HUT41737A - Process for preparing morphinane derivatives and pharmaceutical compositions containing such compounds - Google Patents

Process for preparing morphinane derivatives and pharmaceutical compositions containing such compounds

Info

Publication number
HUT41737A
HUT41737A HU861934A HU193486A HUT41737A HU T41737 A HUT41737 A HU T41737A HU 861934 A HU861934 A HU 861934A HU 193486 A HU193486 A HU 193486A HU T41737 A HUT41737 A HU T41737A
Authority
HU
Hungary
Prior art keywords
preparing
compounds
pharmaceutical compositions
compositions containing
morphinane derivatives
Prior art date
Application number
HU861934A
Other languages
Hungarian (hu)
Other versions
HU196376B (en
Inventor
Laszlo Revesz
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of HUT41737A publication Critical patent/HUT41737A/en
Publication of HU196376B publication Critical patent/HU196376B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10Spiro-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22Bridged ring systems
    • C07D221/28Morphinans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D489/00Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/08Bridged systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
HU861934A 1985-05-23 1986-05-09 Process for preparing morphinane derivatives and pharmaceutical compositions containing such compounds HU196376B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3518525 1985-05-23

Publications (2)

Publication Number Publication Date
HUT41737A true HUT41737A (en) 1987-05-28
HU196376B HU196376B (en) 1988-11-28

Family

ID=6271435

Family Applications (1)

Application Number Title Priority Date Filing Date
HU861934A HU196376B (en) 1985-05-23 1986-05-09 Process for preparing morphinane derivatives and pharmaceutical compositions containing such compounds

Country Status (18)

Country Link
JP (1) JPS61271275A (en)
AU (1) AU594954B2 (en)
BE (1) BE904796A (en)
DK (1) DK240386A (en)
ES (1) ES8802318A1 (en)
FI (1) FI862124A (en)
FR (1) FR2582309B1 (en)
GB (1) GB2175898B (en)
GR (1) GR861318B (en)
HU (1) HU196376B (en)
IL (1) IL78872A0 (en)
IT (1) IT1203791B (en)
LU (1) LU86435A1 (en)
NL (1) NL8601188A (en)
NZ (1) NZ216250A (en)
PH (1) PH23341A (en)
SE (1) SE8602308L (en)
ZA (1) ZA863873B (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4857533A (en) * 1988-12-15 1989-08-15 Baker Cummins Pharmaceuticals, Inc. Method of treatment for autoimmune diseases
US4863928A (en) * 1989-01-04 1989-09-05 Baker Cummins Pharmaceuticals, Inc. Method of treatment for arthritic and inflammatory diseases
US4923875A (en) * 1989-07-10 1990-05-08 Baker Cummins Pharmaceuticals, Inc. Method for treatment of mast cell-mediated dermatologic disorders
JP2906654B2 (en) * 1989-11-28 1999-06-21 東レ株式会社 Immunosuppressant and method for producing the same
US5057322A (en) * 1990-08-10 1991-10-15 Baker Cummins Dermatologicals, Inc. Method of treating mast cell disease
EP0577847B1 (en) 1992-01-23 1998-10-14 Toray Industries, Inc. Morphinan derivative and medicinal use
WO1995003307A1 (en) * 1993-07-19 1995-02-02 Toray Industries, Inc. Brain cell protective
AU686203B2 (en) * 1993-07-23 1998-02-05 Toray Industries, Inc. Morphinan derivative and medicinal use
TR199801348T2 (en) * 1996-01-10 1998-10-21 Smithkline Beecham S.P.A. Heterosyclic condensate morphinoid t�revleri (II).
CN1180844C (en) * 1996-11-25 2004-12-22 东丽株式会社 Antipruritic agent
AU6117298A (en) * 1997-07-25 1999-02-16 Toray Industries, Inc. Hyponatremia remedies
US7923454B2 (en) 2002-05-17 2011-04-12 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
JP5438250B2 (en) 2002-05-17 2014-03-12 ジェンケン バイオサイエンスィズ,インコーポレイテッド Opioids and opioid-like compounds and their use
US7501433B2 (en) 2002-05-17 2009-03-10 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
JP4957489B2 (en) * 2002-10-09 2012-06-20 東レ株式会社 Pharmaceutical containing morphinan derivative having nitrogen-containing cyclic substituent or pharmacologically acceptable acid addition salt thereof
US8017622B2 (en) 2003-05-16 2011-09-13 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
US8354534B2 (en) * 2008-02-14 2013-01-15 Alkermes, Inc. Selective opioid compounds
WO2014091295A1 (en) * 2012-12-14 2014-06-19 Purdue Pharma L.P. Pyridonemorphinan analogs and biological activity on opioid receptors
JP6141444B2 (en) * 2012-12-14 2017-06-07 パーデュー、ファーマ、リミテッド、パートナーシップ Spirocyclic morphinans and their use
AR096851A1 (en) * 2013-07-11 2016-02-03 H Lundbeck As SALTS THAT DO NOT FORM HYDRATS OR SOLVATOS DE NALMEFENO
WO2015192053A1 (en) * 2014-06-13 2015-12-17 Purdue Pharma L.P. Azamophinan derivatives and use thereof

Also Published As

Publication number Publication date
DK240386A (en) 1986-11-24
ZA863873B (en) 1988-01-27
SE8602308D0 (en) 1986-05-21
FI862124A0 (en) 1986-05-21
ES8802318A1 (en) 1988-05-01
GB2175898B (en) 1989-07-05
BE904796A (en) 1986-11-21
GR861318B (en) 1986-09-19
JPS61271275A (en) 1986-12-01
IT8648050A0 (en) 1986-05-23
ES555200A0 (en) 1988-05-01
DK240386D0 (en) 1986-05-22
IL78872A0 (en) 1986-09-30
SE8602308L (en) 1986-11-24
IT1203791B (en) 1989-02-23
GB2175898A (en) 1986-12-10
PH23341A (en) 1989-07-14
FR2582309A1 (en) 1986-11-28
LU86435A1 (en) 1986-12-05
NZ216250A (en) 1990-04-26
FI862124A (en) 1986-11-24
FR2582309B1 (en) 1989-08-18
GB8612159D0 (en) 1986-06-25
NL8601188A (en) 1986-12-16
AU594954B2 (en) 1990-03-22
AU5763786A (en) 1986-11-27
HU196376B (en) 1988-11-28

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Legal Events

Date Code Title Description
HU90 Patent valid on 900628
HMM4 Cancellation of final prot. due to non-payment of fee