BG60500B2 - Естери на цефалоспорина - Google Patents

Естери на цефалоспорина Download PDF

Info

Publication number
BG60500B2
BG60500B2 BG98471A BG9847194A BG60500B2 BG 60500 B2 BG60500 B2 BG 60500B2 BG 98471 A BG98471 A BG 98471A BG 9847194 A BG9847194 A BG 9847194A BG 60500 B2 BG60500 B2 BG 60500B2
Authority
BG
Bulgaria
Prior art keywords
compound
formula
abq
reaction
acid
Prior art date
Application number
BG98471A
Other languages
Bulgarian (bg)
English (en)
Inventor
Tatsuo Nishimura
Yoshinobu Yoshimura
Mitsuo Numata
Original Assignee
Takeda Chemical Industries,Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP58099212A external-priority patent/JPS59225192A/ja
Priority claimed from JP59076834A external-priority patent/JPS60218394A/ja
Application filed by Takeda Chemical Industries,Ltd. filed Critical Takeda Chemical Industries,Ltd.
Publication of BG60500B2 publication Critical patent/BG60500B2/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BG98471A 1983-06-02 1994-02-14 Естери на цефалоспорина BG60500B2 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP58099212A JPS59225192A (ja) 1983-06-02 1983-06-02 セフアロスポリンエステル誘導体
JP59076834A JPS60218394A (ja) 1984-04-16 1984-04-16 セフアロスポリンエステル誘導体

Publications (1)

Publication Number Publication Date
BG60500B2 true BG60500B2 (bg) 1995-05-31

Family

ID=26417948

Family Applications (1)

Application Number Title Priority Date Filing Date
BG98471A BG60500B2 (bg) 1983-06-02 1994-02-14 Естери на цефалоспорина

Country Status (22)

Country Link
US (1) US5120841A (es)
EP (1) EP0128029B1 (es)
KR (1) KR910008350B1 (es)
AR (2) AR240825A1 (es)
AT (1) ATE40691T1 (es)
AU (1) AU566096B2 (es)
BG (1) BG60500B2 (es)
CA (1) CA1216285A (es)
DE (1) DE3476662D1 (es)
DK (1) DK273784A (es)
ES (4) ES8506577A1 (es)
FI (1) FI75574C (es)
GR (1) GR79941B (es)
HK (1) HK9492A (es)
HU (1) HU192028B (es)
IN (1) IN158586B (es)
MY (1) MY101993A (es)
NO (1) NO162470C (es)
NZ (1) NZ208281A (es)
PH (1) PH19575A (es)
PT (1) PT78684B (es)
SG (1) SG392G (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0010475D0 (en) * 2000-04-28 2000-06-14 Biochemie Gmbh Organic compounds
CN101993449B (zh) * 2009-08-13 2012-10-31 丽珠医药集团股份有限公司 高纯度头孢替安酯及其二盐酸盐的制备方法
CN102241692A (zh) * 2010-05-14 2011-11-16 广州白云山制药股份有限公司广州白云山制药总厂 溶媒结晶法制备头孢替安酯盐酸盐的方法
CN101948476B (zh) * 2010-09-19 2012-07-25 苏州致君万庆药业有限公司 一种头孢替安酯盐酸盐的制备方法
CN102424687A (zh) * 2011-11-01 2012-04-25 湖南方盛制药股份有限公司 盐酸头孢替安酯的制备方法
CN102898441A (zh) * 2012-10-11 2013-01-30 南通康鑫药业有限公司 一种头孢替安的合成方法
CN103012436B (zh) * 2012-12-04 2015-07-01 山东鑫泉医药有限公司 头孢替安盐酸盐的制备方法
CN104031068A (zh) * 2014-06-11 2014-09-10 济南诚汇双达化工有限公司 一锅法制备盐酸头孢替安酯的方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1425933A (en) * 1972-03-13 1976-02-25 Astra Laekemedel Ab Cephalosporins
NZ176206A (en) * 1973-12-25 1978-03-06 Takeda Chemical Industries Ltd Cephalosporins
US4189479A (en) * 1977-12-22 1980-02-19 Takeda Chemical Industries, Ltd. Cephalosporin esters
DE2805794A1 (de) * 1978-02-11 1979-08-16 Hoechst Ag Vorrichtung zum biologischen reinigen von abwasser
JPS6042766B2 (ja) * 1978-12-09 1985-09-25 日本化薬株式会社 基剤
JPS5759894A (en) * 1980-09-30 1982-04-10 Sankyo Co Ltd Cephalosporin for oral administration
JPS5777690A (en) * 1980-10-31 1982-05-15 Takeda Chem Ind Ltd Cephalosporin derivative
JPS58189186A (ja) * 1982-04-30 1983-11-04 Takeda Chem Ind Ltd セフアロスポリン誘導体
JPS5989691A (ja) * 1982-11-15 1984-05-23 Takeda Chem Ind Ltd セフアロスポリンエステル
US4616008A (en) * 1984-05-02 1986-10-07 Takeda Chemical Industries, Ltd. Antibacterial solid composition for oral administration

