AU714533B2 - DNA encoding human papilloma virus type 18 - Google Patents

DNA encoding human papilloma virus type 18 Download PDF

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Publication number
AU714533B2
AU714533B2 AU53141/96A AU5314196A AU714533B2 AU 714533 B2 AU714533 B2 AU 714533B2 AU 53141/96 A AU53141/96 A AU 53141/96A AU 5314196 A AU5314196 A AU 5314196A AU 714533 B2 AU714533 B2 AU 714533B2
Authority
AU
Australia
Prior art keywords
protein
dna molecule
recombinant
virus
papillomavirus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired, expires
Application number
AU53141/96A
Other languages
English (en)
Other versions
AU5314196A (en
Inventor
Hugh A George
Kathryn J Hofmann
Kathrin U Jansen
Joseph G Joyce
Michael P. Neeper
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27020342&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU714533(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/409,122 external-priority patent/US5820870A/en
Priority claimed from US08/408,669 external-priority patent/US5840306A/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of AU5314196A publication Critical patent/AU5314196A/en
Application granted granted Critical
Publication of AU714533B2 publication Critical patent/AU714533B2/en
Assigned to MERCK SHARP & DOHME CORP. reassignment MERCK SHARP & DOHME CORP. Request to Amend Deed and Register Assignors: MERCK & CO., INC.
Assigned to MERCK SHARP & DOHME CORP. reassignment MERCK SHARP & DOHME CORP. Request to Amend Deed and Register Assignors: MERCK SHARP & DOHME CORP.
Adjusted expiration legal-status Critical
Expired legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
    • C12N15/905—Stable introduction of foreign DNA into chromosome using homologous recombination in yeast
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
    • C12N9/60—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi from yeast
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20023—Virus like particles [VLP]

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU53141/96A 1995-03-22 1996-03-18 DNA encoding human papilloma virus type 18 Expired AU714533B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US08/409,122 US5820870A (en) 1995-03-22 1995-03-22 Recombinant human papillomavirus type 18 vaccine
US08/408669 1995-03-22
US08/409122 1995-03-22
US08/408,669 US5840306A (en) 1995-03-22 1995-03-22 DNA encoding human papillomavirus type 18
PCT/US1996/003649 WO1996029413A2 (en) 1995-03-22 1996-03-18 Dna encoding human papilloma virus type 18

Publications (2)

Publication Number Publication Date
AU5314196A AU5314196A (en) 1996-10-08
AU714533B2 true AU714533B2 (en) 2000-01-06

Family

ID=27020342

Family Applications (1)

Application Number Title Priority Date Filing Date
AU53141/96A Expired AU714533B2 (en) 1995-03-22 1996-03-18 DNA encoding human papilloma virus type 18

Country Status (22)

Country Link
EP (2) EP1422294A1 (OSRAM)
JP (1) JPH11502704A (OSRAM)
KR (1) KR100430698B1 (OSRAM)
CN (1) CN1100876C (OSRAM)
AT (1) ATE259879T1 (OSRAM)
AU (1) AU714533B2 (OSRAM)
CA (1) CA2215834C (OSRAM)
CZ (1) CZ291242B6 (OSRAM)
DE (4) DE122007000025I1 (OSRAM)
DK (1) DK0817851T5 (OSRAM)
EA (1) EA001092B1 (OSRAM)
ES (1) ES2213772T3 (OSRAM)
FR (1) FR07C0023I2 (OSRAM)
HU (1) HU223761B1 (OSRAM)
IL (1) IL117459A (OSRAM)
NL (3) NL300273I1 (OSRAM)
NO (1) NO322254B1 (OSRAM)
NZ (1) NZ305188A (OSRAM)
PL (1) PL184022B1 (OSRAM)
PT (1) PT817851E (OSRAM)
SK (1) SK284281B6 (OSRAM)
WO (1) WO1996029413A2 (OSRAM)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9621091D0 (en) 1996-10-09 1996-11-27 Fondation Pour Le Perfectionem Attenuated microorganisms strains and their uses
ZA982950B (en) 1997-04-08 1998-10-19 Merck & Co Inc Stabilized human papillomavirus formulations
IL132201A0 (en) * 1997-04-08 2001-03-19 Merck & Co Inc Stabilized human papillomavirus formulations
DE69931053T2 (de) * 1998-08-14 2006-11-23 Merck & Co., Inc. Verfahren zur reinigung von menschlichen, dem papillomavirus ähnlichen partikeln.
AUPP765398A0 (en) * 1998-12-11 1999-01-14 University Of Queensland, The Treatment of papillomavirus infections
EP1150712B1 (en) 1999-02-05 2008-11-05 Merck & Co., Inc. Human papilloma virus vaccine formulations
FR2795074A1 (fr) * 1999-05-21 2000-12-22 Inst Nat Sante Rech Med Polypeptides transporteurs d'acides amines, et en particulier du glutamate, et procedes de criblage de composes inhibiteurs ou activateurs de l'activite de transport
MXPA05010285A (es) * 2003-03-24 2005-11-17 Merck & Co Inc Expresion optimizada de hpv 31 l1 en levadura.
MY140664A (en) * 2003-09-29 2010-01-15 Merck Sharp & Dohme Optimized expression of hpv 45 l1 in yeast
TWI457133B (zh) 2005-12-13 2014-10-21 Glaxosmithkline Biolog Sa 新穎組合物
US9364529B2 (en) 2007-04-29 2016-06-14 Beijing Wantai Biological Pharmacy Enterprise Co., Ltd. Truncated L1 protein of human papillomavirus type 18
CN101293918B (zh) 2007-04-29 2013-03-27 北京万泰生物药业股份有限公司 截短的人乳头瘤病毒16型l1蛋白
CN101440373B (zh) * 2007-11-23 2012-09-05 上海泽润生物科技有限公司 一种截短型的18型人乳头状瘤病毒主要衣壳蛋白l1基因
US20120087937A1 (en) * 2009-06-25 2012-04-12 Brigitte Desiree Alberte Colau Novel compositions
CA2839427C (en) * 2011-06-15 2016-09-27 Chung-Ang University Industry-Academic Cooperation Foundation Method for enhancing the production yield of human papillomavirus l1 protein
US20150110824A1 (en) 2012-03-18 2015-04-23 Glaxosmithkline Biologicals, Sa Method of vaccination against human papillomavirus
CN108276491B (zh) * 2018-02-05 2021-01-12 南京薇熙生物医药科技有限公司 一种可特异性识别hpv18 l1蛋白的单克隆抗体及其应用
MX2022000778A (es) 2019-07-19 2022-02-14 Sinocelltech Ltd Proteina quimerica l1 del virus de papiloma humano.
EP4302741B1 (en) 2022-07-07 2025-01-29 Permobil AB Powered midwheel drive wheelchair with standing capability

