FR2727865B1 - Utilisation des derives de 2-(4-(azolybutyl)-piperazinyl- (methyl))-benzimidazole et analogues ainsi que de leurs sels, pour la preparation de medicaments destines au traitement ou a la prophylaxie de l'asthme - Google Patents

Utilisation des derives de 2-(4-(azolybutyl)-piperazinyl- (methyl))-benzimidazole et analogues ainsi que de leurs sels, pour la preparation de medicaments destines au traitement ou a la prophylaxie de l'asthme

Info

Publication number
FR2727865B1
FR2727865B1 FR9414766A FR9414766A FR2727865B1 FR 2727865 B1 FR2727865 B1 FR 2727865B1 FR 9414766 A FR9414766 A FR 9414766A FR 9414766 A FR9414766 A FR 9414766A FR 2727865 B1 FR2727865 B1 FR 2727865B1
Authority
FR
France
Prior art keywords
azolybutyl
piperazinyl
prophylaxis
asthma
salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9414766A
Other languages
English (en)
Other versions
FR2727865A1 (fr
Inventor
Altisent Maria Rosa Cuberes
Constansa Jordi Frigola
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Esteve Pharmaceuticals SA
Original Assignee
Laboratorios del Dr Esteve SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR9414766A priority Critical patent/FR2727865B1/fr
Application filed by Laboratorios del Dr Esteve SA filed Critical Laboratorios del Dr Esteve SA
Priority to JP8517338A priority patent/JPH09508923A/ja
Priority to PCT/EP1995/004884 priority patent/WO1996017609A1/fr
Priority to AU42611/96A priority patent/AU714581B2/en
Priority to CA002182904A priority patent/CA2182904A1/fr
Priority to EP95941089A priority patent/EP0741571A1/fr
Priority to ES09502465A priority patent/ES2105986B1/es
Priority to ZA9510435A priority patent/ZA9510435B/xx
Publication of FR2727865A1 publication Critical patent/FR2727865A1/fr
Priority to BR1100852-0A priority patent/BR1100852A/pt
Application granted granted Critical
Publication of FR2727865B1 publication Critical patent/FR2727865B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FR9414766A 1994-12-08 1994-12-08 Utilisation des derives de 2-(4-(azolybutyl)-piperazinyl- (methyl))-benzimidazole et analogues ainsi que de leurs sels, pour la preparation de medicaments destines au traitement ou a la prophylaxie de l'asthme Expired - Fee Related FR2727865B1 (fr)

Priority Applications (9)

Application Number Priority Date Filing Date Title
FR9414766A FR2727865B1 (fr) 1994-12-08 1994-12-08 Utilisation des derives de 2-(4-(azolybutyl)-piperazinyl- (methyl))-benzimidazole et analogues ainsi que de leurs sels, pour la preparation de medicaments destines au traitement ou a la prophylaxie de l'asthme
PCT/EP1995/004884 WO1996017609A1 (fr) 1994-12-08 1995-12-06 Utilisation des derives de 2-[4-(azolylbutyl)piperazinyl(methyl)] benzimidazole pour la preparation de medicaments destines au traitement ou a la prophylaxie de l'asthme
AU42611/96A AU714581B2 (en) 1994-12-08 1995-12-06 Use of 2-(4-(azolylbutyl)piperazinyl-(methyl)benzimidazole derivatives for preparing drugs for treating or preventing asthma
CA002182904A CA2182904A1 (fr) 1994-12-08 1995-12-06 Utilisation des derives de 2-[4-(azolylbutyl)piperazinyl(methyl)] benzimidazole pour la preparation de medicaments destines au traitement ou a la prophylaxie de l'asthme
JP8517338A JPH09508923A (ja) 1994-12-08 1995-12-06 喘息を治療又は予防する医薬を製造するための２−［４−（アゾリルブチル）ピペラジニル−（メチル）］ベンゾイミダゾール誘導体の使用
EP95941089A EP0741571A1 (fr) 1994-12-08 1995-12-06 Utilisation des derives de 2- 4-(azolylbutyl)piperazinyl(methyl)] benzimidazole pour la preparation de medicaments destines au traitement ou a la prophylaxie de l'asthme
ES09502465A ES2105986B1 (es) 1994-12-08 1995-12-07 Utilizacion de los derivados de 2-(4-(azolilbutil) piperacinil (metil)bencimidazol y analaagos, asi como de sus sales, para la preparacion de medicamentos destinados al tratamiento o a la profilaxis del asma.
ZA9510435A ZA9510435B (en) 1994-12-08 1995-12-08 Use of 2-(4-(azolylbutyl) piperazinyl (methyl)) benzimidazole derivatives and analogs as well as the salts thereof for the preparation of medicinal products intended for the treatment or prophylaxis of asthma
BR1100852-0A BR1100852A (pt) 1994-12-08 1997-05-12 Utilização dos compostos, e, composição farmacêutica

