BG106369A - Метод за получаване на изотретиноин - Google Patents
Метод за получаване на изотретиноин Download PDFInfo
- Publication number
- BG106369A BG106369A BG106369A BG10636902A BG106369A BG 106369 A BG106369 A BG 106369A BG 106369 A BG106369 A BG 106369A BG 10636902 A BG10636902 A BG 10636902A BG 106369 A BG106369 A BG 106369A
- Authority
- BG
- Bulgaria
- Prior art keywords
- acid
- isotretinoin
- formula
- solvent
- water
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/20—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/353—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by isomerisation; by change of size of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/32—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1037DE1999 IN190846B (de) | 1999-07-30 | 1999-07-30 | |
| US09/467,201 US6441226B1 (en) | 1999-07-30 | 1999-12-20 | Process for the preparation of isotretinoin |
| PCT/IB2000/001020 WO2001009089A1 (en) | 1999-07-30 | 2000-07-24 | Process for the preparation of isotretinoin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG106369A true BG106369A (bg) | 2002-08-30 |
Family
ID=26324696
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG106369A BG106369A (bg) | 1999-07-30 | 2002-01-30 | Метод за получаване на изотретиноин |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP1204637B1 (de) |
| JP (1) | JP2003506349A (de) |
| CN (1) | CN1167679C (de) |
| AP (1) | AP2002002414A0 (de) |
| AT (1) | ATE293596T1 (de) |
| AU (1) | AU778584B2 (de) |
| BG (1) | BG106369A (de) |
| BR (1) | BR0012866A (de) |
| CA (1) | CA2380026A1 (de) |
| DE (1) | DE60019611T2 (de) |
| EA (1) | EA004651B1 (de) |
| EE (1) | EE200200053A (de) |
| ES (1) | ES2240117T3 (de) |
| HK (1) | HK1046901B (de) |
| HR (1) | HRP20020098A2 (de) |
| HU (1) | HUP0202230A3 (de) |
| IL (1) | IL147918A0 (de) |
| MX (1) | MXPA02001107A (de) |
| OA (1) | OA12002A (de) |
| PL (1) | PL353491A1 (de) |
| PT (1) | PT1204637E (de) |
| SK (1) | SK1612002A3 (de) |
| TR (1) | TR200200455T2 (de) |
| WO (1) | WO2001009089A1 (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104447459A (zh) * | 2014-11-28 | 2015-03-25 | 重庆华邦制药有限公司 | 异维a酸的新晶型及其制备方法与应用 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2951853A (en) * | 1957-06-08 | 1960-09-06 | Sumitomo Chemical Co | Method for preparing polyenecarboxylic acid derivatives |
-
2000
- 2000-07-24 CA CA002380026A patent/CA2380026A1/en not_active Abandoned
- 2000-07-24 IL IL14791800A patent/IL147918A0/xx not_active IP Right Cessation
- 2000-07-24 ES ES00944156T patent/ES2240117T3/es not_active Expired - Lifetime
- 2000-07-24 HU HU0202230A patent/HUP0202230A3/hu unknown
- 2000-07-24 JP JP2001514293A patent/JP2003506349A/ja active Pending
- 2000-07-24 TR TR2002/00455T patent/TR200200455T2/xx unknown
- 2000-07-24 EP EP00944156A patent/EP1204637B1/de not_active Expired - Lifetime
- 2000-07-24 AU AU58388/00A patent/AU778584B2/en not_active Ceased
- 2000-07-24 MX MXPA02001107A patent/MXPA02001107A/es active IP Right Grant
- 2000-07-24 BR BR0012866-0A patent/BR0012866A/pt not_active IP Right Cessation
- 2000-07-24 DE DE60019611T patent/DE60019611T2/de not_active Expired - Fee Related
- 2000-07-24 AP APAP/P/2002/002414A patent/AP2002002414A0/en unknown
- 2000-07-24 SK SK161-2002A patent/SK1612002A3/sk unknown
- 2000-07-24 EE EEP200200053A patent/EE200200053A/xx unknown
- 2000-07-24 EA EA200200110A patent/EA004651B1/ru not_active IP Right Cessation
- 2000-07-24 WO PCT/IB2000/001020 patent/WO2001009089A1/en active IP Right Grant
- 2000-07-24 CN CNB008119988A patent/CN1167679C/zh not_active Expired - Fee Related
- 2000-07-24 OA OA1200200035A patent/OA12002A/en unknown
- 2000-07-24 PT PT00944156T patent/PT1204637E/pt unknown
- 2000-07-24 AT AT00944156T patent/ATE293596T1/de not_active IP Right Cessation
- 2000-07-24 PL PL00353491A patent/PL353491A1/xx not_active Application Discontinuation
-
2002
- 2002-01-30 HR HR20020098A patent/HRP20020098A2/xx not_active Application Discontinuation
- 2002-01-30 BG BG106369A patent/BG106369A/bg unknown
- 2002-11-08 HK HK02108127.7A patent/HK1046901B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| HRP20020098A2 (en) | 2003-12-31 |
| CA2380026A1 (en) | 2001-02-08 |
| EP1204637B1 (de) | 2005-04-20 |
| CN1371362A (zh) | 2002-09-25 |
| IL147918A0 (en) | 2002-08-14 |
| HUP0202230A3 (en) | 2004-03-01 |
| CN1167679C (zh) | 2004-09-22 |
| EA004651B1 (ru) | 2004-06-24 |
| MXPA02001107A (es) | 2002-08-20 |
| BR0012866A (pt) | 2002-07-09 |
| HK1046901B (zh) | 2005-09-23 |
| AP2002002414A0 (en) | 2002-03-31 |
| PT1204637E (pt) | 2005-08-31 |
| HUP0202230A2 (hu) | 2002-11-28 |
| PL353491A1 (en) | 2003-11-17 |
| DE60019611T2 (de) | 2006-03-02 |
| HK1046901A1 (en) | 2003-01-30 |
| ATE293596T1 (de) | 2005-05-15 |
| EA200200110A1 (ru) | 2002-08-29 |
| DE60019611D1 (de) | 2005-05-25 |
| EP1204637A1 (de) | 2002-05-15 |
| JP2003506349A (ja) | 2003-02-18 |
| AU778584B2 (en) | 2004-12-09 |
| OA12002A (en) | 2006-04-18 |
| WO2001009089A1 (en) | 2001-02-08 |
| SK1612002A3 (en) | 2002-06-04 |
| ES2240117T3 (es) | 2005-10-16 |
| AU5838800A (en) | 2001-02-19 |
| TR200200455T2 (tr) | 2002-07-22 |
| EE200200053A (et) | 2003-04-15 |
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