HUT37754A - Process for preparing n,3-disubstituted 2-oxindole-1-carboxamide derivatives - Google Patents

Process for preparing n,3-disubstituted 2-oxindole-1-carboxamide derivatives

Info

Publication number
HUT37754A
HUT37754A HU851693A HU169385A HUT37754A HU T37754 A HUT37754 A HU T37754A HU 851693 A HU851693 A HU 851693A HU 169385 A HU169385 A HU 169385A HU T37754 A HUT37754 A HU T37754A
Authority
HU
Hungary
Prior art keywords
oxindole
disubstituted
preparing
carboxamide derivatives
carboxamide
Prior art date
Application number
HU851693A
Other languages
Hungarian (hu)
Other versions
HU196057B (en
Inventor
Saul B Kadin
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of HUT37754A publication Critical patent/HUT37754A/en
Publication of HU196057B publication Critical patent/HU196057B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/60—Naphtho [b] pyrroles; Hydrogenated naphtho [b] pyrroles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/70—[b]- or [c]-condensed containing carbocyclic rings other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HU851693A 1984-05-04 1985-05-31 Process for producing n,3-disubstituted 2-oxindolo-1-carboxamide derivatives HU196057B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US60735684A 1984-05-04 1984-05-04

Publications (2)

Publication Number Publication Date
HUT37754A true HUT37754A (en) 1986-02-28
HU196057B HU196057B (en) 1988-09-28

Family

ID=24431933

Family Applications (1)

Application Number Title Priority Date Filing Date
HU851693A HU196057B (en) 1984-05-04 1985-05-31 Process for producing n,3-disubstituted 2-oxindolo-1-carboxamide derivatives

Country Status (25)

Country Link
JP (1) JPS60243068A (en)
KR (1) KR870000497B1 (en)
AR (1) AR241159A1 (en)
BG (2) BG60208B2 (en)
CS (1) CS252828B2 (en)
DD (1) DD232916A5 (en)
EG (1) EG17193A (en)
ES (2) ES8609248A1 (en)
FI (1) FI80016C (en)
HU (1) HU196057B (en)
IE (1) IE851103L (en)
IN (1) IN161509B (en)
MA (1) MA20424A1 (en)
MW (1) MW1685A1 (en)
MX (1) MX5839A (en)
NO (1) NO163132C (en)
OA (1) OA08098A (en)
PL (2) PL147508B1 (en)
PT (1) PT80375B (en)
RO (2) RO91141B (en)
RU (1) RU2017729C1 (en)
SU (1) SU1468413A3 (en)
YU (1) YU44998B (en)
ZA (1) ZA853324B (en)
ZW (1) ZW7885A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5047554A (en) * 1989-04-18 1991-09-10 Pfizer Inc. 3-substituted-2-oxindole derivatives
IL95880A (en) * 1989-10-13 1995-12-31 Pfizer Use of 3-substituted-2-oxindole derivatives for the preparation of a pharmaceutical preparation for inhibiting interleukin-1 biosynthesis

Also Published As

Publication number Publication date
RO91141A (en) 1987-06-30
HU196057B (en) 1988-09-28
ES542813A0 (en) 1986-07-16
FI80016C (en) 1990-04-10
RO94455B (en) 1988-07-01
MW1685A1 (en) 1986-09-10
SU1468413A3 (en) 1989-03-23
FI80016B (en) 1989-12-29
FI851756A0 (en) 1985-05-03
PL253203A1 (en) 1986-06-17
CS252828B2 (en) 1987-10-15
PT80375B (en) 1987-09-30
NO851774L (en) 1985-11-05
RU2017729C1 (en) 1994-08-15
OA08098A (en) 1987-03-31
FI851756L (en) 1985-11-05
KR870000497B1 (en) 1987-03-12
AR241159A2 (en) 1991-12-30
CS320285A2 (en) 1987-03-12
YU73085A (en) 1988-04-30
RO94455A (en) 1988-06-30
BG60207B2 (en) 1993-12-30
PL145416B1 (en) 1988-09-30
ES8707182A1 (en) 1987-07-16
IN161509B (en) 1987-12-19
JPS60243068A (en) 1985-12-03
PL257892A1 (en) 1986-10-07
RO91141B (en) 1987-07-03
BG60208B2 (en) 1993-12-30
AR241159A1 (en) 1991-12-30
YU44998B (en) 1991-06-30
NO163132B (en) 1990-01-02
PL147508B1 (en) 1989-06-30
ZA853324B (en) 1986-12-30
JPH0335315B2 (en) 1991-05-27
PT80375A (en) 1985-05-01
MX5839A (en) 1993-11-01
IE851103L (en) 1985-11-04
DD232916A5 (en) 1986-02-12
NO163132C (en) 1990-04-11
KR850008154A (en) 1985-12-13
ES551275A0 (en) 1987-07-16
ZW7885A1 (en) 1985-07-24
EG17193A (en) 1990-08-30
ES8609248A1 (en) 1986-07-16
MA20424A1 (en) 1985-12-31

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Legal Events

Date Code Title Description
HU90 Patent valid on 900628