BE1000355A3 - Composition pharmaceutique hydrosoluble contenant de la n-acetyl-cysteine et de l'acide citrique. - Google Patents

Composition pharmaceutique hydrosoluble contenant de la n-acetyl-cysteine et de l'acide citrique. Download PDF

Info

Publication number
BE1000355A3
BE1000355A3 BE8700816A BE8700816A BE1000355A3 BE 1000355 A3 BE1000355 A3 BE 1000355A3 BE 8700816 A BE8700816 A BE 8700816A BE 8700816 A BE8700816 A BE 8700816A BE 1000355 A3 BE1000355 A3 BE 1000355A3
Authority
BE
Belgium
Prior art keywords
citric acid
cysteine
acetyl
pharmaceutical composition
water
Prior art date
Application number
BE8700816A
Other languages
English (en)
Inventor
Annibale Gazzaniga
Valter Gianesello
Federico Stroppolo
Original Assignee
Inpharzam Internat Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inpharzam Internat Sa filed Critical Inpharzam Internat Sa
Application granted granted Critical
Publication of BE1000355A3 publication Critical patent/BE1000355A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Il est décrit une composition pharmaceutique, sous forme de granulé ou de comprimé effervescent hydrosoluble, constituée (en pourcentages en poids) par : N-acétyl-cystéine 6-32%;Acide citrique 35-50%;NaHCO3 26-37%;Aspartame 1-1,5%;Substance sapide 5-7%;le total s'élevant à 100% et le rapport en poids entre l'acide citrique et NaHCO3 étant compris entre 1,2 et 1,4.
BE8700816A 1986-07-24 1987-07-23 Composition pharmaceutique hydrosoluble contenant de la n-acetyl-cysteine et de l'acide citrique. BE1000355A3 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH2975/86A CH667590A5 (it) 1986-07-24 1986-07-24 Composizione farmaceutica effervescente idrosolubile contenente n-acetil-cisteina. .

Publications (1)

Publication Number Publication Date
BE1000355A3 true BE1000355A3 (fr) 1988-11-08

Family

ID=4245841

Family Applications (1)

Application Number Title Priority Date Filing Date
BE8700816A BE1000355A3 (fr) 1986-07-24 1987-07-23 Composition pharmaceutique hydrosoluble contenant de la n-acetyl-cysteine et de l'acide citrique.

Country Status (8)

