BG44204A3 - Method for preparing of 2- oxyindol derivatives - Google Patents
Method for preparing of 2- oxyindol derivativesInfo
- Publication number
- BG44204A3 BG44204A3 BG072170A BG7217085A BG44204A3 BG 44204 A3 BG44204 A3 BG 44204A3 BG 072170 A BG072170 A BG 072170A BG 7217085 A BG7217085 A BG 7217085A BG 44204 A3 BG44204 A3 BG 44204A3
- Authority
- BG
- Bulgaria
- Prior art keywords
- preparing
- oxyindol
- derivatives
- oxyindoles
- compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229940035676 analgesics Drugs 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 229940121363 anti-inflammatory agent Drugs 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/38—Oxygen atoms in positions 2 and 3, e.g. isatin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57790384A | 1984-02-07 | 1984-02-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG44204A3 true BG44204A3 (en) | 1988-10-14 |
Family
ID=24310612
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG072172A BG43865A3 (en) | 1984-02-07 | 1985-02-06 | Method for preparing of 1, 3- disubstituted 2- oxyindols |
| BG068717A BG40963A3 (en) | 1984-02-07 | 1985-02-06 | Method for preparing 1, 3- disubstituted 2- oxyindols |
| BG072170A BG44204A3 (en) | 1984-02-07 | 1985-02-06 | Method for preparing of 2- oxyindol derivatives |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG072172A BG43865A3 (en) | 1984-02-07 | 1985-02-06 | Method for preparing of 1, 3- disubstituted 2- oxyindols |
| BG068717A BG40963A3 (en) | 1984-02-07 | 1985-02-06 | Method for preparing 1, 3- disubstituted 2- oxyindols |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4658037A (enExample) |
| JP (1) | JPS60248669A (enExample) |
| KR (2) | KR880000433B1 (enExample) |
| BG (3) | BG43865A3 (enExample) |
| CS (1) | CS252480B2 (enExample) |
| DD (2) | DD234417A5 (enExample) |
| HU (1) | HU194166B (enExample) |
| IN (1) | IN163263B (enExample) |
| MW (1) | MW185A1 (enExample) |
| PL (3) | PL145230B1 (enExample) |
| RO (2) | RO93218B (enExample) |
| YU (3) | YU43866B (enExample) |
| ZA (1) | ZA85888B (enExample) |
| ZM (1) | ZM785A1 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4721712A (en) * | 1984-06-12 | 1988-01-26 | Pfizer Inc. | 1,3-disubstituted 2-oxindoles as analgesic and anti-inflammatory agents |
| US4808601A (en) * | 1984-09-19 | 1989-02-28 | Pfizer Inc. | Analgesic and antiinflammatory 1,3-diacyl-2-oxindole compounds |
| US4752609A (en) * | 1985-06-20 | 1988-06-21 | Pfizer Inc. | Analgesic and antiinflammatory 1,3-diacyl-2-oxindole compounds |
| HU215112B (hu) * | 1989-01-10 | 1998-12-28 | Pfizer Inc. | Eljárás gyulladáscsökkentő 1-heteroaril-3-acil-2-oxindol-származékok előállítására |
| US5086186A (en) * | 1989-05-25 | 1992-02-04 | Pfizer Inc. | N-trichloroacetyl-2-oxindole-1-carboxamides |
| US4952703A (en) * | 1989-05-25 | 1990-08-28 | Pfizer Inc. | Intermediates for making 2-oxindole-1-carboxamides |
| US5744101A (en) | 1989-06-07 | 1998-04-28 | Affymax Technologies N.V. | Photolabile nucleoside protecting groups |
| US6955915B2 (en) | 1989-06-07 | 2005-10-18 | Affymetrix, Inc. | Apparatus comprising polymers |
| US6919211B1 (en) | 1989-06-07 | 2005-07-19 | Affymetrix, Inc. | Polypeptide arrays |
| US5298522A (en) * | 1993-01-22 | 1994-03-29 | Pfizer Inc. | 6-chloro-5-fluoro-3-(2-thenoyl)-2-oxindole-1-carboxamide as an analgesic and anti-inflammatory agent while maintaining a normal urine protein/creatinine ratio |
| WO1994018194A1 (en) * | 1993-02-09 | 1994-08-18 | Pfizer Inc. | Oxindole 1-[n-(alkoxycarbonyl)]carboxamides and 1-(n-carboxamido)carboxamides as intiinflammatory agents |
| EP2147679B1 (en) | 2001-07-25 | 2014-06-25 | Raptor Pharmaceutical, Inc. | Compositions for blood-brain barrier transport |
| EP2392258B1 (en) | 2005-04-28 | 2014-10-08 | Proteus Digital Health, Inc. | Pharma-informatics system |
| CN101594878A (zh) | 2006-09-18 | 2009-12-02 | 雷普特药品公司 | 通过给予受体相关蛋白（rap）-缀合物对肝病症的治疗 |
