|
GB0018891D0
(en)
*
|
2000-08-01 |
2000-09-20 |
Novartis Ag |
Organic compounds
|
|
WO2003057214A1
(en)
|
2001-12-28 |
2003-07-17 |
Somatocor Pharmaceuticals, Inc. |
Imidazolidin-2,4-dione derivatives as non-peptide somatostatin receptor ligands
|
|
GB0229020D0
(en)
*
|
2002-12-12 |
2003-01-15 |
Novartis Ag |
Organic compounds
|
|
AU2003290019B2
(en)
|
2002-12-12 |
2007-09-27 |
Recordati Ag |
Process for peptide synthesis of peptides containing a 4-hydroxy-proline substructure
|
|
GB0300095D0
(en)
*
|
2003-01-03 |
2003-02-05 |
Novartis Ag |
Organic compounds
|
|
AR044852A1
(es)
*
|
2003-06-24 |
2005-10-05 |
Novartis Ag |
Una composicion farmaceutica para la administracion parenteral que comprende un analogo de somatostatina
|
|
GB0314695D0
(en)
*
|
2003-06-24 |
2003-07-30 |
Novartis Ag |
Organic compounds
|
|
GB0318682D0
(en)
*
|
2003-08-08 |
2003-09-10 |
Novartis Ag |
Organic compounds
|
|
EP1522311A1
(fr)
|
2003-10-10 |
2005-04-13 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Utilisation de la somatostine ou d'un de ses analogues pour préparer un médicament destiné à réguler la réserve folliculaire ovarienne chez la femme non ménopausée
|
|
MY158342A
(en)
*
|
2003-11-14 |
2016-09-30 |
Novartis Ag |
Pharmaceutical composition
|
|
GB0412866D0
(en)
*
|
2004-06-09 |
2004-07-14 |
Novartis Ag |
Organic compounds
|
|
GB0428151D0
(en)
|
2004-12-22 |
2005-01-26 |
Novartis Ag |
Organic compounds
|
|
GB0602639D0
(en)
|
2006-02-09 |
2006-03-22 |
Novartis Ag |
Organic compounds
|
|
WO2007141306A2
(en)
*
|
2006-06-08 |
2007-12-13 |
Novartis Ag |
Combination of somatostatin-analogs with dopamine- or growth hormone receptor antagonist
|
|
US7697338B2
(en)
*
|
2006-11-16 |
2010-04-13 |
Sandisk Corporation |
Systems for controlled boosting in non-volatile memory soft programming
|
|
WO2008064570A1
(en)
*
|
2006-11-28 |
2008-06-05 |
The University Of Hong Kong |
The use of granulin-epithelin precursor (gep) antibodies for detection and suppression of hepatocellular carcinoma (hcc)
|
|
EP1941902A1
(en)
*
|
2007-01-02 |
2008-07-09 |
Novartis AG |
Use of Somatostatin analogs in cluster headache
|
|
US8889632B2
(en)
|
2007-01-31 |
2014-11-18 |
Dana-Farber Cancer Institute, Inc. |
Stabilized p53 peptides and uses thereof
|
|
JP5631201B2
(ja)
|
2007-03-28 |
2014-11-26 |
プレジデント アンド フェローズ オブ ハーバード カレッジ |
ステッチングされたポリペプチド
|
|
PE20090387A1
(es)
|
2007-05-24 |
2009-04-28 |
Novartis Ag |
Formulacion de pasireotida
|
|
WO2009009035A1
(en)
*
|
2007-07-06 |
2009-01-15 |
Ipsen Pharma S.A.S. |
Somatostatin analog and uses thereof
|
|
GB0719818D0
(en)
*
|
2007-10-11 |
2007-11-21 |
Asterion Ltd |
Growth hormone fusion polypeptides
|
|
ES2536778T3
(es)
*
|
2007-11-28 |
2015-05-28 |
Novartis Ag |
Uso de análogos de somatostatina en meningioma
|
|
PL2225271T3
(pl)
|
2007-12-03 |
2013-12-31 |
Italfarmaco Spa |
Nowe nieselektywne analogi somatostatyny
|
|
EP2067786A1
(en)
|
