BG103797A - Composition and method for polynonsaturated fatty acid syntheses with a long chain - Google Patents

Composition and method for polynonsaturated fatty acid syntheses with a long chain

Info

Publication number
BG103797A
BG103797A BG103797A BG10379797A BG103797A BG 103797 A BG103797 A BG 103797A BG 103797 A BG103797 A BG 103797A BG 10379797 A BG10379797 A BG 10379797A BG 103797 A BG103797 A BG 103797A
Authority
BG
Bulgaria
Prior art keywords
acid
desaturase
fatty acid
polynonsaturated
composition
Prior art date
Application number
BG103797A
Other languages
Bulgarian (bg)
English (en)
Inventor
Deborah Knutzon
Pradip Mukerji
Yung - Sheng HUANG
Jennifer Thurmond
Sunita Chaudhary
Amanda LEONARD
Original Assignee
Abbott Laboratories
Calgene Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25267468&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BG103797(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbott Laboratories, Calgene Llc filed Critical Abbott Laboratories
Publication of BG103797A publication Critical patent/BG103797A/xx

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    • CCHEMISTRY; METALLURGY
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0071Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0083Miscellaneous (1.14.99)
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23DEDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
    • A23D9/00Other edible oils or fats, e.g. shortenings, cooking oils
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/158Fatty acids; Fats; Products containing oils or fats
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12Fatty acids or derivatives thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/40Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8247Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • C12P7/6427Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • C12P7/6427Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6431Linoleic acids [18:2[n-6]]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436Fatty acid esters
    • C12P7/6445Glycerides
    • C12P7/6472Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Chemical & Material Sciences (AREA)
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  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Food Science & Technology (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Pediatric Medicine (AREA)
  • Animal Husbandry (AREA)
  • Dermatology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Fats And Perfumes (AREA)
BG103797A 1997-04-11 1997-10-11 Composition and method for polynonsaturated fatty acid syntheses with a long chain BG103797A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/834,655 US5968809A (en) 1997-04-11 1997-04-11 Methods and compositions for synthesis of long chain poly-unsaturated fatty acids
PCT/US1998/007126 WO1998046763A1 (en) 1997-04-11 1998-04-10 Methods and compositions for synthesis of long chain polyunsaturated fatty acids

Publications (1)

Publication Number Publication Date
BG103797A true BG103797A (en) 2000-04-28

Family

ID=25267468

Family Applications (1)

Application Number Title Priority Date Filing Date
BG103797A BG103797A (en) 1997-04-11 1997-10-11 Composition and method for polynonsaturated fatty acid syntheses with a long chain

Country Status (23)

Country Link
US (5) US5968809A (hu)
EP (1) EP0975766B1 (hu)
JP (1) JP4355368B2 (hu)
KR (1) KR20010006257A (hu)
CN (1) CN1252099A (hu)
AT (1) ATE313630T1 (hu)
AU (1) AU726807B2 (hu)
BG (1) BG103797A (hu)
BR (1) BR9808507A (hu)
CA (1) CA2285968A1 (hu)
DE (1) DE69832874T2 (hu)
DK (1) DK0975766T3 (hu)
ES (1) ES2258816T3 (hu)
HU (1) HUP0001236A1 (hu)
IL (1) IL132150A0 (hu)
MX (1) MX212281B (hu)
NO (1) NO994925L (hu)
NZ (1) NZ337457A (hu)
PL (1) PL336143A1 (hu)
PT (1) PT975766E (hu)
SK (1) SK139899A3 (hu)
TR (1) TR199902465T2 (hu)
WO (1) WO1998046763A1 (hu)