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994005792A1 (en) * 1992-09-03 1994-03-17 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Self-assembling recombinant papillomavirus capsid proteins
WO1994020137A1 (en) * 1993-03-09 1994-09-15 University Of Rochester Production of human papillomavirus capsid protein and virus-like particles

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3625257A1 (de) * 1986-07-23 1988-02-04 Behringwerke Ag Expressionsprodukte der menschlichen papillomviren typ 16 und 18, fuer diese proteine spezifische antikoerper und diese antikoerper bzw. entsprechende dna enthaltende diagnostika
DE4015044A1 (de) * 1990-05-10 1991-11-14 Behringwerke Ag Seroreaktive epitope auf proteinen des menschlichen papillomavirus (hpv) 18
ES2279020T3 (es) * 1991-07-19 2007-08-16 The University Of Queensland Vacuna contra el papilomavirus humano.
EP0647140B1 (en) * 1992-06-25 2007-12-12 Georgetown University Papillomavirus vaccines

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994005792A1 (en) * 1992-09-03 1994-03-17 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Self-assembling recombinant papillomavirus capsid proteins
WO1994020137A1 (en) * 1993-03-09 1994-09-15 University Of Rochester Production of human papillomavirus capsid protein and virus-like particles

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
J VIROLOGY 67 P315-322(1993) *

Also Published As

Publication number Publication date
CN1100876C (zh) 2003-02-05
NL300272I1 (nl) 2007-05-01
CA2215834A1 (en) 1996-09-26
DE122007000031I1 (de) 2007-07-19
CZ291242B6 (cs) 2003-01-15
WO1996029413A2 (en) 1996-09-26
SK284281B6 (sk) 2004-12-01
CN1185176A (zh) 1998-06-17
IL117459A (en) 2005-11-20
NO974322L (no) 1997-11-24
PT817851E (pt) 2004-06-30
DE122007000030I1 (de) 2007-07-19
HU223761B1 (hu) 2005-01-28
NL300273I1 (nl) 2007-05-01
PL322333A1 (en) 1998-01-19
AU5314196A (en) 1996-10-08
PL184022B1 (pl) 2002-08-30
EP1422294A1 (en) 2004-05-26
DE122007000025I1 (de) 2007-07-12
DE69631586D1 (de) 2004-03-25
DE69631586T2 (de) 2005-01-27
DK0817851T3 (da) 2004-08-16
EA001092B1 (ru) 2000-10-30
HUP9801334A3 (en) 1999-04-28
MX9707208A (es) 1997-11-29
NL300271I1 (nl) 2007-05-01
SK127897A3 (en) 1998-07-08
ATE259879T1 (de) 2004-03-15
IL117459A0 (en) 1996-07-23
EP0817851B9 (en) 2004-08-18
KR100430698B1 (ko) 2004-07-15
FR07C0023I2 (fr) 2012-08-03
WO1996029413A3 (en) 1996-11-28
FR07C0023I1 (OSRAM) 2007-04-27
JPH11502704A (ja) 1999-03-09
CA2215834C (en) 2007-06-12
DE69631586T9 (de) 2005-06-16
HUP9801334A2 (hu) 1998-08-28
EP0817851B1 (en) 2004-02-18
NZ305188A (en) 1999-11-29
NO974322D0 (no) 1997-09-19
EA199700256A1 (ru) 1999-06-24
DK0817851T5 (da) 2004-10-25
CZ293697A3 (cs) 1998-02-18
EP0817851A2 (en) 1998-01-14
NO322254B1 (no) 2006-09-04
ES2213772T3 (es) 2004-09-01

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Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired