NO974163L - Ester av 5-aminolevulinsyre som fotosensibiliserings-middel i fotokjemoterapi - Google Patents

Ester av 5-aminolevulinsyre som fotosensibiliserings-middel i fotokjemoterapi

Info

Publication number
NO974163L
NO974163L NO974163A NO974163A NO974163L NO 974163 L NO974163 L NO 974163L NO 974163 A NO974163 A NO 974163A NO 974163 A NO974163 A NO 974163A NO 974163 L NO974163 L NO 974163L
Authority
NO
Norway
Prior art keywords
pct
photochemotherapy
photosensitizer
ester
aminolevulinic acid
Prior art date
Application number
NO974163A
Other languages
English (en)
Other versions
NO974163D0 (no
NO318379B1 (no
Inventor
Karl-Erik Gierskcky
Johan Moan
Qian Peng
Harald Steen
Trond Warloe
Alf Bjoerseth
Original Assignee
Photocure As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26306657&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO974163(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9504948.2A external-priority patent/GB9504948D0/en
Priority claimed from GBGB9525822.4A external-priority patent/GB9525822D0/en
Application filed by Photocure As filed Critical Photocure As
Publication of NO974163D0 publication Critical patent/NO974163D0/no
Publication of NO974163L publication Critical patent/NO974163L/no
Publication of NO318379B1 publication Critical patent/NO318379B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0061—5-aminolevulinic acid-based PDT: 5-ALA-PDT involving porphyrins or precursors of protoporphyrins generated in vivo from 5-ALA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/145555—Hetero-N

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO19974163A 1995-03-10 1997-09-09 Ester av 5-aminolevulinsyre som fotosensibiliseringsmiddel i fotokjemoterapi, anvendelse derav, samt farmasoytisk blanding, produkt, utstyrsett og fremgangsmate for in vitro-diagnostisering. NO318379B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9504948.2A GB9504948D0 (en) 1995-03-10 1995-03-10 Compounds
GBGB9525822.4A GB9525822D0 (en) 1995-12-18 1995-12-18 Compounds
PCT/GB1996/000553 WO1996028412A1 (en) 1995-03-10 1996-03-08 Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy

Publications (3)

Publication Number Publication Date
NO974163D0 NO974163D0 (no) 1997-09-09
NO974163L true NO974163L (no) 1997-09-09
NO318379B1 NO318379B1 (no) 2005-03-14

Family

ID=26306657

Family Applications (3)

Application Number Title Priority Date Filing Date
NO19974163A NO318379B1 (no) 1995-03-10 1997-09-09 Ester av 5-aminolevulinsyre som fotosensibiliseringsmiddel i fotokjemoterapi, anvendelse derav, samt farmasoytisk blanding, produkt, utstyrsett og fremgangsmate for in vitro-diagnostisering.
NO2005019C NO2005019I2 (no) 1995-03-10 2005-09-13 Metylaminolevulinat, eventuelt i form av et salt, fortrinnsvis metylaminolevulinat-hydroklorid
NO2005024C NO2005024I2 (no) 1995-03-10 2005-11-07 Ester av 5-aminolevulinsyre som fotosensibiliseringsmiddel i fotokjemoterapi, anvendelse derav, samtfarmasoytisk blanding, produkt, utstyrsett og fre mgangsmaate for in vitro-diagnostisering

Family Applications After (2)

Application Number Title Priority Date Filing Date
NO2005019C NO2005019I2 (no) 1995-03-10 2005-09-13 Metylaminolevulinat, eventuelt i form av et salt, fortrinnsvis metylaminolevulinat-hydroklorid
NO2005024C NO2005024I2 (no) 1995-03-10 2005-11-07 Ester av 5-aminolevulinsyre som fotosensibiliseringsmiddel i fotokjemoterapi, anvendelse derav, samtfarmasoytisk blanding, produkt, utstyrsett og fre mgangsmaate for in vitro-diagnostisering

Country Status (19)

