BE904796A - Nouveaux derives du morphinane et de la morphine, leur preparation, leur application comme medicaments et les compositions pharmaceutiques les contenant. - Google Patents
Nouveaux derives du morphinane et de la morphine, leur preparation, leur application comme medicaments et les compositions pharmaceutiques les contenant.Info
- Publication number
- BE904796A BE904796A BE1/011493A BE1011493A BE904796A BE 904796 A BE904796 A BE 904796A BE 1/011493 A BE1/011493 A BE 1/011493A BE 1011493 A BE1011493 A BE 1011493A BE 904796 A BE904796 A BE 904796A
- Authority
- BE
- Belgium
- Prior art keywords
- morphinane
- medicaments
- novel
- preparation
- application
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/28—Morphinans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/08—Bridged systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Immunology (AREA)
- Child & Adolescent Psychology (AREA)
- Heart & Thoracic Surgery (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
Composés de formule ci-dessous, dans laquelle X et Y signifient l'hydrogène ou forment ensemble un groupe -O- et R1, R2, R3, R4 et R5 représentent des restes organiques variés. Ces composés peuvent etre utilisés comme médicaments.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3518525 | 1985-05-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
BE904796A true BE904796A (fr) | 1986-11-21 |
Family
ID=6271435
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE1/011493A BE904796A (fr) | 1985-05-23 | 1986-05-21 | Nouveaux derives du morphinane et de la morphine, leur preparation, leur application comme medicaments et les compositions pharmaceutiques les contenant. |
Country Status (18)
Country | Link |
---|---|
JP (1) | JPS61271275A (fr) |
AU (1) | AU594954B2 (fr) |
BE (1) | BE904796A (fr) |
DK (1) | DK240386A (fr) |
ES (1) | ES8802318A1 (fr) |
FI (1) | FI862124A (fr) |
FR (1) | FR2582309B1 (fr) |
GB (1) | GB2175898B (fr) |
GR (1) | GR861318B (fr) |
HU (1) | HU196376B (fr) |
IL (1) | IL78872A0 (fr) |
IT (1) | IT1203791B (fr) |
LU (1) | LU86435A1 (fr) |
NL (1) | NL8601188A (fr) |
NZ (1) | NZ216250A (fr) |
PH (1) | PH23341A (fr) |
SE (1) | SE8602308L (fr) |
ZA (1) | ZA863873B (fr) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4857533A (en) * | 1988-12-15 | 1989-08-15 | Baker Cummins Pharmaceuticals, Inc. | Method of treatment for autoimmune diseases |
US4863928A (en) * | 1989-01-04 | 1989-09-05 | Baker Cummins Pharmaceuticals, Inc. | Method of treatment for arthritic and inflammatory diseases |
US4923875A (en) * | 1989-07-10 | 1990-05-08 | Baker Cummins Pharmaceuticals, Inc. | Method for treatment of mast cell-mediated dermatologic disorders |
JP2906654B2 (ja) * | 1989-11-28 | 1999-06-21 | 東レ株式会社 | 免疫抑制剤及びその製造方法 |
US5057322A (en) * | 1990-08-10 | 1991-10-15 | Baker Cummins Dermatologicals, Inc. | Method of treating mast cell disease |
ES2121988T3 (es) | 1992-01-23 | 1998-12-16 | Toray Industries | Derivado de morfinano y uso medicinal. |
DE69414085T2 (de) * | 1993-07-19 | 1999-03-18 | Toray Industries | Wirkstoff zum schutze von gehirnzellen |
JP3843456B2 (ja) | 1993-07-23 | 2006-11-08 | 東レ株式会社 | モルヒナン誘導体および医薬用途 |
PL327943A1 (en) | 1996-01-10 | 1999-01-04 | Smithkline Beecham Spa | Condensed heterocyclic derivatives of morphonoide (ii) |
EP1327444B1 (fr) * | 1996-11-25 | 2005-03-23 | Toray Industries, Inc. | Agent antiprurigineux |