Families Citing this family (132)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6483008B1 (en) * 1990-08-15 2002-11-19 Calgene Llc Methods for producing plants with elevated oleic acid content
US5968809A (en) * 1997-04-11 1999-10-19 Abbot Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids
US6432684B1 (en) * 1997-04-11 2002-08-13 Abbott Laboratories Human desaturase gene and uses thereof
US7745694B1 (en) 1997-04-11 2010-06-29 Monsanto Technology Llc Methods and compositions for synthesis of long chain polyunsaturated fatty acids in plants
GB9724783D0 (en) * 1997-11-24 1998-01-21 Inst Arable Crops Research Novel polypeptides
CA2329159A1 (en) * 1998-05-29 1999-12-02 Bruce Kelder Compositions and methods for the synthesis of fatty acids, their derivatives and downstream products
US6459018B1 (en) * 1998-06-12 2002-10-01 Monsanto Technology Llc Polyunsaturated fatty acids in plants
EP1035207A1 (en) * 1999-03-09 2000-09-13 MultiGene Biotech GmbH cDNA molecules of the members of gene family encoding human fatty acid desaturases and their use in diagnosis and therapy
US20080206841A1 (en) * 1999-04-06 2008-08-28 Lalgudi Raghunath V Nucleic acid sequences from Chlorella vulgaris and uses thereof
ATE334206T1 (de) 1999-06-07 2006-08-15 Basf Plant Science Gmbh Delta6-acetylenase und delta6-desaturase aus ceratodon purpureus
DE10030976A1 (de) 2000-06-30 2002-01-10 Basf Ag DELTA6-Desaturasegene exprimierende Pflanzen und PUFAS enthaltende Öle aus diesen Pflanzen und ein Verfahren zur Herstellung ungesättigter Fettsäuren
WO2001004636A1 (en) * 1999-07-12 2001-01-18 Ohio University Mammalian cells expressing desaturases and elongases
IL150414A0 (en) 2000-02-09 2002-12-01 Basf Ag Novel elongase gene and method for producing multiple-unsaturated fatty acid
PT1322752E (pt) * 2000-09-28 2010-05-06 Bioriginal Food & Science Corp Fad4, fad5, fad5-2 e fad6, novos membros da família de dessaturases de ácidos gordos e susas utilizações
ATE400189T1 (de) * 2001-03-23 2008-07-15 Advanced Bionutrition Corp Abgabe von mitteln zur krankheitskontrolle in aquakultur unter verwendung von bioaktive proteine enthaltender hefe
TWI324181B (en) * 2001-04-16 2010-05-01 Martek Biosciences Corp Product and process for transformation of thraustochytriales microorganisms
MXPA03010467A (es) * 2001-05-14 2004-12-06 Martek Biosciences Boulder Corp Produccion y uso de una fraccion polar rica en lipidos que contienen acido estearidonico y acido gama-linolenico proviniente de semillas y microbios.
WO2002092540A1 (en) * 2001-05-14 2002-11-21 Martek Biosciences Corporation Production and use of a polar lipid-rich fraction containing omega-3 and/or omega-6 highly unsatruated fatty acids from microbes, genetically modified plant seeds and marine organisms
DE50312241D1 (de) 2002-01-30 2010-01-28 Basf Plant Science Gmbh Verfahren zur herstellung mehrfach ungesättigter f
US7211656B2 (en) 2002-01-30 2007-05-01 Abbott Laboratories Desaturase genes, enzymes encoded thereby, and uses thereof
GB2385852A (en) 2002-02-27 2003-09-03 Rothamsted Ex Station Delta 6-desaturases from Primulaceae
DE10219203A1 (de) 2002-04-29 2003-11-13 Basf Plant Science Gmbh Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren in Pflanzen
JP4515904B2 (ja) 2002-05-22 2010-08-04 モンサント テクノロジー エルエルシー 真菌からの脂肪酸不飽和化酵素
DE10232621A1 (de) * 2002-07-14 2004-02-12 Stiftung Alfred-Wegener-Institut Für Polar- Und Meeresforschung Für ein Enzym Delta-12-Desaturase kodierende Nukleinsäuresequenz, zugehöriges Polypeptid und Verwendung von beiden
FR2844142B1 (fr) 2002-09-11 2007-08-17 Bayer Cropscience Sa Plantes transformees a biosynthese de prenylquinones amelioree
US7244874B2 (en) * 2002-09-17 2007-07-17 The Regents Of The University Of California Stearoyl CoA desaturase transgenic non-human animals
US8841344B2 (en) * 2002-10-03 2014-09-23 Hill's Pet Nutrition, Inc. Method of using omega-3 fatty acids
