IT8648050A0 - DERIVATIVES OF MORPHINAN AND MORPHINE, THEIR PREPARATION, THEIR USE AS MEDICINAL PRODUCTS AND THE PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM - Google Patents

DERIVATIVES OF MORPHINAN AND MORPHINE, THEIR PREPARATION, THEIR USE AS MEDICINAL PRODUCTS AND THE PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM

Info

Publication number
IT8648050A0
IT8648050A0 IT8648050A IT4805086A IT8648050A0 IT 8648050 A0 IT8648050 A0 IT 8648050A0 IT 8648050 A IT8648050 A IT 8648050A IT 4805086 A IT4805086 A IT 4805086A IT 8648050 A0 IT8648050 A0 IT 8648050A0
Authority
IT
Italy
Prior art keywords
morphinan
morphine
derivatives
contain
preparation
Prior art date
Application number
IT8648050A
Other languages
Italian (it)
Other versions
IT1203791B (en
Inventor
Revesz Laszlo
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of IT8648050A0 publication Critical patent/IT8648050A0/en
Application granted granted Critical
Publication of IT1203791B publication Critical patent/IT1203791B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/28—Morphinans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/08—Bridged systems
IT48050/86A 1985-05-23 1986-05-23 DERIVATIVES OF MORFINANO AND MORFINA, THEIR PREPARATION, THEIR USE AS MEDICATIONS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM IT1203791B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3518525 1985-05-23

Publications (2)

Publication Number Publication Date
IT8648050A0 true IT8648050A0 (en) 1986-05-23
IT1203791B IT1203791B (en) 1989-02-23

Family

ID=6271435

Family Applications (1)

Application Number Title Priority Date Filing Date
IT48050/86A IT1203791B (en) 1985-05-23 1986-05-23 DERIVATIVES OF MORFINANO AND MORFINA, THEIR PREPARATION, THEIR USE AS MEDICATIONS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Country Status (18)

Country Link
JP (1) JPS61271275A (en)
AU (1) AU594954B2 (en)
BE (1) BE904796A (en)
DK (1) DK240386A (en)
ES (1) ES8802318A1 (en)
FI (1) FI862124A (en)
FR (1) FR2582309B1 (en)
GB (1) GB2175898B (en)
GR (1) GR861318B (en)
HU (1) HU196376B (en)
IL (1) IL78872A0 (en)
IT (1) IT1203791B (en)
LU (1) LU86435A1 (en)
NL (1) NL8601188A (en)
NZ (1) NZ216250A (en)
PH (1) PH23341A (en)
SE (1) SE8602308L (en)
ZA (1) ZA863873B (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4857533A (en) * 1988-12-15 1989-08-15 Baker Cummins Pharmaceuticals, Inc. Method of treatment for autoimmune diseases
US4863928A (en) * 1989-01-04 1989-09-05 Baker Cummins Pharmaceuticals, Inc. Method of treatment for arthritic and inflammatory diseases
US4923875A (en) * 1989-07-10 1990-05-08 Baker Cummins Pharmaceuticals, Inc. Method for treatment of mast cell-mediated dermatologic disorders
JP2906654B2 (en) * 1989-11-28 1999-06-21 東レ株式会社 Immunosuppressant and method for producing the same
US5057322A (en) * 1990-08-10 1991-10-15 Baker Cummins Dermatologicals, Inc. Method of treating mast cell disease
WO1993015081A1 (en) * 1992-01-23 1993-08-05 Toray Industries, Inc. Morphinan derivative and medicinal use
EP0661283B1 (en) * 1993-07-19 1998-10-21 Toray Industries, Inc. Brain cell protective
AU686203B2 (en) * 1993-07-23 1998-02-05 Toray Industries, Inc. Morphinan derivative and medicinal use
US6365594B1 (en) * 1996-01-10 2002-04-02 Smithkline Beecham S.P.A. Heterocycle-condensed morphinoid derivatives (II)
WO1998023290A1 (en) * 1996-11-25 1998-06-04 Toray Industries, Inc. Antipruritic agent
AU6117298A (en) * 1997-07-25 1999-02-16 Toray Industries, Inc. Hyponatremia remedies
US7923454B2 (en) 2002-05-17 2011-04-12 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
CA2486157C (en) 2002-05-17 2013-04-16 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
US7501433B2 (en) 2002-05-17 2009-03-10 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
JP4957489B2 (en) * 2002-10-09 2012-06-20 東レ株式会社 Pharmaceutical containing morphinan derivative having nitrogen-containing cyclic substituent or pharmacologically acceptable acid addition salt thereof
US8017622B2 (en) 2003-05-16 2011-09-13 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
AU2009214500B2 (en) * 2008-02-14 2014-10-23 Alkermes, Inc. Selective opioid compounds
CA2894967A1 (en) * 2012-12-14 2014-06-19 Purdue Pharma L.P. Spirocyclic morphinans and their use
EP2931724B1 (en) * 2012-12-14 2017-01-25 Purdue Pharma LP Pyridonemorphinan analogs and biological activity on opioid receptors
AR096851A1 (en) * 2013-07-11 2016-02-03 H Lundbeck As SALTS THAT DO NOT FORM HYDRATS OR SOLVATOS DE NALMEFENO
EP3154972A4 (en) * 2014-06-13 2017-11-22 Purdue Pharma L.P. Azamophinan derivatives and use thereof

Also Published As

Publication number Publication date
NL8601188A (en) 1986-12-16
SE8602308D0 (en) 1986-05-21
AU594954B2 (en) 1990-03-22
DK240386D0 (en) 1986-05-22
FR2582309A1 (en) 1986-11-28
ZA863873B (en) 1988-01-27
GR861318B (en) 1986-09-19
IL78872A0 (en) 1986-09-30
HU196376B (en) 1988-11-28
FI862124A0 (en) 1986-05-21
SE8602308L (en) 1986-11-24
JPS61271275A (en) 1986-12-01
NZ216250A (en) 1990-04-26
GB2175898B (en) 1989-07-05
FI862124A (en) 1986-11-24
GB8612159D0 (en) 1986-06-25
DK240386A (en) 1986-11-24
HUT41737A (en) 1987-05-28
GB2175898A (en) 1986-12-10
IT1203791B (en) 1989-02-23
PH23341A (en) 1989-07-14
BE904796A (en) 1986-11-21
FR2582309B1 (en) 1989-08-18
AU5763786A (en) 1986-11-27
ES8802318A1 (en) 1988-05-01
ES555200A0 (en) 1988-05-01
LU86435A1 (en) 1986-12-05

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