Country Link
BE (1) BE1000355A3 (fr)
CH (1) CH667590A5 (fr)
DE (1) DE3723735A1 (fr)
FR (1) FR2601876B1 (fr)
GB (1) GB2192790B (fr)
IT (1) IT1222104B (fr)
NL (1) NL194067C (fr)
SE (1) SE500494C2 (fr)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1217445B (it) * 1988-04-29 1990-03-22 Altergon Sa Composizione farmaceutiche orosolubili contenti acetilcisteina
DE3822096A1 (de) * 1988-06-30 1990-01-04 Klinge Co Chem Pharm Fab Stabilisierte arzneimittelzubereitung
SE462779B (sv) * 1988-10-10 1990-09-03 Lejus Medical Ab Farmaceutisk komposition innehaallande n-acetylcystein i en kaerna belagd med hydroxipropylmetylcellulosaftalat
DE3909049A1 (de) * 1989-03-18 1990-09-20 Arthur Boskamp Praeparat und dessen verwendung
IT1231012B (it) * 1989-07-27 1991-11-08 Zambon Spa Composizione farmaceutica per uso orale contenente nac.
DE69209335T2 (de) * 1991-01-26 1996-08-29 Senju Pharma Co Mittel zur Zersetzung von Gallensteinen
DE4103360A1 (de) * 1991-02-05 1992-08-06 Koehler Peter Medikament zur linderung und heilung von asthma bronchiale und anderen lungenerkrankungen
US5296500A (en) * 1991-08-30 1994-03-22 The Procter & Gamble Company Use of N-acetyl-cysteine and derivatives for regulating skin wrinkles and/or skin atrophy
IT1256616B (it) * 1992-12-02 1995-12-12 Zambon Spa Sciroppo contenente n-acetil-cisteina
DE4406261C2 (de) * 1993-08-31 1996-07-04 Deutsches Krebsforsch Verwendung von Thiolverbindungen zur Verminderung der Körperfettmenge
BE1007926A3 (fr) * 1994-01-31 1995-11-21 Zambon Int Pharma Composition pharmaceutique contenant de la n-acetyl-cysteine.
US5451405A (en) * 1994-04-25 1995-09-19 Chesebrough-Pond's Usa Co. Skin treatment composition
DE19509856C2 (de) * 1995-03-17 1997-09-11 Schwabe Willmar Gmbh & Co Verwendung einer Brausezusammensetzung mit Ginkgo-Biloba Trockenextrakt zur Behandlung peripherer und cerebraler Durchblutungsstörungen
EP1115842A4 (fr) 1998-09-25 2002-08-21 Glycox Corp Ltd Dosage de fructosamine-oxydase: procedes et substances
CN1324234A (zh) 1998-09-25 2001-11-28 格利科克斯有限公司 果糖胺氧化酶,拮抗剂和抑制剂
WO2003077901A1 (fr) 2002-03-08 2003-09-25 Protemix Corporation Limited Prevention et/ou traitement de maladie cardio-vasculaire et/ou d'insuffisance cardiaque connexe
JP2006503014A (ja) 2002-08-20 2006-01-26 プロテミックス コーポレイション リミティド 剤形及び関連する治療法
ES2449066T3 (es) 2004-07-19 2014-03-18 Philera New Zealand Limited Síntesis de trietilentetraminas
TR200900881A2 (tr) * 2009-02-05 2010-08-23 Bi̇lgi̇ç Mahmut Tadı ve kokusu maskelenmiş stabil farmasötik bileşimler
TR200900882A2 (tr) * 2009-02-05 2010-08-23 Bi̇lgi̇ç Mahmut Tadı ve kokusu maskelenmiş, bıyoyararlanımı yüksek farmasotık bileşimler.
IT1399492B1 (it) 2010-04-13 2013-04-19 Alpex Pharma Sa Composizioni farmaceutiche effervescenti contenenti n-acetilcisteina.
CN102233139B (zh) * 2010-04-21 2012-09-05 重庆健能医药开发有限公司 一种乙酰半胱氨酸泡腾片及其制备方法和应用
EP2571499A1 (fr) * 2010-05-18 2013-03-27 Mahmut Bilgic Composition pharmaceutique contenant de la n- acétylcystéine et une xanthine
CN101947211A (zh) * 2010-08-28 2011-01-19 浙江金华康恩贝生物制药有限公司 一种乙酰半胱氨酸泡腾片的制备方法
TR201104738A2 (tr) * 2011-05-16 2012-12-21 Bi̇lgi̇ç Mahmut N-Asetilsistein içeren farmasötik kombinasyon.
US8747894B2 (en) * 2012-05-08 2014-06-10 Alpex Pharma S.A. Effervescent compositions containing N-acetylcysteine
EP2905020A1 (fr) 2014-02-05 2015-08-12 Sanovel Ilac Sanayi ve Ticaret A.S. Formulations effervescentes comprenant de l'ibuprofène et de la N-acétylecystéine
CN113559078A (zh) * 2021-07-02 2021-10-29 安徽省先锋制药有限公司 一种乙酰半胱氨酸泡腾片的制备方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2470M (fr) * 1962-03-13 1964-04-20 Mead Johnson & Co Composition thérapeutique.
FR2145590A1 (fr) * 1971-07-12 1973-02-23 Hoffmann La Roche

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3317558A1 (de) * 1983-05-13 1984-11-15 Dietrich Dr.med. Sta. Eulalia Ibiza Reichert Orales antischnarchmittel
DE3317530A1 (de) * 1983-05-13 1984-11-15 Dietrich Dr.med. Sta. Eulalia Ibiza Reichert Antischnarchmittel
IT1170268B (it) * 1983-12-21 1987-06-03 Zambon Spa Uso dell'acetilcisteina per ridurre l'incremento della prolieferazione delle cellule basali dell'epitelio respiratoriotracheo-bronchiale indotto dal fumo di tabacco nei mammiferi
DE3514995A1 (de) * 1985-04-25 1986-10-30 Protopharma Ltd., 7831 Malterdingen Verwendung von sulfydrylarzneimitteln zur bekaempfung von schaedigungen der magenschleimhaut