Country Link
US (1) US6034267A (no)
EP (1) EP0820432B1 (no)
JP (1) JP3955093B2 (no)
KR (1) KR100444007B1 (no)
CN (1) CN1137087C (no)
AT (1) ATE202076T1 (no)
AU (1) AU708076B2 (no)
CA (1) CA2215069C (no)
CZ (1) CZ291132B6 (no)
DE (3) DE122006000051I2 (no)
ES (1) ES2157424T3 (no)
FR (1) FR05C0042I2 (no)
HU (1) HU225148B1 (no)
LU (1) LU90956I2 (no)
NL (2) NL300176I1 (no)
NO (3) NO318379B1 (no)
NZ (1) NZ303251A (no)
PT (1) PT820432E (no)
WO (1) WO1996028412A1 (no)

Families Citing this family (84)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6492420B2 (en) * 1995-03-10 2002-12-10 Photocure As Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US6992107B1 (en) * 1995-03-10 2006-01-31 Photocure Asa Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy
US7530461B2 (en) 1995-03-10 2009-05-12 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US5895786A (en) * 1996-05-08 1999-04-20 New York Blood Center, Inc. Method for treating viral infections
GB9700396D0 (en) 1997-01-10 1997-02-26 Photocure As Photochemotherapeutic compositions
FR2777782B1 (fr) * 1998-04-22 2001-05-18 Alexandre Marti Solution pour la preparation d'une substance pharmaceutique pour le diagnostic et/ou le traitement de lesions tissulaires
US6223071B1 (en) 1998-05-01 2001-04-24 Dusa Pharmaceuticals Inc. Illuminator for photodynamic therapy and diagnosis which produces substantially uniform intensity visible light
DE19852245A1 (de) * 1998-11-12 2000-05-18 Asat Ag Applied Science & Tech 5-Aminolävulinsäure-Nanoemulsion
EP1203096B1 (en) 1999-07-28 2008-12-31 Merck Serono Biodevelopment Continuous flow micro device in which local temperature cycles act on a flowing sample
JP3970492B2 (ja) * 1999-12-14 2007-09-05 コスモ石油株式会社 ピーリング用組成物
DE10003620A1 (de) * 2000-01-28 2001-08-02 Asat Ag Applied Science & Tech 5-Aminolävulinsäure-Formulierung in nichtwässrigen Lösungsmitteln
NO20002428D0 (no) 2000-05-10 2000-05-10 Radiumhospitalets Forskningsst Hudpreparat
US6454790B1 (en) * 2000-07-21 2002-09-24 Ceramoptec Industries, Inc. Treatment for Barrett's syndrome
GB0018528D0 (en) * 2000-07-27 2000-09-13 Photocure Asa Compounds
GB0018527D0 (en) * 2000-07-27 2000-09-13 Photocure Asa Composition
EP1318807A4 (en) * 2000-08-11 2008-02-20 Ceramoptec Gmbh LIGHT-SENSITIVE OINTMENT
EP1203944B1 (de) * 2000-11-06 2006-03-01 Hofstetter, Alfons, Prof.Dr.med. Tumorzellenidentifizierungsverfahren
US7223600B2 (en) * 2000-11-29 2007-05-29 The Norwegian Radium Hospital Research Foundation Photochemical internalization for delivery of molecules into the cytosol
CA2430334C (en) 2000-11-29 2018-08-21 Pci Biotech As Photochemical internalization for virus-mediated molecule delivery into the cytosol
EP1312353A1 (en) 2001-11-16 2003-05-21 Ecole Polytechnique Federale De Lausanne (Epfl) Method for hair removal
US6723750B2 (en) * 2002-03-15 2004-04-20 Allergan, Inc. Photodynamic therapy for pre-melanomas