US20040209953A1 (en) * 2002-12-06 2004-10-21 Wai Lee Theresa Siu-Ling Glyceride compositions and methods of making and using same
FR2848570B1 (fr) 2002-12-12 2005-04-01 Bayer Cropscience Sa Cassette d'expression codant pour une 5-enol pyruvylshikimate-3-phosphate synthase (epsps) et plantes tolerantes aux herbicides la contenant
GB0229578D0 (en) * 2002-12-19 2003-01-22 Univ Bristol Novel method for the production of polyunsaturated fatty acids
BR0317304A (pt) 2002-12-19 2005-11-08 Univ Bristol Processo para a produção de compostos, sequência de ácido nucleico isolada, sequência de aminoácidos, construção gênica, vetor, e, organismo
MXPA05008216A (es) * 2003-01-31 2005-10-05 Procter & Gamble Medios para mejorar la apariencia del tejido queratinoso mamifero.
US20050123500A1 (en) * 2003-01-31 2005-06-09 The Procter & Gamble Company Means for improving the appearance of mammalian hair and nails
US20040172682A1 (en) * 2003-02-12 2004-09-02 Kinney Anthony J. Production of very long chain polyunsaturated fatty acids in oilseed plants
US8084074B2 (en) * 2003-02-12 2011-12-27 E. I. Du Pont De Nemours And Company Production of very long chain polyunsaturated fatty acids in oil seed plants
BRPI0407138A (pt) 2003-02-27 2006-01-10 Basf Plant Science Gmbh Sequência de ácido nucleico isolada, sequência de aminoácido, construção de gene, vetor, organismo transgênico não humano, processo para produzir ácidos graxos poliinsaturados, óleo, lipìdeo, ou um ácido graxo poliinsaturado ou uma fração dos mesmos, composições de óleo, de lipìdeos, ou de ácido graxo, e, uso do óleo, lipìdeos ou ácidos graxos ou de composições de óleo, de lipìdeos ou de ácido graxo
ES2421138T3 (es) 2003-03-31 2013-08-29 University Of Bristol Nuevas aciltransferasas vegetales específicas para ácidos grasos poliinsaturados de cadena larga
BRPI0409209A (pt) 2003-04-08 2006-03-28 Basf Plant Science Gmbh seqüência de ácido nucleico isolado, construto de gene, vetor, organismo não-humano transgênico, processo para produzir ácidos graxos poliinsaturados, óleo, lipìdeos ou ácidos graxos ou uma fração dos mesmos, composição de óleo, de lipìdeo ou de ácido graxo, e, uso de óleo, de lipìdeos ou de ácidos graxos ou de composição de óleo, de lipìdeo ou de ácido graxo
US7214491B2 (en) 2003-05-07 2007-05-08 E. I. Du Pont De Nemours And Company Δ-12 desaturase gene suitable for altering levels of polyunsaturated fatty acids in oleaginous yeasts
US7125672B2 (en) * 2003-05-07 2006-10-24 E. I. Du Pont De Nemours And Company Codon-optimized genes for the production of polyunsaturated fatty acids in oleaginous yeasts
US7238482B2 (en) * 2003-05-07 2007-07-03 E. I. Du Pont De Nemours And Company Production of polyunsaturated fatty acids in oleaginous yeasts
GB0311081D0 (en) * 2003-05-14 2003-06-18 Btg Internat Limted Treatment of neurodegenerative conditions
EP2166069B2 (de) 2003-08-01 2024-01-24 BASF Plant Science GmbH Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren in transgenen Organismen
US11952581B2 (en) 2003-08-01 2024-04-09 Basf Plant Science Gmbh Process for the production of polyunsaturated fatty acids in transgenic organisms
DE112004001520B4 (de) * 2003-08-18 2008-04-10 Btg International Ltd. Verwendung eines Lipidglyzerids festgelegter Struktur zur Herstellung eines Medikamentes zur Behandlung der multiplen Sklerose
ES2323644T3 (es) * 2003-08-21 2009-07-22 Monsanto Technology Llc Desaturasas de acidos grasos procedentes de primula.
WO2005047480A2 (en) * 2003-11-12 2005-05-26 E.I. Dupont De Nemours And Company Delta-15 desaturases suitable for altering levels of polyunsaturated fatty acids in oleaginous plants and yeast
US7504259B2 (en) * 2003-11-12 2009-03-17 E. I. Du Pont De Nemours And Company Δ12 desaturases suitable for altering levels of polyunsaturated fatty acids in oleaginous yeast
