BG105665A - Лекарствена форма с контролирано освобождаване, съдържаща натриев дивалпроекс - Google Patents

Лекарствена форма с контролирано освобождаване, съдържаща натриев дивалпроекс Download PDF

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Publication number
BG105665A
BG105665A BG105665A BG10566501A BG105665A BG 105665 A BG105665 A BG 105665A BG 105665 A BG105665 A BG 105665A BG 10566501 A BG10566501 A BG 10566501A BG 105665 A BG105665 A BG 105665A
Authority
BG
Bulgaria
Prior art keywords
weight percent
microns
weight
particle size
silica
Prior art date
Application number
BG105665A
Other languages
Bulgarian (bg)
English (en)
Inventor
Yihong Qui
Richard POSKA
Howard CHESKIN
J. Bollinger
Kevin ENGH
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/216,650 external-priority patent/US6419953B1/en
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of BG105665A publication Critical patent/BG105665A/bg

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Pain & Pain Management (AREA)
  • Inorganic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BG105665A 1998-12-18 2001-07-03 Лекарствена форма с контролирано освобождаване, съдържаща натриев дивалпроекс BG105665A (bg)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/216,650 US6419953B1 (en) 1998-12-18 1998-12-18 Controlled release formulation of divalproex sodium
US12155799P 1999-02-25 1999-02-25
PCT/US1999/029204 WO2000037055A1 (en) 1998-12-18 1999-12-09 Controlled release formulation of divalproex sodium

Publications (1)

Publication Number Publication Date
BG105665A true BG105665A (bg) 2002-03-29

Family

ID=26819594

Family Applications (1)

Application Number Title Priority Date Filing Date
BG105665A BG105665A (bg) 1998-12-18 2001-07-03 Лекарствена форма с контролирано освобождаване, съдържаща натриев дивалпроекс

Country Status (25)

