AU715748B2 - Taxane derivatives, the preparation thereof and formulations containing them - Google Patents

Taxane derivatives, the preparation thereof and formulations containing them Download PDF

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Publication number
AU715748B2
AU715748B2 AU28886/97A AU2888697A AU715748B2 AU 715748 B2 AU715748 B2 AU 715748B2 AU 28886/97 A AU28886/97 A AU 28886/97A AU 2888697 A AU2888697 A AU 2888697A AU 715748 B2 AU715748 B2 AU 715748B2
Authority
AU
Australia
Prior art keywords
hydrogen
deacetyl
formula
residue
iii
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU28886/97A
Other languages
English (en)
Other versions
AU2888697A (en
Inventor
Ezio Bombardelli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Indena SpA
Original Assignee
Indena SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena SpA filed Critical Indena SpA
Publication of AU2888697A publication Critical patent/AU2888697A/en
Application granted granted Critical
Publication of AU715748B2 publication Critical patent/AU715748B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/18—Bridged systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU28886/97A 1996-05-10 1997-04-29 Taxane derivatives, the preparation thereof and formulations containing them Ceased AU715748B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT96MI000942A IT1283633B1 (it) 1996-05-10 1996-05-10 Derivati tassanici loro sintesi e formulazioni che li contengono
ITMI96A000942 1996-05-10
PCT/EP1997/002198 WO1997043291A1 (fr) 1996-05-10 1997-04-29 Derives de taxane, leur preparation et formulations les contenant

Publications (2)

Publication Number Publication Date
AU2888697A AU2888697A (en) 1997-12-05
AU715748B2 true AU715748B2 (en) 2000-02-10

Family

ID=11374240

Family Applications (1)

Application Number Title Priority Date Filing Date
AU28886/97A Ceased AU715748B2 (en) 1996-05-10 1997-04-29 Taxane derivatives, the preparation thereof and formulations containing them

Country Status (21)

Country Link
US (1) US5955489A (fr)
EP (1) EP0901492B1 (fr)
JP (1) JP3423002B2 (fr)
KR (1) KR100314382B1 (fr)
CN (1) CN1097055C (fr)
AT (1) ATE220680T1 (fr)
AU (1) AU715748B2 (fr)
CA (1) CA2253912C (fr)
CZ (1) CZ287489B6 (fr)
DE (1) DE69714040T2 (fr)
DK (1) DK0901492T3 (fr)
ES (1) ES2180985T3 (fr)
HK (1) HK1019603A1 (fr)
HU (1) HU224965B1 (fr)
IT (1) IT1283633B1 (fr)
NO (1) NO322266B1 (fr)
PL (1) PL185778B1 (fr)
PT (1) PT901492E (fr)
RU (1) RU2168513C2 (fr)
SK (1) SK282471B6 (fr)
WO (1) WO1997043291A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003026673A (ja) * 1999-03-05 2003-01-29 Asahi Kasei Corp 骨形成促進剤
EP2266607A3 (fr) 1999-10-01 2011-04-20 Immunogen, Inc. Des immunoconjugués pour le traitement des cancers.
ITMI20012186A1 (it) * 2001-10-19 2003-04-19 Indena Spa Procedimento per la preparazione della 14-beta-idrossi-baccatina iii-1,14-carbonato
ITMI20012185A1 (it) * 2001-10-19 2003-04-19 Indena Spa Procedimento per la preparazione della 14beta-idrossi-baccatina iii-1,14-carbonato
EP1883627B1 (fr) 2005-05-18 2018-04-18 Pharmascience Inc. Composes liants de domaine bir
CN101535300B (zh) 2006-05-16 2014-05-28 埃格拉医疗公司 Iap bir域结合化合物
ES2389518T3 (es) 2008-01-18 2012-10-26 Indena S.P.A. Formas sólidas de ortataxel
NZ602368A (en) 2010-02-12 2014-10-31 Pharmascience Inc Iap bir domain binding compounds
CN113603660B (zh) * 2021-09-02 2024-01-05 无锡紫杉药业有限公司 一种10-羰基多西他赛的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601785B1 (fr) * 1986-07-15 1989-07-28 Telecommunications Sa Dispositif de reserve pour cable a fibre optique et le procede de mise en oeuvre
FR2601675B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
US5393886A (en) * 1993-05-05 1995-02-28 The Du Pont Merck Pharmaceutical Company Intermediates for the synthesis of anthrapyrazolone anticancer agents
IT1275936B1 (it) * 1995-03-17 1997-10-24 Indena Spa Derivati della 10-deacetilbaccatina iii e della 10-deacetil-14b- idrossibaccatina iii loro metodo di preparazione e formulazioni
IT1275435B (it) * 1995-05-19 1997-08-07 Indena Spa Derivati della 10-desacetil-14beta-idrossibaccatina iii,loro metodo di preparazione e formulazioni che li contengono

Also Published As

Publication number Publication date
CZ287489B6 (en) 2000-12-13
ATE220680T1 (de) 2002-08-15
AU2888697A (en) 1997-12-05
HUP9903649A3 (en) 2001-06-28
NO985187D0 (no) 1998-11-06
SK153998A3 (en) 1999-04-13
KR20000010894A (ko) 2000-02-25
JP3423002B2 (ja) 2003-07-07
CZ361998A3 (cs) 1999-06-16
DE69714040D1 (de) 2002-08-22
US5955489A (en) 1999-09-21
CN1097055C (zh) 2002-12-25
CA2253912C (fr) 2006-03-28
RU2168513C2 (ru) 2001-06-10
DK0901492T3 (da) 2002-09-02
WO1997043291A1 (fr) 1997-11-20
HK1019603A1 (en) 2000-02-18
EP0901492B1 (fr) 2002-07-17
PL185778B1 (pl) 2003-07-31
ITMI960942A0 (fr) 1996-05-10
PL329768A1 (en) 1999-04-12
JP2000513716A (ja) 2000-10-17
KR100314382B1 (ko) 2002-02-28
ITMI960942A1 (it) 1997-11-10
PT901492E (pt) 2002-10-31
HU224965B1 (en) 2006-04-28
HUP9903649A2 (hu) 2001-05-28
NO985187L (no) 1998-11-06
CN1218475A (zh) 1999-06-02
CA2253912A1 (fr) 1997-11-20
DE69714040T2 (de) 2003-03-13
SK282471B6 (sk) 2002-02-05
NO322266B1 (no) 2006-09-04
EP0901492A1 (fr) 1999-03-17
IT1283633B1 (it) 1998-04-23
ES2180985T3 (es) 2003-02-16

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)