CN1894405B (zh) * 2003-12-17 2011-02-02 三得利控股株式会社 含有花生四烯酸的植物体及其利用
WO2005083053A2 (de) 2004-02-27 2005-09-09 Basf Plant Science Gmbh Verfahren zur herstellung von ungesättigten omega-3-fettsäuren in transgenen organismen
JP4567047B2 (ja) 2004-02-27 2010-10-20 ビーエーエスエフ プラント サイエンス ゲーエムベーハー トランスジェニック植物における多価不飽和脂肪酸の製造方法
ES2541537T3 (es) 2004-04-16 2015-07-21 Monsanto Technology, Llc Expresión de desaturasas de ácido graso en maíz
BR122019013214B1 (pt) 2004-04-22 2022-04-12 Commonwealth Scientific And Industrial Research Organisation Polinucleotídeo isolado, vetor, célula recombinante, método para produzir uma célula recombinante, método para produzir um ou mais ácido graxo(s) poliinsaturado de cadeia longa, método para produzir uma semente transgênica, método para produzir óleo, método para produzir uma semente oleaginosa, extrato da semente transgênica, composição compreendendo o referido extrato, ração e uso da referida célula recombinante ou extrato
US7807849B2 (en) 2004-04-22 2010-10-05 Commonwealth Scientific And Industrial Research Organisation Synthesis of long-chain polyunsaturated fatty acids by recombinant cells
US7364883B2 (en) * 2004-05-07 2008-04-29 Yeastern Biotech Co., Ltd. Process for producing poly-unsaturated fatty acids by oleaginous yeasts
US20050266051A1 (en) * 2004-05-27 2005-12-01 The Procter & Gamble Company Pet food compositions and methods
PT1766023E (pt) 2004-06-04 2010-12-09 Fluxome Sciences As Células metabolicamente manipuladas para a produção de ácidos gordos poliinsaturados
WO2006012326A1 (en) 2004-06-25 2006-02-02 E.I. Dupont De Nemours And Company Delta-8 desaturase and its use in making polyunsaturated fatty acids
US7465564B2 (en) * 2004-08-10 2008-12-16 E.I. Du Pont De Nemours And Company Production of γ-linolenic acid in oleaginous yeast
US7456270B2 (en) * 2004-09-01 2008-11-25 Abbott Laboratories Δ6-desaturase genes and uses thereof
US7588931B2 (en) * 2004-11-04 2009-09-15 E. I. Du Pont De Nemours And Company High arachidonic acid producing strains of Yarrowia lipolytica
US8685679B2 (en) * 2004-11-04 2014-04-01 E I Du Pont De Nemours And Company Acyltransferase regulation to increase the percent of polyunsaturated fatty acids in total lipids and oils of oleaginous organisms
GB0425932D0 (en) * 2004-11-25 2004-12-29 Btg Int Ltd Structured phospholipids
CA2598792A1 (en) 2005-03-02 2006-09-08 Metanomics Gmbh Process for the production of fine chemicals
GB0504362D0 (en) * 2005-03-02 2005-04-06 Btg Int Ltd Cytokine modulators
GB0504333D0 (en) * 2005-03-02 2005-04-06 Btg Int Ltd Treatment of cytokine dysregulation
EP1866428A2 (en) * 2005-03-18 2007-12-19 Microbia, Inc. Production of carotenoids in oleaginous yeast and fungi
DE102005013779A1 (de) 2005-03-22 2006-09-28 Basf Plant Science Gmbh Verfahren zur Herstellung von mehrfach ungesättigten C20- und C22-Fettsäuren mit mindestens vier Doppelbindungen in transgenen Pflanzen
EP1714564A1 (en) * 2005-04-21 2006-10-25 N.V. Nutricia Method for treatment and prevention of respiratory insufficiency
EP1885862B1 (en) 2005-05-23 2015-07-29 Arcadia Biosciences Inc. Safflower with elevated gamma-linolenic acid
DE102005038036A1 (de) 2005-08-09 2007-02-15 Basf Plant Science Gmbh Verfahren zur Herstellung von Arachidonsäure und/oder Eicosapentaensäure in transgenen Nutzpflanzen
GB2431158A (en) 2005-10-13 2007-04-18 Rothamsted Res Ltd Process for the production of arachidonic and/or eicosapentaenoic acid
DE102005052551A1 (de) 2005-11-02 2007-05-16 Rothamsted Res Harpenden Verfahren zur Herstellung von y-Linolensäure und/oder Stearidonsäure in transgenen Brassicaceae und Linaceae
CA2625855C (en) 2005-11-23 2016-04-19 E. I. Du Pont De Nemours And Company Delta-9 elongases and their use in making polyunsaturated fatty acids
GB0603160D0 (en) 2006-02-16 2006-03-29 Rothamsted Res Ltd Nucleic acid
