BE836355A - Agents de constraste radiographique non ioniques facilement solubles dans l'eau et procede pour les preparer - Google Patents

Agents de constraste radiographique non ioniques facilement solubles dans l'eau et procede pour les preparer

Info

Publication number
BE836355A
BE836355A BE162511A BE162511A BE836355A BE 836355 A BE836355 A BE 836355A BE 162511 A BE162511 A BE 162511A BE 162511 A BE162511 A BE 162511A BE 836355 A BE836355 A BE 836355A
Authority
BE
Belgium
Prior art keywords
radiographic
preparing
ionic
soluble non
easily water
Prior art date
Application number
BE162511A
Other languages
English (en)
French (fr)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BE836355A publication Critical patent/BE836355A/xx

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/04X-ray contrast preparations
    • A61K49/0433X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/041,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/061,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BE162511A 1974-12-13 1975-12-05 Agents de constraste radiographique non ioniques facilement solubles dans l'eau et procede pour les preparer BE836355A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1658874A CH608189A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1974-12-13 1974-12-13

Publications (1)

Publication Number Publication Date
BE836355A true BE836355A (fr) 1976-06-08

Family

ID=4418593

Family Applications (1)

Application Number Title Priority Date Filing Date
BE162511A BE836355A (fr) 1974-12-13 1975-12-05 Agents de constraste radiographique non ioniques facilement solubles dans l'eau et procede pour les preparer

Country Status (29)

Country Link
US (1) US4001323A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS5182236A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AR (1) AR211853A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (2) AT340582B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU475785B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE (1) BE836355A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BG (1) BG26512A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1046082A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH608189A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CS (1) CS194234B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DD (1) DD122475A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK147336C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES442651A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2293919A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB1472050A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU170216B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE42620B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL48484A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IN (1) IN142089B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MX (1) MX3174E (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL157295B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO145096C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PH (1) PH12321A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PL (1) PL96082B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
RO (1) RO69615A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (1) SE409993B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SU (1) SU628813A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
YU (2) YU40448B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA757222B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Cited By (6)

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FR2354316A1 (fr) * 1976-06-11 1978-01-06 Nyegaard & Co As Nouveaux agents de contraste iodes non-ioniques
EP0082804B1 (de) * 1981-12-18 1987-08-12 Schering Aktiengesellschaft 2-Amino-1-(1,3-dioxolan-4-yl)-ethanol-Verbindungen, deren Herstellung und Verwendung zur Weiterverarbeitung
LT3582B (en) 1989-09-04 1995-12-27 Nycomed Imaging As Contrast media, methods for preparing and using the same
US6660248B2 (en) 2000-11-10 2003-12-09 William Marsh Rice University Fullerene (C60)-based X-ray contrast agent for diagnostic imaging
US7780875B2 (en) 2005-01-13 2010-08-24 Cinvention Ag Composite materials containing carbon nanoparticles
RU2530159C1 (ru) * 2013-04-16 2014-10-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "САНКТ-ПЕТЕРБУРГСКАЯ ГОСУДАРСТВЕННАЯ АКАДЕМИЯ ВЕТЕРИНАРНОЙ МЕДИЦИНЫ" (ФГБОУ ВПО СПБГАВМ) Способ изготовления рентгеноконтрастной массы для вазорентгенографии при посмертных исследованиях животных