WO1999005146A1 (fr) * | 1997-07-25 | 1999-02-04 | Toray Industries, Inc. | Remedes contre l'hyponatremie |
US7501433B2 (en) | 2002-05-17 | 2009-03-10 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
US7923454B2 (en) | 2002-05-17 | 2011-04-12 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
EP2987788A1 (fr) | 2002-05-17 | 2016-02-24 | Taiwanj Pharmaceuticals Co., Ltd. | Composés opioïdes et de type opioïde et leurs utilisations |
JP4957489B2 (ja) * | 2002-10-09 | 2012-06-20 | 東レ株式会社 | 含窒素環状置換基を有するモルヒナン誘導体またはその薬理学的に許容される酸付加塩を含有する医薬 |
US8017622B2 (en) | 2003-05-16 | 2011-09-13 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
EP2252150B1 (fr) * | 2008-02-14 | 2018-04-11 | Alkermes, Inc. | Composés opioïdes sélectifs |
TW201434837A (zh) * | 2012-12-14 | 2014-09-16 | Purdue Pharma Lp | 螺環嗎啡喃及其用途 |
US8980906B2 (en) * | 2012-12-14 | 2015-03-17 | Purdue Pharma L.P. | Pyridonemorphinan analogs and biological activity on opioid receptors |
AR096851A1 (es) * | 2013-07-11 | 2016-02-03 | H Lundbeck As | Sales que no forman hidratos ni solvatos de nalmefeno |
WO2015192053A1 (fr) * | 2014-06-13 | 2015-12-17 | Purdue Pharma L.P. | Dérivés d'azamophinan et leur utilisation |
-
1986
- 1986-05-09 HU HU861934A patent/HU196376B/hu not_active IP Right Cessation
- 1986-05-12 NL NL8601188A patent/NL8601188A/nl not_active Application Discontinuation
- 1986-05-19 GB GB8612159A patent/GB2175898B/en not_active Expired
- 1986-05-19 PH PH33785A patent/PH23341A/en unknown
- 1986-05-21 NZ NZ216250A patent/NZ216250A/en unknown
- 1986-05-21 AU AU57637/86A patent/AU594954B2/en not_active Expired - Fee Related
- 1986-05-21 SE SE8602308A patent/SE8602308L/xx not_active Application Discontinuation
- 1986-05-21 GR GR861318A patent/GR861318B/el unknown
- 1986-05-21 BE BE1/011493A patent/BE904796A/fr not_active IP Right Cessation
- 1986-05-21 FI FI862124A patent/FI862124A/fi not_active Application Discontinuation
- 1986-05-21 IL IL78872A patent/IL78872A0/xx unknown
- 1986-05-21 ES ES555200A patent/ES8802318A1/es not_active Expired
- 1986-05-22 JP JP61118984A patent/JPS61271275A/ja active Pending
- 1986-05-22 LU LU86435A patent/LU86435A1/fr unknown
- 1986-05-22 DK DK240386A patent/DK240386A/da not_active Application Discontinuation
- 1986-05-23 IT IT48050/86A patent/IT1203791B/it active
- 1986-05-23 FR FR8607367A patent/FR2582309B1/fr not_active Expired
- 1986-05-23 ZA ZA863873A patent/ZA863873B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
SE8602308L (sv) | 1986-11-24 |
GB2175898B (en) | 1989-07-05 |
FI862124A0 (fi) | 1986-05-21 |
IL78872A0 (en) | 1986-09-30 |
IT1203791B (it) | 1989-02-23 |
GB8612159D0 (en) | 1986-06-25 |
DK240386D0 (da) | 1986-05-22 |
SE8602308D0 (sv) | 1986-05-21 |
AU5763786A (en) | 1986-11-27 |
JPS61271275A (ja) | 1986-12-01 |
HUT41737A (en) | 1987-05-28 |
DK240386A (da) | 1986-11-24 |
ES8802318A1 (es) | 1988-05-01 |
NL8601188A (nl) | 1986-12-16 |
LU86435A1 (fr) | 1986-12-05 |
GB2175898A (en) | 1986-12-10 |
PH23341A (en) | 1989-07-14 |
IT8648050A0 (it) | 1986-05-23 |
FI862124A (fi) | 1986-11-24 |
FR2582309A1 (fr) | 1986-11-28 |
ES555200A0 (es) | 1988-05-01 |
ZA863873B (en) | 1988-01-27 |
FR2582309B1 (fr) | 1989-08-18 |
HU196376B (en) | 1988-11-28 |
AU594954B2 (en) | 1990-03-22 |
GR861318B (en) | 1986-09-19 |
NZ216250A (en) | 1990-04-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RE | Patent lapsed |
Owner name: SANDOZ S.A. Effective date: 19900531 |