GB2175898B - Morphinan derivatives - Google Patents
Morphinan derivativesInfo
- Publication number
- GB2175898B GB2175898B GB8612159A GB8612159A GB2175898B GB 2175898 B GB2175898 B GB 2175898B GB 8612159 A GB8612159 A GB 8612159A GB 8612159 A GB8612159 A GB 8612159A GB 2175898 B GB2175898 B GB 2175898B
- Authority
- GB
- United Kingdom
- Prior art keywords
- morphinan derivatives
- morphinan
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/28—Morphinans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/08—Bridged systems
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Child & Adolescent Psychology (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3518525 | 1985-05-23 |
Publications (3)
Publication Number | Publication Date |
---|---|
GB8612159D0 GB8612159D0 (en) | 1986-06-25 |
GB2175898A GB2175898A (en) | 1986-12-10 |
GB2175898B true GB2175898B (en) | 1989-07-05 |
Family
ID=6271435
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB8612159A Expired GB2175898B (en) | 1985-05-23 | 1986-05-19 | Morphinan derivatives |
Country Status (18)
Country | Link |
---|---|
JP (1) | JPS61271275A (en) |
AU (1) | AU594954B2 (en) |
BE (1) | BE904796A (en) |
DK (1) | DK240386A (en) |
ES (1) | ES8802318A1 (en) |
FI (1) | FI862124A (en) |
FR (1) | FR2582309B1 (en) |
GB (1) | GB2175898B (en) |
GR (1) | GR861318B (en) |
HU (1) | HU196376B (en) |
IL (1) | IL78872A0 (en) |
IT (1) | IT1203791B (en) |
LU (1) | LU86435A1 (en) |
NL (1) | NL8601188A (en) |
NZ (1) | NZ216250A (en) |
PH (1) | PH23341A (en) |
SE (1) | SE8602308L (en) |
ZA (1) | ZA863873B (en) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4857533A (en) * | 1988-12-15 | 1989-08-15 | Baker Cummins Pharmaceuticals, Inc. | Method of treatment for autoimmune diseases |
US4863928A (en) * | 1989-01-04 | 1989-09-05 | Baker Cummins Pharmaceuticals, Inc. | Method of treatment for arthritic and inflammatory diseases |
US4923875A (en) * | 1989-07-10 | 1990-05-08 | Baker Cummins Pharmaceuticals, Inc. | Method for treatment of mast cell-mediated dermatologic disorders |
JP2906654B2 (en) * | 1989-11-28 | 1999-06-21 | 東レ株式会社 | Immunosuppressant and method for producing the same |
US5057322A (en) * | 1990-08-10 | 1991-10-15 | Baker Cummins Dermatologicals, Inc. | Method of treating mast cell disease |
JP2525552B2 (en) | 1992-01-23 | 1996-08-21 | 東レ株式会社 | Morphine derivative and pharmaceutical use |
EP0661283B1 (en) * | 1993-07-19 | 1998-10-21 | Toray Industries, Inc. | Brain cell protective |
NZ268969A (en) * | 1993-07-23 | 1997-06-24 | Toray Industries | Morphinan derivatives and pharmaceutical compositions |
AR005423A1 (en) | 1996-01-10 | 1999-06-23 | Smithkline Beecham Spa | MORPHINOID DERIVATIVES CONDENSED WITH HETERO CYCLES (II), THEIR USE AS A THERAPEUTIC SUBSTANCE AND TO PREPARE MEDICINES, PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM AND PROCEDURE TO PREPARE SUCH DERIVATIVES. |
EP1312361A1 (en) * | 1996-11-25 | 2003-05-21 | Toray Industries, Inc. | Antipruritic agent |
AU6117298A (en) * | 1997-07-25 | 1999-02-16 | Toray Industries, Inc. | Hyponatremia remedies |
US7501433B2 (en) | 2002-05-17 | 2009-03-10 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
WO2003097608A2 (en) | 2002-05-17 | 2003-11-27 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