AR059376A1 (es) 2006-02-21 2008-03-26 Basf Plant Science Gmbh Procedimiento para la produccion de acidos grasos poliinsaturados
CN101437508A (zh) * 2006-03-03 2009-05-20 孟山都技术有限公司 用于改善心血管健康的十八碳四烯酸
US8629195B2 (en) 2006-04-08 2014-01-14 Bayer Materialscience Ag Production of polyurethane foams
US7943823B2 (en) * 2006-04-28 2011-05-17 E.I. Du Pont De Nemours And Company Delta-8 desaturase and its use in making polyunsaturated fatty acids
US7695950B2 (en) * 2006-05-17 2010-04-13 E. I. Du Pont De Nemours And Company Δ5 desaturase and its use in making polyunsaturated fatty acids
US7678560B2 (en) * 2006-05-17 2010-03-16 E.I. Du Pont De Nemours And Company Δ 5 desaturase and its use in making polyunsaturated fatty acids
EP2034983A1 (en) * 2006-06-27 2009-03-18 Lipid Nutrition B.V. Use of a polyunsaturated fatty acid compound
BRPI0714390B1 (pt) * 2006-07-19 2018-05-15 Monsanto Technology Llc Polinucleotídeo, construção de dna, célula hospedeira fúngica ou bacteriana, processo para produção de alimento ou de produto alimentício e composição para alimento ou produto alimentício
WO2008022963A2 (en) 2006-08-24 2008-02-28 Basf Plant Science Gmbh Isolation and characterization of a novel pythium omega 3 desaturase with specificity to all omega 6 fatty acids longer than 18 carbon chains
WO2008025068A1 (en) 2006-08-29 2008-03-06 Commonwealth Scientific And Industrial Research Organisation Synthesis of fatty acids
US8691555B2 (en) 2006-09-28 2014-04-08 Dsm Ip Assests B.V. Production of carotenoids in oleaginous yeast and fungi
ES2531391T3 (es) 2006-10-06 2015-03-13 Basf Plant Science Gmbh Delta-5 desaturasas y procedimiento para la preparación de ácidos grasos poliinsaturados en organismos transgénicos no humanos
PL2390339T3 (pl) 2006-10-23 2013-12-31 Du Pont Delta-8 desaturazy i ich zastosowanie w wytwarzaniu polinienasyconych kwasów tłuszczowych
WO2008100545A2 (en) 2007-02-12 2008-08-21 E. I. Du Pont De Nemours And Company Production of arachidonic acid in oilseed plants
RU2517608C2 (ru) * 2007-04-03 2014-05-27 Е.И.Дюпон Де Немур Энд Компани Мультизимы и их использование в получении полиненасыщенных жирных кислот
US8188338B2 (en) 2007-04-10 2012-05-29 E. I. Du Pont De Nemours And Company Delta-8 desaturases and their use in making polyunsaturated fatty acids
US7794701B2 (en) 2007-04-16 2010-09-14 E.I. Du Pont De Nemours And Company Δ-9 elongases and their use in making polyunsaturated fatty acids
US8957280B2 (en) 2007-05-03 2015-02-17 E. I. Du Pont De Nemours And Company Delta-5 desaturases and their use in making polyunsaturated fatty acids
CN101939434B (zh) 2007-05-24 2015-03-25 纳幕尔杜邦公司 用于在大豆中提高种子贮藏油脂的生成和改变脂肪酸谱的来自解脂耶氏酵母的dgat基因
CA2695112A1 (en) 2007-07-31 2009-02-05 Basf Plant Science Gmbh Elongases and processes for the production of polyunsaturated fatty acids in transgenic organisms
CA2701094A1 (en) 2007-10-03 2009-04-09 E. I. Du Pont De Nemours And Company Optimized strains of yarrowia lipolytica for high eicosapentaenoic acid production
EP2222856A2 (en) 2007-12-14 2010-09-01 BASF Plant Science GmbH Promoters from brassica napus for seed specific gene expression
WO2009133145A1 (en) 2008-04-30 2009-11-05 Basf Plant Science Gmbh Desaturase and method for the production of polyunsaturated fatty acids in transgenic organisms
EP2620500A3 (en) 2008-05-23 2014-01-08 E. I. du Pont de Nemours and Company DGAT genes from oleaginous organisms for increased seed storage lipid production and altered fatty acid profiles in oilseed plants
EP2318533A2 (en) 2008-07-01 2011-05-11 BASF Plant Science GmbH Promoters from brassica napus for seed specific gene expression
CA2732510C (en) * 2008-08-01 2018-03-13 E.I. Du Pont De Nemours And Company .delta.6 desaturases and their use in making polyunsaturated fatty acids
WO2010023202A2 (en) 2008-08-26 2010-03-04 Basf Plant Science Gmbh Nucleic acids encoding desaturases and modified plant oil
