BE855617A - Procede de fabrication de nouveaux gona-4,9(10)-dienes - Google Patents

Procede de fabrication de nouveaux gona-4,9(10)-dienes

Info

Publication number
BE855617A
BE855617A BE178379A BE178379A BE855617A BE 855617 A BE855617 A BE 855617A BE 178379 A BE178379 A BE 178379A BE 178379 A BE178379 A BE 178379A BE 855617 A BE855617 A BE 855617A
Authority
BE
Belgium
Prior art keywords
gona
dienes
manufacturing new
manufacturing
new
Prior art date
Application number
BE178379A
Other languages
English (en)
French (fr)
Inventor
K Ponsold
M Hubner
M Oettel
Original Assignee
Jenapharm Veb
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DD7600193348A external-priority patent/DD132497A1/de
Application filed by Jenapharm Veb filed Critical Jenapharm Veb
Publication of BE855617A publication Critical patent/BE855617A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051Estrane derivatives
    • C07J1/0081Substituted in position 17 alfa and 17 beta
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0044Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an estrane or gonane skeleton, including 18-substituted derivatives and derivatives where position 17-beta is substituted by a carbon atom not directly bonded to another carbon atom and not being part of an amide group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0094Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
BE178379A 1976-06-14 1977-06-13 Procede de fabrication de nouveaux gona-4,9(10)-dienes BE855617A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DD7600193348A DD132497A1 (de) 1976-06-14 1976-06-14 Verfahren zur herstellung von neuen gona-4,9(10)-dienen

Publications (1)

Publication Number Publication Date
BE855617A true BE855617A (fr) 1977-12-13

Family

ID=5504816

Family Applications (1)

Application Number Title Priority Date Filing Date
BE178379A BE855617A (fr) 1976-06-14 1977-06-13 Procede de fabrication de nouveaux gona-4,9(10)-dienes

Country Status (18)

Country Link
US (1) US4248790A (de)
JP (1) JPS5312849A (de)
BE (1) BE855617A (de)
BR (1) BR7703832A (de)
CH (1) CH635594A5 (de)
DE (1) DE2718872A1 (de)
DK (1) DK259477A (de)
ES (1) ES461987A3 (de)
FI (1) FI57113C (de)
FR (1) FR2393008A1 (de)
GB (1) GB1524917A (de)
HU (1) HU177333B (de)
IT (1) IT1116654B (de)
MX (1) MX4685E (de)
NL (1) NL187167C (de)
NO (2) NO145244C (de)
SE (1) SE426833B (de)
YU (1) YU39804B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6322598A (ja) * 1986-07-14 1988-01-30 Mitsubishi Chem Ind Ltd ゴナトリエン誘導体およびその製造法
HU201091B (en) 1985-12-26 1990-09-28 Mitsubishi Chem Ind Process for producing gonatriene derivatives and pharmaceutical compositions comprising same
JPS6372627A (ja) * 1986-09-17 1988-04-02 Mitsubishi Kasei Corp 子宮内膜症治療薬
JPH0780335B2 (ja) * 1989-11-20 1995-08-30 富士通株式会社 リボンカセット
DK0654267T3 (da) * 1993-11-19 2002-05-13 Jenapharm Gmbh Carcinostatisk middel til hormonterapi indeholdende dienogest som aktiv komponent
EP0780397B1 (de) 1995-12-22 1998-06-10 Jenapharm GmbH & Co. KG Neue 17alpha-Cyanomethylestra-4,9-dien-derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen
US5888543A (en) * 1996-07-26 1999-03-30 American Home Products Corporation Oral contraceptives
US5858405A (en) * 1996-07-26 1999-01-12 American Home Products Corporation Oral contraceptive
US6451778B1 (en) 1996-07-26 2002-09-17 Wyeth Oral contraceptive
US6479475B1 (en) 1996-07-26 2002-11-12 Wyeth Oral contraceptive
HUP0501132A2 (en) * 2005-12-05 2007-06-28 Richter Gedeon Nyrt 17-alpha-cyanomethyl-17betha-hydroxyestra-4,9-diene-3-one of high purity and process for its production
US8617597B2 (en) 2006-07-06 2013-12-31 Bayer Intellectual Property Gmbh Pharmaceutical composition containing a tetrahydrofolic acid
ATE536362T1 (de) * 2009-05-22 2011-12-15 Heyl Chem Pharm Verfahren zur synthese von dienogest aus estron-3-methylether
EP2560984B1 (de) 2010-04-20 2015-04-01 Lupin Limited Verfahren zur herstellung von weitgehend kontaminationsfreiem dienogest
CN112724191B (zh) * 2020-12-30 2022-11-15 上海汇伦医药股份有限公司 一种地诺孕素的精制方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3502699A (en) * 1962-05-15 1970-03-24 Herchel Smith Novel delta4,9-3-ketosteroids and method for preparing same
DE1214223B (de) * 1962-11-22 1966-04-14 Roussel Uclaf Verfahren zur Herstellung von Hydroxy-hydroxymethyl-steroiden
US3624110A (en) * 1964-08-03 1971-11-30 Herchel Smith 13-ethylgona-4,9-dienes
GB1130881A (en) * 1964-08-06 1968-10-16 Merck & Co Inc Steroidal-í¸-dien-3-ones and derivatives thereof
FR2031807A5 (en) * 1969-02-07 1970-11-20 Jenapharm Veb 17a-subst estratrienes
US3931154A (en) * 1973-07-07 1976-01-06 Schering Aktiengesellschaft Process for the preparation of steroid oxiranes
US4029648A (en) * 1976-01-15 1977-06-14 Veb Jenapharm Process of making gona-1,3,5(10),9(11)-tetraenes

Also Published As

Publication number Publication date
SE426833B (sv) 1983-02-14
FR2393008A1 (fr) 1978-12-29
GB1524917A (en) 1978-09-13
JPS616838B2 (de) 1986-03-01
SE7706835L (sv) 1978-01-15
BR7703832A (pt) 1978-04-25
FR2393008B1 (de) 1982-05-07
NO146574B (no) 1982-07-19
FI57113B (fi) 1980-02-29
DE2718872C2 (de) 1987-12-10
FI771865A (de) 1977-12-15
HU177333B (en) 1981-09-28
ES461987A3 (es) 1978-06-01
JPS5312849A (en) 1978-02-04
DK259477A (da) 1977-12-15
US4248790A (en) 1981-02-03
MX4685E (es) 1982-07-30
CH635594A5 (de) 1983-04-15
NL187167C (nl) 1991-06-17
NO772054L (no) 1977-12-15
IT1116654B (it) 1986-02-10
YU39804B (en) 1985-04-30
NL7706465A (nl) 1977-12-16
DE2718872A1 (de) 1977-12-22
NO145244B (no) 1981-11-02
NL187167B (nl) 1991-01-16
NO145244C (no) 1982-02-10
NO146574C (no) 1982-10-27
FI57113C (fi) 1980-06-10
NO811764L (no) 1977-12-15
YU146577A (en) 1982-06-30

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Legal Events

Date Code Title Description
RE20 Patent expired

Owner name: VEB JENAPHARM

Effective date: 19970613