2007-12-07 |
2009-06-10 |
ITALFARMACO S.p.A. |
Novel non selective analogs of somatostatin
|
|
US20090325863A1
(en)
*
|
2008-06-13 |
2009-12-31 |
Kleinberg David L |
Somatostatin analogs and IGF-I inhibition for breast cancer prevention
|
|
HRP20130145T1
(hr)
|
2008-07-08 |
2013-03-31 |
Novartis Ag |
Uporaba pasireotida za lijeäśenje endogene hiperinzulinemijske hipoglikemije
|
|
EP2172189A1
(en)
|
2008-10-01 |
2010-04-07 |
Novartis AG |
Pharmaceutical Compositions
|
|
EP2213307A1
(en)
|
2009-02-03 |
2010-08-04 |
Novartis AG |
Injectable depot formulations
|
|
WO2010032140A2
(en)
|
2008-09-17 |
2010-03-25 |
Chiasma Inc. |
Pharmaceutical compositions and related methods of delivery
|
|
UY33236A
(es)
|
2010-02-25 |
2011-09-30 |
Novartis Ag |
Inhibidores dimericos de las iap
|
|
KR20180058866A
(ko)
|
2010-08-13 |
2018-06-01 |
에일러론 테라퓨틱스 인코포레이티드 |
펩티도미메틱 거대고리
|
|
WO2012074559A2
(en)
|
2010-12-02 |
2012-06-07 |
New York University |
Treatment of non-proliferative cystic disease
|
|
UY33794A
(es)
|
2010-12-13 |
2012-07-31 |
Novartis Ag |
Inhibidores diméricos de las iap
|
|
JP2014501235A
(ja)
|
2010-12-13 |
2014-01-20 |
ノバルティス アーゲー |
二量体iap阻害剤
|
|
US20130035054A1
(en)
*
|
2011-07-14 |
2013-02-07 |
Faceon Mobile |
Phone with multi-portal access for display during incoming and outgoing call
|
|
WO2013019923A2
(en)
|
2011-08-02 |
2013-02-07 |
New York University |
Methods for detecting progenitor cells and uses thereof
|
|
PH12014500682A1
(en)
|
2011-09-27 |
2014-05-12 |
Novartis Ag |
3-pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant idh
|
|
BR112014009418A2
(pt)
|
2011-10-18 |
2017-04-18 |
Aileron Therapeutics Inc |
macrociclos peptidomiméticos
|
|
MX2014006736A
(es)
|
2011-12-05 |
2014-08-29 |
Novartis Ag |
Derivados de urea ciclicos como antagonistas de los receptores de androgeno.
|
|
BR112014013693B1
(pt)
|
2011-12-05 |
2023-01-31 |
Camurus Ab |
Pré-formulação, e, uso de uma pré-formulação
|
|
JP6158833B2
(ja)
|
2012-01-09 |
2017-07-05 |
アローヘッド ファーマシューティカルズ インコーポレイテッド |
ベータ−カテニン関連疾患を処置するための有機組成物
|
|
US8815926B2
(en)
|
2012-01-26 |
2014-08-26 |
Novartis Ag |
Substituted pyrrolo[3,4-D]imidazoles for the treatment of MDM2/4 mediated diseases
|
|
WO2013123267A1
(en)
|
2012-02-15 |
2013-08-22 |
Aileron Therapeutics, Inc. |
Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles
|
|
CN112500466B
(zh)
|
2012-02-15 |
2022-05-03 |
艾瑞朗医疗公司 |
拟肽大环化合物
|
|
EA035495B1
(ru)
*
|
2012-05-25 |
2020-06-25 |
Камурус Аб |
Состав-предшественник, содержащий агонист рецепторов соматостатина, способ лечения путем его введения, его применение, предварительно заполненное устройство, содержащее его, и набор, содержащий указанное устройство
|
|
TWI704919B
(zh)
|
2012-05-31 |
2020-09-21 |
日商大塚製藥股份有限公司 |
用於預防及/或治療多囊性腎臟病之藥物
|
|
MX2015005244A
(es)
|
2012-11-01 |
2015-07-14 |
Aileron Therapeutics Inc |
Aminoacidos disustituidos y metodos de preparacion y el uso de los mismos.
