Jacques Improvements in or relating to new polycyclic pyrrole derivatives
JPS4930836B1 (hu) * 1971-07-22 1974-08-16
JPS4916862A (hu) * 1972-06-14 1974-02-14
SE8004002L (sv) * 1980-05-29 1981-11-30 Arvidsson Folke Lars Erik Terapeutiskt anvendbara tetralinderivat
SE8302361D0 (sv) * 1983-04-27 1983-04-27 Astra Laekemedel Ab New tricyclic amines
JP2785879B2 (ja) * 1989-05-31 1998-08-13 ジ・アップジョン・カンパニー 治療学的に有用な2―アミノテトラリン誘導体
WO1991000856A2 (en) * 1989-07-13 1991-01-24 The Upjohn Company (1,2n) and (3,2n)-carbocyclic-2-amino tetralin derivatives

Also Published As

Publication number Publication date
CN1088576A (zh) 1994-06-29
DK0548664T3 (da) 1995-09-04
ES2073847T3 (es) 1995-08-16
NO179325C (no) 1996-09-18
JPH07119215B2 (ja) 1995-12-20
NZ245463A (en) 1995-05-26
CN1037510C (zh) 1998-02-25
CZ381092A3 (en) 1993-09-15
AU661076B2 (en) 1995-07-13
FI925774A0 (fi) 1992-12-18
US5318967A (en) 1994-06-07
HU9203956D0 (en) 1993-03-29
EP0548664B1 (de) 1995-05-31
EP0548664A1 (de) 1993-06-30
AU3018692A (en) 1993-06-24
NO924829L (no) 1993-06-21
CA2084442A1 (en) 1993-06-21
IL104080A0 (en) 1993-05-13
DE59202406D1 (de) 1995-07-06
GR3017256T3 (en) 1995-11-30
IL104080A (en) 1997-04-15
ATE123277T1 (de) 1995-06-15
US5318966A (en) 1994-06-07
NO179325B (no) 1996-06-10
BG97201A (bg) 1993-12-24
JPH06128228A (ja) 1994-05-10
NO924829D0 (no) 1992-12-14
MY108026A (en) 1996-07-30
BG61186B1 (bg) 1997-02-28
IS3961A (is) 1993-06-21
TW239127B (hu) 1995-01-21
FI925774A (fi) 1993-06-21

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Legal Events

Date Code Title Description
DFD9 Temporary protection cancelled due to non-payment of fee