US7923454B2 (en) | 2002-05-17 | 2011-04-12 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
JP4957489B2 (en) * | 2002-10-09 | 2012-06-20 | 東レ株式会社 | Pharmaceutical containing morphinan derivative having nitrogen-containing cyclic substituent or pharmacologically acceptable acid addition salt thereof |
US8017622B2 (en) | 2003-05-16 | 2011-09-13 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
AU2009214500B2 (en) * | 2008-02-14 | 2014-10-23 | Alkermes, Inc. | Selective opioid compounds |
US8980906B2 (en) * | 2012-12-14 | 2015-03-17 | Purdue Pharma L.P. | Pyridonemorphinan analogs and biological activity on opioid receptors |
JP6141444B2 (en) * | 2012-12-14 | 2017-06-07 | パーデュー、ファーマ、リミテッド、パートナーシップ | Spirocyclic morphinans and their use |
AR096851A1 (en) * | 2013-07-11 | 2016-02-03 | H Lundbeck As | SALTS THAT DO NOT FORM HYDRATS OR SOLVATOS DE NALMEFENO |
WO2015192053A1 (en) * | 2014-06-13 | 2015-12-17 | Purdue Pharma L.P. | Azamophinan derivatives and use thereof |
-
1986
- 1986-05-09 HU HU861934A patent/HU196376B/en not_active IP Right Cessation
- 1986-05-12 NL NL8601188A patent/NL8601188A/en not_active Application Discontinuation
- 1986-05-19 GB GB8612159A patent/GB2175898B/en not_active Expired
- 1986-05-19 PH PH33785A patent/PH23341A/en unknown
- 1986-05-21 NZ NZ216250A patent/NZ216250A/en unknown
- 1986-05-21 ES ES555200A patent/ES8802318A1/en not_active Expired
- 1986-05-21 GR GR861318A patent/GR861318B/en unknown
- 1986-05-21 FI FI862124A patent/FI862124A/en not_active Application Discontinuation
- 1986-05-21 AU AU57637/86A patent/AU594954B2/en not_active Expired - Fee Related
- 1986-05-21 SE SE8602308A patent/SE8602308L/en not_active Application Discontinuation
- 1986-05-21 BE BE1/011493A patent/BE904796A/en not_active IP Right Cessation
- 1986-05-21 IL IL78872A patent/IL78872A0/en unknown
- 1986-05-22 JP JP61118984A patent/JPS61271275A/en active Pending
- 1986-05-22 DK DK240386A patent/DK240386A/en not_active Application Discontinuation
- 1986-05-22 LU LU86435A patent/LU86435A1/en unknown
- 1986-05-23 FR FR8607367A patent/FR2582309B1/en not_active Expired
- 1986-05-23 ZA ZA863873A patent/ZA863873B/en unknown
- 1986-05-23 IT IT48050/86A patent/IT1203791B/en active
Also Published As
Publication number | Publication date |
---|---|
IT8648050A0 (en) | 1986-05-23 |
GB8612159D0 (en) | 1986-06-25 |
IL78872A0 (en) | 1986-09-30 |
LU86435A1 (en) | 1986-12-05 |
HU196376B (en) | 1988-11-28 |
JPS61271275A (en) | 1986-12-01 |
HUT41737A (en) | 1987-05-28 |
FR2582309B1 (en) | 1989-08-18 |
ZA863873B (en) | 1988-01-27 |
SE8602308D0 (en) | 1986-05-21 |
DK240386A (en) | 1986-11-24 |
PH23341A (en) | 1989-07-14 |
SE8602308L (en) | 1986-11-24 |
AU594954B2 (en) | 1990-03-22 |
FI862124A (en) | 1986-11-24 |
GB2175898A (en) | 1986-12-10 |
FR2582309A1 (en) | 1986-11-28 |
NL8601188A (en) | 1986-12-16 |
ES8802318A1 (en) | 1988-05-01 |
FI862124A0 (en) | 1986-05-21 |
AU5763786A (en) | 1986-11-27 |
ES555200A0 (en) | 1988-05-01 |
BE904796A (en) | 1986-11-21 |
GR861318B (en) | 1986-09-19 |
IT1203791B (en) | 1989-02-23 |
NZ216250A (en) | 1990-04-26 |
DK240386D0 (en) | 1986-05-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PCNP | Patent ceased through non-payment of renewal fee |