|
|
EP2922578B1
(en)
|
2012-11-21 |
2018-12-12 |
Serene, Llc |
Tin-117m comprising somatostatin receptor binding compounds
|
|
JP6364028B2
(ja)
|
2013-02-19 |
2018-07-25 |
ノバルティス アーゲー |
選択的エストロゲン受容体ディグレーダーとしてのベンゾチオフェン誘導体およびその組成物
|
|
WO2014141104A1
(en)
|
2013-03-14 |
2014-09-18 |
Novartis Ag |
3-pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant idh
|
|
MX2015012822A
(es)
|
2013-03-14 |
2016-05-31 |
Novartis Ag |
3-pirimidin-4-il-oxazolidin-2-onas- como inhibidores del idh mutante.
|
|
WO2014147586A1
(en)
|
2013-03-22 |
2014-09-25 |
Novartis Ag |
1-(2-(ethylamino)pyrimidin-4-yl)pyrrolidin-2-ones as inhibitors of mutant idh
|
|
CN103467575B
(zh)
*
|
2013-08-22 |
2016-03-02 |
深圳翰宇药业股份有限公司 |
一种帕西瑞肽的制备方法
|
|
CN103641894B
(zh)
*
|
2013-12-06 |
2015-10-28 |
深圳翰宇药业股份有限公司 |
一种治疗库欣病的多肽药物的制备方法
|
|
WO2015092634A1
(en)
|
2013-12-16 |
2015-06-25 |
Novartis Ag |
1,2,3,4-tetrahydroisoquinoline compounds and compositions as selective estrogen receptor antagonists and degraders
|
|
CN105828803B
(zh)
|
2013-12-19 |
2019-06-07 |
诺华股份有限公司 |
药物递送系统
|
|
JO3517B1
(ar)
|
2014-01-17 |
2020-07-05 |
Novartis Ag |
ان-ازاسبيرو الكان حلقي كبديل مركبات اريل-ان مغايرة وتركيبات لتثبيط نشاط shp2
|
|
EP3094627B1
(en)
|
2014-01-17 |
2018-08-22 |
Novartis AG |
1-pyridazin-/triazin-3-yl-piper(-azine)/idine/pyrolidine derivatives and and compositions thereof for inhibiting the activity of shp2
|
|
ES2699354T3
(es)
|
2014-01-17 |
2019-02-08 |
Novartis Ag |
Derivados de 1-(triazin-3-il/piridazin-3-il)-piper(-azin)idina y composiciones de las mismas para inhibir la actividad de SHP2
|
|
JOP20200094A1
(ar)
|
2014-01-24 |
2017-06-16 |
Dana Farber Cancer Inst Inc |
جزيئات جسم مضاد لـ pd-1 واستخداماتها
|
|
JOP20200096A1
(ar)
|
2014-01-31 |
2017-06-16 |
Children’S Medical Center Corp |
جزيئات جسم مضاد لـ tim-3 واستخداماتها
|
|
US20150259420A1
(en)
|
2014-03-14 |
2015-09-17 |
Novartis Ag |
Antibody molecules to lag-3 and uses thereof
|
|
AU2015265607A1
(en)
|
2014-05-28 |
2016-11-17 |
Idenix Pharmaceuticals Llc |
Nucleoside derivatives for the treatment of cancer
|
|
AU2015320549A1
(en)
|
2014-09-24 |
2017-04-13 |
Aileron Therapeutics, Inc. |
Peptidomimetic macrocycles and uses thereof
|
|
MA41044A
(fr)
|
2014-10-08 |
2017-08-15 |
Novartis Ag |
Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer
|
|
ES2952717T3
(es)
|
2014-10-14 |
2023-11-03 |
Novartis Ag |
Moléculas de anticuerpos contra PD-L1 y usos de las mismas
|
|
EP3226688B1
(en)
|
2014-12-05 |
2020-07-01 |
Merck Sharp & Dohme Corp. |
Tricyclic compounds as inhibitors of mutant idh enzymes
