ZA79282B - Metronidazole phosphate and salts - Google Patents

Metronidazole phosphate and salts

Info

Publication number
ZA79282B
ZA79282B ZA79282A ZA79282A ZA79282B ZA 79282 B ZA79282 B ZA 79282B ZA 79282 A ZA79282 A ZA 79282A ZA 79282 A ZA79282 A ZA 79282A ZA 79282 B ZA79282 B ZA 79282B
Authority
ZA
South Africa
Prior art keywords
salts
metronidazole phosphate
metronidazole
phosphate
Prior art date
Application number
ZA79282A
Other languages
English (en)
Inventor
J Biermacher
M Cho
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of ZA79282B publication Critical patent/ZA79282B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6503—Five-membered rings
    • C07F9/6506—Five-membered rings having the nitrogen atoms in positions 1 and 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA79282A 1978-02-06 1979-01-23 Metronidazole phosphate and salts ZA79282B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/875,393 US4160827A (en) 1978-02-06 1978-02-06 Metronidazole phosphate and salts

Publications (1)

Publication Number Publication Date
ZA79282B true ZA79282B (en) 1980-01-30

Family

ID=25365724

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA79282A ZA79282B (en) 1978-02-06 1979-01-23 Metronidazole phosphate and salts

Country Status (16)

