BG40963A3 - Method for preparing 1, 3- disubstituted 2- oxyindols - Google Patents
Method for preparing 1, 3- disubstituted 2- oxyindolsInfo
- Publication number
- BG40963A3 BG40963A3 BG8568717A BG6871785A BG40963A3 BG 40963 A3 BG40963 A3 BG 40963A3 BG 8568717 A BG8568717 A BG 8568717A BG 6871785 A BG6871785 A BG 6871785A BG 40963 A3 BG40963 A3 BG 40963A3
- Authority
- BG
- Bulgaria
- Prior art keywords
- oxyindols
- disubstituted
- preparing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/38—Oxygen atoms in positions 2 and 3, e.g. isatin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57790384A | 1984-02-07 | 1984-02-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG40963A3 true BG40963A3 (en) | 1987-03-14 |
Family
ID=24310612
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG8568717A BG40963A3 (en) | 1984-02-07 | 1985-02-06 | Method for preparing 1, 3- disubstituted 2- oxyindols |
| BG8572170A BG44204A3 (en) | 1984-02-07 | 1985-02-06 | Method for preparing of 2- oxyindol derivatives |
| BG8572172A BG43865A3 (en) | 1984-02-07 | 1985-02-06 | Method for preparing of 1, 3- disubstituted 2- oxyindols |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG8572170A BG44204A3 (en) | 1984-02-07 | 1985-02-06 | Method for preparing of 2- oxyindol derivatives |
| BG8572172A BG43865A3 (en) | 1984-02-07 | 1985-02-06 | Method for preparing of 1, 3- disubstituted 2- oxyindols |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4658037A (xx) |
| JP (1) | JPS60248669A (xx) |
| KR (2) | KR880000433B1 (xx) |
| BG (3) | BG40963A3 (xx) |
| CS (1) | CS252480B2 (xx) |
| DD (2) | DD234417A5 (xx) |
| HU (1) | HU194166B (xx) |
| IN (1) | IN163263B (xx) |
| MW (1) | MW185A1 (xx) |
| PL (3) | PL145310B1 (xx) |
| RO (2) | RO93218B (xx) |
| YU (3) | YU43866B (xx) |
| ZA (1) | ZA85888B (xx) |
| ZM (1) | ZM785A1 (xx) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4721712A (en) * | 1984-06-12 | 1988-01-26 | Pfizer Inc. | 1,3-disubstituted 2-oxindoles as analgesic and anti-inflammatory agents |
| US4808601A (en) * | 1984-09-19 | 1989-02-28 | Pfizer Inc. | Analgesic and antiinflammatory 1,3-diacyl-2-oxindole compounds |
| US4752609A (en) * | 1985-06-20 | 1988-06-21 | Pfizer Inc. | Analgesic and antiinflammatory 1,3-diacyl-2-oxindole compounds |
| WO1990008145A1 (en) * | 1989-01-10 | 1990-07-26 | Pfizer Inc. | Anti-inflammatory 1-heteroaryl-3-acyl-2-oxindoles |
| US4952703A (en) * | 1989-05-25 | 1990-08-28 | Pfizer Inc. | Intermediates for making 2-oxindole-1-carboxamides |
| US5086186A (en) * | 1989-05-25 | 1992-02-04 | Pfizer Inc. | N-trichloroacetyl-2-oxindole-1-carboxamides |
| US5298522A (en) * | 1993-01-22 | 1994-03-29 | Pfizer Inc. | 6-chloro-5-fluoro-3-(2-thenoyl)-2-oxindole-1-carboxamide as an analgesic and anti-inflammatory agent while maintaining a normal urine protein/creatinine ratio |
| CA2155664C (en) * | 1993-02-09 | 1999-06-15 | Ralph P. Robinson | Oxindole 1-[n-(alkoxycarbonyl)]carboxamides and 1-(n-carboxamido)carboxamides as antiinflammatory agents |
| EP1554572B1 (en) | 2001-07-25 | 2009-10-14 | Raptor Pharmaceutical Inc. | Compositions and methods for modulating blood-brain barrier transport |
| EP3827747A1 (en) | 2005-04-28 | 2021-06-02 | Otsuka Pharmaceutical Co., Ltd. | Pharma-informatics system |
| EP2063905B1 (en) | 2006-09-18 | 2014-07-30 | Raptor Pharmaceutical Inc | Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates |
| JP2009040790A (ja) * | 2008-08-29 | 2009-02-26 | Ube Ind Ltd | ５−フルオロオキシインドールの製造法 |
| NZ616673A (en) | 2009-02-20 | 2014-08-29 | To Bbb Holding B V | Glutathione-based drug delivery system |
| ES2942923T3 (es) | 2009-05-06 | 2023-06-07 | Laboratory Skin Care Inc | Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas |