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US4314055A (en) * 1975-09-29 1982-02-02 Mallinckrodt, Inc. 3,5-Disubstituted-2,4,6-triiodoanilides of polyhydroxy-monobasic acids
JPS52130923A (en) * 1976-04-27 1977-11-02 Mallinckrodt Chemical Works Xxray photographic agent
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DE2909439A1 (de) * 1979-03-08 1980-09-18 Schering Ag Neue nichtionische roentgenkontrastmittel
US4256729A (en) * 1979-03-23 1981-03-17 Mallinckrodt, Inc. N,N'-Bis-(2,3-dihydroxypropyl)-2,4,6-triiodo-5-(2-keto-L-gulonamido)isophthalamide and radiological compositions containing same
NL8002388A (nl) * 1979-05-21 1980-11-25 Mallinckrodt Inc Roentgencontrastmiddel.
IT1207226B (it) * 1979-08-09 1989-05-17 Bracco Ind Chimica Spa Derivati dell'acido 2,4,6-triiodo-isoftalico, metodo per la loro preparazione e mezzi di contrasto che li contengono.
DE3001292A1 (de) * 1980-01-11 1981-07-16 Schering Ag Berlin Und Bergkamen, 1000 Berlin Nichtionische 5-c-substituierte 2,4,6-trijod-isophthalsaeure-derivate
DE3038853A1 (de) 1980-10-10 1982-05-27 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue n-hydroxy-alkylierte dicarbonsaeure-bis-(3,5-dicarbamoyl-2,4,6-trijodanilide), deren herstellung und diese enthaltende roentgenkonstrastmittel (ii)
DE3150916A1 (de) * 1981-12-18 1983-06-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen N-hydroxyaethylierte 2,4,6-trijodaminoisiophthalsaeure-bis- trihydroxybutylamide, deren herstellung und diese enthaltende roentgenkontrastmittel"
US4396598A (en) * 1982-01-11 1983-08-02 Mallinckrodt, Inc. Triiodoisophthalamide X-ray contrast agent
US5204086A (en) * 1982-10-01 1993-04-20 Nycomed Imaging As X-ray contrast agent
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US5035877A (en) * 1985-08-09 1991-07-30 Cook Imaging Corporation Non-ionic contrast media from ionic contrast media
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IL94718A (en) * 1989-07-05 1994-10-21 Schering Ag Non-ionic carboxamide contrast agent and method of preparation
US5698739A (en) * 1989-07-05 1997-12-16 Schering Aktiengesellschaft Carboxamide non-ionic contrast media
DE3937118A1 (de) * 1989-11-03 1991-05-08 Schering Ag Nichtionische roentgenkontrastmittel mit hohem jodgehalt
US5232685A (en) * 1989-11-03 1993-08-03 Schering Aktiengesellschaft Nonionic x-ray contrast medium with high iodine content
US5614638A (en) * 1989-11-29 1997-03-25 Bracco International B.V. Nonionic radiographic contrast agents
US5075502A (en) * 1989-12-13 1991-12-24 Mallinckrodt, Inc. Nonionic x-ray contrast agents, compositions and methods
US4997983A (en) * 1990-01-31 1991-03-05 Mallinckrodt, Inc. Process for production of ioversol
IT1248741B (it) * 1991-02-26 1995-01-26 Bracco Spa Processo di concentrazione e di purificazione di composti organici
US5169864A (en) * 1991-11-15 1992-12-08 Baxter International Inc. Unbuffered premixed ranitidine formulation
US5463080A (en) * 1992-08-27 1995-10-31 Bracco International B.V. 2,4,6-triiodo-1,3-benzenedicarboxylic acid compounds used as radiolabelling reagents
IT1256163B (it) * 1992-10-27 1995-11-29 Zambon Spa Processo per la preparazione di un intermedio della sintesi organica
IT1256162B (it) * 1992-10-27 1995-11-29 Zambon Spa Processo per la preparazione di un intermedio della sintesi organica
IT1256248B (it) * 1992-12-24 1995-11-29 Bracco Spa Formulazioni iniettabili acquose per radiodiagnostica comprendenti miscele di composti aromatici iodurati utili come agenti opacizzanti ai raggi x
US5424056A (en) * 1993-03-01 1995-06-13 Sterling Wintrhop Inc. X-ray contrast compositions containing iodoaniline derivatives and pharmaceutically acceptable clays
US5330740A (en) * 1993-03-01 1994-07-19 Sterling Winthrop Inc. Compositions of iodoaniline derivatives in film-forming materials for visualization of the gastrointestinal tract
IL110391A (en) * 1993-07-30 1998-12-06 Zambon Spa Process for the crystallization of iopamidol
IT1271469B (it) * 1993-09-10 1997-05-28 Zambon Spa Processo per la preparazione di 5-ammino-2,2-dialchil-1,3 diossani
IT1274027B (it) * 1994-03-03 1997-07-14 Zambon Spa Processo per la preparazione e purificazione di mezzi di contrasto iodurati