|
|
WO2016089833A1
(en)
|
2014-12-05 |
2016-06-09 |
Merck Sharp & Dohme Corp. |
Novel tricyclic compounds as inhibitors of mutant idh enzymes
|
|
EP3226689B1
(en)
|
2014-12-05 |
2020-01-15 |
Merck Sharp & Dohme Corp. |
Novel tricyclic compounds as inhibitors of mutant idh enzymes
|
|
MA41159A
(fr)
|
2014-12-10 |
2021-05-12 |
Chiasma Inc |
Octréotide destiné à être administré par voie orale en association avec d'autres agents thérapeutiques
|
|
WO2016100882A1
(en)
|
2014-12-19 |
2016-06-23 |
Novartis Ag |
Combination therapies
|
|
WO2016097962A1
(en)
|
2014-12-19 |
2016-06-23 |
Auro Peptides Ltd |
A process for the preparation of pasireotide
|
|
HUE071943T2
(hu)
|
2015-02-03 |
2025-10-28 |
Amryt Endo Inc |
Akromegália kezelése oktreotid orális alkalmazásával
|
|
HK1248603A1
(zh)
|
2015-03-10 |
2018-10-19 |
Aduro Biotech, Inc. |
用於活化"干扰素基因的刺激剂"依懒性信号传导的组合物和方法
|
|
SG11201707750YA
(en)
|
2015-03-20 |
2017-10-30 |
Aileron Therapeutics Inc |
Peptidomimetic macrocycles and uses thereof
|
|
EP3280723B1
(en)
*
|
2015-04-08 |
2021-01-06 |
Polyphor AG |
Backbone-cyclized peptidomimetics
|
|
EP3303361A1
(en)
|
2015-05-27 |
2018-04-11 |
Idenix Pharmaceuticals LLC |
Nucleotides for the treatment of cancer
|
|
WO2016203406A1
(en)
|
2015-06-19 |
2016-12-22 |
Novartis Ag |
Compounds and compositions for inhibiting the activity of shp2
|
|
US10308660B2
(en)
|
2015-06-19 |
2019-06-04 |
Novartis Ag |
Compounds and compositions for inhibiting the activity of SHP2
|
|
ES2741746T3
(es)
|
2015-06-19 |
2020-02-12 |
Novartis Ag |
Compuestos y composiciones para inhibir la actividad de SHP2
|
|
US10556924B2
(en)
|
2015-06-22 |
2020-02-11 |
Biophore India Pharmaceuticals Pvt. Ltd. |
Process for the preparation of pasireotide
|
|
GB201511790D0
(en)
|
2015-07-06 |
2015-08-19 |
Iomet Pharma Ltd |
Pharmaceutical compound
|
|
JP6878405B2
(ja)
|
2015-07-29 |
2021-05-26 |
ノバルティス アーゲー |
Pd−1に対する抗体分子を含む組み合わせ治療
|
|
PT3317301T
(pt)
|
2015-07-29 |
2021-07-09 |
Novartis Ag |
Terapias de associação compreendendo moléculas de anticorpo contra lag-3
|
|
EP3878465A1
(en)
|
2015-07-29 |
2021-09-15 |
Novartis AG |
Combination therapies comprising antibody molecules to tim-3
|
|
US11453697B1
(en)
|
2015-08-13 |
2022-09-27 |
Merck Sharp & Dohme Llc |
Cyclic di-nucleotide compounds as sting agonists
|
|
JP6596146B2
(ja)
|
2015-08-13 |
2019-10-23 |
メルク・シャープ・アンド・ドーム・コーポレーション |
Stingアゴニストとしての環状ジヌクレオチド化合物
|
|
EP4046655A1
(en)
|
2015-11-03 |
2022-08-24 |
Janssen Biotech, Inc. |
Antibodies specifically binding pd-1 and their uses
|
|
WO2017106062A1
