BG103958A - Фармацевтични състави на тизоксанид и нитазоксанид - Google Patents

Фармацевтични състави на тизоксанид и нитазоксанид

Info

Publication number
BG103958A
BG103958A BG103958A BG10395899A BG103958A BG 103958 A BG103958 A BG 103958A BG 103958 A BG103958 A BG 103958A BG 10395899 A BG10395899 A BG 10395899A BG 103958 A BG103958 A BG 103958A
Authority
BG
Bulgaria
Prior art keywords
pharmaceutical compositions
compound
thioxanide
nitazoxanide
micro
Prior art date
Application number
BG103958A
Other languages
English (en)
Other versions
BG64973B1 (bg
Inventor
Jean-Francois Rossignol
Original Assignee
Romark Laboratories,L.C.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27420362&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BG103958(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/852,447 external-priority patent/US5968961A/en
Priority claimed from US08/887,809 external-priority patent/US5965590A/en
Priority claimed from US08/887,810 external-priority patent/US5856348A/en
Application filed by Romark Laboratories,L.C. filed Critical Romark Laboratories,L.C.
Publication of BG103958A publication Critical patent/BG103958A/bg
Publication of BG64973B1 publication Critical patent/BG64973B1/bg

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A61P33/12—Schistosomicides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Фармацевтичните състави са особено полезни за лечение на условно-патогенни инфекции у индивиди с компрометирана или потисната имунна система, както иза лечение на инфекции, причинени от трематоди. Те са за орално приложение и съдържат като активен агент най-малко едно съединение, избрано от групата, включваща съединение с формула и съединение с формула. За предпочитане активният агент е под формата на частици с размер под 200 m и среден размернад 10 m. Фармацевтичните състави, за предпочитане, са стабилизирани поне с една фармацевтично приемлива киселина.
BG103958A 1997-05-07 1999-12-06 Фармацевтични състави на тизоксанид и нитазоксанид BG64973B1 (bg)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/852,447 US5968961A (en) 1997-05-07 1997-05-07 Pharmaceutical compositions of tizoxanide and nitazoxanide
US08/887,809 US5965590A (en) 1994-09-08 1997-07-03 Method for treatment of opportunistic infections with pharmaceutical compositions of tizoxanide and nitazoxanide
US08/887,810 US5856348A (en) 1994-09-08 1997-07-03 Method for treatment of trematodes with pharmaceutical compositions of tizoxanide and nitazoxanide

Publications (2)

Publication Number Publication Date
BG103958A true BG103958A (bg) 2000-07-31
BG64973B1 BG64973B1 (bg) 2006-11-30

Family

ID=27420362

Family Applications (2)

Application Number Title Priority Date Filing Date
BG109365A BG109365A (bg) 1997-05-07 1998-12-06 Използване на фармацевтични състави на тизоксаниди нитазоксанид
BG103958A BG64973B1 (bg) 1997-05-07 1999-12-06 Фармацевтични състави на тизоксанид и нитазоксанид

Family Applications Before (1)

Application Number Title Priority Date Filing Date
BG109365A BG109365A (bg) 1997-05-07 1998-12-06 Използване на фармацевтични състави на тизоксаниди нитазоксанид

Country Status (35)

Country Link
EP (2) EP1222921B1 (bg)
JP (1) JP3739802B2 (bg)
KR (2) KR100426657B1 (bg)
CN (2) CN1158074C (bg)
AP (1) AP1103A (bg)
AR (1) AR057242A2 (bg)
AT (2) ATE281166T1 (bg)
AU (1) AU740022B2 (bg)
BG (2) BG109365A (bg)
BR (1) BR9808722A (bg)
CA (2) CA2418634C (bg)
CZ (2) CZ298269B6 (bg)
DE (2) DE69827417T2 (bg)
DK (2) DK1222921T3 (bg)
EA (2) EA002920B1 (bg)
EE (1) EE04870B1 (bg)
ES (2) ES2232687T3 (bg)
GE (1) GEP20032970B (bg)
HK (1) HK1025907A1 (bg)
HU (1) HU229641B1 (bg)
IL (2) IL155799A (bg)
IS (1) IS2087B (bg)
LV (1) LV12492B (bg)
ME (1) ME00530B (bg)
NO (2) NO313983B1 (bg)
NZ (2) NZ500149A (bg)
OA (1) OA11169A (bg)
PL (1) PL193275B1 (bg)
PT (2) PT1222921E (bg)
RO (1) RO120605B1 (bg)
SI (1) SI20149B (bg)
SK (2) SK283947B6 (bg)
TR (1) TR199902733T2 (bg)
UA (2) UA57079C2 (bg)
WO (1) WO1998050035A1 (bg)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2467321A1 (en) 2004-05-14 2005-11-14 Paul J. Santerre Polymeric coupling agents and pharmaceutically-active polymers made therefrom
CA2636527C (en) 2006-01-09 2016-05-17 Romark Laboratories, L.C. Viral hepatitis treatment
PL2395840T3 (pl) * 2009-02-13 2020-09-07 Romark Laboratories, L.C. Preparaty farmaceutyczne nitazoksanidu o kontrolowanym uwalnianiu
PE20121118A1 (es) 2009-05-12 2012-09-05 Romark Lab Lc Compuestos de haloalquil heteroaril benzamida
EP2445349B1 (en) 2009-06-26 2022-02-09 Romark Laboratories, L.C. Compounds and methods for treating influenza
US9498441B2 (en) 2012-01-27 2016-11-22 Siegfried Rhein S.A. De C.V. Nitazoxadine composition and process to prepare same
AU2015346413B2 (en) * 2014-11-11 2019-08-29 Romark Laboratories, L.C. Compositions and methods of treatment with prodrugs of tizoxanide, an analogue or salt thereof
US11612567B2 (en) 2018-02-02 2023-03-28 Ripple Therapeutics Corporation Ocular inserts comprising a covalently linked steroid dimer
EP4146664A2 (en) 2020-05-01 2023-03-15 Ripple Therapeutics Corporation Heterodimer compositions and methods for the treatment of ocular disorders
WO2022130406A1 (en) * 2020-12-15 2022-06-23 Cipla Limited Inhalation composition of nitazoxanide or its derivatives for use in coronavirus disease

