ATE536362T1 - Verfahren zur synthese von dienogest aus estron-3-methylether - Google Patents

Verfahren zur synthese von dienogest aus estron-3-methylether

Info

Publication number
ATE536362T1
ATE536362T1 AT09075237T AT09075237T ATE536362T1 AT E536362 T1 ATE536362 T1 AT E536362T1 AT 09075237 T AT09075237 T AT 09075237T AT 09075237 T AT09075237 T AT 09075237T AT E536362 T1 ATE536362 T1 AT E536362T1
Authority
AT
Austria
Prior art keywords
product
dienogest
estra
methoxy
treating
Prior art date
Application number
AT09075237T
Other languages
English (en)
Inventor
Thomas Doehler
Michael Werner
Dirk-Detlef Walther
Original Assignee
Heyl Chem Pharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41279176&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE536362(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Heyl Chem Pharm filed Critical Heyl Chem Pharm
Application granted granted Critical
Publication of ATE536362T1 publication Critical patent/ATE536362T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0059—Estrane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0081—Substituted in position 17 alfa and 17 beta

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Steroid Compounds (AREA)
AT09075237T 2009-05-22 2009-05-22 Verfahren zur synthese von dienogest aus estron-3-methylether ATE536362T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP09075237A EP2256128B1 (de) 2009-05-22 2009-05-22 Verfahren zur Synthese von Dienogest aus Estron-3-Methylether

Publications (1)

Publication Number Publication Date
ATE536362T1 true ATE536362T1 (de) 2011-12-15

Family

ID=41279176

Family Applications (1)

Application Number Title Priority Date Filing Date
AT09075237T ATE536362T1 (de) 2009-05-22 2009-05-22 Verfahren zur synthese von dienogest aus estron-3-methylether

Country Status (5)

Country Link
US (1) US20100298585A1 (de)
EP (1) EP2256128B1 (de)
AT (1) ATE536362T1 (de)
DE (1) DE102009041893A1 (de)
ES (1) ES2378604T3 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103808855B (zh) * 2014-01-24 2015-11-18 山东师范大学 一种从南极磷虾中提取雌酮的方法及高效薄层层析扫描检测方法
CN108558981B (zh) * 2018-05-08 2020-05-08 浙江仙琚制药股份有限公司 制备双缩酮的方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2729654A (en) * 1954-05-19 1956-01-03 Searle & Co 10-hydroxy-3-ketosteroids
US2940990A (en) * 1956-05-22 1960-06-14 Syntex Sa 17-diacetals of estrone
DE1252679B (de) * 1963-03-14 1967-10-26 Syntex Corporation, Panama (Panama) Verfahren zur Herstellung von zlM.5(10)-A-Homo-östratrien-3-on-derivaten
DD132497A1 (de) 1976-06-14 1978-10-04 Kurt Ponsold Verfahren zur herstellung von neuen gona-4,9(10)-dienen
DE2718872A1 (de) * 1976-06-14 1977-12-22 Jenapharm Veb Verfahren zur herstellung von neuen gona-4,9(10)-dienen
US4167517A (en) * 1976-06-14 1979-09-11 Veb Jenapharm Gona-4,9(10)-dienes and process of producing the same
DD275247A1 (de) 1988-09-01 1990-01-17 Adw Ddr Verfahren zur herstellung von steroiden mit einem 4,9,8(14)-triensystem
EP0411736B1 (de) * 1989-08-04 1994-05-04 Schering Aktiengesellschaft 11 Beta-substituierte 16 alpha, 17alpha-Methylen-estra-4,9-dien-3-one
HUP0501132A2 (en) 2005-12-05 2007-06-28 Richter Gedeon Nyrt 17-alpha-cyanomethyl-17betha-hydroxyestra-4,9-diene-3-one of high purity and process for its production
ITMI20062504A1 (it) 2006-12-22 2008-06-23 Antibioticos Spa Procedimento per la preparazione di 17alfa-cianometil-17beta-idrossi steroidi

Also Published As

Publication number Publication date
EP2256128A1 (de) 2010-12-01
EP2256128B1 (de) 2011-12-07
DE102009041893A1 (de) 2010-12-02
ES2378604T3 (es) 2012-04-16
US20100298585A1 (en) 2010-11-25

Similar Documents

Publication Publication Date Title
Rafiee et al. Cs2. 5H0. 5PW12O40 catalyzed diastereoselective synthesis of β-amino ketones via three component Mannich-type reaction in water
Karmakar et al. K2PdCl4 catalyzed efficient multicomponent synthesis of α-aminonitriles in aqueous media
WO2007089527A3 (en) Method of forming a dianhydrosugar alcohol
MY191517A (en) A clean method for preparing d, l-methionine
Kotani et al. Trichlorosilyl triflate for enantioselective direct-type aldol reaction with chiral phosphine oxide
Kyasa et al. Synthesis of alkyl hydroperoxides via alkylation of gem-dihydroperoxides
EA201892204A2 (ru) Способ получения промежуточных соединений для получения азоксистробина
US20200172453A1 (en) Process for the cyclopropanation of olefins using n-methyl-n-nitroso compounds
Shah et al. Catalyst-free, facile, and an efficient synthesis of α-aminonitriles employing Zn (CN) 2 as an ecofriendly cyanating agent
MY150056A (en) Method for producing hydrogenolysis product of polyhydric alcohol
WO2008099882A1 (ja) ２－メチル－３－（３，４－メチレンジオキシフェニル）プロパナール及びその製造方法
ATE536362T1 (de) Verfahren zur synthese von dienogest aus estron-3-methylether
De Rosa et al. Water opportunities: catalyst and solvent in Mukaiyama aldol addition of Rawal’s diene to carbonyl derivatives
CN102442898A (zh) 一种己二酸的合成方法
Rahimizadeh et al. Preyssler-type heteropoly acid: a new, mild and efficient catalyst for protection of carbonyl compounds
JP2016539104A5 (de)
EA201890300A1 (ru) Способ получения карбонильного соединения ацеталя
Nagarapu et al. HClO4–SiO2 as a novel and recyclable catalyst for the one-pot synthesis of homoallylic amines
Du et al. FTIR study on deactivation of sulfonyl chloride functionalized ionic materials as dual catalysts and media for Beckmann rearrangement of cyclohexanone oxime
Ma et al. Efficient hydrogenation of imines over Fe and ZnO powder in a self-neutralizing acidic CO 2–H 2 O system
Yadav et al. Iron (III) chloride as mild and efficient reagent for the α-thiocyanation of ketones: An expedient synthesis of α-oxo thiocyanates
SG178864A1 (en) Method for producing a compound with a double bond
Shendage et al. Ultrasound assisted synthesis of enaminones using Nickel oxide
ATE543853T1 (de) Verfahren zur herstellung von polyglycerol aus rohglycerol
Nongbe et al. Graphene-catalyzed transacetalization under acid-free conditions