Country Link
EP (1) EP1140034B1 (es)
JP (1) JP2003513882A (es)
KR (1) KR20010101295A (es)
CN (1) CN1335769A (es)
AR (1) AR021443A1 (es)
AT (1) ATE254907T1 (es)
AU (1) AU2478900A (es)
BG (1) BG105665A (es)
BR (1) BR9916361A (es)
CA (1) CA2330480C (es)
CO (1) CO5160287A1 (es)
CZ (1) CZ20012201A3 (es)
DE (1) DE69913197T2 (es)
DK (1) DK1140034T3 (es)
ES (1) ES2212667T3 (es)
HK (1) HK1043043B (es)
HU (1) HUP0105463A3 (es)
IL (1) IL143407A0 (es)
NO (1) NO20012986L (es)
PL (1) PL356899A1 (es)
PT (1) PT1140034E (es)
SI (1) SI20624A (es)
SK (1) SK8252001A3 (es)
TW (1) TW585788B (es)
WO (1) WO2000037055A1 (es)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6511678B2 (en) 1998-12-18 2003-01-28 Abbott Laboratories Controlled release formulation of divalproex sodium
US20020025341A1 (en) * 1998-12-18 2002-02-28 Yihong Qiu Controlled release formulation of divalproex sodium
US6528090B2 (en) 1998-12-18 2003-03-04 Abbott Laboratories Controlled release formulation of divalproex sodium
US6419953B1 (en) 1998-12-18 2002-07-16 Abbott Laboratories Controlled release formulation of divalproex sodium
US6713086B2 (en) 1998-12-18 2004-03-30 Abbott Laboratories Controlled release formulation of divalproex sodium
WO2002051402A1 (en) * 2000-12-22 2002-07-04 Abbott Laboratories Controlled release formulation of divalproex sodium
IL158959A (en) 2001-05-25 2010-06-30 Cephalon Inc Solid pharmaceutical formulations comprising modafinil
US7229644B2 (en) * 2002-05-23 2007-06-12 Cephalon, Inc. Pharmaceutical formulations of modafinil
US20040005357A1 (en) * 2002-07-03 2004-01-08 Sherman Bernard Charles Extended-release tablets comprising divalproex sodium
US20040048931A1 (en) 2002-07-12 2004-03-11 Craig Heacock Modafinil pharmaceutical compositions
US20040116532A1 (en) 2002-09-13 2004-06-17 Craig Heacock Pharmaceutical formulations of modafinil
WO2004082615A2 (en) * 2003-03-14 2004-09-30 Nirmal Mulye A process for preparing sustained release tablets
HUP0301537A3 (en) * 2003-06-03 2005-07-28 Egis Gyogyszergyar Nyilvanosan Deramcyclane fumarate tablets and process for producing them
US7713550B2 (en) 2004-06-15 2010-05-11 Andrx Corporation Controlled release sodium valproate formulation
WO2006025029A2 (en) * 2004-08-31 2006-03-09 Ranbaxy Laboratories Limited Extended release composition of divalproex
EA200701591A1 (ru) * 2005-01-26 2008-02-28 Элан Фарма Интернэшнл Лимитед Композиции с контролируемым высвобождением, содержащие антипсихотическое средство
US20070202164A1 (en) * 2006-02-28 2007-08-30 Hutchison Medipharma Enterprises Limited Andrographis Extract Formulations
JP5866279B2 (ja) * 2009-05-12 2016-02-17 株式会社アモーレパシフィックＡｍｏｒｅｐａｃｉｆｉｃ Ｃｏｒｐｏｒａｔｉｏｎ 脱毛防止又は育毛促進のための組成物
WO2012121862A2 (en) * 2011-02-17 2012-09-13 University Of Florida Research Foundation Valproic acid derivative compounds
CN102138911B (zh) * 2011-03-28 2012-12-12 孙卫东 一种双丙戊酸钠缓释片及其制备方法
CN102895201B (zh) * 2011-07-26 2014-09-10 北大方正集团有限公司 丙戊酸半钠片剂及其制备方法
EP2919903B1 (en) 2012-11-14 2020-07-22 W.R. Grace & CO. - CONN. Compositions containing a biologically active material and a non-ordered inorganic oxide
CN105012264B (zh) * 2014-04-16 2019-11-29 四川科瑞德制药股份有限公司 丙戊酸钠缓释片及其制备工艺和用途
CN106389368B (zh) * 2015-07-29 2021-11-12 四川科瑞德制药股份有限公司 一种丙戊酸钠缓释制剂及其制备工艺和用途
CN105456218A (zh) * 2015-12-07 2016-04-06 黑龙江省智诚医药科技有限公司 一种丙戊酸镁缓释片及其制备方法
CN107028907B (zh) * 2016-02-04 2021-05-14 成都康弘药业集团股份有限公司 一种双丙戊酸钠缓释片
CN114681419A (zh) * 2020-12-28 2022-07-01 湖南省湘中制药有限公司 一种丙戊酰胺缓释片的组合物及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5169642A (en) * 1988-06-24 1992-12-08 Abbott Laboratories Sustained-release drug dosage units
US5009897A (en) * 1988-06-24 1991-04-23 Abbott Laboratories Pharmaceutical granules and tablets made therefrom
FR2643556B1 (fr) * 1989-02-27 1993-03-05 Sanofi Sa Composition pharmaceutique a liberation prolongee d'acide valproique
IL96311A (en) * 1989-12-01 1995-05-26 Abbott Lab Medications with delayed release
US5075114A (en) * 1990-05-23 1991-12-24 Mcneil-Ppc, Inc. Taste masking and sustained release coatings for pharmaceuticals
TW224049B (es) * 1991-12-31 1994-05-21 Sunkyong Ind Ltd
TW222585B (es) * 1992-09-11 1994-04-21 Hoechst Ag
JP3552285B2 (ja) * 1993-08-03 2004-08-11 三菱化学株式会社 経口コレステロール低下剤
GB9501127D0 (en) * 1995-01-20 1995-03-08 Wellcome Found Tablet
CA2216215A1 (en) * 1997-04-05 1998-10-05 Isa Odidi Controlled release formulations using intelligent polymers having opposing wettability characteristics of hydrophobicity and hydrophilicity

Also Published As

Publication number Publication date
CN1335769A (zh) 2002-02-13
DE69913197D1 (de) 2004-01-08
AR021443A1 (es) 2002-07-17
DE69913197T2 (de) 2004-09-02
CZ20012201A3 (cs) 2001-09-12
HK1043043B (zh) 2004-09-10
HUP0105463A2 (hu) 2002-05-29
PL356899A1 (en) 2004-07-12
BR9916361A (pt) 2002-11-05
IL143407A0 (en) 2002-04-21
PT1140034E (pt) 2004-03-31
ATE254907T1 (de) 2003-12-15
HK1043043A1 (en) 2002-09-06
WO2000037055A1 (en) 2000-06-29
CA2330480A1 (en) 2000-06-29
CO5160287A1 (es) 2002-05-30
EP1140034B1 (en) 2003-11-26
DK1140034T3 (da) 2004-03-08
ES2212667T3 (es) 2004-07-16
AU2478900A (en) 2000-07-12
EP1140034A1 (en) 2001-10-10
TW585788B (en) 2004-05-01
NO20012986D0 (no) 2001-06-15
KR20010101295A (ko) 2001-11-14
NO20012986L (no) 2001-08-15
SK8252001A3 (en) 2001-12-03
HUP0105463A3 (en) 2003-03-28
SI20624A (sl) 2002-02-28
JP2003513882A (ja) 2003-04-15
CA2330480C (en) 2002-05-21

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