IT1275429B (it) * 1995-05-18 1997-08-07 Zambon Spa Processo per la preparazione di un intermedio utile nella sintesi di composti organici
DE69601525T2 (de) * 1995-05-23 1999-06-24 Fructamine S.P.A., Mozzo Verfahren zur herstellung von dicarbonsäurechlorid
SI9620010B (sl) * 1995-05-23 1998-08-31 Fructamine S.P.A. Postopek za pripravo diklorida dikarboksilne kisline
PT101720A (pt) * 1995-06-08 1997-01-31 Hovione Sociedade Quimica S A Processo para a purificacao e cristalizacao de iopamidol
CN1070843C (zh) * 1995-09-08 2001-09-12 伯拉考国际股份公司 (s)-n,n'-二[2-羟基-1-(羟甲基)乙基)-5-[(2-羟基-1-氧代丙基)氨基]-2,4,6-三碘-1,3-苯二羧酰胺从水中结晶的方法
DE69623597T2 (de) * 1995-12-19 2003-05-22 Bracco Research S.A., Carouge Tricodobenzene-polymere enthaltende zusammensetzungen zur abbildung des gastrointestinaltraktes
IT1283319B1 (it) * 1996-03-29 1998-04-16 Zambon Spa Processo per la preparazione di un intermedio utile nella sintesi di mezzi di contrasto iodurati
IT1288114B1 (it) * 1996-06-13 1998-09-10 Fructamine Spa Processo per la purificazione di un intermedio
GB9618056D0 (en) * 1996-08-29 1996-10-09 Nycomed Imaging As Process
US5705692A (en) * 1996-09-27 1998-01-06 Abbott Laboratories Process for the preparation of iohexol
US5861138A (en) * 1996-11-20 1999-01-19 Hoechst Celanese Corp. Ligands for MRI contrast agent
US5861140A (en) * 1996-11-20 1999-01-19 Hoechst Celanese Corp. Tripodal paramagnetic contrast agents for MR imaging
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IT1286522B1 (it) * 1996-12-04 1998-07-15 Dibra Spa Processo per la preparazione di derivati dell'acido 5-ammino-2,4,6- triiodo-1,3-benzenedicarbossilico
IT1289520B1 (it) * 1996-12-24 1998-10-15 Zambon Spa Processo per la preparazione di un intermedio utile nella sintesi di mezzi di contrasto iodurati
IT1289519B1 (it) * 1996-12-24 1998-10-15 Zambon Spa Processo per la preparazione di un intermedio utile nella sintesi di mezzi di contrasto iodurati
IT1289521B1 (it) * 1996-12-24 1998-10-15 Zambon Spa Processo per la purificazione di un intermedio
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IT1319671B1 (it) * 2000-12-01 2003-10-23 Bracco Spa Processo per la preparazione di (s)-n,n'-bis(2-idrossi-1-(idrossimetil)etil)-5-((2-idrossi-1-ossopropil)ammino)
SE522098C2 (sv) * 2001-12-20 2004-01-13 Bone Support Ab Ett nytt benmineralsubstitut
SE0300620D0 (sv) * 2003-03-05 2003-03-05 Bone Support Ab A new bone substitute composition
SE0302983D0 (sv) * 2003-11-11 2003-11-11 Bone Support Ab Anordning för att förse spongiöst ben med benersättnings- och/eller benförstärkningsmaterial och förfarande i samband därmed
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CN104230731B (zh) * 2014-09-24 2016-01-20 武汉理工大学 造影剂中间体三碘异酞酰氯的制备方法
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CN105461581A (zh) * 2015-11-17 2016-04-06 浙江海洲制药有限公司 碘帕醇杂质a和杂质b的合成方法
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JP7012722B2 (ja) * 2016-12-05 2022-01-28 ブラッコ・イメージング・ソシエタ・ペル・アチオニ 放射線画像診断剤中間体の機械化学的合成
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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2354316A1 (fr) * 1976-06-11 1978-01-06 Nyegaard & Co As Nouveaux agents de contraste iodes non-ioniques
JPS5321137A (en) * 1976-06-11 1978-02-27 Serukapeto Xxray contrast medium
EP0082804B1 (de) * 1981-12-18 1987-08-12 Schering Aktiengesellschaft 2-Amino-1-(1,3-dioxolan-4-yl)-ethanol-Verbindungen, deren Herstellung und Verwendung zur Weiterverarbeitung
LT3582B (en) 1989-09-04 1995-12-27 Nycomed Imaging As Contrast media, methods for preparing and using the same
US6660248B2 (en) 2000-11-10 2003-12-09 William Marsh Rice University Fullerene (C60)-based X-ray contrast agent for diagnostic imaging
US7780875B2 (en) 2005-01-13 2010-08-24 Cinvention Ag Composite materials containing carbon nanoparticles
RU2530159C1 (ru) * 2013-04-16 2014-10-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "САНКТ-ПЕТЕРБУРГСКАЯ ГОСУДАРСТВЕННАЯ АКАДЕМИЯ ВЕТЕРИНАРНОЙ МЕДИЦИНЫ" (ФГБОУ ВПО СПБГАВМ) Способ изготовления рентгеноконтрастной массы для вазорентгенографии при посмертных исследованиях животных

