BG108759A - Метод за получаване на 2-(заместен фенил)-2- хидроксиетилкарбамати - Google Patents

Метод за получаване на 2-(заместен фенил)-2- хидроксиетилкарбамати Download PDF

Info

Publication number
BG108759A
BG108759A BG108759A BG10875904A BG108759A BG 108759 A BG108759 A BG 108759A BG 108759 A BG108759 A BG 108759A BG 10875904 A BG10875904 A BG 10875904A BG 108759 A BG108759 A BG 108759A
Authority
BG
Bulgaria
Prior art keywords
compound
formula
protecting group
alcohol
substituted phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
BG108759A
Other languages
Bulgarian (bg)
English (en)
Inventor
Thomas Otten
Daniel Korey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ortho-McNeil Pharmaceutical Inc
Original Assignee
Ortho-McNeil Pharmaceutical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho-McNeil Pharmaceutical Inc filed Critical Ortho-McNeil Pharmaceutical Inc
Publication of BG108759A publication Critical patent/BG108759A/bg
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/734—Ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/12—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14—Unsaturated ethers
    • C07C43/178—Unsaturated ethers containing hydroxy or O-metal groups
    • C07C43/1786—Unsaturated ethers containing hydroxy or O-metal groups containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BG108759A 2001-12-21 2004-06-11 Метод за получаване на 2-(заместен фенил)-2- хидроксиетилкарбамати Pending BG108759A (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01205097 2001-12-21
US41808402P 2002-10-11 2002-10-11

Publications (1)

Publication Number Publication Date
BG108759A true BG108759A (bg) 2005-03-31

Family

ID=26077052

Family Applications (1)

Application Number Title Priority Date Filing Date
BG108759A Pending BG108759A (bg) 2001-12-21 2004-06-11 Метод за получаване на 2-(заместен фенил)-2- хидроксиетилкарбамати

Country Status (22)

Country Link
EP (2) EP2248799B1 (no)
JP (1) JP4610899B2 (no)
KR (1) KR20090097966A (no)
CN (1) CN100457723C (no)
AR (1) AR038055A1 (no)
AU (3) AU2002358806B2 (no)
BG (1) BG108759A (no)
BR (1) BR0215237A (no)
CA (2) CA2471485C (no)
CZ (1) CZ2004718A3 (no)
EE (1) EE05381B1 (no)
HR (1) HRP20040557A2 (no)
HU (1) HUP0402491A2 (no)
IL (3) IL162405A0 (no)
MX (1) MXPA04006135A (no)
MY (1) MY142415A (no)
NO (1) NO20043105L (no)
NZ (1) NZ533592A (no)
PL (1) PL370977A1 (no)
SK (1) SK2572004A3 (no)
TW (1) TWI333944B (no)
WO (1) WO2003053916A1 (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7767843B2 (en) * 2006-03-02 2010-08-03 Apotex Pharmachem Inc. Process for the preparation of phenylcarbamates
CN101657195A (zh) * 2006-10-06 2010-02-24 詹森药业有限公司 氨基甲酸(s)-(+)-2-(2-氯代苯基)-2-羟基乙酯的新型晶体
US20090105498A1 (en) * 2007-10-18 2009-04-23 Porstmann Frank Improved process for preparing 2-(substituted phenyol)-2-hydroxy-ethyl-carbamates
US8609849B1 (en) 2010-11-30 2013-12-17 Fox Chase Chemical Diversity Center, Inc. Hydroxylated sulfamides exhibiting neuroprotective action and their method of use
JP2015504054A (ja) * 2011-12-27 2015-02-05 バイオ−ファーム ソリューションズ カンパニー リミテッド 多発性硬化症の治療または予防に使用されるフェニルカルバメート化合物
KR102421006B1 (ko) * 2016-05-19 2022-07-14 에스케이바이오팜 주식회사 두통의 예방학적 치료를 위한 카바메이트 화합물의 용도

