IT1283633B1 - Derivati tassanici loro sintesi e formulazioni che li contengono - Google Patents

Derivati tassanici loro sintesi e formulazioni che li contengono

Info

Publication number
IT1283633B1
IT1283633B1 IT96MI000942A ITMI960942A IT1283633B1 IT 1283633 B1 IT1283633 B1 IT 1283633B1 IT 96MI000942 A IT96MI000942 A IT 96MI000942A IT MI960942 A ITMI960942 A IT MI960942A IT 1283633 B1 IT1283633 B1 IT 1283633B1
Authority
IT
Italy
Prior art keywords
pct
derivatives
deacetyl
sec
hydroxy
Prior art date
Application number
IT96MI000942A
Other languages
English (en)
Inventor
Ezio Bombardelli
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Publication of ITMI960942A0 publication Critical patent/ITMI960942A0/it
Priority to IT96MI000942A priority Critical patent/IT1283633B1/it
Priority to PCT/EP1997/002198 priority patent/WO1997043291A1/en
Priority to SK1539-98A priority patent/SK282471B6/sk
Priority to EP97922918A priority patent/EP0901492B1/en
Priority to KR1019980709041A priority patent/KR100314382B1/ko
Priority to AT97922918T priority patent/ATE220680T1/de
Priority to CZ19983619A priority patent/CZ287489B6/cs
Priority to JP54044497A priority patent/JP3423002B2/ja
Priority to US09/155,959 priority patent/US5955489A/en
Priority to ES97922918T priority patent/ES2180985T3/es
Priority to DK97922918T priority patent/DK0901492T3/da
Priority to RU98122311/04A priority patent/RU2168513C2/ru
Priority to HU9903649A priority patent/HU224965B1/hu
Priority to CN97194491A priority patent/CN1097055C/zh
Priority to PT97922918T priority patent/PT901492E/pt
Priority to CA002253912A priority patent/CA2253912C/en
Priority to SI9730295T priority patent/SI0901492T1/xx
Priority to PL97329768A priority patent/PL185778B1/pl
Priority to DE69714040T priority patent/DE69714040T2/de
Priority to AU28886/97A priority patent/AU715748B2/en
Publication of ITMI960942A1 publication Critical patent/ITMI960942A1/it
Application granted granted Critical
Publication of IT1283633B1 publication Critical patent/IT1283633B1/it
Priority to NO19985187A priority patent/NO322266B1/no
Priority to HK99104797A priority patent/HK1019603A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/18—Bridged systems
IT96MI000942A 1996-05-10 1996-05-10 Derivati tassanici loro sintesi e formulazioni che li contengono IT1283633B1 (it)

Priority Applications (22)

Application Number Priority Date Filing Date Title
IT96MI000942A IT1283633B1 (it) 1996-05-10 1996-05-10 Derivati tassanici loro sintesi e formulazioni che li contengono
DK97922918T DK0901492T3 (da) 1996-05-10 1997-04-29 Taxanderivater, fremstillingen deraf og formuleringer indeholdende dem
HU9903649A HU224965B1 (en) 1996-05-10 1997-04-29 Taxane derivatives, the preparation thereof and medical formulations containing them
EP97922918A EP0901492B1 (en) 1996-05-10 1997-04-29 Taxane derivatives, the preparation thereof and formulations containing them
KR1019980709041A KR100314382B1 (ko) 1996-05-10 1997-04-29 탁센유도체들과그제조방법및이들을함유한제제
AT97922918T ATE220680T1 (de) 1996-05-10 1997-04-29 Taxane derivate, ihre herstellung und zusammensetzungen die sie enthalten
CZ19983619A CZ287489B6 (en) 1996-05-10 1997-04-29 Taxane derivatives, process of their preparation and pharmaceutical preparation containing thereof
JP54044497A JP3423002B2 (ja) 1996-05-10 1997-04-29 タキサン誘導体、その調製、及びそれを含有する処方物
US09/155,959 US5955489A (en) 1996-05-10 1997-04-29 Taxane derivatives, the preparation thereof and formulations containing them
ES97922918T ES2180985T3 (es) 1996-05-10 1997-04-29 Derivados de taxano, su preparacion y formulaciones que los contienen.
PCT/EP1997/002198 WO1997043291A1 (en) 1996-05-10 1997-04-29 Taxane derivatives, the preparation thereof and formulations containing them
RU98122311/04A RU2168513C2 (ru) 1996-05-10 1997-04-29 Производные таксана, способ их получения и фармацевтическая композиция
SK1539-98A SK282471B6 (sk) 1996-05-10 1997-04-29 Taxánové deriváty, spôsob ich prípravy, farmaceutický prostriedok s ich obsahom a ich použitie
CN97194491A CN1097055C (zh) 1996-05-10 1997-04-29 紫杉烷衍生物,其制备方法以及含有它们的制剂
PT97922918T PT901492E (pt) 1996-05-10 1997-04-29 Derivados do taxano, processo para a sua preparacao e as formulacoes que os contem
CA002253912A CA2253912C (en) 1996-05-10 1997-04-29 Taxane derivatives, the preparation thereof and formulations containing them
SI9730295T SI0901492T1 (en) 1996-05-10 1997-04-29 Taxane derivatives, the preparation thereof and formulations containing them
PL97329768A PL185778B1 (pl) 1996-05-10 1997-04-29 Pochodne taksanu, sposób ich wytwarzania, kompozycja farmaceutyczna oraz ich zastosowanie
DE69714040T DE69714040T2 (de) 1996-05-10 1997-04-29 Taxane derivate, ihre herstellung und zusammensetzungen die sie enthalten
AU28886/97A AU715748B2 (en) 1996-05-10 1997-04-29 Taxane derivatives, the preparation thereof and formulations containing them
NO19985187A NO322266B1 (no) 1996-05-10 1998-11-06 Taxanderivater, deres fremstilling og formuleringer som inneholder dem
HK99104797A HK1019603A1 (en) 1996-05-10 1999-10-27 Taxane derivatives, the preparation thereof and formulations containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT96MI000942A IT1283633B1 (it) 1996-05-10 1996-05-10 Derivati tassanici loro sintesi e formulazioni che li contengono