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9414766A FR2727865B1 (fr) 1994-12-08 1994-12-08 Utilisation des derives de 2-(4-(azolybutyl)-piperazinyl- (methyl))-benzimidazole et analogues ainsi que de leurs sels, pour la preparation de medicaments destines au traitement ou a la prophylaxie de l'asthme

Publications (2)

Publication Number Publication Date
FR2727865A1 FR2727865A1 (fr) 1996-06-14
FR2727865B1 true FR2727865B1 (fr) 1997-07-18

Family

ID=9469596

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9414766A Expired - Fee Related FR2727865B1 (fr) 1994-12-08 1994-12-08 Utilisation des derives de 2-(4-(azolybutyl)-piperazinyl- (methyl))-benzimidazole et analogues ainsi que de leurs sels, pour la preparation de medicaments destines au traitement ou a la prophylaxie de l'asthme

Country Status (9)

Country Link
EP (1) EP0741571A1 (fr)
JP (1) JPH09508923A (fr)
AU (1) AU714581B2 (fr)
BR (1) BR1100852A (fr)
CA (1) CA2182904A1 (fr)
ES (1) ES2105986B1 (fr)
FR (1) FR2727865B1 (fr)
WO (1) WO1996017609A1 (fr)
ZA (1) ZA9510435B (fr)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4200641A (en) * 1976-12-21 1980-04-29 Janssen Pharmaceutica, N.V. 1-[(Heterocyclyl)-alkyl]-4-diarylmethoxy piperidine derivatives
JPH0383924A (ja) * 1989-08-28 1991-04-09 Kanebo Ltd 経皮投与用組成物
FR2665161B1 (fr) * 1990-07-26 1992-11-27 Esteve Labor Dr Nouveaux derives de benzimidazole, leur preparation et leur application en tant que medicaments.
FR2668150B1 (fr) * 1990-10-17 1994-11-18 Theramex Nouveaux derives du terbutylphenyl 1-amino 4-hydroxybutane, leurs procedes de preparation et les compositions pharmaceutiques en renfermant.
FR2674856B1 (fr) * 1991-04-05 1993-07-30 Esteve Labor Dr Nouveaux antihistaminiques non sedatifs, derives de benzimidazole, leur procede de preparation et leur utilisation en tant que medicaments.

Also Published As

Publication number Publication date
EP0741571A1 (fr) 1996-11-13
AU714581B2 (en) 2000-01-06
ES2105986A1 (es) 1997-10-16
ES2105986B1 (es) 1998-07-01
ZA9510435B (en) 1996-06-14
JPH09508923A (ja) 1997-09-09
AU4261196A (en) 1996-06-26
WO1996017609A1 (fr) 1996-06-13
BR1100852A (pt) 1999-10-13
CA2182904A1 (fr) 1996-06-13
FR2727865A1 (fr) 1996-06-14

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