CA2743880C (en) * 2008-11-18 2020-08-18 James Robertson Petrie Recombinant cells comprising exogenous a5 elongase and methods for producing docosapentaenoic acid
AU2009326129B2 (en) 2008-12-12 2016-05-12 Basf Plant Science Gmbh Desaturases and process for the production of polyunsaturated fatty acids in transgenic organisms
US8060617B2 (en) * 2008-12-19 2011-11-15 Cisco Technology, Inc. Reserving network resources during scheduling of meeting event
AR074941A1 (es) 2009-01-07 2011-02-23 Bayer Cropscience Sa Plantas transplastomicas exentas de marcador de seleccion
CA2755027C (en) * 2009-04-01 2018-09-18 E. I. Du Pont De Nemours And Company Use of a seed specific promoter to drive odp1 expression in cruciferous oilseed plants to increase oil content while maintaining normal germination
AU2010247438B2 (en) 2009-05-13 2015-01-29 Basf Plant Science Company Gmbh Acyltransferases and uses thereof in fatty acid production
JP2013525549A (ja) 2010-04-22 2013-06-20 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー 微生物バイオマスから多価不飽和脂肪酸含有組成物を得る方法
WO2011161093A1 (en) 2010-06-25 2011-12-29 Basf Plant Science Company Gmbh Acyltransferases and uses therof in fatty acid production
US8658413B2 (en) 2010-08-26 2014-02-25 E I Du Pont De Nemours And Company Mutant HPGG motif and HDASH motif delta-5 desaturases and their use in making polyunsaturated fatty acids
MY162797A (en) 2010-12-29 2017-07-14 Abbott Lab Nutritional products including a novel fat system including monoglycerides
CN103649313B (zh) 2011-03-07 2017-10-24 Dsm营养产品股份公司 工程化破囊壶菌属微生物
US20120247066A1 (en) 2011-04-01 2012-10-04 Ice House America, Llc Ice bagging apparatus and methods
AU2012258820A1 (en) 2011-05-26 2013-10-10 E. I. Du Pont De Nemours And Company Expression of caleosin in recombinant oleaginous microorganisms to increase oil content therein
RU2014126356A (ru) * 2011-11-29 2016-01-27 Дигнити Сайенсиз Лимитед Композиции, содержащие жирные кислоты с цепью из 20 атомов углерода, и способы их получения и применения
BR112014015564B8 (pt) 2011-12-22 2022-11-08 Du Pont Construtos de dna recombinante e métodos de aumento do teor de óleo de sementes de soja
CA2869738C (en) 2012-04-12 2022-04-05 Rothamsted Research Ltd Production of omega-3 long chain polyunsaturated fatty acids
MY187101A (en) 2012-06-15 2021-08-31 Commw Scient Ind Res Org Production of long chain polyunsaturated fatty acids in plant cells
GB201217524D0 (en) 2012-10-01 2012-11-14 Rothamsted Res Ltd Recombinant organisms
CN105189740B (zh) 2013-03-13 2019-01-15 帝斯曼营养品股份公司 工程化微生物
LT3101138T (lt) * 2013-12-04 2021-07-26 Nippon Suisan Kaisha, Ltd. Mikrobinis aliejus, mikrobinio aliejaus gamybos būdas, koncentruotas mikrobinis aliejus, ir koncentruoto mikrobinio aliejaus gamybos būdas
UA122768C2 (uk) 2013-12-18 2021-01-06 Коммонвелз Сайнтіфік Енд Індастріал Рисерч Организейшн Екстрагований рослинний ліпід, що містить довголанцюгові поліненасичені жирні кислоти
AU2015281791A1 (en) 2014-06-27 2017-01-12 Commonwealth Scientific And Industrial Research Organisation Lipid comprising docosapentaenoic acid
CN104328145B (zh) * 2014-10-20 2017-05-17 南京大学 一种用基因工程大肠杆菌生产不饱和脂肪酸的方法
US10494642B2 (en) * 2015-04-28 2019-12-03 Basf Agricultural Solutions Seed, Us Llc Brassica plants with modified seed oil composition
AU2017322897B9 (en) * 2016-09-07 2022-06-09 Kao Corporation Method of producing lipid
US11197917B2 (en) 2017-12-01 2021-12-14 ByHeart, Inc. Formulations for nutritional support in subjects in need thereof
CN109837290B (zh) * 2019-04-03 2020-12-22 西南大学 ShFAD2基因家族和ShFAD3基因家族在创制高产ALA的转基因植物中的应用
CN110106019A (zh) * 2019-05-20 2019-08-09 无限极(中国)有限公司 一种利用裂壶藻生产复合型多不饱和脂肪酸油脂的方法
WO2023049921A1 (en) * 2021-09-27 2023-03-30 Kansas State University Research Foundation Pd-l1 inhibitory peptide for cancer immunotherapy
CN114807091A (zh) * 2022-04-14 2022-07-29 云南师范大学 一种耐热性提高的疏棉状嗜热丝孢菌脂肪酶及应用