Publications (3)

Publication Number Publication Date
ITMI960942A0 ITMI960942A0 (it) 1996-05-10
ITMI960942A1 ITMI960942A1 (it) 1997-11-10
IT1283633B1 true IT1283633B1 (it) 1998-04-23

Family

ID=11374240

Family Applications (1)

Application Number Title Priority Date Filing Date
IT96MI000942A IT1283633B1 (it) 1996-05-10 1996-05-10 Derivati tassanici loro sintesi e formulazioni che li contengono

Country Status (21)

Country Link
US (1) US5955489A (it)
EP (1) EP0901492B1 (it)
JP (1) JP3423002B2 (it)
KR (1) KR100314382B1 (it)
CN (1) CN1097055C (it)
AT (1) ATE220680T1 (it)
AU (1) AU715748B2 (it)
CA (1) CA2253912C (it)
CZ (1) CZ287489B6 (it)
DE (1) DE69714040T2 (it)
DK (1) DK0901492T3 (it)
ES (1) ES2180985T3 (it)
HK (1) HK1019603A1 (it)
HU (1) HU224965B1 (it)
IT (1) IT1283633B1 (it)
NO (1) NO322266B1 (it)
PL (1) PL185778B1 (it)
PT (1) PT901492E (it)
RU (1) RU2168513C2 (it)
SK (1) SK282471B6 (it)
WO (1) WO1997043291A1 (it)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003026673A (ja) * 1999-03-05 2003-01-29 Asahi Kasei Corp 骨形成促進剤
CA2385528C (en) 1999-10-01 2013-12-10 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
ITMI20012185A1 (it) * 2001-10-19 2003-04-19 Indena Spa Procedimento per la preparazione della 14beta-idrossi-baccatina iii-1,14-carbonato
ITMI20012186A1 (it) * 2001-10-19 2003-04-19 Indena Spa Procedimento per la preparazione della 14-beta-idrossi-baccatina iii-1,14-carbonato
EP1883627B1 (en) 2005-05-18 2018-04-18 Pharmascience Inc. Bir domain binding compounds
EP2024362A4 (en) 2006-05-16 2012-01-25 Pharmascience Inc IAP BIR DOMAIN BINDING COMPOUNDS
EP2080764B1 (en) 2008-01-18 2012-08-22 INDENA S.p.A. Solid forms of ortataxel
AU2011214057B2 (en) 2010-02-12 2016-11-17 Pharmascience Inc. IAP BIR domain binding compounds
CN113603660B (zh) * 2021-09-02 2024-01-05 无锡紫杉药业有限公司 一种10-羰基多西他赛的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601785B1 (fr) * 1986-07-15 1989-07-28 Telecommunications Sa Dispositif de reserve pour cable a fibre optique et le procede de mise en oeuvre
FR2601675B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
US5393886A (en) * 1993-05-05 1995-02-28 The Du Pont Merck Pharmaceutical Company Intermediates for the synthesis of anthrapyrazolone anticancer agents
IT1275936B1 (it) * 1995-03-17 1997-10-24 Indena Spa Derivati della 10-deacetilbaccatina iii e della 10-deacetil-14b- idrossibaccatina iii loro metodo di preparazione e formulazioni
IT1275435B (it) * 1995-05-19 1997-08-07 Indena Spa Derivati della 10-desacetil-14beta-idrossibaccatina iii,loro metodo di preparazione e formulazioni che li contengono

Also Published As

Publication number Publication date
CA2253912A1 (en) 1997-11-20
EP0901492B1 (en) 2002-07-17
ITMI960942A0 (it) 1996-05-10
DE69714040T2 (de) 2003-03-13
PL329768A1 (en) 1999-04-12
KR20000010894A (ko) 2000-02-25
PL185778B1 (pl) 2003-07-31
ATE220680T1 (de) 2002-08-15
CA2253912C (en) 2006-03-28
HK1019603A1 (en) 2000-02-18
CZ361998A3 (cs) 1999-06-16
JP3423002B2 (ja) 2003-07-07
CZ287489B6 (en) 2000-12-13
RU2168513C2 (ru) 2001-06-10
AU2888697A (en) 1997-12-05
EP0901492A1 (en) 1999-03-17
SK153998A3 (en) 1999-04-13
CN1218475A (zh) 1999-06-02
SK282471B6 (sk) 2002-02-05
HUP9903649A2 (hu) 2001-05-28
US5955489A (en) 1999-09-21
CN1097055C (zh) 2002-12-25
HUP9903649A3 (en) 2001-06-28
ES2180985T3 (es) 2003-02-16
PT901492E (pt) 2002-10-31
HU224965B1 (en) 2006-04-28
DK0901492T3 (da) 2002-09-02
NO322266B1 (no) 2006-09-04
NO985187L (no) 1998-11-06
ITMI960942A1 (it) 1997-11-10
NO985187D0 (no) 1998-11-06
JP2000513716A (ja) 2000-10-17
WO1997043291A1 (en) 1997-11-20
KR100314382B1 (ko) 2002-02-28
DE69714040D1 (de) 2002-08-22
AU715748B2 (en) 2000-02-10

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Legal Events

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0001 Granted