GB8612159D0 - Morphinane derivatives - Google Patents

Morphinane derivatives

Info

Publication number
GB8612159D0
GB8612159D0 GB868612159A GB8612159A GB8612159D0 GB 8612159 D0 GB8612159 D0 GB 8612159D0 GB 868612159 A GB868612159 A GB 868612159A GB 8612159 A GB8612159 A GB 8612159A GB 8612159 D0 GB8612159 D0 GB 8612159D0
Authority
GB
United Kingdom
Prior art keywords
morphinane derivatives
morphinane
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB868612159A
Other versions
GB2175898A (en
GB2175898B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of GB8612159D0 publication Critical patent/GB8612159D0/en
Publication of GB2175898A publication Critical patent/GB2175898A/en
Application granted granted Critical
Publication of GB2175898B publication Critical patent/GB2175898B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/28—Morphinans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/08—Bridged systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Obesity (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
GB8612159A 1985-05-23 1986-05-19 Morphinan derivatives Expired GB2175898B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3518525 1985-05-23

Publications (3)

Publication Number Publication Date
GB8612159D0 true GB8612159D0 (en) 1986-06-25
GB2175898A GB2175898A (en) 1986-12-10
GB2175898B GB2175898B (en) 1989-07-05

Family

ID=6271435

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8612159A Expired GB2175898B (en) 1985-05-23 1986-05-19 Morphinan derivatives

Country Status (18)

Country Link
JP (1) JPS61271275A (en)
AU (1) AU594954B2 (en)
BE (1) BE904796A (en)
DK (1) DK240386A (en)
ES (1) ES8802318A1 (en)
FI (1) FI862124A (en)
FR (1) FR2582309B1 (en)
GB (1) GB2175898B (en)
GR (1) GR861318B (en)
HU (1) HU196376B (en)
IL (1) IL78872A0 (en)
IT (1) IT1203791B (en)
LU (1) LU86435A1 (en)
NL (1) NL8601188A (en)
NZ (1) NZ216250A (en)
PH (1) PH23341A (en)
SE (1) SE8602308L (en)
ZA (1) ZA863873B (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4857533A (en) * 1988-12-15 1989-08-15 Baker Cummins Pharmaceuticals, Inc. Method of treatment for autoimmune diseases
US4863928A (en) * 1989-01-04 1989-09-05 Baker Cummins Pharmaceuticals, Inc. Method of treatment for arthritic and inflammatory diseases
US4923875A (en) * 1989-07-10 1990-05-08 Baker Cummins Pharmaceuticals, Inc. Method for treatment of mast cell-mediated dermatologic disorders
JP2906654B2 (en) * 1989-11-28 1999-06-21 東レ株式会社 Immunosuppressant and method for producing the same
US5057322A (en) * 1990-08-10 1991-10-15 Baker Cummins Dermatologicals, Inc. Method of treating mast cell disease
CA2105072C (en) * 1992-01-23 1998-07-28 Hiroshi Nagase Morphinan derivative and its pharmaceutical applications
DE69414085T2 (en) * 1993-07-19 1999-03-18 Toray Industries, Inc., Tokio/Tokyo ACTIVE SUBSTANCE TO PROTECT BRAIN CELLS
JP3843456B2 (en) * 1993-07-23 2006-11-08 東レ株式会社 Morphinan derivatives and pharmaceutical applications
PL327943A1 (en) 1996-01-10 1999-01-04 Smithkline Beecham Spa Condensed heterocyclic derivatives of morphonoide (ii)
DK0897726T3 (en) * 1996-11-25 2007-08-13 Toray Industries Antipruritic agent
AU6117298A (en) * 1997-07-25 1999-02-16 Toray Industries, Inc. Hyponatremia remedies
US7501433B2 (en) 2002-05-17 2009-03-10 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
US7923454B2 (en) 2002-05-17 2011-04-12 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
MXPA04011327A (en) 2002-05-17 2005-08-15 Jenken Biosciences Inc Opioid and opioid-like compounds and uses thereof.
JP4957489B2 (en) * 2002-10-09 2012-06-20 東レ株式会社 Pharmaceutical containing morphinan derivative having nitrogen-containing cyclic substituent or pharmacologically acceptable acid addition salt thereof
US8017622B2 (en) 2003-05-16 2011-09-13 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
ES2671897T3 (en) * 2008-02-14 2018-06-11 Alkermes, Inc. Selective opioid compounds
US8987287B2 (en) * 2012-12-14 2015-03-24 Purdue Pharma L.P. Spirocyclic morphinans and their use
ES2631197T3 (en) * 2012-12-14 2017-08-29 Purdue Pharma Lp Pyridonamorfinan analogs and biological activity on opioid receptors
AR096851A1 (en) * 2013-07-11 2016-02-03 H Lundbeck As SALTS THAT DO NOT FORM HYDRATS OR SOLVATOS DE NALMEFENO
US10202382B2 (en) * 2014-06-13 2019-02-12 Purdue Pharma L.P. Azamorphinan derivatives and use thereof

Also Published As

Publication number Publication date
ES555200A0 (en) 1988-05-01
ES8802318A1 (en) 1988-05-01
SE8602308D0 (en) 1986-05-21
HU196376B (en) 1988-11-28
PH23341A (en) 1989-07-14
AU5763786A (en) 1986-11-27
FR2582309A1 (en) 1986-11-28
NL8601188A (en) 1986-12-16
BE904796A (en) 1986-11-21
JPS61271275A (en) 1986-12-01
GB2175898A (en) 1986-12-10
ZA863873B (en) 1988-01-27
IT1203791B (en) 1989-02-23
IL78872A0 (en) 1986-09-30
IT8648050A0 (en) 1986-05-23
DK240386D0 (en) 1986-05-22
FI862124A (en) 1986-11-24
DK240386A (en) 1986-11-24
GB2175898B (en) 1989-07-05
FI862124A0 (en) 1986-05-21
AU594954B2 (en) 1990-03-22
SE8602308L (en) 1986-11-24
NZ216250A (en) 1990-04-26
LU86435A1 (en) 1986-12-05
GR861318B (en) 1986-09-19
HUT41737A (en) 1987-05-28
FR2582309B1 (en) 1989-08-18

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee