BG104413A - Метод за синтез на пироламиди - Google Patents
Метод за синтез на пироламидиInfo
- Publication number
- BG104413A BG104413A BG104413A BG10441300A BG104413A BG 104413 A BG104413 A BG 104413A BG 104413 A BG104413 A BG 104413A BG 10441300 A BG10441300 A BG 10441300A BG 104413 A BG104413 A BG 104413A
- Authority
- BG
- Bulgaria
- Prior art keywords
- synthesis
- reaction
- followed
- pyrrole amides
- pyrrole
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/83—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Indole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
- Tea And Coffee (AREA)
- Fats And Perfumes (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6542297P | 1997-11-13 | 1997-11-13 | |
US7426698P | 1998-02-10 | 1998-02-10 |
Publications (2)
Publication Number | Publication Date |
---|---|
BG104413A true BG104413A (bg) | 2001-02-28 |
BG64530B1 BG64530B1 (bg) | 2005-06-30 |
Family
ID=26745584
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG104413A BG64530B1 (bg) | 1997-11-13 | 2000-05-09 | Метод за синтез на пироламиди |
Country Status (35)
Country | Link |
---|---|
US (1) | US6262272B1 (bg) |
EP (1) | EP1030838B1 (bg) |
JP (1) | JP3497469B2 (bg) |
KR (1) | KR100386722B1 (bg) |
CN (2) | CN1508129A (bg) |
AT (1) | ATE231492T1 (bg) |
AU (1) | AU745788B2 (bg) |
BG (1) | BG64530B1 (bg) |
BR (1) | BR9814161A (bg) |
CA (1) | CA2310095A1 (bg) |
CZ (1) | CZ20001769A3 (bg) |
DE (1) | DE69810959T2 (bg) |
DK (1) | DK1030838T3 (bg) |
DZ (1) | DZ2651A1 (bg) |
EA (1) | EA002243B1 (bg) |
ES (1) | ES2186232T3 (bg) |
HR (1) | HRP20000298A2 (bg) |
HU (1) | HUP0100235A3 (bg) |
ID (1) | ID24135A (bg) |
IL (1) | IL135710A0 (bg) |
IS (1) | IS5469A (bg) |
MA (1) | MA24697A1 (bg) |
NO (1) | NO20002214L (bg) |
NZ (1) | NZ503916A (bg) |
OA (1) | OA11378A (bg) |
PA (1) | PA8462901A1 (bg) |
PL (1) | PL340554A1 (bg) |
PT (1) | PT1030838E (bg) |
SK (1) | SK6872000A3 (bg) |
TN (1) | TNSN98204A1 (bg) |
TR (1) | TR200001343T2 (bg) |
TW (1) | TW509675B (bg) |
UY (1) | UY25249A1 (bg) |
WO (1) | WO1999025684A1 (bg) |
YU (1) | YU27300A (bg) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1372546A (zh) | 1999-08-31 | 2002-10-02 | 神经原公司 | 稠合的吡咯甲酰胺:gaba脑受体的配体 |
BR0113697A (pt) * | 2000-09-06 | 2003-07-22 | Neurogen Corp | Composto ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica, uso de um composto ou sal, embalagem e métodos para, para alterar a atividade transdutora de sinal dos receptores de gabaa, para tratar ansiedade, depressão, um distúrbio do sono, ou demência de alzheimer, para demonstrar a presença dos receptores de gabaa em células ou amostras de tecido e para preparar um composto |
CA2430841A1 (en) * | 2000-12-04 | 2002-06-13 | Pfizer Products Inc. | Synthesis of fused pyrrolecarboxamides |
MXPA04007606A (es) | 2002-02-07 | 2004-11-10 | Neurogen Corp | Arilamidas de acido pirazolcarboxilico fusionadas substituidas y compuestos relacionados. |
US20080153629A1 (en) * | 2004-05-07 | 2008-06-26 | Sullivan Michael J | Thick Outer Cover Layer Golf Ball |
CN102786458B (zh) * | 2012-06-04 | 2014-02-12 | 天津渤海职业技术学院 | 吡咯甲酰胺衍生物、其制备方法和用途 |