| US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
| CN103570604B (zh) * | 2012-07-21 | 2015-10-07 | 重庆圣华曦药业股份有限公司 | 齐拉西酮中间体的合成方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3462450A (en) * | 1966-06-29 | 1969-08-19 | Merck & Co Inc | Chemical compounds |
| GB1158532A (en) * | 1967-01-05 | 1969-07-16 | Centre Nat Rech Scient | 2-Oxoindoline-3-Carboxylic Acids and Esters thereof |
| US3519592A (en) * | 1967-04-18 | 1970-07-07 | Smithkline Corp | Indole compounds |
| US3631177A (en) * | 1967-04-18 | 1971-12-28 | Smith Kline French Lab | 3-phenacyl-2-oxoindolines |
| BE714717A (xx) * | 1967-05-12 | 1968-09-30 | ||
| FR7337M (xx) * | 1968-01-11 | 1969-10-13 | ||
| BE756447A (fr) * | 1969-10-15 | 1971-03-22 | Pfizer | Oxindolecarboxamides |
| US3749731A (en) * | 1971-07-08 | 1973-07-31 | Warner Lambert Co | 2-oxo-n-(2-thiazolyl)-3-indoline-carboxamide |
| US3975531A (en) * | 1973-10-02 | 1976-08-17 | A. H. Robins Company, Incorporated | 4-(5- And 7-)benzoylindolin-2-ones and pharmaceutical uses thereof |
| US4221716A (en) * | 1979-02-16 | 1980-09-09 | A. H. Robins Company, Inc. | Intermediate and process for the preparation of 7-acylindolin-2-ones |
-
1985
- 1985-01-22 IN IN42/DEL/85A patent/IN163263B/en unknown
- 1985-02-04 RO RO121802A patent/RO93218B/ro unknown
- 1985-02-04 RO RO85117533A patent/RO90621A2/ro unknown
- 1985-02-05 MW MW1/85A patent/MW185A1/xx unknown
- 1985-02-05 ZM ZM7/85A patent/ZM785A1/xx unknown
- 1985-02-05 KR KR1019850000714A patent/KR880000433B1/ko not_active IP Right Cessation
- 1985-02-05 CS CS85785A patent/CS252480B2/cs unknown
- 1985-02-06 BG BG8568717A patent/BG40963A3/xx unknown
- 1985-02-06 HU HU854686A patent/HU194166B/hu unknown
- 1985-02-06 YU YU180/85A patent/YU43866B/xx unknown
- 1985-02-06 BG BG8572170A patent/BG44204A3/xx unknown
- 1985-02-06 JP JP60020163A patent/JPS60248669A/ja active Granted
- 1985-02-06 ZA ZA85888A patent/ZA85888B/xx unknown
- 1985-02-06 DD DD85273087A patent/DD234417A5/de not_active IP Right Cessation
- 1985-02-06 BG BG8572172A patent/BG43865A3/xx unknown
- 1985-02-07 PL PL1985255465A patent/PL145310B1/pl unknown
- 1985-02-07 PL PL1985255466A patent/PL145230B1/pl unknown
- 1985-02-07 PL PL1985251869A patent/PL145196B1/pl unknown
- 1985-12-30 US US06/814,719 patent/US4658037A/en not_active Expired - Lifetime
-
1986
- 1986-04-01 DD DD86288635A patent/DD244133A5/de not_active IP Right Cessation
-
1987
- 1987-04-10 KR KR1019870003430A patent/KR880000434B1/ko not_active IP Right Cessation
- 1987-07-09 YU YU129087A patent/YU46320B/sh unknown
- 1987-10-30 YU YU1981/87A patent/YU44062B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HU194166B (en) | 1988-01-28 |
| YU129087A (en) | 1988-02-29 |
| PL255465A1 (en) | 1986-07-15 |
| CS78585A2 (en) | 1987-01-15 |
| JPS60248669A (ja) | 1985-12-09 |
| PL145196B1 (en) | 1988-08-31 |
| BG44204A3 (en) | 1988-10-14 |
| PL251869A1 (en) | 1985-12-17 |
| DD244133A5 (de) | 1987-03-25 |
| ZM785A1 (en) | 1985-08-22 |
| US4658037A (en) | 1987-04-14 |
| YU43866B (en) | 1989-12-31 |
| YU46320B (sh) | 1993-05-28 |
| BG43865A3 (en) | 1988-08-15 |
| MW185A1 (en) | 1986-04-09 |
| DD234417A5 (de) | 1986-04-02 |
| KR880000434B1 (ko) | 1988-03-24 |
| KR850005824A (ko) | 1985-09-26 |
| RO93218B (ro) | 1988-01-01 |
| YU18085A (en) | 1988-04-30 |
| ZA85888B (en) | 1986-09-24 |
| YU44062B (en) | 1990-02-28 |
| RO93218A (ro) | 1987-12-31 |
| JPH0413340B2 (xx) | 1992-03-09 |
| CS252480B2 (en) | 1987-09-17 |
| RO90621A2 (ro) | 1986-12-10 |
| YU198187A (en) | 1988-10-31 |
| KR880000433B1 (ko) | 1988-03-24 |
| IN163263B (xx) | 1988-08-27 |
| PL145230B1 (en) | 1988-08-31 |
| PL145310B1 (en) | 1988-09-30 |
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