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1437800A (en) * 1973-08-08 1976-06-03 Phavic Sprl Derivatives of 2-benzamido-5-nitro-thiazoles
US4315018A (en) * 1978-12-07 1982-02-09 Rossignol Jean F Specific parasiticidal use of 2-benzamido-5-nitro-thiazole derivatives
US5387598A (en) * 1994-04-13 1995-02-07 Rossignol; Jean-Francois Composition and galenic formulation suitable for combatting affections of the lower abdomen
US5578621A (en) * 1994-09-08 1996-11-26 Romark Lab Lc Benzamide derivatives

Also Published As

Publication number Publication date
KR20040004544A (ko) 2004-01-13
UA57079C2 (uk) 2003-06-16
AU740022B2 (en) 2001-10-25
KR100576646B1 (ko) 2006-05-08
NO335781B1 (no) 2015-02-16
HK1025907A1 (en) 2000-12-01
DE69809928T2 (de) 2003-04-24
SK283947B6 (sk) 2004-05-04
EP1005342A4 (en) 2001-02-07
UA74388C2 (uk) 2005-12-15
GEP20032970B (en) 2003-05-27
IL155799A (en) 2004-08-31
SI20149B (en) 2001-08-31
NO20021832L (no) 2000-01-04
AU7289598A (en) 1998-11-27
NO20021832D0 (no) 2002-04-18
BR9808722A (pt) 2000-07-11
CA2288003A1 (en) 1998-11-12
CZ298270B6 (cs) 2007-08-08
IL155799A0 (en) 2003-12-23
JP2001503067A (ja) 2001-03-06
CA2418634A1 (en) 1998-11-12
CZ391199A3 (cs) 2000-07-12
SK283946B6 (sk) 2004-05-04
EA199901012A1 (ru) 2000-08-28
OA11169A (en) 2003-04-25
KR100426657B1 (ko) 2004-04-13
DE69809928D1 (de) 2003-01-16
ES2150404T3 (es) 2003-07-01
CN1255060A (zh) 2000-05-31
AP9901675A0 (en) 1999-12-31
CA2418634C (en) 2004-10-26
CN1552322A (zh) 2004-12-08
NO995406D0 (no) 1999-11-04
CN100515420C (zh) 2009-07-22
NZ500149A (en) 2001-11-30
AP1103A (en) 2002-09-04
EP1222921A1 (en) 2002-07-17
EA002920B1 (ru) 2002-10-31
BG109365A (bg) 2006-08-31
SI20149A (sl) 2000-08-31
BG64973B1 (bg) 2006-11-30
PT1005342E (pt) 2003-02-28
DE69827417D1 (de) 2004-12-09
PT1222921E (pt) 2005-02-28
DK1005342T3 (da) 2003-03-24
CZ298269B6 (cs) 2007-08-08
TR199902733T2 (xx) 2000-03-21
EP1222921B1 (en) 2004-11-03
SK151199A3 (en) 2000-07-11
ES2232687T3 (es) 2005-06-01
CA2288003C (en) 2003-10-21
LV12492B (en) 2001-01-20
DE69827417T2 (de) 2005-10-27
WO1998050035A1 (en) 1998-11-12
NZ513881A (en) 2002-10-25
EE04870B1 (et) 2007-08-15
EA200100956A1 (ru) 2002-02-28
NO995406L (no) 2000-01-04
EP1005342B1 (en) 2002-12-04
IL132516A (en) 2003-12-10
ES2150404T1 (es) 2000-12-01
IL132516A0 (en) 2001-03-19
RO120605B1 (ro) 2006-05-30
HUP0003330A2 (hu) 2001-05-28
IS5223A (is) 1999-10-19
CN1158074C (zh) 2004-07-21
JP3739802B2 (ja) 2006-01-25
ATE228839T1 (de) 2002-12-15
IS2087B (is) 2006-03-15
AR057242A2 (es) 2007-11-21
KR20010020322A (ko) 2001-03-15
HUP0003330A3 (en) 2002-10-28
NO313983B1 (no) 2003-01-13
HU229641B1 (en) 2014-03-28
EA002908B1 (ru) 2002-10-31
EP1005342A1 (en) 2000-06-07
EE9900578A (et) 2000-08-15
LV12492A (en) 2000-06-20
PL336805A1 (en) 2000-07-17
ME00530B (me) 2011-10-10
PL193275B1 (pl) 2007-01-31
ATE281166T1 (de) 2004-11-15
DK1222921T3 (da) 2005-03-07

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