Family Cites Families (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3649295A (en) * 1970-06-01 1972-03-14 American Home Prod Humanized fat compositions and infant formulas thereof
US4058594A (en) * 1974-04-25 1977-11-15 John Williams Immuno-suppressive agents
US4873191A (en) * 1981-06-12 1989-10-10 Ohio University Genetic transformation of zygotes
EP0092076B1 (fr) * 1982-04-16 1986-12-17 Societe Des Produits Nestle S.A. Composition lipidique destinée à l'alimentation orale, entérale ou parentérale
US4670285A (en) * 1982-08-06 1987-06-02 The University Of Toronto Innovations Foundation Infant formula
GB8317248D0 (en) * 1983-06-24 1983-07-27 Wyeth John & Brother Ltd Fat compositions
US4526902A (en) * 1983-10-24 1985-07-02 Century Laboratories, Inc. Combined fatty acid composition for treatment or prophylaxis of thrombo-embolic conditions
GB8407195D0 (en) * 1984-03-20 1984-04-26 Cadbury Schweppes Plc Microbial desaturase enzyme inhibitors
US4792523A (en) * 1984-08-31 1988-12-20 Cetus Corporation 3'Expression enhancing fragments and method
NL8403433A (nl) * 1984-11-09 1986-06-02 Holland Melkunie Voedingssuppletiepreparaat op basis van melkbestanddelen.
GB8507058D0 (en) * 1985-03-19 1985-04-24 Efamol Ltd Pharmaceutical & dietary compositions
GB2178752B (en) * 1985-07-12 1989-10-11 Unilever Plc Substitute milk fat
GB8524275D0 (en) * 1985-10-02 1985-11-06 Efamol Ltd Pharmaceutical & dietary compositions
GB8524276D0 (en) * 1985-10-02 1985-11-06 Efamol Ltd Pharmaceutical & dietary compositions
US5366894A (en) * 1986-06-30 1994-11-22 Pharmaceutical Proteins Limited Peptide production
US4920098A (en) * 1986-09-17 1990-04-24 Baxter International Inc. Nutritional support or therapy for individuals at risk or under treatment for atherosclerotic vascular, cardiovascular, and/or thrombotic diseases
US4921877A (en) * 1986-10-27 1990-05-01 Abbott Laboratories Liquid nutritional formula for glucose intolerance
EP0279582A3 (en) * 1987-02-17 1989-10-18 Pharming B.V. Dna sequences to target proteins to the mammary gland for efficient secretion
US5252333A (en) * 1987-04-27 1993-10-12 Scotia Holdings Plc Lithium salt-containing pharmaceutical compositions
DE3719097C1 (de) * 1987-06-06 1988-06-09 Fratzer Uwe Arzneimittel,enthaltend Eicosapentaensaeure und Docosahexaensaeure als ungesaettigte Fettsaeuren sowie Vitamin E
US4843095A (en) * 1987-08-07 1989-06-27 Century Laboratories, Inc. Free fatty acids for treatment or propyhlaxis of rheumatoid arthritis arthritis
US5011770A (en) * 1987-09-04 1991-04-30 Molecular Devices, Inc. DNA detection method
US5116871A (en) * 1988-09-13 1992-05-26 Efamol Holdings Plc Fatty acid therapy and compositions for the treatment of myalgic encephalomyelitis
US5162215A (en) * 1988-09-22 1992-11-10 Amgen Inc. Method of gene transfer into chickens and other avian species
US5057419A (en) 1988-09-22 1991-10-15 Rutgers University Genetically engineered plasmid and organisms for the production of specialized oils
US5196198A (en) * 1989-06-02 1993-03-23 Abbott Laboratories Parenteral nutrition product
US5426040A (en) * 1989-08-17 1995-06-20 Northeastern University Methods for producing improved strains of seaweed by fusion of spore-protoplasts, and resultant seaweeds and phycocolloids
US5407957A (en) * 1990-02-13 1995-04-18 Martek Corporation Production of docosahexaenoic acid by dinoflagellates
CA2077896C (en) 1990-03-16 2008-02-19 Gregory A. Thompson Plant desaturases - compositions and uses
US5512482A (en) * 1990-04-26 1996-04-30 Calgene, Inc. Plant thioesterases
CA2083259C (en) * 1990-05-25 2007-05-15 William D. Hitz Nucleotide sequence of soybean stearoyl-acp desaturase gene
ZA92452B (en) * 1991-01-24 1992-10-28 Martek Corp Microbial oil mixtures and uses thereof
US5658767A (en) 1991-01-24 1997-08-19 Martek Corporation Arachidonic acid and methods for the production and use thereof
