BG107277A - Използване на заместени триазолопиримидини като противоракови средства - Google Patents

Използване на заместени триазолопиримидини като противоракови средства Download PDF

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Publication number
BG107277A
BG107277A BG107277A BG10727702A BG107277A BG 107277 A BG107277 A BG 107277A BG 107277 A BG107277 A BG 107277A BG 10727702 A BG10727702 A BG 10727702A BG 107277 A BG107277 A BG 107277A
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BG
Bulgaria
Prior art keywords
chloro
triazolo
carbon atoms
pyrimidine
amine
Prior art date
Application number
BG107277A
Other languages
Bulgarian (bg)
English (en)
Inventor
Mark R. Schmitt
Donald R. Kirsch
Jane E. Harris
Carl F. Beyer
Klaus-Juergen Pees
Paul Carter
Waldemar Pfrengle
Guido Albert
Original Assignee
Wyeth
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth filed Critical Wyeth
Publication of BG107277A publication Critical patent/BG107277A/bg

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
BG107277A 2000-06-30 2002-11-15 Използване на заместени триазолопиримидини като противоракови средства BG107277A (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21558500P 2000-06-30 2000-06-30
PCT/US2001/020672 WO2002002563A2 (en) 2000-06-30 2001-06-28 Substituted-triazolopyrimidines as anticancer agents

Publications (1)

Publication Number Publication Date
BG107277A true BG107277A (bg) 2004-01-30

Family

ID=22803554

Family Applications (1)

Application Number Title Priority Date Filing Date
BG107277A BG107277A (bg) 2000-06-30 2002-11-15 Използване на заместени триазолопиримидини като противоракови средства

Country Status (24)

Country Link
US (1) US7329663B2 (ja)
EP (1) EP1307200A2 (ja)
JP (1) JP2004502691A (ja)
KR (1) KR20030013475A (ja)
CN (1) CN1592624A (ja)
AR (1) AR034553A1 (ja)
AU (2) AU7306201A (ja)
BG (1) BG107277A (ja)
BR (1) BR0112038A (ja)
CA (1) CA2413802A1 (ja)
CZ (1) CZ20024150A3 (ja)
EA (1) EA006483B1 (ja)
GE (1) GEP20053688B (ja)
HK (1) HK1052646A1 (ja)
HU (1) HUP0300798A3 (ja)
IL (1) IL152869A0 (ja)
IN (1) IN2003KO00001A (ja)
MX (1) MXPA02011913A (ja)
NO (1) NO20026195L (ja)
NZ (1) NZ523807A (ja)
PL (1) PL360027A1 (ja)
SK (1) SK18412002A3 (ja)
WO (1) WO2002002563A2 (ja)
ZA (1) ZA200300793B (ja)

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JP4606015B2 (ja) * 2003-11-25 2011-01-05 日本化薬株式会社 ［１，２，４］トリアゾロ［１，５−ａ］ピリミジン誘導体の新規医薬用途
MY179926A (en) 2003-12-08 2020-11-19 Wyeth Corp Process for the preparation of tubulin inhibitors
EP1697373A1 (de) * 2003-12-17 2006-09-06 Basf Aktiengesellschaft 6-(2,4,6-trihalogenphenyl)-triazolopyrimidine, verfahren zu ihrer herstellung und ihre verwendung zur bek mpfung von schadpil zen sowie sie enthaltende mittel
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Also Published As

Publication number Publication date
SK18412002A3 (sk) 2003-06-03
EA200300091A1 (ru) 2003-08-28
PL360027A1 (en) 2004-09-06
MXPA02011913A (es) 2003-04-22
GEP20053688B (en) 2005-12-12
US20020068744A1 (en) 2002-06-06
CA2413802A1 (en) 2002-01-10
CN1592624A (zh) 2005-03-09
NZ523807A (en) 2004-09-24
IL152869A0 (en) 2003-06-24
EP1307200A2 (en) 2003-05-07
NO20026195L (no) 2003-02-27
HUP0300798A2 (hu) 2003-07-28
WO2002002563A3 (en) 2003-01-03
WO2002002563A2 (en) 2002-01-10
CZ20024150A3 (cs) 2003-09-17
HK1052646A1 (zh) 2003-09-26
EA006483B1 (ru) 2005-12-29
NO20026195D0 (no) 2002-12-23
IN2003KO00001A (ja) 2005-12-02
AU7306201A (en) 2002-01-14
KR20030013475A (ko) 2003-02-14
JP2004502691A (ja) 2004-01-29
ZA200300793B (en) 2004-07-20
BR0112038A (pt) 2003-04-01
US7329663B2 (en) 2008-02-12
HUP0300798A3 (en) 2006-02-28
AR034553A1 (es) 2004-03-03
AU2001273062B2 (en) 2005-11-24

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