BG60680B1 - Р-заместени производни на 4-оксибутанамина, методи за получава- нето и приложението им - Google Patents
Р-заместени производни на 4-оксибутанамина, методи за получава- нето и приложението им Download PDFInfo
- Publication number
- BG60680B1 BG60680B1 BG96487A BG9648792A BG60680B1 BG 60680 B1 BG60680 B1 BG 60680B1 BG 96487 A BG96487 A BG 96487A BG 9648792 A BG9648792 A BG 9648792A BG 60680 B1 BG60680 B1 BG 60680B1
- Authority
- BG
- Bulgaria
- Prior art keywords
- general formula
- formula
- compounds
- radical
- compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR909012562A FR2668150B1 (fr) | 1990-10-17 | 1990-10-17 | Nouveaux derives du terbutylphenyl 1-amino 4-hydroxybutane, leurs procedes de preparation et les compositions pharmaceutiques en renfermant. |
| PCT/FR1991/000811 WO1992006977A1 (fr) | 1990-10-17 | 1991-10-17 | NOUVEAUX DERIVES p-SUBSTITUES DE PHENYL 4-OXYBUTANE AMINE, LEURS PROCEDES DE PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES EN RENFERMANT |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BG96487A BG96487A (bg) | 1993-12-24 |
| BG60680B1 true BG60680B1 (bg) | 1995-12-29 |
Family
ID=9401134
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG96487A BG60680B1 (bg) | 1990-10-17 | 1992-06-16 | Р-заместени производни на 4-оксибутанамина, методи за получава- нето и приложението им |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US5461059A (no) |
| EP (1) | EP0505543A1 (no) |
| JP (1) | JPH05503298A (no) |
| KR (1) | KR927003589A (no) |
| AP (1) | AP282A (no) |
| BG (1) | BG60680B1 (no) |
| BR (1) | BR9106188A (no) |
| CA (1) | CA2071911A1 (no) |
| CZ (1) | CZ182292A3 (no) |
| FI (1) | FI922773A0 (no) |
| FR (2) | FR2668150B1 (no) |
| HU (1) | HUT61297A (no) |
| IE (1) | IE913636A1 (no) |
| IL (1) | IL99776A0 (no) |
| MA (1) | MA22321A1 (no) |
| NO (1) | NO922358L (no) |
| NZ (1) | NZ240274A (no) |
| OA (1) | OA09835A (no) |
| PL (2) | PL169452B1 (no) |
| PT (1) | PT99266A (no) |
| RO (1) | RO108241B1 (no) |
| WO (1) | WO1992006977A1 (no) |
| ZA (1) | ZA918282B (no) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2048109B1 (es) * | 1992-07-20 | 1994-12-16 | Espanola Prod Quimicos | Procedimiento de preparacion de nuevos derivados piperidicos del bencimidazol. |
| WO1994027973A1 (fr) * | 1993-05-20 | 1994-12-08 | Kissei Pharmaceutical Co., Ltd. | Derive 1-(2-benzimidazolyl)-1,5-diazacyclooctane |
| ES2072193B1 (es) * | 1993-05-21 | 1996-02-16 | Espanola Prod Quimicos | Nuevos derivados del1-fenilmetil bencimidazol piperacinas. |
| US5691323A (en) * | 1995-05-12 | 1997-11-25 | Merck & Co., Inc. | Muscarine antagonists |
| FR2727865B1 (fr) * | 1994-12-08 | 1997-07-18 | Esteve Labor Dr | Utilisation des derives de 2-(4-(azolybutyl)-piperazinyl- (methyl))-benzimidazole et analogues ainsi que de leurs sels, pour la preparation de medicaments destines au traitement ou a la prophylaxie de l'asthme |
| WO1997036592A1 (en) * | 1996-04-03 | 1997-10-09 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
| AU6895801A (en) * | 2000-07-04 | 2002-01-14 | Novo Nordisk As | Heterocyclic compounds, which are inhibitors of the enzyme dpp-iv |
| EP1521584A1 (en) * | 2002-06-17 | 2005-04-13 | Glaxo Group Limited | Purine derivatives as liver x receptor agonists |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL130095C (no) * | 1962-08-31 | |||
| US3161645A (en) * | 1962-12-18 | 1964-12-15 | Res Lab Dr C Janssen N V | 1-(1-aroylpropyl-4-piperidyl)-2-benzimidazolinones and related compounds |
| US3491103A (en) * | 1963-12-19 | 1970-01-20 | Sandoz Ag | Certain 4h-benzo(4,5)cyclohepta-(1,2-b) thiophenes |
| US4219559A (en) * | 1979-01-10 | 1980-08-26 | Janssen Pharmaceutica N.V. | N-Heterocyclyl-4-piperidinamines |
| JPS5879983A (ja) * | 1981-11-06 | 1983-05-13 | Kanebo Ltd | 新規なベンズイミダゾ−ル誘導体、その製造法およびその医薬組成物 |