(en)
|
2015-12-15 |
2017-06-22 |
Merck Sharp & Dohme Corp. |
Novel compounds as indoleamine 2,3-dioxygenase inhibitors
|
|
JP2019503349A
(ja)
|
2015-12-17 |
2019-02-07 |
ノバルティス アーゲー |
Pd−1に対する抗体分子およびその使用
|
|
WO2017191599A1
(en)
|
2016-05-04 |
2017-11-09 |
Genoscience Pharma |
Substituted 2, 4-diamino-quinoline derivatives for use in the treatment of proliferative diseases
|
|
JP6994474B2
(ja)
|
2016-06-14 |
2022-01-14 |
ノバルティス アーゲー |
Shp2の活性を阻害するための化合物および組成物
|
|
WO2018009466A1
(en)
|
2016-07-05 |
2018-01-11 |
Aduro Biotech, Inc. |
Locked nucleic acid cyclic dinucleotide compounds and uses thereof
|
|
UA125223C2
(uk)
|
2016-10-04 |
2022-02-02 |
Мерк Шарп І Доум Корп. |
СПОЛУКИ БЕНЗО[b]ТІОФЕНУ ЯК АГОНІСТИ STING
|
|
WO2018091542A1
(en)
|
2016-11-21 |
2018-05-24 |
Idenix Pharmaceuticals Llc |
Cyclic phosphate substituted nucleoside derivatives for the treatment of liver diseases
|
|
AU2018212788A1
(en)
|
2017-01-27 |
2019-07-25 |
Janssen Biotech, Inc. |
Cyclic dinucleotides as STING agonists
|
|
JP7213188B2
(ja)
|
2017-01-27 |
2023-01-26 |
ヤンセン バイオテツク,インコーポレーテツド |
Stingアゴニストとしての環状ジヌクレオチド
|
|
UY37695A
(es)
|
2017-04-28 |
2018-11-30 |
Novartis Ag |
Compuesto dinucleótido cíclico bis 2’-5’-rr-(3’f-a)(3’f-a) y usos del mismo
|
|
US11466047B2
(en)
|
2017-05-12 |
2022-10-11 |
Merck Sharp & Dohme Llc |
Cyclic di-nucleotide compounds as sting agonists
|
|
US20200172628A1
(en)
|
2017-06-22 |
2020-06-04 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
|
AU2018311966A1
(en)
|
2017-08-04 |
2020-02-13 |
Merck Sharp & Dohme Llc |
Benzo[b]thiophene sting agonists for cancer treatment
|
|
US11312772B2
(en)
|
2017-08-04 |
2022-04-26 |
Merck Sharp & Dohme Corp. |
Combinations of PD-1 antagonists and benzo [b] thiophene STING agonists for cancer treatment
|
|
TWI851542B
(zh)
|
2017-09-11 |
2024-08-11 |
美商克魯松藥物公司 |
Shp2之八氫環戊烷并[c]吡咯別構抑制劑
|
|
WO2019067332A1
(en)
|
2017-09-27 |
2019-04-04 |
Merck Sharp & Dohme Corp. |
COMPOSITIONS AND METHODS FOR TREATING CANCER THROUGH A COMBINATION OF PROGRAMMED DEATH ANTIBODY ANTIBODIES (PD-1) AND A CXCR2 ANTAGONIST
|
|
WO2019078968A2
(en)
*
|
2017-10-18 |
2019-04-25 |
Angex Pharmaceutical, Inc. |
CYCLIC COMPOUNDS AS IMMUNOMODULATORS
|
|
EP3703692B1
(en)
|
2017-11-01 |
2025-07-23 |
Merck Sharp & Dohme LLC |
Novel substituted tetrahydroquinolin compounds as indoleamine 2,3-dioxygenase (ido) inhibitors
|
|
BR112020008258B8
(pt)
|
2017-11-14 |
2023-01-31 |
Merck Sharp & Dohme |
Compostos de biarila substituída ou seus sais farmaceuticamente aceitáveis, sua composição e seu uso como inibidores de indoleamina 2,3-dioxigenase (ido)