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2470M (fr) * 1962-03-13 1964-04-20 Mead Johnson & Co Composition thérapeutique.
FR2145590A1 (fr) * 1971-07-12 1973-02-23 Hoffmann La Roche

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DICTIONNAIRE VIDAL, 61ième édition, 1985, page 944, OVP, Paris, FR; "Mucomyst forme orale" *

Also Published As

Publication number Publication date
SE8702940D0 (sv) 1987-07-23
NL194067B (nl) 2001-02-01
FR2601876A1 (fr) 1988-01-29
DE3723735A1 (de) 1988-02-04
SE8702940L (sv) 1988-01-25
NL194067C (nl) 2001-06-05
CH667590A5 (it) 1988-10-31
IT8721411A0 (it) 1987-07-23
GB2192790A (en) 1988-01-27
IT1222104B (it) 1990-08-31
FR2601876B1 (fr) 1989-10-13
DE3723735C2 (fr) 1992-05-21
GB8717582D0 (en) 1987-09-03
GB2192790B (en) 1990-01-31
SE500494C2 (sv) 1994-07-04
NL8701743A (nl) 1988-02-16

Similar Documents

Publication Publication Date Title
BE1000355A3 (fr) Composition pharmaceutique hydrosoluble contenant de la n-acetyl-cysteine et de l'acide citrique.
BE904446A (fr) Compositions de ciment dentaire.
BE1002109A3 (fr) Composition pharmaceutique a activite analgesique.
FR2442054A1 (fr) Proteines purifiees, notamment interferon, procede de preparation et compositions pharmaceutiques les contenant
FR2378523A1 (fr) Medicament pour le traitement de l'acne
KR870006896A (ko) 서방성 약제학적 제제의 제조방법
FR2634376B1 (fr) Nouvelle forme unitaire, solide et poreuse comprenant des microparticules et/ou des nanoparticules, ainsi que sa preparation
MA25284A1 (fr) Composition antioxydante, y compris l'acide de l'acetylene, l-carnitine qui ameliore l'utilisation metabolique du glucose.
BE901994A (fr) Comprimes de principes actifs pharmaceutiques a delitement rapide, stables au stockage.
FR2653336B1 (fr) Composition pharmaceutique et cosmetiques depigmentantes a base d'acide cafeique.
BE904830A (fr) Nouvelle composition d'activateur tissulaire du plasminogene.
FR2601875B1 (fr) Composition pharmaceutique hydrosoluble contenant de la n-acetyl-cysteine et du sorbitol
FR2425245A1 (fr) Procede pour la preparation d'une composition injectable d'urokinase
FR2581310B1 (fr) Composition therapeutique comportant de l'acide a-linolenique et un compose susceptible de favoriser le passage de l'acide au travers de la membrane cellulaire et extrait de plantes comprenant l'acide et le compose
FR2432276A1 (fr) Produit dietetique hypo-beta-lipoproteinemique et sa preparation
CA2001359A1 (fr) Methode de traitement et de prevention de la pneumonie a pneumocystis carinii et d'autres maladies et formules utilisees dans cette methode
BE904625A (fr) Preparation dentaire a base d'emulsanne.
GR3002835T3 (en) Pharmaceutical compositions containing pentamidine
DE59910906D1 (de) Halbfeste wässrige zubereitungen für orale applikation von toltrazuril-sulfon
BE1002178A5 (fr) Produit de confiserie en substance gelatineuse.
BE902796A (fr) Ester d'acetyl carnitine, sa preparation et son utilisation.
BE901404A (fr) Procede d'inhibition de la plaque dentaire et de la gingivite.
FR2712809B1 (fr) Nouvelle composition pharmaceutique destinée à la préparation d'une poudre stable contenant, à titre d'ingrédient actif, une association d'acide acétylsalicylique et de métoclopramide.
WO1991015200A3 (fr) Utilisation trinitrobenzenes ou d'acide carminique pour le traitement du cancer ou de maladies virales
MA20303A1 (fr) Composition nutritive contenant de l'acide alpha-cetoisocaproique, de la leucine et des acides amines essentiels et non essentiels.

Legal Events

Date Code Title Description
RE20 Patent expired

Owner name: S.A. *INPHARZAM

Effective date: 20070723