CA2937074A1 (en) * | 2014-01-24 | 2015-07-30 | Abbvie Inc. | Furo-3-carboxamide derivatives and methods of use |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5750702A (en) | 1993-10-27 | 1998-05-12 | Neurogen Corporation | Certain pyrrolo pyridine-3-carboxamides; a new class of GABA brain receptor ligands |
US5484944A (en) * | 1993-10-27 | 1996-01-16 | Neurogen Corporation | Certain fused pyrrolecarboxanilides and their use as GABA brain receptor ligands |
US5804686A (en) | 1996-01-19 | 1998-09-08 | Neurogen Corporation | fused pyrrolecarboxamides; a new class of GABA brain receptor ligands |
AU2218997A (en) | 1996-03-22 | 1997-10-10 | Neurogen Corporation | Certain fused pyrrolecarboxamides as gaba brain receptor ligands |
-
1998
- 1998-10-21 PT PT98946678T patent/PT1030838E/pt unknown
- 1998-10-21 BR BR9814161-9A patent/BR9814161A/pt not_active Application Discontinuation
- 1998-10-21 SK SK687-2000A patent/SK6872000A3/sk unknown
- 1998-10-21 KR KR10-2000-7005185A patent/KR100386722B1/ko not_active IP Right Cessation
- 1998-10-21 YU YU27300A patent/YU27300A/sh unknown
- 1998-10-21 AU AU93639/98A patent/AU745788B2/en not_active Ceased
- 1998-10-21 DE DE69810959T patent/DE69810959T2/de not_active Expired - Fee Related
- 1998-10-21 CN CNA031594727A patent/CN1508129A/zh active Pending
- 1998-10-21 HU HU0100235A patent/HUP0100235A3/hu unknown
- 1998-10-21 CZ CZ20001769A patent/CZ20001769A3/cs unknown
- 1998-10-21 PL PL98340554A patent/PL340554A1/xx not_active Application Discontinuation
- 1998-10-21 IL IL13571098A patent/IL135710A0/xx unknown
- 1998-10-21 CA CA002310095A patent/CA2310095A1/en not_active Abandoned
- 1998-10-21 ES ES98946678T patent/ES2186232T3/es not_active Expired - Lifetime
- 1998-10-21 EP EP98946678A patent/EP1030838B1/en not_active Expired - Lifetime
- 1998-10-21 NZ NZ503916A patent/NZ503916A/xx unknown
- 1998-10-21 US US09/403,985 patent/US6262272B1/en not_active Expired - Fee Related
- 1998-10-21 JP JP2000521068A patent/JP3497469B2/ja not_active Expired - Fee Related
- 1998-10-21 WO PCT/IB1998/001672 patent/WO1999025684A1/en not_active Application Discontinuation
- 1998-10-21 DK DK98946678T patent/DK1030838T3/da active
- 1998-10-21 EA EA200000413A patent/EA002243B1/ru not_active IP Right Cessation
- 1998-10-21 AT AT98946678T patent/ATE231492T1/de not_active IP Right Cessation
- 1998-10-21 CN CN98811119A patent/CN1280566A/zh active Pending
- 1998-10-21 TR TR2000/01343T patent/TR200001343T2/xx unknown
- 1998-10-21 ID IDW20000893A patent/ID24135A/id unknown
- 1998-11-10 PA PA19988462901A patent/PA8462901A1/es unknown
- 1998-11-10 TW TW087118708A patent/TW509675B/zh not_active IP Right Cessation
- 1998-11-11 MA MA25342A patent/MA24697A1/fr unknown
- 1998-11-11 TN TNTNSN98204A patent/TNSN98204A1/fr unknown
- 1998-11-11 DZ DZ980261A patent/DZ2651A1/xx active
- 1998-11-13 UY UY25249A patent/UY25249A1/es not_active IP Right Cessation
-
2000
- 2000-04-26 IS IS5469A patent/IS5469A/is unknown
- 2000-04-28 NO NO20002214A patent/NO20002214L/no unknown
- 2000-05-09 BG BG104413A patent/BG64530B1/bg unknown
- 2000-05-12 OA OA1200000136A patent/OA11378A/en unknown
- 2000-05-12 HR HR20000298A patent/HRP20000298A2/hr not_active Application Discontinuation
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