AU745576B2 - Tetrazole-containing rapamycin analogs with shortened half-lives - Google Patents

Tetrazole-containing rapamycin analogs with shortened half-lives Download PDF

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Publication number
AU745576B2
AU745576B2 AU95819/98A AU9581998A AU745576B2 AU 745576 B2 AU745576 B2 AU 745576B2 AU 95819/98 A AU95819/98 A AU 95819/98A AU 9581998 A AU9581998 A AU 9581998A AU 745576 B2 AU745576 B2 AU 745576B2
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mammal
treatment
need
inhibiting
pharmaceutical composition
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AU95819/98A
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AU9581998A (en
Inventor
Karl W. Mollison
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Abbott Laboratories
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Abbott Laboratories
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Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of AU9581998A publication Critical patent/AU9581998A/en
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Publication of AU745576B2 publication Critical patent/AU745576B2/en
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Transplantation (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AU95819/98A 1997-09-26 1998-09-24 Tetrazole-containing rapamycin analogs with shortened half-lives Expired AU745576B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US93814497A 1997-09-26 1997-09-26
US08/938144 1997-09-26
PCT/US1998/020111 WO1999015530A1 (en) 1997-09-26 1998-09-24 Tetrazole-containing rapamycin analogs with shortened half-lives

Publications (2)

Publication Number Publication Date
AU9581998A AU9581998A (en) 1999-04-12
AU745576B2 true AU745576B2 (en) 2002-03-21

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ID=25470968

Family Applications (1)

Application Number Title Priority Date Filing Date
AU95819/98A Expired AU745576B2 (en) 1997-09-26 1998-09-24 Tetrazole-containing rapamycin analogs with shortened half-lives

Country Status (28)

Country Link
EP (1) EP1015459B9 (zh)
JP (1) JP3790424B2 (zh)
KR (3) KR100833812B1 (zh)
CN (1) CN1161360C (zh)
AR (1) AR015940A1 (zh)
AT (1) ATE297398T1 (zh)
AU (1) AU745576B2 (zh)
BG (1) BG64955B1 (zh)
BR (1) BR9812305A (zh)
CA (1) CA2303934C (zh)
CO (1) CO5070656A1 (zh)
CZ (1) CZ299365B6 (zh)
DE (1) DE69830502T2 (zh)
DK (1) DK1015459T3 (zh)
ES (1) ES2244087T3 (zh)
HK (1) HK1030771A1 (zh)
HU (1) HU228368B1 (zh)
IL (2) IL134607A0 (zh)
NO (1) NO325813B1 (zh)
NZ (2) NZ514778A (zh)
PL (1) PL191212B1 (zh)
PT (1) PT1015459E (zh)
SI (1) SI1015459T1 (zh)
SK (1) SK285408B6 (zh)
TR (1) TR200000778T2 (zh)
TW (1) TW557297B (zh)
WO (1) WO1999015530A1 (zh)
ZA (1) ZA988750B (zh)

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NZ502896A (en) 2001-12-21
CN1271361A (zh) 2000-10-25
KR100833812B1 (ko) 2008-05-30
PT1015459E (pt) 2005-09-30
PL191212B1 (pl) 2006-03-31
NZ514778A (en) 2005-01-28
EP1015459B1 (en) 2005-06-08
IL134607A (en) 2006-04-10
CN1161360C (zh) 2004-08-11
WO1999015530A1 (en) 1999-04-01
SI1015459T1 (en) 2005-10-31
CO5070656A1 (es) 2001-08-28
JP2001517671A (ja) 2001-10-09
BR9812305A (pt) 2000-09-05
DE69830502D1 (de) 2005-07-14
HUP0004556A2 (hu) 2001-10-28
SK285408B6 (sk) 2007-01-04
NO325813B1 (no) 2008-07-21
BG64955B1 (bg) 2006-10-31
KR100700319B1 (ko) 2007-03-29
CZ20001014A3 (cs) 2000-07-12
HUP0004556A3 (en) 2001-12-28
EP1015459B9 (en) 2005-10-12
ATE297398T1 (de) 2005-06-15
JP3790424B2 (ja) 2006-06-28
ES2244087T3 (es) 2005-12-01
NO20001438D0 (no) 2000-03-20
KR100803639B1 (ko) 2008-02-19
HK1030771A1 (en) 2001-05-18
TR200000778T2 (tr) 2000-07-21
IL134607A0 (en) 2001-04-30
KR20010024298A (ko) 2001-03-26
HU228368B1 (en) 2013-03-28
AU9581998A (en) 1999-04-12
CZ299365B6 (cs) 2008-07-02
KR20070086925A (ko) 2007-08-27
NO20001438L (no) 2000-05-26
EP1015459A1 (en) 2000-07-05
PL339455A1 (en) 2000-12-18
AR015940A1 (es) 2001-05-30
TW557297B (en) 2003-10-11
ZA988750B (en) 1999-04-01
BG104316A (en) 2000-12-29
CA2303934A1 (en) 1999-04-01
DK1015459T3 (da) 2005-10-10
CA2303934C (en) 2010-01-26
KR20060071092A (ko) 2006-06-26
SK4172000A3 (en) 2000-08-14
DE69830502T2 (de) 2006-05-11

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