| JP2009040790A (ja) * | 2008-08-29 | 2009-02-26 | Ube Ind Ltd | ５−フルオロオキシインドールの製造法 |
| PL3395372T3 (pl) | 2009-02-20 | 2022-07-25 | EnhanX Biopharm Inc. | Układ do dostarczania leków na bazie glutationu |
| CN102458374A (zh) | 2009-05-06 | 2012-05-16 | 实验室护肤股份有限公司 | 包含活性剂-磷酸钙颗粒复合物的皮肤递送组合物及其使用方法 |
| US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
| CN103570604B (zh) * | 2012-07-21 | 2015-10-07 | 重庆圣华曦药业股份有限公司 | 齐拉西酮中间体的合成方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3462450A (en) * | 1966-06-29 | 1969-08-19 | Merck & Co Inc | Chemical compounds |
| GB1158532A (en) * | 1967-01-05 | 1969-07-16 | Centre Nat Rech Scient | 2-Oxoindoline-3-Carboxylic Acids and Esters thereof |
| US3631177A (en) * | 1967-04-18 | 1971-12-28 | Smith Kline French Lab | 3-phenacyl-2-oxoindolines |
| US3519592A (en) * | 1967-04-18 | 1970-07-07 | Smithkline Corp | Indole compounds |
| BE714717A (enExample) * | 1967-05-12 | 1968-09-30 | ||
| FR7337M (enExample) * | 1968-01-11 | 1969-10-13 | ||
| BE756447A (fr) * | 1969-10-15 | 1971-03-22 | Pfizer | Oxindolecarboxamides |
| US3749731A (en) * | 1971-07-08 | 1973-07-31 | Warner Lambert Co | 2-oxo-n-(2-thiazolyl)-3-indoline-carboxamide |
| US3975531A (en) * | 1973-10-02 | 1976-08-17 | A. H. Robins Company, Incorporated | 4-(5- And 7-)benzoylindolin-2-ones and pharmaceutical uses thereof |
| US4221716A (en) * | 1979-02-16 | 1980-09-09 | A. H. Robins Company, Inc. | Intermediate and process for the preparation of 7-acylindolin-2-ones |
-
1985
- 1985-01-22 IN IN42/DEL/85A patent/IN163263B/en unknown
- 1985-02-04 RO RO121802A patent/RO93218B/ro unknown
- 1985-02-04 RO RO85117533A patent/RO90621A2/ro unknown
- 1985-02-05 ZM ZM7/85A patent/ZM785A1/xx unknown
- 1985-02-05 MW MW1/85A patent/MW185A1/xx unknown
- 1985-02-05 CS CS85785A patent/CS252480B2/cs unknown
- 1985-02-05 KR KR1019850000714A patent/KR880000433B1/ko not_active Expired
- 1985-02-06 DD DD85273087A patent/DD234417A5/de not_active IP Right Cessation
- 1985-02-06 ZA ZA85888A patent/ZA85888B/xx unknown
- 1985-02-06 BG BG072172A patent/BG43865A3/xx unknown
- 1985-02-06 JP JP60020163A patent/JPS60248669A/ja active Granted
- 1985-02-06 BG BG068717A patent/BG40963A3/xx unknown
- 1985-02-06 BG BG072170A patent/BG44204A3/xx unknown
- 1985-02-06 HU HU854686A patent/HU194166B/hu unknown
- 1985-02-06 YU YU180/85A patent/YU43866B/xx unknown
- 1985-02-07 PL PL1985255466A patent/PL145230B1/pl unknown
- 1985-02-07 PL PL1985251869A patent/PL145196B1/pl unknown
- 1985-02-07 PL PL1985255465A patent/PL145310B1/pl unknown
- 1985-12-30 US US06/814,719 patent/US4658037A/en not_active Expired - Lifetime
-
1986
- 1986-04-01 DD DD86288635A patent/DD244133A5/de not_active IP Right Cessation
-
1987
- 1987-04-10 KR KR1019870003430A patent/KR880000434B1/ko not_active Expired
- 1987-07-09 YU YU129087A patent/YU46320B/sh unknown
- 1987-10-30 YU YU1981/87A patent/YU44062B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL145310B1 (en) | 1988-09-30 |
| JPS60248669A (ja) | 1985-12-09 |
| CS78585A2 (en) | 1987-01-15 |
| ZM785A1 (en) | 1985-08-22 |
| PL251869A1 (en) | 1985-12-17 |
| RO90621A2 (ro) | 1986-12-10 |
| KR880000434B1 (ko) | 1988-03-24 |
| US4658037A (en) | 1987-04-14 |
| YU129087A (en) | 1988-02-29 |
| HU194166B (en) | 1988-01-28 |
| RO93218A (ro) | 1987-12-31 |
| KR880000433B1 (ko) | 1988-03-24 |
| JPH0413340B2 (enExample) | 1992-03-09 |
| DD244133A5 (de) | 1987-03-25 |
| ZA85888B (en) | 1986-09-24 |
| YU46320B (sh) | 1993-05-28 |
| CS252480B2 (en) | 1987-09-17 |
| DD234417A5 (de) | 1986-04-02 |
| PL255465A1 (en) | 1986-07-15 |
| YU198187A (en) | 1988-10-31 |
| YU43866B (en) | 1989-12-31 |
| PL145230B1 (en) | 1988-08-31 |
| IN163263B (enExample) | 1988-08-27 |
| YU44062B (en) | 1990-02-28 |
| BG40963A3 (en) | 1987-03-14 |
| MW185A1 (en) | 1986-04-09 |
| YU18085A (en) | 1988-04-30 |
| KR850005824A (ko) | 1985-09-26 |
| RO93218B (ro) | 1988-01-01 |
| BG43865A3 (en) | 1988-08-15 |
| PL145196B1 (en) | 1988-08-31 |
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