AU717330B2 - Methods and compositions for detecting binding of ligand pair using non-fluorescent label - Google Patents

Methods and compositions for detecting binding of ligand pair using non-fluorescent label Download PDF

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Publication number
AU717330B2
AU717330B2 AU17079/97A AU1707997A AU717330B2 AU 717330 B2 AU717330 B2 AU 717330B2 AU 17079/97 A AU17079/97 A AU 17079/97A AU 1707997 A AU1707997 A AU 1707997A AU 717330 B2 AU717330 B2 AU 717330B2
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AU
Australia
Prior art keywords
acid
tag
group
alkyl
moi
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU17079/97A
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English (en)
Other versions
AU1707997A (en
Inventor
J. Jeffry Howbert
John T. Mulligan
John C. Tabone
Jeffrey Van Ness
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Qiagen Genomics Inc
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Rapigene Inc
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Filing date
Publication date
Application filed by Rapigene Inc filed Critical Rapigene Inc
Publication of AU1707997A publication Critical patent/AU1707997A/en
Application granted granted Critical
Publication of AU717330B2 publication Critical patent/AU717330B2/en
Assigned to QIAGEN GENOMICS, INC. reassignment QIAGEN GENOMICS, INC. Request to Amend Deed and Register Assignors: RAPIGENE, INC.
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/167—Mass label
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
    • C12Q2565/60—Detection means characterised by use of a special device
    • C12Q2565/627—Detection means characterised by use of a special device being a mass spectrometer
AU17079/97A 1996-01-23 1997-01-23 Methods and compositions for detecting binding of ligand pair using non-fluorescent label Ceased AU717330B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US1043696P 1996-01-23 1996-01-23
US60/010436 1996-01-23
US1540296P 1996-03-21 1996-03-21
US60/015402 1996-03-21
PCT/US1997/001070 WO1997027327A2 (en) 1996-01-23 1997-01-23 Methods and compositions for detecting binding of ligand pair using non-fluorescent label

Publications (2)

Publication Number Publication Date
AU1707997A AU1707997A (en) 1997-08-20
AU717330B2 true AU717330B2 (en) 2000-03-23

Family

ID=26681173

Family Applications (1)

Application Number Title Priority Date Filing Date
AU17079/97A Ceased AU717330B2 (en) 1996-01-23 1997-01-23 Methods and compositions for detecting binding of ligand pair using non-fluorescent label

Country Status (17)

Country Link
EP (1) EP0850320B1 (zh)
JP (2) JP2000507091A (zh)
KR (2) KR100473903B1 (zh)
CN (2) CN1159452C (zh)
AT (1) ATE187501T1 (zh)
AU (1) AU717330B2 (zh)
BR (1) BR9707060A (zh)
CA (1) CA2243989A1 (zh)
CZ (1) CZ218398A3 (zh)
DE (1) DE69700902T2 (zh)
ES (1) ES2143848T3 (zh)
GR (1) GR3032843T3 (zh)
HU (1) HUP9900459A3 (zh)
NZ (1) NZ331042A (zh)
PL (1) PL328272A1 (zh)
PT (1) PT850320E (zh)
WO (1) WO1997027327A2 (zh)

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Also Published As

Publication number Publication date
JP2000507091A (ja) 2000-06-13
NZ331042A (en) 1999-10-28
AU1707997A (en) 1997-08-20
CZ218398A3 (cs) 1998-12-16
EP0850320B1 (en) 1999-12-08
EP0850320A2 (en) 1998-07-01
KR19990081923A (ko) 1999-11-15
JP2008220370A (ja) 2008-09-25
CN1159452C (zh) 2004-07-28
ES2143848T3 (es) 2000-05-16
WO1997027327A2 (en) 1997-07-31
ATE187501T1 (de) 1999-12-15
KR20040081811A (ko) 2004-09-22
CN1515541A (zh) 2004-07-28
DE69700902T2 (de) 2000-07-20
BR9707060A (pt) 1999-12-28
CN1212019A (zh) 1999-03-24
DE69700902D1 (de) 2000-01-13
GR3032843T3 (en) 2000-07-31
WO1997027327A3 (en) 1997-11-20
PT850320E (pt) 2000-05-31
CA2243989A1 (en) 1997-07-31
PL328272A1 (en) 1999-01-18
HUP9900459A2 (hu) 1999-06-28
KR100473903B1 (ko) 2005-09-30
KR100538669B1 (ko) 2005-12-26
HUP9900459A3 (en) 1999-11-29

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HB Alteration of name in register

Owner name: QIAGEN GENOMICS, INC.

Free format text: FORMER NAME WAS: RAPIGENE, INC.