AU708076B2 - Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy - Google Patents

Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy Download PDF

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Publication number
AU708076B2
AU708076B2 AU49500/96A AU4950096A AU708076B2 AU 708076 B2 AU708076 B2 AU 708076B2 AU 49500/96 A AU49500/96 A AU 49500/96A AU 4950096 A AU4950096 A AU 4950096A AU 708076 B2 AU708076 B2 AU 708076B2
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AU
Australia
Prior art keywords
ala
fluorescence
skin
photochemotherapy
diagnosis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired, expires
Application number
AU49500/96A
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English (en)
Other versions
AU4950096A (en
Inventor
Alf Bjorseth
Karl Erik Gierskcky
Johan Moan
Qian Peng
Harald Steen
Trond Warloe
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Photocure ASA
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Photocure ASA
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26306657&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU708076(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9504948.2A external-priority patent/GB9504948D0/en
Priority claimed from GBGB9525822.4A external-priority patent/GB9525822D0/en
Application filed by Photocure ASA filed Critical Photocure ASA
Publication of AU4950096A publication Critical patent/AU4950096A/en
Application granted granted Critical
Publication of AU708076B2 publication Critical patent/AU708076B2/en
Assigned to PHOTOCURE ASA reassignment PHOTOCURE ASA Request to Amend Deed and Register Assignors: PHOTOCURE AS
Adjusted expiration legal-status Critical
Expired legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0061—5-aminolevulinic acid-based PDT: 5-ALA-PDT involving porphyrins or precursors of protoporphyrins generated in vivo from 5-ALA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/145555—Hetero-N

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU49500/96A 1995-03-10 1996-03-08 Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy Expired AU708076B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB9504948 1995-03-10
GBGB9504948.2A GB9504948D0 (en) 1995-03-10 1995-03-10 Compounds
GBGB9525822.4A GB9525822D0 (en) 1995-12-18 1995-12-18 Compounds
GB9525822 1995-12-18
PCT/GB1996/000553 WO1996028412A1 (en) 1995-03-10 1996-03-08 Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy

Publications (2)

Publication Number Publication Date
AU4950096A AU4950096A (en) 1996-10-02
AU708076B2 true AU708076B2 (en) 1999-07-29

Family

ID=26306657

Family Applications (1)

Application Number Title Priority Date Filing Date
AU49500/96A Expired AU708076B2 (en) 1995-03-10 1996-03-08 Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy

Country Status (19)

Country Link
US (1) US6034267A (enExample)
EP (1) EP0820432B1 (enExample)
JP (1) JP3955093B2 (enExample)
KR (1) KR100444007B1 (enExample)
CN (1) CN1137087C (enExample)
AT (1) ATE202076T1 (enExample)
AU (1) AU708076B2 (enExample)
CA (1) CA2215069C (enExample)
CZ (1) CZ291132B6 (enExample)
DE (3) DE122006000051I1 (enExample)
ES (1) ES2157424T3 (enExample)
FR (1) FR05C0042I2 (enExample)
HU (1) HU225148B1 (enExample)
LU (1) LU90956I2 (enExample)
NL (2) NL300176I1 (enExample)
NO (3) NO318379B1 (enExample)
NZ (1) NZ303251A (enExample)
PT (1) PT820432E (enExample)
WO (1) WO1996028412A1 (enExample)

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Also Published As

Publication number Publication date
HUP9800460A3 (en) 1998-08-28
ATE202076T1 (de) 2001-06-15
FR05C0042I2 (enExample) 2009-10-30
NO974163L (no) 1997-09-09
WO1996028412A1 (en) 1996-09-19
ES2157424T3 (es) 2001-08-16
CA2215069A1 (en) 1996-09-19
DE69613365T2 (de) 2002-05-02
NL300176I2 (nl) 2005-05-02
EP0820432B1 (en) 2001-06-13
DE122006000051I1 (de) 2007-01-04
US6034267A (en) 2000-03-07
FR05C0042I1 (enExample) 2005-02-12
EP0820432A1 (en) 1998-01-28
LU90956I2 (fr) 2002-11-13
DE69613365D1 (de) 2001-07-19
NL300207I2 (nl) 2005-12-01
NO2005019I1 (no) 2005-09-26
CZ291132B6 (cs) 2002-12-11
NO2005019I2 (no) 2007-04-23
NL300176I1 (nl) 2005-05-02
DE122006000051I2 (de) 2010-07-08
NO974163D0 (no) 1997-09-09
NL300207I1 (nl) 2005-12-01
JPH11501914A (ja) 1999-02-16
PT820432E (pt) 2001-09-28
CZ284897A3 (cs) 1998-03-18
AU4950096A (en) 1996-10-02
NO2005024I2 (no) 2007-04-23
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HUP9800460A2 (hu) 1998-07-28
NO318379B1 (no) 2005-03-14
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JP3955093B2 (ja) 2007-08-08
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