GR861318B - Morphinan derivatives - Google Patents

Morphinan derivatives

Info

Publication number
GR861318B
GR861318B GR861318A GR860101318A GR861318B GR 861318 B GR861318 B GR 861318B GR 861318 A GR861318 A GR 861318A GR 860101318 A GR860101318 A GR 860101318A GR 861318 B GR861318 B GR 861318B
Authority
GR
Greece
Prior art keywords
morphinan derivatives
morphinan
derivatives
Prior art date
Application number
GR861318A
Other languages
Greek (el)
Inventor
Revesz Dr Laszlo
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of GR861318B publication Critical patent/GR861318B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10Spiro-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22Bridged ring systems
    • C07D221/28Morphinans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D489/00Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/08Bridged systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
GR861318A 1985-05-23 1986-05-21 Morphinan derivatives GR861318B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3518525 1985-05-23

Publications (1)

Publication Number Publication Date
GR861318B true GR861318B (en) 1986-09-19

Family

ID=6271435

Family Applications (1)

Application Number Title Priority Date Filing Date
GR861318A GR861318B (en) 1985-05-23 1986-05-21 Morphinan derivatives

Country Status (18)

Country Link
JP (1) JPS61271275A (en)
AU (1) AU594954B2 (en)
BE (1) BE904796A (en)
DK (1) DK240386A (en)
ES (1) ES8802318A1 (en)
FI (1) FI862124A (en)
FR (1) FR2582309B1 (en)
GB (1) GB2175898B (en)
GR (1) GR861318B (en)
HU (1) HU196376B (en)
IL (1) IL78872A0 (en)
IT (1) IT1203791B (en)
LU (1) LU86435A1 (en)
NL (1) NL8601188A (en)
NZ (1) NZ216250A (en)
PH (1) PH23341A (en)
SE (1) SE8602308L (en)
ZA (1) ZA863873B (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4857533A (en) * 1988-12-15 1989-08-15 Baker Cummins Pharmaceuticals, Inc. Method of treatment for autoimmune diseases
US4863928A (en) * 1989-01-04 1989-09-05 Baker Cummins Pharmaceuticals, Inc. Method of treatment for arthritic and inflammatory diseases
US4923875A (en) * 1989-07-10 1990-05-08 Baker Cummins Pharmaceuticals, Inc. Method for treatment of mast cell-mediated dermatologic disorders
JP2906654B2 (en) * 1989-11-28 1999-06-21 東レ株式会社 Immunosuppressant and method for producing the same
US5057322A (en) * 1990-08-10 1991-10-15 Baker Cummins Dermatologicals, Inc. Method of treating mast cell disease
EP0577847B1 (en) 1992-01-23 1998-10-14 Toray Industries, Inc. Morphinan derivative and medicinal use
WO1995003307A1 (en) * 1993-07-19 1995-02-02 Toray Industries, Inc. Brain cell protective
AU686203B2 (en) * 1993-07-23 1998-02-05 Toray Industries, Inc. Morphinan derivative and medicinal use
TR199801348T2 (en) * 1996-01-10 1998-10-21 Smithkline Beecham S.P.A. Heterosyclic condensate morphinoid t�revleri (II).
CN1180844C (en) * 1996-11-25 2004-12-22 东丽株式会社 Antipruritic agent
AU6117298A (en) * 1997-07-25 1999-02-16 Toray Industries, Inc. Hyponatremia remedies
US7923454B2 (en) 2002-05-17 2011-04-12 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
JP5438250B2 (en) 2002-05-17 2014-03-12 ジェンケン バイオサイエンスィズ,インコーポレイテッド Opioids and opioid-like compounds and their use
US7501433B2 (en) 2002-05-17 2009-03-10 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
JP4957489B2 (en) * 2002-10-09 2012-06-20 東レ株式会社 Pharmaceutical containing morphinan derivative having nitrogen-containing cyclic substituent or pharmacologically acceptable acid addition salt thereof
US8017622B2 (en) 2003-05-16 2011-09-13 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
US8354534B2 (en) * 2008-02-14 2013-01-15 Alkermes, Inc. Selective opioid compounds
WO2014091295A1 (en) * 2012-12-14 2014-06-19 Purdue Pharma L.P. Pyridonemorphinan analogs and biological activity on opioid receptors
JP6141444B2 (en) * 2012-12-14 2017-06-07 パーデュー、ファーマ、リミテッド、パートナーシップ Spirocyclic morphinans and their use
AR096851A1 (en) * 2013-07-11 2016-02-03 H Lundbeck As SALTS THAT DO NOT FORM HYDRATS OR SOLVATOS DE NALMEFENO
WO2015192053A1 (en) * 2014-06-13 2015-12-17 Purdue Pharma L.P. Azamophinan derivatives and use thereof

Also Published As

Publication number Publication date
DK240386A (en) 1986-11-24
ZA863873B (en) 1988-01-27
SE8602308D0 (en) 1986-05-21
HUT41737A (en) 1987-05-28
FI862124A0 (en) 1986-05-21
ES8802318A1 (en) 1988-05-01
GB2175898B (en) 1989-07-05
BE904796A (en) 1986-11-21
JPS61271275A (en) 1986-12-01
IT8648050A0 (en) 1986-05-23
ES555200A0 (en) 1988-05-01
DK240386D0 (en) 1986-05-22
IL78872A0 (en) 1986-09-30
SE8602308L (en) 1986-11-24
IT1203791B (en) 1989-02-23
GB2175898A (en) 1986-12-10
PH23341A (en) 1989-07-14
FR2582309A1 (en) 1986-11-28
LU86435A1 (en) 1986-12-05
NZ216250A (en) 1990-04-26
FI862124A (en) 1986-11-24
FR2582309B1 (en) 1989-08-18
GB8612159D0 (en) 1986-06-25
NL8601188A (en) 1986-12-16
AU594954B2 (en) 1990-03-22
AU5763786A (en) 1986-11-27
HU196376B (en) 1988-11-28

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