BG104840A - МЕТОД ЗА ПОЛУЧАВАНЕ НА ПИРАЗОЛО/4,3,-d/-ПИРИМИДИН-7-ОН-3-ПИРИДИЛСУЛФОНИЛОВИ СЪЕДИНЕНИЯ И ТЕХНИ МЕЖДИННИ СЪЕДИНЕНИЯ - Google Patents

МЕТОД ЗА ПОЛУЧАВАНЕ НА ПИРАЗОЛО/4,3,-d/-ПИРИМИДИН-7-ОН-3-ПИРИДИЛСУЛФОНИЛОВИ СЪЕДИНЕНИЯ И ТЕХНИ МЕЖДИННИ СЪЕДИНЕНИЯ Download PDF

Info

Publication number
BG104840A
BG104840A BG104840A BG10484000A BG104840A BG 104840 A BG104840 A BG 104840A BG 104840 A BG104840 A BG 104840A BG 10484000 A BG10484000 A BG 10484000A BG 104840 A BG104840 A BG 104840A
Authority
BG
Bulgaria
Prior art keywords
compound
formula
agent
compounds
reaction
Prior art date
Application number
BG104840A
Other languages
Bulgarian (bg)
English (en)
Inventor
Keith DEVRIES
Philip LEVETT
Joanna NEGRI
Albert Wood
Original Assignee
Pfizer Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9924042.6A external-priority patent/GB9924042D0/en
Priority claimed from GB0018667A external-priority patent/GB0018667D0/en
Application filed by Pfizer Inc. filed Critical Pfizer Inc.
Publication of BG104840A publication Critical patent/BG104840A/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Reproductive Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
BG104840A 1999-10-11 2000-10-11 МЕТОД ЗА ПОЛУЧАВАНЕ НА ПИРАЗОЛО/4,3,-d/-ПИРИМИДИН-7-ОН-3-ПИРИДИЛСУЛФОНИЛОВИ СЪЕДИНЕНИЯ И ТЕХНИ МЕЖДИННИ СЪЕДИНЕНИЯ BG104840A (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9924042.6A GB9924042D0 (en) 1999-10-11 1999-10-11 Process for thr preparation of pyrazolo[4,3-D]pyrimidin-7-ones-3-pyridylsulphonyl compounds and intermediates thereof
GB0018667A GB0018667D0 (en) 2000-07-28 2000-07-28 Process for the preparation of pyrazolo [4,3-d] Pyrimidin-7-ones-3-pyridylsulphonyl compounds and intermediates thereof

Publications (1)

Publication Number Publication Date
BG104840A true BG104840A (bg) 2001-10-31

Family

ID=26244761

Family Applications (1)

Application Number Title Priority Date Filing Date
BG104840A BG104840A (bg) 1999-10-11 2000-10-11 МЕТОД ЗА ПОЛУЧАВАНЕ НА ПИРАЗОЛО/4,3,-d/-ПИРИМИДИН-7-ОН-3-ПИРИДИЛСУЛФОНИЛОВИ СЪЕДИНЕНИЯ И ТЕХНИ МЕЖДИННИ СЪЕДИНЕНИЯ

Country Status (39)

Country Link
EP (1) EP1092720B1 (hu)
JP (1) JP2001114783A (hu)
KR (1) KR100395718B1 (hu)
CN (1) CN1292379A (hu)
AR (1) AR029767A1 (hu)
AT (1) ATE286899T1 (hu)
AU (1) AU6543600A (hu)
BG (1) BG104840A (hu)
BR (1) BR0004787A (hu)
CA (1) CA2322995A1 (hu)
CO (1) CO5251476A1 (hu)
CZ (1) CZ20003754A3 (hu)
DE (1) DE60017330D1 (hu)
DZ (1) DZ3096A1 (hu)
EA (1) EA003145B1 (hu)
EE (1) EE200000537A (hu)
EG (1) EG22775A (hu)
GT (1) GT200000169A (hu)
HR (1) HRP20000674A2 (hu)
HU (1) HUP0003979A3 (hu)
ID (1) ID27539A (hu)
IL (1) IL138913A0 (hu)
IN (1) IN190477B (hu)
IS (1) IS5654A (hu)
MA (1) MA25867A1 (hu)
MX (1) MXPA00009936A (hu)
NO (1) NO316072B1 (hu)
NZ (1) NZ507431A (hu)
OA (1) OA11495A (hu)
PA (1) PA8504601A1 (hu)
PE (1) PE20010682A1 (hu)
PL (1) PL343140A1 (hu)
SG (1) SG97950A1 (hu)
SK (1) SK15052000A3 (hu)
SV (1) SV2002000194A (hu)
TN (1) TNSN00195A1 (hu)
TR (1) TR200002959A2 (hu)
UY (1) UY26388A1 (hu)
YU (1) YU59100A (hu)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU59100A (sh) * 1999-10-11 2003-10-31 Pfizer Inc. Postupak za dobijanje pirazolo (4,3-d) pirimidin-7-ona-3-piridilsulfonil jedinjenja i njihova intermedijera
TWI265925B (en) 1999-10-11 2006-11-11 Pfizer Pyrazolo[4,3-d]pyrimidin-7-ones useful in inhibiting type 5 cyclic guanosine 3',5'-monophosphate phosphodiesterases(cGMP PDE5), process and intermediates for their preparation, their uses and composition comprising them
US6809200B2 (en) * 2000-07-28 2004-10-26 Pfizer Inc. Process for the preparation of pyrazolo[4,3-d]pyrimidin-7-one compounds and intermediates thereof
JP2006219373A (ja) * 2003-06-13 2006-08-24 Daiichi Asubio Pharma Co Ltd Ｐｄｅ７阻害作用を有するピリジニルピラゾロピリミジノン誘導体
CA2629077C (en) * 2005-11-16 2014-03-18 F. Hoffmann-La Roche Ag Novel process for the preparation of thoc
KR101002490B1 (ko) * 2007-06-09 2010-12-17 동아제약주식회사 유데나필을 유효성분으로 함유하는 만성 심부전증 치료용약학적 조성물
CN103391941A (zh) * 2011-02-23 2013-11-13 辉瑞大药厂 用于治疗神经障碍的咪唑并[5,1-f][1,2,4]三嗪类
CA3227887A1 (en) * 2016-11-21 2018-05-24 Adama Agan Ltd. Process for preparing methoxy methyl pyridine dicarboxylate

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR199902646T2 (xx) * 1997-04-25 2000-05-22 Pfizer Inc. Seks�el bozuklu�un tedavisi i�in pirazolopirimidinonlar.
JP3721077B2 (ja) * 1998-04-20 2005-11-30 ファイザー・インク 性的不全を治療するためのピラゾロピリミジノンｃＧＭＰＰＤＥ５阻害剤
GB9823101D0 (en) * 1998-10-23 1998-12-16 Pfizer Ltd Pharmaceutically active compounds
KR100353014B1 (ko) * 1998-11-11 2002-09-18 동아제약 주식회사 발기부전 치료에 효과를 갖는 피라졸로피리미디논 화합물
YU59100A (sh) * 1999-10-11 2003-10-31 Pfizer Inc. Postupak za dobijanje pirazolo (4,3-d) pirimidin-7-ona-3-piridilsulfonil jedinjenja i njihova intermedijera

Also Published As

Publication number Publication date
NZ507431A (en) 2002-09-27
HU0003979D0 (en) 2000-12-28
CZ20003754A3 (cs) 2002-06-12
EA200000924A3 (ru) 2001-06-25
MA25867A1 (fr) 2003-10-01
EE200000537A (et) 2001-06-15
NO316072B1 (no) 2003-12-08
SV2002000194A (es) 2002-01-23
ATE286899T1 (de) 2005-01-15
HUP0003979A2 (hu) 2001-12-28
OA11495A (en) 2004-05-05
YU59100A (sh) 2003-10-31
KR20010050935A (ko) 2001-06-25
AU6543600A (en) 2001-04-12
EA003145B1 (ru) 2003-02-27
IN190477B (hu) 2003-08-02
CN1292379A (zh) 2001-04-25
PL343140A1 (en) 2001-04-23
SG97950A1 (en) 2003-08-20
DE60017330D1 (de) 2005-02-17
AR029767A1 (es) 2003-07-16
TNSN00195A1 (fr) 2005-11-10
HUP0003979A3 (en) 2002-03-28
MXPA00009936A (es) 2002-10-23
DZ3096A1 (fr) 2004-06-20
EG22775A (en) 2003-08-31
CO5251476A1 (es) 2003-02-28
JP2001114783A (ja) 2001-04-24
EA200000924A2 (ru) 2001-04-23
KR100395718B1 (ko) 2003-08-25
PE20010682A1 (es) 2001-07-04
CA2322995A1 (en) 2001-04-11
EP1092720A2 (en) 2001-04-18
BR0004787A (pt) 2001-05-22
IL138913A0 (en) 2001-11-25
SK15052000A3 (sk) 2003-01-09
ID27539A (id) 2001-04-12
PA8504601A1 (es) 2002-02-21
NO20005104L (no) 2001-04-17
UY26388A1 (es) 2001-05-31
NO20005104D0 (no) 2000-10-10
IS5654A (is) 2001-04-12
TR200002959A2 (tr) 2001-07-23
HRP20000674A2 (en) 2001-08-31
EP1092720B1 (en) 2005-01-12
EP1092720A3 (en) 2001-09-19
GT200000169A (es) 2002-04-03

Similar Documents

Publication Publication Date Title
KR100380954B1 (ko) 피라졸로[4,3-디]피리미딘-7-온 및 그의 중간체의 제조방법
KR20190013553A (ko) 아미노피리미딘 유도체의 개선된 제조방법
US6667398B2 (en) Process for the preparation of pyrazolopyrimidinones
BG104840A (bg) МЕТОД ЗА ПОЛУЧАВАНЕ НА ПИРАЗОЛО/4,3,-d/-ПИРИМИДИН-7-ОН-3-ПИРИДИЛСУЛФОНИЛОВИ СЪЕДИНЕНИЯ И ТЕХНИ МЕЖДИННИ СЪЕДИНЕНИЯ
CZ20012713A3 (cs) Způsob přípravy pyrazol[4,3-d]pyrimidin-7-onových sloučenin a jejich meziprodukty
EP1292586B1 (en) Process for the preparation of pyrazolopyrimidinones
EP0041359B1 (en) Process for the preparation of heterocyclylalkyl guanidines; intermediates and their preparation
JP4042164B2 (ja) １−（ヘテロ）アリール−３−ヒドロキシピラゾールの製造方法
KR100525699B1 (ko) 피라졸로피리미디논의 신규 제조 방법
JP2002193941A (ja) ピラゾール類の新規製造方法
US4375435A (en) 3-,4-Dihydroimidazo (3,4-c)-1,3-pyrimidines and 4,5-dihydroimidazo (3,4-c)-1,3-diazepines
EA041485B1 (ru) Усовершенствованный способ получения производных аминопиримидина
MXPA99009326A (en) Procedure for the preparation of pirazolo [4,3-d] pyrimidin-7-onas and its intermed