Country Link
US (1) US4160827A (xx)
JP (1) JPS54115375A (xx)
AU (1) AU523423B2 (xx)
BE (1) BE873973A (xx)
CA (1) CA1108622A (xx)
CH (1) CH638535A5 (xx)
DE (1) DE2903269A1 (xx)
ES (1) ES477265A1 (xx)
FR (1) FR2416234A1 (xx)
GB (1) GB2013683B (xx)
GR (1) GR67623B (xx)
IT (1) IT1116516B (xx)
NL (1) NL7900858A (xx)
PH (1) PH14464A (xx)
SE (1) SE445221B (xx)
ZA (1) ZA79282B (xx)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4386079A (en) * 1981-11-23 1983-05-31 The Upjohn Company Method of treating depression
US4531004A (en) * 1981-11-23 1985-07-23 The Upjohn Company Dimetronidazole phosphates
CA1237670A (en) * 1983-05-26 1988-06-07 Andrew S. Janoff Drug preparations of reduced toxicity
US5059591B1 (en) * 1983-05-26 2000-04-25 Liposome Co Inc Drug preparations of reduced toxicity
PT78628B (en) * 1984-05-02 1986-06-18 Liposome Co Inc Pharmaceutical composition with reduced toxicity
US4943579A (en) * 1987-10-06 1990-07-24 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Water soluble prodrugs of camptothecin
US7223421B2 (en) * 2000-06-30 2007-05-29 Mcneil-Ppc, Inc. Teste masked pharmaceutical particles
US8512718B2 (en) 2000-07-03 2013-08-20 Foamix Ltd. Pharmaceutical composition for topical application
US6423707B1 (en) 2000-08-28 2002-07-23 California Pacific Medical Center Nitroimidazole ester analogues and therapeutic applications
CA2410469A1 (en) * 2001-03-27 2002-10-03 R.P. Scherer Technologies, Inc. Improved forms of pharmaceutically active agents and method for manufacture thereof
IL152486A0 (en) 2002-10-25 2003-05-29 Meir Eini Alcohol-free cosmetic and pharmaceutical foam carrier
US7700076B2 (en) 2002-10-25 2010-04-20 Foamix, Ltd. Penetrating pharmaceutical foam
US7820145B2 (en) 2003-08-04 2010-10-26 Foamix Ltd. Oleaginous pharmaceutical and cosmetic foam
US8900554B2 (en) 2002-10-25 2014-12-02 Foamix Pharmaceuticals Ltd. Foamable composition and uses thereof
US9265725B2 (en) 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
US9668972B2 (en) 2002-10-25 2017-06-06 Foamix Pharmaceuticals Ltd. Nonsteroidal immunomodulating kit and composition and uses thereof
US8119109B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Foamable compositions, kits and methods for hyperhidrosis
AU2003279493B2 (en) 2002-10-25 2009-08-20 Foamix Pharmaceuticals Ltd. Cosmetic and pharmaceutical foam
US8119150B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Non-flammable insecticide composition and uses thereof
US10117812B2 (en) 2002-10-25 2018-11-06 Foamix Pharmaceuticals Ltd. Foamable composition combining a polar solvent and a hydrophobic carrier
US7704518B2 (en) 2003-08-04 2010-04-27 Foamix, Ltd. Foamable vehicle and pharmaceutical compositions thereof
US20080138296A1 (en) 2002-10-25 2008-06-12 Foamix Ltd. Foam prepared from nanoemulsions and uses
US9211259B2 (en) 2002-11-29 2015-12-15 Foamix Pharmaceuticals Ltd. Antibiotic kit and composition and uses thereof
US8486376B2 (en) 2002-10-25 2013-07-16 Foamix Ltd. Moisturizing foam containing lanolin
US7575739B2 (en) 2003-04-28 2009-08-18 Foamix Ltd. Foamable iodine composition
GB0315671D0 (en) * 2003-07-04 2003-08-13 Chelsea And Westminster Nhs Tr Improvements in or relating to organic compounds
US8795693B2 (en) 2003-08-04 2014-08-05 Foamix Ltd. Compositions with modulating agents
US8486374B2 (en) 2003-08-04 2013-07-16 Foamix Ltd. Hydrophilic, non-aqueous pharmaceutical carriers and compositions and uses
EP1685114B1 (en) * 2003-10-28 2008-10-15 Ems S.A. Antibacterial and/or antiprotozoal nitroimidazole derivative compounds with urease inhibitor activity, process for preparing these compounds and use in pharmaceutical compositions and medicines.
JP2008540508A (ja) 2005-05-09 2008-11-20 フォーミックス エルティーディー． 起泡性ビヒクル及びその医薬組成物
US20080260655A1 (en) 2006-11-14 2008-10-23 Dov Tamarkin Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses
US8636982B2 (en) 2007-08-07 2014-01-28 Foamix Ltd. Wax foamable vehicle and pharmaceutical compositions thereof
WO2009069006A2 (en) 2007-11-30 2009-06-04 Foamix Ltd. Foam containing benzoyl peroxide
WO2009072007A2 (en) 2007-12-07 2009-06-11 Foamix Ltd. Carriers, formulations, methods for formulating unstable active agents for external application and uses thereof
WO2010041141A2 (en) 2008-10-07 2010-04-15 Foamix Ltd. Oil-based foamable carriers and formulations
WO2009090558A2 (en) 2008-01-14 2009-07-23 Foamix Ltd. Poloxamer foamable pharmaceutical compositions with active agents and/or therapeutic cells and uses
US20120087872A1 (en) 2009-04-28 2012-04-12 Foamix Ltd. Foamable Vehicles and Pharmaceutical Compositions Comprising Aprotic Polar Solvents and Uses Thereof
CA2769625C (en) 2009-07-29 2017-04-11 Foamix Ltd. Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses
WO2011013008A2 (en) 2009-07-29 2011-02-03 Foamix Ltd. Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses
US9849142B2 (en) 2009-10-02 2017-12-26 Foamix Pharmaceuticals Ltd. Methods for accelerated return of skin integrity and for the treatment of impetigo
CN102686205A (zh) 2009-10-02 2012-09-19 弗艾米克斯有限公司 局部四环素组合物
CN102516299A (zh) * 2011-12-09 2012-06-27 陕西合成药业有限公司 左旋奥硝唑磷酸酯氨基酸盐及其制备方法和用途
CN102516298A (zh) * 2011-12-09 2012-06-27 陕西合成药业有限公司 左旋奥硝唑磷酸酯稳定的药用盐及其制备方法和用途
MX2017011630A (es) 2016-09-08 2018-09-25 Foamix Pharmaceuticals Ltd Composiciones y metodos para tratar rosacea y acne.
CN108295039A (zh) * 2018-02-28 2018-07-20 重庆希尔安药业有限公司 甲硝唑阴道泡腾片及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2944061A (en) * 1957-09-20 1960-07-05 Acyl derivatives and process
BE571291A (fr) * 1957-09-20 1962-01-12 Rhone Poulenc Sa Nouveaux derives de l'imidazole et leur preparation.
GB1280355A (en) * 1969-06-20 1972-07-05 Rech S Et D Applic Scient Et M Substituted 5-nitro-imidazoles and their preparation
FR2054504B1 (xx) * 1969-07-18 1973-06-08 Rhone Poulenc Sa
US3910945A (en) * 1972-10-04 1975-10-07 Searle & Co 2-(2-Methyl-5-nitro-1-imidazolyl)ethyl-N-arylalkyldithiocarbamates
US3882136A (en) * 1973-11-16 1975-05-06 Searle & Co S-{8 omega-(1-imidazolyl) alkyl{9 hydrogen monothiosulfates and salts thereof

Also Published As

Publication number Publication date
DE2903269A1 (de) 1979-08-09
GB2013683A (en) 1979-08-15
US4160827A (en) 1979-07-10
IT7947874A0 (it) 1979-02-02
GR67623B (xx) 1981-09-01
SE445221B (sv) 1986-06-09
AU4370579A (en) 1979-08-16
JPS54115375A (en) 1979-09-07
FR2416234A1 (fr) 1979-08-31
FR2416234B1 (xx) 1983-02-04
ES477265A1 (es) 1980-10-01
PH14464A (en) 1981-07-29
IT1116516B (it) 1986-02-10
CA1108622A (en) 1981-09-08
SE7900952L (sv) 1979-08-07
AU523423B2 (en) 1982-07-29
GB2013683B (en) 1982-06-30
NL7900858A (nl) 1979-08-08
BE873973A (fr) 1979-08-06
CH638535A5 (de) 1983-09-30

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