|
|
EP3709986B1
(en)
|
2017-11-14 |
2023-11-01 |
Merck Sharp & Dohme LLC |
Novel substituted biaryl compounds as indoleamine 2,3-dioxygenase (ido) inhibitors
|
|
ES2927194T3
(es)
|
2017-12-15 |
2022-11-03 |
Janssen Biotech Inc |
Dinucleótidos cíclicos como agonistas de STING
|
|
WO2019125974A1
(en)
|
2017-12-20 |
2019-06-27 |
Merck Sharp & Dohme Corp. |
Cyclic di-nucleotide compounds as sting agonists
|
|
US12398209B2
(en)
|
2018-01-22 |
2025-08-26 |
Janssen Biotech, Inc. |
Methods of treating cancers with antagonistic anti-PD-1 antibodies
|
|
WO2019177873A1
(en)
|
2018-03-13 |
2019-09-19 |
Merck Sharp & Dohme Corp. |
Arginase inhibitors and methods of use
|
|
EP3774765A4
(en)
|
2018-04-03 |
2021-12-29 |
Merck Sharp & Dohme Corp. |
Aza-benzothiophene compounds as sting agonists
|
|
JP7326319B2
(ja)
|
2018-04-03 |
2023-08-15 |
メルク・シャープ・アンド・ドーム・エルエルシー |
Stingアゴニストとしてのベンゾチオフェン類及び関連する化合物
|
|
EP3781687A4
(en)
|
2018-04-20 |
2022-02-09 |
Merck Sharp & Dohme Corp. |
NEW RIG-I SUBSTITUTED AGONISTS: COMPOSITIONS AND METHODS THEREOF
|
|
AR126019A1
(es)
|
2018-05-30 |
2023-09-06 |
Novartis Ag |
Anticuerpos frente a entpd2, terapias de combinación y métodos de uso de los anticuerpos y las terapias de combinación
|
|
WO2019231870A1
(en)
|
2018-05-31 |
2019-12-05 |
Merck Sharp & Dohme Corp. |
Novel substituted [1.1.1] bicyclo compounds as indoleamine 2,3-dioxygenase inhibitors
|
|
WO2019245890A1
(en)
|
2018-06-20 |
2019-12-26 |
Merck Sharp & Dohme Corp. |
Arginase inhibitors and methods of use
|
|
US10596278B2
(en)
|
2018-07-25 |
2020-03-24 |
Advanced Accelerator Applications (Italy) S.R.L. |
Stable, concentrated radionuclide complex solutions
|
|
US10596276B2
(en)
|
2018-07-25 |
2020-03-24 |
Advanced Accelerator Applications (Italy) S.R.L. |
Stable, concentrated radionuclide complex solutions
|
|
TWI888355B
(zh)
|
2018-07-25 |
2025-07-01 |
法商高級催化劑應用品有限公司 |
穩定的、濃縮的放射性核種錯合物溶液
|
|
WO2020061103A1
(en)
|
2018-09-18 |
2020-03-26 |
Nikang Therapeutics, Inc. |
Fused tricyclic ring derivatives as src homology-2 phosphatase inhibitors
|
|
CN113382986A
(zh)
|
2018-09-25 |
2021-09-10 |
黑钻治疗公司 |
酪氨酸激酶抑制剂组合物、其制备方法和使用方法
|
|
EP3856349A1
(en)
|
2018-09-25 |
2021-08-04 |
Black Diamond Therapeutics, Inc. |
Tyrosine kinase inhibitor compositions, methods of making and methods of use
|
|
JP2022502385A
(ja)
|
2018-09-29 |
2022-01-11 |
ノバルティス アーゲー |
Shp2の活性を阻害するための化合物の製造方法
|
|
WO2020092183A1
(en)
|
2018-11-01 |
2020-05-07 |
Merck Sharp & Dohme Corp. |