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR5671M (no) * 1965-04-23 1968-01-02
US5504108A (en) * 1990-01-12 1996-04-02 The Ohio State University Research Foundation Optically pure 4-aryl-2-hydroxytetronic acids
JP3010497B2 (ja) * 1990-05-31 2000-02-21 チッソ株式会社 光学活性α―ヒドロキシエステル類の製造方法
DE69512888T2 (de) 1994-10-19 2000-06-15 Firmenich & Cie Verfahren zur herstellung von alkoholen
US5698588A (en) 1996-01-16 1997-12-16 Yukong Limited Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol
WO2001040168A1 (fr) * 1999-11-29 2001-06-07 Mitsubishi Rayon Co., Ltd. Derive d'acetalsulfonate, son procede de fabrication et obtention d'un derive d'oxyde styrene

Also Published As

Publication number Publication date
MY142415A (en) 2010-11-30
CZ2004718A3 (cs) 2004-12-15
CA2471485A1 (en) 2003-07-03
MXPA04006135A (es) 2004-11-01
HUP0402491A2 (hu) 2005-04-28
EP1461309A1 (en) 2004-09-29
EP2248799B1 (en) 2015-05-20
AU2002358806A1 (en) 2003-07-09
EE200400098A (et) 2004-10-15
WO2003053916A1 (en) 2003-07-03
KR20090097966A (ko) 2009-09-16
EP2248799A1 (en) 2010-11-10
JP2005513126A (ja) 2005-05-12
CA2681964A1 (en) 2003-07-03
AU2002358806B2 (en) 2009-09-10
SK2572004A3 (sk) 2005-02-04
BR0215237A (pt) 2004-11-16
AR038055A1 (es) 2004-12-22
CN1620425A (zh) 2005-05-25
EE05381B1 (et) 2011-02-15
PL370977A1 (en) 2005-06-13
HRP20040557A2 (en) 2005-04-30
IL162405A0 (en) 2005-11-20
NZ533592A (en) 2006-05-26
CA2471485C (en) 2011-05-24
CN100457723C (zh) 2009-02-04
IL162405A (en) 2011-08-31
TW200405809A (en) 2004-04-16
IL213960A0 (en) 2011-08-31
TWI333944B (en) 2010-12-01
NO20043105L (no) 2004-07-20
AU2011201613A1 (en) 2011-04-28
AU2009212987A1 (en) 2009-10-01
JP4610899B2 (ja) 2011-01-12

Similar Documents

Publication Publication Date Title
EP2387556B1 (de) Trennung eines enantiomerengemischs von (r)- und (s)-3-amino-1-butanol
JP2009522227A (ja) タミフルの合成におけるエポキシド中間体
JP2022163113A (ja) プリン誘導体を調製するための方法
AU2009212987A1 (en) Process for preparing 2-(substituted phenyl)-2-hydroxy-ethyl carbamates
JP2023526402A (ja) ブチル－（５ｓ）－５－（｛２－［４－（ブトキシカルボニル）フェニル］エチル｝［２－（２－｛［３－クロロ－４′－（トリフルオロメチル）［ビフェニル］－４－イル］メトキシ｝フェニル）エチル］アミノ）－５，６，７，８－テトラヒドロキノリン－２－カルボキシレートの製造方法
KR100945720B1 (ko) 2-(치환된 페닐)-2-하이드록시-에틸 카바메이트의 제조방법
EP3356342B1 (en) Process and intermediates for the preparation of benzo[b]thiophene compounds
KR20140065036A (ko) 고순도 보센탄의 개선된 제조방법
JP4829418B2 (ja) 光学活性なハロヒドリン誘導体およびその使用方法
JPH08151354A (ja) アミノアセトアミド誘導体の製造法
EP3145904A1 (en) Improved process for preparing substituted crotonic acids
JP2999306B2 (ja) エステル基を有するイミダゾリンの製造方法
EP2855421B1 (en) Process for the preparation of optically active 3,3-diphenylpropylamines
EP4219443A1 (en) Method for preparing intermediate for synthesis of sphingosine-1-phosphate receptor agonist
CN115710213A (zh) 一种顺式手性3-氟-4-羟基哌啶及其衍生物的制备方法
CN117203189A (zh) 制备用于合成鞘氨醇-1-磷酸酯受体激动剂的中间体的方法
JPH07233164A (ja) ピロカルピン誘導体の製造方法
JPS6121623B2 (no)
JP2002069069A (ja) ３，５，６−トリヒドロキシヘキサン酸アンモニウム塩誘導体、及びその製造方法
JP2004123640A (ja) ３−ニトロ−１，８−ナフチリジン−２（１ｈ）−オン誘導体の製造法