| US4695575A (en) * | 1984-11-13 | 1987-09-22 | Janssen Pharmaceutica, N.V. | 4-[(bicycle heterocyclyl)-methyl and -hetero]-piperidines |
| NZ223654A (en) * | 1987-03-09 | 1990-03-27 | Janssen Pharmaceutica Nv | 1-alkyl-substituted-benzimidazole-4-piperidinamines and pharmaceutical compositions |
| ATE141599T1 (de) * | 1988-04-28 | 1996-09-15 | Schering Corp | Kondensierte polyzyklische verbindungen, zusammenstellungen, verfahren zur herstellung und deren anwendung als paf-antagonistische, antihistaminische und/oder anti-inflammatorische agenzien |
| US4908372A (en) * | 1988-10-13 | 1990-03-13 | Merrell Dow Pharmaceuticals Inc. | Antihistaminic piperidinyl benzimidazoles |
| PH30434A (en) * | 1989-04-07 | 1997-05-09 | Janssen Pharmaceutica Nv | Hydroxyalkylfuranyl derivatives |
| US5217980A (en) * | 1990-07-19 | 1993-06-08 | Janssen Pharmaceutica N.V. | Oxazolyl and piperidinyl substituted benimidazolyl compounds |
-
1990
- 1990-10-17 FR FR909012562A patent/FR2668150B1/fr not_active Expired - Fee Related
-
1991
- 1991-10-11 FR FR919112515A patent/FR2670783B1/fr not_active Expired - Fee Related
- 1991-10-16 MA MA22603A patent/MA22321A1/fr unknown
- 1991-10-17 WO PCT/FR1991/000811 patent/WO1992006977A1/fr not_active Application Discontinuation
- 1991-10-17 PL PL91310562A patent/PL169452B1/pl unknown
- 1991-10-17 ZA ZA918282A patent/ZA918282B/xx unknown
- 1991-10-17 PL PL91295029A patent/PL169022B1/pl unknown
- 1991-10-17 NZ NZ240274A patent/NZ240274A/en unknown
- 1991-10-17 JP JP3517705A patent/JPH05503298A/ja active Pending
- 1991-10-17 KR KR1019920701452A patent/KR927003589A/ko not_active Application Discontinuation
- 1991-10-17 US US07/861,816 patent/US5461059A/en not_active Expired - Fee Related
- 1991-10-17 IE IE363691A patent/IE913636A1/en not_active Application Discontinuation
- 1991-10-17 EP EP91918443A patent/EP0505543A1/fr not_active Withdrawn
- 1991-10-17 BR BR919106188A patent/BR9106188A/pt not_active Application Discontinuation
- 1991-10-17 PT PT99266A patent/PT99266A/pt not_active Application Discontinuation
- 1991-10-17 IL IL99776A patent/IL99776A0/xx unknown
- 1991-10-17 CA CA002071911A patent/CA2071911A1/fr not_active Abandoned
- 1991-10-17 RO RO92-0818A patent/RO108241B1/ro unknown
- 1991-10-17 AP APAP/P/1991/000328A patent/AP282A/en active
- 1991-10-17 HU HU922176A patent/HUT61297A/hu unknown
-
1992
- 1992-06-15 CZ CS921822A patent/CZ182292A3/cs unknown
- 1992-06-16 NO NO92922358A patent/NO922358L/no unknown
- 1992-06-16 FI FI922773A patent/FI922773A0/fi not_active Application Discontinuation
- 1992-06-16 BG BG96487A patent/BG60680B1/bg unknown
- 1992-06-17 OA OA60229A patent/OA09835A/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AP9100328A0 (en) | 1991-10-31 |
| BR9106188A (pt) | 1993-03-16 |
| RO108241B1 (ro) | 1994-03-31 |
| JPH05503298A (ja) | 1993-06-03 |
| ZA918282B (en) | 1992-07-29 |
| WO1992006977A1 (fr) | 1992-04-30 |
| IL99776A0 (en) | 1992-08-18 |
| FI922773A (fi) | 1992-06-16 |
| FI922773A0 (fi) | 1992-06-16 |
| OA09835A (fr) | 1994-08-15 |
| PT99266A (pt) | 1992-08-31 |
| IE913636A1 (en) | 1992-04-22 |
| MA22321A1 (fr) | 1992-07-01 |
| NZ240274A (en) | 1995-07-26 |
| HU9202176D0 (en) | 1992-10-28 |
| KR927003589A (ko) | 1992-12-18 |
| FR2668150A1 (fr) | 1992-04-24 |
| FR2668150B1 (fr) | 1994-11-18 |
| FR2670783B1 (fr) | 1994-11-18 |
| NO922358D0 (no) | 1992-06-16 |
| BG96487A (bg) | 1993-12-24 |
| FR2670783A1 (fr) | 1992-06-26 |
| AP282A (en) | 1993-09-08 |
| US5461059A (en) | 1995-10-24 |
| CA2071911A1 (fr) | 1992-04-18 |
| PL169452B1 (pl) | 1996-07-31 |
| EP0505543A1 (fr) | 1992-09-30 |
| CZ182292A3 (en) | 1993-01-13 |
| HUT61297A (en) | 1992-12-28 |
| PL169022B1 (pl) | 1996-05-31 |
| NO922358L (no) | 1992-08-11 |
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