Also Published As

Publication number Publication date
AU566096B2 (en) 1987-10-08
HUT34505A (en) 1985-03-28
DE3476662D1 (en) 1989-03-16
CA1216285A (en) 1987-01-06
PH19575A (en) 1986-05-26
FI842210A (fi) 1984-12-03
EP0128029A2 (en) 1984-12-12
HK9492A (en) 1992-01-31
PT78684B (en) 1986-10-21
MY101993A (en) 1992-02-29
NO162470C (no) 1990-01-10
FI842210A0 (fi) 1984-06-01
KR910008350B1 (ko) 1991-10-12
EP0128029B1 (en) 1989-02-08
IN158586B (es) 1986-12-13
ES556838A0 (es) 1988-01-01
ES8703480A1 (es) 1987-02-16
AR245132A1 (es) 1993-12-30
GR79941B (es) 1984-10-31
ES549761A0 (es) 1987-02-16
ES8801287A1 (es) 1988-01-01
ES533051A0 (es) 1985-08-01
DK273784D0 (da) 1984-06-01
HU192028B (en) 1987-04-28
AU2874884A (en) 1984-12-06
AR240825A1 (es) 1991-02-28
SG392G (en) 1992-03-20
EP0128029A3 (en) 1985-12-18
NZ208281A (en) 1986-11-12
KR850000455A (ko) 1985-02-27
NO162470B (no) 1989-09-25
AR240825A2 (es) 1991-02-28
ATE40691T1 (de) 1989-02-15
FI75574C (fi) 1988-07-11
DK273784A (da) 1984-12-03
ES540839A0 (es) 1986-05-16
ES8607317A1 (es) 1986-05-16
NO842224L (no) 1984-12-03
ES8506577A1 (es) 1985-08-01
FI75574B (fi) 1988-03-31
US5120841A (en) 1992-06-09
PT78684A (en) 1984-07-01

Similar Documents

Publication Publication Date Title
FI66618C (fi) Foerfarande foer framstaellning av terapeutiskt verkande 7-(2-(2-aminotiazol-4-yl)-2-(syn)-metoxi-iminoacetamido-cefalosporinderivat
US7405294B2 (en) Intermediate cefdinir salts
NO165027B (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive propenyl-cefalosporinforbindelser.
EP0771803A1 (en) Pyrazolo(1,5-a)pyrimidinium substituted cephem derivatives, their preparation and their use as antimicrobial agents
JPS6153359B2 (es)
US5081116A (en) Cephalosporin derivatives
EP0329008B1 (de) Cephalosporinderivative und Verfahren zu ihrer Herstellung
EP0264091B1 (en) 3-propenylcephem derivative, preparation thereof, chemical intermediates therein, pharmaceutical composition and use
BG60500B2 (bg) Естери на цефалоспорина
EP0093548B1 (en) Cephalosporin derivatives
HU221429B (en) 7-acyl-3-(substituted carbamoyloxy)-methyl-cef-3-em-4-carboxylic acid derivatives, process for their preparation and pharmaceutical compositions comprising such compounds
US4104469A (en) 7-(Syn-α-alkoxy-iminofuryl)acetamido-3-(2-methyl-2,3-dihydro-s-triazolo[4,3-b]pyridazin-3-on-6-ylthiomethyl)-3-cephem-4-carboxylic acids
US4103008A (en) 7[2(2,3 Dioxopiperazin-1-yl-carbonylamino)substituted 2 phenylacetamido]-3-2'-thiadiazolyl cephalosporanic acid derivatives
US4117126A (en) 7-(α-(4-Hydroxy-1,5-naphthyridine-3-carbonamido)-α-phenylacetamido) cephalosporin derivatives
US3850916A (en) 7-amino-3-(s-(1,2,3-triazole-5-yl)-thiomethyl)-3-cephem-4-carboxylic acid and salts thereof
CA1215355A (en) Cephalosporin esters, their production and use
RU2201933C2 (ru) Антибактериальные замещенные 7-ациламино-3-(метилгидразоно)метилцефалоспорины, способ их получения, фармацевтические композиции на их основе, промежуточные соединения и способ лечения заболеваний, вызванных микроорганизмами
US5872249A (en) 3-ammoniopropenyl cephalosporin compounds as antibacterial agents and process for preparing the same
US4619925A (en) 3-Propenyl cephalosporin derivatives
US4179502A (en) 7[2-Hydroxyiminoacetamido]cephalosporins
US4797395A (en) 1-Acyloxyalkyl esters of cephalosporin
EP0081971A2 (en) Novel cephalosporin compound and process for preparing the same
US4755598A (en) 1'-(substituted)ethyl-7β-[2-(2-aminothiazol-4-yl)acetamido]-3-[[[1-(2-dimethylaminoethyl)-1H-tetrazol-5-yl]thio]methyl]ceph-3-em-4-carboxylate derivatives having antibacterial utility
EP0109294A2 (en) Cephalosporin esters
Applegate et al. DIASTEREOMERIC 7-UREIDOACETYL CEPHALOSPORINS. II 7β-[[[(AMINOCARBONYL) AMINO]-2-THIENYLACETYL] AMINO]-7-METHOXY-3-[[(1-METHYL-1H-TETRAZOL-5-YL) THIO] METHYL]-8-OXO-5-THIA-1-AZABICYCLO [4.2. 0] OCT-2-ENE-2-CARBOXYLIC ACID