WO1993004165A1 (en) * 1991-08-13 1993-03-04 Wisconsin Milk Marketing Board DNA SEQUENCE ENCODING BOVINE α-LACTALBUMIN AND METHODS OF USE
JPH0591886A (ja) * 1991-09-30 1993-04-16 Suntory Ltd 8,11−エイコサジエン酸及びこれを含有する脂質の製造方法
US6355861B1 (en) 1991-10-10 2002-03-12 Rhone-Poulenc Agrochimie Production of gamma linolenic acid by a Δ6-desaturase
US5614393A (en) 1991-10-10 1997-03-25 Rhone-Poulenc Agrochimie Production of γ-linolenic acid by a Δ6-desaturase
US6683232B1 (en) 1991-10-10 2004-01-27 Rhone-Poulenc Agrochimie Production of γ linolenic acid by a Δ6-desaturase
PH31293A (en) 1991-10-10 1998-07-06 Rhone Poulenc Agrochimie Production of y-linolenic acid by a delta6-desaturage.
DK0616644T3 (da) 1991-12-04 2003-10-27 Du Pont Fedtsyredesaturase-gener fra planter
CA2084348A1 (en) 1991-12-31 1993-07-01 David F. Hildebrand Fatty acid alteration by a d9 desaturase in transgenic plant tissue
JPH0614667A (ja) * 1992-03-13 1994-01-25 Lubrizol Corp:The デサチュラーゼを使用しての植物油の改変
WO1994005782A1 (en) 1992-09-10 1994-03-17 Trustees Of Tufts College In vivo production of transgenic organ by introducing the transgene via lumen
JP3818540B2 (ja) 1992-11-17 2006-09-06 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー 植物由来のミクロソームデルタ−12脂肪酸デサチュラーゼおよび関連酵素の遺伝子
AU683027B2 (en) * 1993-01-27 1997-10-30 Scotia Holdings Plc Triglycerides
CA2150133A1 (en) * 1993-02-05 1994-08-18 Vincent Jean-Marie Armel Arondel Altered linolenic and linoleic acid content in plants
US5639645A (en) 1993-09-22 1997-06-17 Mitsubishi Corporation Recombinant Δ9 desaturase and a gene encoding the same
BR9408435A (pt) 1993-12-28 1997-08-05 Kirin Brewery Gene para dessaturase de ácido graxo vetor contendo o dito gene planta transformada com o dito gene e processo para criar a dita planta
US5639940A (en) 1994-03-03 1997-06-17 Pharmaceutical Proteins Ltd. Production of fibrinogen in transgenic animals
JPH09509847A (ja) 1994-03-09 1997-10-07 アボツト・ラボラトリーズ 人乳化乳
MX198456B (es) 1994-03-09 2000-09-05 Abbott Lab Animales trangenicos que producen oligosacaridos y glucoconjugados.
EP0779359B1 (en) 1994-08-24 2002-02-13 Meiji Milk Products Company Limited Method of culturing avian cells
US5545553A (en) * 1994-09-26 1996-08-13 The Rockefeller University Glycosyltransferases for biosynthesis of oligosaccharides, and genes encoding them
US6310194B1 (en) * 1994-09-26 2001-10-30 Carnegie Institution Of Washington Plant fatty acid hydroxylases
FR2726003B1 (fr) 1994-10-21 2002-10-18 Agronomique Inst Nat Rech Milieu de culture de cellules embryonnaires totipotentes aviaires, procede de culture de ces cellules, et cellules embryonnaires totipotentes aviaires
US5654402A (en) 1994-10-26 1997-08-05 Michigan State University Methods and compositions relating to plant Δ6 palmitoyl-acyl carrier protein desaturase
GB9508023D0 (en) 1995-04-20 1995-06-07 Scotia Holdings Plc Fatty acid derivatives
US6048557A (en) * 1996-03-26 2000-04-11 Dsm N.V. PUFA coated solid carrier particles for foodstuff
US6255505B1 (en) * 1996-03-28 2001-07-03 Gist-Brocades, B.V. Microbial polyunsaturated fatty acid containing oil from pasteurised biomass
US5972664A (en) 1997-04-11 1999-10-26 Abbott Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids
IL132148A0 (en) 1997-04-11 2001-03-19 Calgene Llc Methods and compositions for synthesis of long chain polyunsaturated fatty acids in plants
US5968809A (en) 1997-04-11 1999-10-19 Abbot Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids
US6051754A (en) 1997-04-11 2000-04-18 Abbott Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids in plants
US6075183A (en) 1997-04-11 2000-06-13 Abbott Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids in plants
US6459018B1 (en) * 1998-06-12 2002-10-01 Monsanto Technology Llc Polyunsaturated fatty acids in plants

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