Novel substituted pyrazole compounds as indoleamine 2,3-dioxygenase inhibitors
|
|
EP3877366B1
(en)
|
2018-11-06 |
2026-01-28 |
Merck Sharp & Dohme LLC |
Novel substituted tricyclic compounds as indoleamine 2,3-dioxygenase inhibitors
|
|
WO2020112581A1
(en)
|
2018-11-28 |
2020-06-04 |
Merck Sharp & Dohme Corp. |
Novel substituted piperazine amide compounds as indoleamine 2, 3-dioxygenase (ido) inhibitors
|
|
WO2020131598A1
(en)
|
2018-12-18 |
2020-06-25 |
Merck Sharp & Dohme Corp. |
Arginase inhibitors and methods of use
|
|
WO2020205688A1
(en)
|
2019-04-04 |
2020-10-08 |
Merck Sharp & Dohme Corp. |
Inhibitors of histone deacetylase-3 useful for the treatment of cancer, inflammation, neurodegeneration diseases and diabetes
|
|
WO2020260547A1
(en)
|
2019-06-27 |
2020-12-30 |
Rigontec Gmbh |
Design method for optimized rig-i ligands
|
|
KR20220056176A
(ko)
|
2019-08-02 |
2022-05-04 |
메르사나 테라퓨틱스, 인코포레이티드 |
암 치료를 위한 sting(인터페론 유전자의 자극인자) 작용제로서의 비스-[n-((5-카바모일)-1h-벤조[d]이미다졸-2-일)-피라졸-5-카복사미드] 유도체 및 관련 화합물
|
|
CN114787150A
(zh)
|
2019-08-15 |
2022-07-22 |
黑钻治疗公司 |
炔基喹唑啉化合物
|
|
WO2021053559A1
(en)
|
2019-09-18 |
2021-03-25 |
Novartis Ag |
Entpd2 antibodies, combination therapies, and methods of using the antibodies and combination therapies
|
|
MX2022005187A
(es)
|
2019-10-28 |
2022-07-27 |
Shanghai Inst Materia Medica Cas |
Compuesto de ácido oxocarboxílico heterocíclico de cinco miembros y el uso médico del mismo.
|
|
WO2021113679A1
(en)
|
2019-12-06 |
2021-06-10 |
Mersana Therapeutics, Inc. |
Dimeric compounds as sting agonists
|
|
US20220396577A1
(en)
|
2019-12-17 |
2022-12-15 |
Merck Sharp & Dohme Llc |
Novel substituted 1,3-8-triazaspiro[4,5] decane-2,4-dione compounds as indoleamine 2,3-dioxygenase (ido) and/or tryptophan 2,3-dioxygenase (tdo) inhibitors
|
|
US20230140132A1
(en)
|
2020-01-07 |
2023-05-04 |
Merck Sharp & Dohme Llc |
Arginase inhibitors and methods of use
|
|
WO2021195206A1
(en)
|
2020-03-24 |
2021-09-30 |
Black Diamond Therapeutics, Inc. |
Polymorphic forms and related uses
|
|
CA3174297A1
(en)
|
2020-04-02 |
2021-10-07 |
Jeremy R. Duvall |
Antibody drug conjugates comprising sting agonists
|
|
JP7311720B2
(ja)
|
2020-05-06 |
2023-07-19 |
メルク・シャープ・アンド・ドーム・エルエルシー |
Il4i1阻害剤及び使用方法
|
|
CA3202355A1
(en)
|
2020-12-22 |
2022-06-30 |
Jiping Fu |
Compounds for degrading cyclin-dependent kinase 2 via ubiquitin proteosome pathway
|
|
US11141457B1
(en)
|
2020-12-28 |
2021-10-12 |
Amryt Endo, Inc. |
Oral octreotide therapy and contraceptive methods
|
|
JP2024504932A
(ja)
|
2021-01-13 |
2024-02-02 |
モンテ ローザ セラピューティクス, インコーポレイテッド |
