FR2416234A1 - Derives de metronidazole et compositions pharmaceutiques en contenant - Google Patents

Derives de metronidazole et compositions pharmaceutiques en contenant

Info

Publication number
FR2416234A1
FR2416234A1 FR7902950A FR7902950A FR2416234A1 FR 2416234 A1 FR2416234 A1 FR 2416234A1 FR 7902950 A FR7902950 A FR 7902950A FR 7902950 A FR7902950 A FR 7902950A FR 2416234 A1 FR2416234 A1 FR 2416234A1
Authority
FR
France
Prior art keywords
pharmaceutical compositions
compositions containing
metronidazole
derivatives
metronidazole derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7902950A
Other languages
English (en)
Other versions
FR2416234B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of FR2416234A1 publication Critical patent/FR2416234A1/fr
Application granted granted Critical
Publication of FR2416234B1 publication Critical patent/FR2416234B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6503—Five-membered rings
    • C07F9/6506—Five-membered rings having the nitrogen atoms in positions 1 and 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

Abstract

L'invention est relative à de nouveaux dérivés de métronidazole et à leur préparation. Les nouveaux composés répondent à la formule :
FR7902950A 1978-02-06 1979-02-05 Derives de metronidazole et compositions pharmaceutiques en contenant Granted FR2416234A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/875,393 US4160827A (en) 1978-02-06 1978-02-06 Metronidazole phosphate and salts

Publications (2)

Publication Number Publication Date
FR2416234A1 true FR2416234A1 (fr) 1979-08-31
FR2416234B1 FR2416234B1 (fr) 1983-02-04

Family

ID=25365724

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7902950A Granted FR2416234A1 (fr) 1978-02-06 1979-02-05 Derives de metronidazole et compositions pharmaceutiques en contenant

Country Status (16)