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DK567475A (da) 1976-06-14
CS194234B2 (en) 1979-11-30
HU170216B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1977-04-28
RO69615A (ro) 1981-06-30
AU8751675A (en) 1976-09-02
AR211853A1 (es) 1978-03-31
ATA925075A (de) 1977-04-15
SE409993B (sv) 1979-09-17
YU40448B (en) 1986-02-28
IE42620L (en) 1976-06-13
BG26512A3 (bg) 1979-04-12
IL48484A0 (en) 1976-01-30
DK147336B (da) 1984-06-25
SE7514076L (sv) 1976-06-14
YU315575A (en) 1982-02-28
DD122475A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1976-10-12
DE2547789A1 (de) 1976-06-24
SU628813A3 (ru) 1978-10-15
US4001323A (en) 1977-01-04
IE42620B1 (en) 1980-09-10
GB1472050A (en) 1977-04-27
PL96082B1 (pl) 1977-12-31
DE2547789B2 (de) 1977-02-24
IN142089B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1977-05-28
NO754241L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1976-06-15
ES442651A1 (es) 1977-04-16
MX3174E (es) 1980-06-09
PH12321A (en) 1979-01-16
JPS5642581B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1981-10-06
AT342579B (de) 1978-04-10
CH608189A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1978-12-29
FR2293919B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1980-06-20
DK147336C (da) 1985-01-21
NO145096C (no) 1982-01-13
NO145096B (no) 1981-10-05
ZA757222B (en) 1976-11-24
AT340582B (de) 1977-12-27
NL157295B (nl) 1978-07-17
IL48484A (en) 1978-08-31
YU196783A (en) 1984-12-31
AU475785B2 (en) 1976-09-02
ATA925175A (de) 1977-08-15
NL7512208A (nl) 1976-06-15
FR2293919A1 (fr) 1976-07-09
JPS5182236A (en) 1976-07-19
YU41540B (en) 1987-08-31
CA1046082A (en) 1979-01-09

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