イソインドリノン化合物
|
|
WO2022170052A1
(en)
|
2021-02-05 |
2022-08-11 |
Black Diamond Therapeutics, Inc. |
Quinazoline derivatives, pyridopyrimidine derivatives, pyrimidopyrimidine derivatives, and uses thereof
|
|
WO2022219412A1
(en)
|
2021-04-14 |
2022-10-20 |
Monte Rosa Therapeutics Ag |
Isoindolinone amide compounds useful to treat diseases associated with gspt1
|
|
WO2022219407A1
(en)
|
2021-04-14 |
2022-10-20 |
Monte Rosa Therapeutics Ag |
Isoindolinone compounds
|
|
WO2022227015A1
(en)
|
2021-04-30 |
2022-11-03 |
Merck Sharp & Dohme Corp. |
Il4i1 inhibitors and methods of use
|
|
WO2023284730A1
(en)
|
2021-07-14 |
2023-01-19 |
Nikang Therapeutics, Inc. |
Alkylidene derivatives as kras inhibitors
|
|
JP2025509886A
(ja)
|
2022-03-28 |
2025-04-11 |
ニカング セラピューティクス, インコーポレイテッド |
サイクリン依存性キナーゼ2阻害剤としてのスルホンアミド誘導体
|
|
EP4536363A1
(en)
|
2022-06-08 |
2025-04-16 |
Nikang Therapeutics, Inc. |
Sulfamide derivatives as cyclin-dependent kinase 2 inhibitors
|
|
WO2024047112A1
(en)
*
|
2022-08-30 |
2024-03-07 |
Somtheranostics Sarl |
Halogenated somatostatin analogs with multiple somatostatin receptor subtype selectivity
|
|
AU2023375457A1
(en)
|
2022-11-11 |
2025-05-01 |
Nikang Therapeutics, Inc. |
Bifunctional compounds containing 2,5-substituted pyrimidine derivatives for degrading cyclin-dependent kinase 2 via ubiquitin proteasome pathway
|
|
WO2024206357A1
(en)
|
2023-03-29 |
2024-10-03 |
Merck Sharp & Dohme Llc |
Il4i1 inhibitors and methods of use
|
|
TW202502382A
(zh)
|
2023-06-30 |
2025-01-16 |
美商默沙東有限責任公司 |
治療組合及其用途和治療方法
|
|
WO2025072462A1
(en)
|
2023-09-27 |
2025-04-03 |
Nikang Therapeutics, Inc. |
Sulfonamide derivatives as cyclin-dependent kinase 2 inhibitors
|
|
TW202527955A
(zh)
|
2023-11-27 |
2025-07-16 |
美商尼坎醫療公司 |
用於經由泛素蛋白酶體途徑降解週期蛋白依賴性激酶2和週期蛋白依賴性激酶4的含有2,5-取代的嘧啶衍生物的雙功能化合物
|
|
WO2025117981A1
(en)
|
2023-12-02 |
2025-06-05 |
Nikang Therapeutics, Inc. |
Bifunctional compounds containing 2,5-substituted pyrimidine derivatives for degrading cyclin-dependent kinase 2 via ubiquitin proteasome pathway
|
|
WO2025212828A1
(en)
|
2024-04-03 |
2025-10-09 |
Nikang Therapeutics, Inc. |
Bifunctional compounds containing 2,5-substituted pyrimidine derivatives for degrading cyclin-dependent kinase 2 and cyclin-dependent kinase 4 via ubiquitin proteasome pathway
|
|
WO2025240536A1
(en)
|
2024-05-15 |
2025-11-20 |
Nikang Therapeutics, Inc. |
Bifunctional compounds containing 2,5-substituted pyrimidine derivatives for degrading cyclin-dependent kinase 2 and/or cyclin-dependent kinase 4 via ubiquitin proteasome pathway
|