Country Link
US (1) US4160827A (fr)
JP (1) JPS54115375A (fr)
AU (1) AU523423B2 (fr)
BE (1) BE873973A (fr)
CA (1) CA1108622A (fr)
CH (1) CH638535A5 (fr)
DE (1) DE2903269A1 (fr)
ES (1) ES477265A1 (fr)
FR (1) FR2416234A1 (fr)
GB (1) GB2013683B (fr)
GR (1) GR67623B (fr)
IT (1) IT1116516B (fr)
NL (1) NL7900858A (fr)
PH (1) PH14464A (fr)
SE (1) SE445221B (fr)
ZA (1) ZA79282B (fr)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4386079A (en) * 1981-11-23 1983-05-31 The Upjohn Company Method of treating depression
US4531004A (en) * 1981-11-23 1985-07-23 The Upjohn Company Dimetronidazole phosphates
US5059591B1 (en) * 1983-05-26 2000-04-25 Liposome Co Inc Drug preparations of reduced toxicity
CA1237670A (fr) * 1983-05-26 1988-06-07 Andrew S. Janoff Reduction de la toxicite de certains medicaments
PT78628B (en) * 1984-05-02 1986-06-18 Liposome Co Inc Pharmaceutical composition with reduced toxicity
US4943579A (en) * 1987-10-06 1990-07-24 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Water soluble prodrugs of camptothecin
US7223421B2 (en) * 2000-06-30 2007-05-29 Mcneil-Ppc, Inc. Teste masked pharmaceutical particles
US8512718B2 (en) 2000-07-03 2013-08-20 Foamix Ltd. Pharmaceutical composition for topical application
US6423707B1 (en) 2000-08-28 2002-07-23 California Pacific Medical Center Nitroimidazole ester analogues and therapeutic applications
US20030055107A1 (en) * 2001-03-27 2003-03-20 Xu Xinmin Samuel Forms of pharmaceutically active agents and method for manufacture thereof
IL152486A0 (en) 2002-10-25 2003-05-29 Meir Eini Alcohol-free cosmetic and pharmaceutical foam carrier
US7700076B2 (en) 2002-10-25 2010-04-20 Foamix, Ltd. Penetrating pharmaceutical foam
NZ540166A (en) 2002-10-25 2007-06-29 Foamix Ltd Cosmetic and pharmaceutical foam
US10117812B2 (en) 2002-10-25 2018-11-06 Foamix Pharmaceuticals Ltd. Foamable composition combining a polar solvent and a hydrophobic carrier
US9265725B2 (en) 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
US8486376B2 (en) 2002-10-25 2013-07-16 Foamix Ltd. Moisturizing foam containing lanolin
US8119150B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Non-flammable insecticide composition and uses thereof
US7820145B2 (en) 2003-08-04 2010-10-26 Foamix Ltd. Oleaginous pharmaceutical and cosmetic foam
US9211259B2 (en) 2002-11-29 2015-12-15 Foamix Pharmaceuticals Ltd. Antibiotic kit and composition and uses thereof
US9668972B2 (en) 2002-10-25 2017-06-06 Foamix Pharmaceuticals Ltd. Nonsteroidal immunomodulating kit and composition and uses thereof
US8119109B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Foamable compositions, kits and methods for hyperhidrosis
US8900554B2 (en) 2002-10-25 2014-12-02 Foamix Pharmaceuticals Ltd. Foamable composition and uses thereof
US7704518B2 (en) 2003-08-04 2010-04-27 Foamix, Ltd. Foamable vehicle and pharmaceutical compositions thereof
US20080138296A1 (en) 2002-10-25 2008-06-12 Foamix Ltd. Foam prepared from nanoemulsions and uses
US7575739B2 (en) 2003-04-28 2009-08-18 Foamix Ltd. Foamable iodine composition
GB0315671D0 (en) * 2003-07-04 2003-08-13 Chelsea And Westminster Nhs Tr Improvements in or relating to organic compounds
US8795693B2 (en) 2003-08-04 2014-08-05 Foamix Ltd. Compositions with modulating agents
US8486374B2 (en) 2003-08-04 2013-07-16 Foamix Ltd. Hydrophilic, non-aqueous pharmaceutical carriers and compositions and uses
DE602004017214D1 (de) * 2003-10-28 2008-11-27 Ems Sa Antibakterielle und/oder gegen protozoen wirksame nitroimidazolderivatverbindungen mit ureasehemmender wirkung, verfahren zur herstellung dieser verbindungen und deren verwendung in pharmazeutischen zusammensetzungen und medikamenten
MX2007014101A (es) 2005-05-09 2009-02-13 Foamix Ltd Vehiculo espumable y composiciones farmaceuticas del mismo.
US20080260655A1 (en) 2006-11-14 2008-10-23 Dov Tamarkin Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses
US8636982B2 (en) 2007-08-07 2014-01-28 Foamix Ltd. Wax foamable vehicle and pharmaceutical compositions thereof
US9439857B2 (en) 2007-11-30 2016-09-13 Foamix Pharmaceuticals Ltd. Foam containing benzoyl peroxide
WO2009090495A2 (fr) 2007-12-07 2009-07-23 Foamix Ltd. Vecteurs moussants siliconés à base d'huile et de liquide, et formulations
WO2010041141A2 (fr) 2008-10-07 2010-04-15 Foamix Ltd. Support expansible à base d’huile et préparations
CA2712120A1 (fr) 2008-01-14 2009-07-23 Foamix Ltd. Compositions pharmaceutiques pouvant mousser de poloxamere avec des agents actifs et/ou des cellules therapeutiques, et utilisations
CA2760186C (fr) 2009-04-28 2019-10-29 Foamix Ltd. Vehicule moussant et compositions pharmaceutiques comportant des solvants polaires aprotiques et leurs utilisations
CA2769677A1 (fr) 2009-07-29 2011-02-03 Foamix Ltd. Compositions hydro-alcooliques moussantes a base d'agents non tensioactifs non polymeres, mousses legeres, et leurs utilisations
WO2011013009A2 (fr) 2009-07-29 2011-02-03 Foamix Ltd. Compositions hydro-alcooliques moussantes non tensioactives, mousses légères, et leurs utilisations
US9849142B2 (en) 2009-10-02 2017-12-26 Foamix Pharmaceuticals Ltd. Methods for accelerated return of skin integrity and for the treatment of impetigo
BR112012007473A2 (pt) 2009-10-02 2019-05-07 Foamix Ltd composições tópicas de tetraciclina e respectivo método de uso
CN102516298A (zh) * 2011-12-09 2012-06-27 陕西合成药业有限公司 左旋奥硝唑磷酸酯稳定的药用盐及其制备方法和用途
CN102516299A (zh) * 2011-12-09 2012-06-27 陕西合成药业有限公司 左旋奥硝唑磷酸酯氨基酸盐及其制备方法和用途
CA2978573A1 (fr) 2016-09-08 2018-03-08 Foamix Pharmaceuticals Ltd. Compositions et methodes de traitement de la rosacee et de l'acnee
CN108295039A (zh) * 2018-02-28 2018-07-20 重庆希尔安药业有限公司 甲硝唑阴道泡腾片及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE571291A (fr) * 1957-09-20 1962-01-12 Rhone Poulenc Sa Nouveaux derives de l'imidazole et leur preparation.
US2944061A (en) * 1957-09-20 1960-07-05 Acyl derivatives and process
GB1280355A (en) * 1969-06-20 1972-07-05 Rech S Et D Applic Scient Et M Substituted 5-nitro-imidazoles and their preparation
FR2054504B1 (fr) * 1969-07-18 1973-06-08 Rhone Poulenc Sa
US3910945A (en) * 1972-10-04 1975-10-07 Searle & Co 2-(2-Methyl-5-nitro-1-imidazolyl)ethyl-N-arylalkyldithiocarbamates
US3882136A (en) * 1973-11-16 1975-05-06 Searle & Co S-{8 omega-(1-imidazolyl) alkyl{9 hydrogen monothiosulfates and salts thereof

Also Published As

Publication number Publication date
AU4370579A (en) 1979-08-16
BE873973A (fr) 1979-08-06
SE445221B (sv) 1986-06-09
IT1116516B (it) 1986-02-10
CH638535A5 (de) 1983-09-30
AU523423B2 (en) 1982-07-29
CA1108622A (fr) 1981-09-08
ZA79282B (en) 1980-01-30
GR67623B (fr) 1981-09-01
IT7947874A0 (it) 1979-02-02
GB2013683A (en) 1979-08-15
PH14464A (en) 1981-07-29
SE7900952L (sv) 1979-08-07
NL7900858A (nl) 1979-08-08
JPS54115375A (en) 1979-09-07
GB2013683B (en) 1982-06-30
DE2903269A1 (de) 1979-08-09
FR2416234B1 (fr) 1983-02-04
US4160827A (en) 1979-07-10
ES477265A1 (es) 1980-10-01

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Legal Events

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ST Notification of lapse