US20040073277A1 (en) * 2002-04-05 2004-04-15 Geronemus Roy G. High fluence rate activation of photosensitizers for dermatological applications
DE10301917B4 (de) * 2003-01-17 2007-02-01 Gerhard Saalmann Verwendung von Substanzen der Porphyrinsynthese bei der Phototherapie von Haut- oder Gelenkerkrankungen des Menschen oder von Säugetieren
DE10312659A1 (de) * 2003-03-21 2004-10-07 Universität Regensburg 5-Aminolävulinsäurederivate und ihre Verwendung
US20050209331A1 (en) * 2004-03-22 2005-09-22 Syneron Medical Ltd. Method of treatment of skin
GB0406917D0 (en) 2004-03-26 2004-04-28 Photocure Asa Compounds
CN1942163B (zh) * 2004-04-28 2010-11-24 克斯莫石油公司 生发剂
JP2005350418A (ja) * 2004-06-11 2005-12-22 Shibuya Kogyo Co Ltd 標的細胞の死滅方法と標的細胞を死滅させるための薬剤及び該薬剤の製造装置
JP5034032B2 (ja) * 2004-09-29 2012-09-26 Ｓｂｉファーマ株式会社 腫瘍診断剤
GB0424833D0 (en) * 2004-11-10 2004-12-15 Photocure Asa Method
GB0515550D0 (en) 2005-07-29 2005-09-07 Univ Strathclyde Inactivation of staphylococcus species
US20070225518A1 (en) * 2006-03-22 2007-09-27 Zvi Malik 5-Aminolevulinic acid salts and their use
KR100796450B1 (ko) * 2006-06-29 2008-01-22 전남대학교산학협력단 5-아미노레불린산의 불포화 알킬 에스터 및 약학적으로허용되는 그의 염, 이의 제조방법 및 이의 용도
GB0700580D0 (en) * 2007-01-11 2007-02-21 Photocure Asa Use
JP5098051B2 (ja) 2007-04-05 2012-12-12 Ｓｂｉファーマ株式会社 ミトコンドリア障害脳疾患治療剤及び診断剤
GB0724279D0 (en) * 2007-12-12 2008-01-23 Photocure Asa Use
AU2014200004B2 (en) * 2007-12-12 2016-10-27 Photocure Asa Use of 5-aminolevulinic acid and derivatives in a solid form for photodynamic treatment and diagnosis
AU2008337067A1 (en) 2007-12-14 2009-06-25 Photoderma Sa Novel compounds useful in therapeutic and cosmetic methods
US8916502B2 (en) 2008-05-13 2014-12-23 Cosmo Oil Co., Ltd. Agent for improving lawn grass qualities
EP2305237B1 (en) 2008-05-14 2014-04-30 SBI Pharmaceuticals Co., Ltd. Therapeutic agent for male sterility
AU2009286182B2 (en) 2008-09-01 2013-11-07 Swedish Pharma Ab New 5-aminolevulinic acid prodrugs for use in photodynamic therapy and photodynamic diagnosis
CN101745102B (zh) * 2008-12-16 2013-08-07 上海复旦张江生物医药股份有限公司 5-氨基酮戊酸及其衍生物的组合物及其用途
GB0823472D0 (en) * 2008-12-23 2009-01-28 Photocure Asa Product
GB0900461D0 (en) 2009-01-12 2009-02-11 Photocure Asa Photodynamic therapy device
US20100256125A1 (en) * 2009-04-06 2010-10-07 Zila Pharmaceuticals, Inc. Use of improved toluidine blue in photodynamic therapy
EP3078364A1 (en) * 2009-05-26 2016-10-12 The General Hospital Corporation Composition comprising metallic nanoparticles for use in the treatment of acne
EP2440188A1 (en) * 2009-06-11 2012-04-18 Photocure ASA Solid compositions comprising 5-aminolevulinic acid
US20120136055A1 (en) 2009-06-11 2012-05-31 Photocure Asa Semi-solid compositions and pharmaceutical products
KR101133770B1 (ko) * 2009-10-27 2012-04-09 주식회사 엔씨테크론 메틸 5-아미노레불리네이트 염산염의 제조방법과 이를 이용한 여드름 및 피부 개선을 위한 피부 외용 화장료 조성물 및 이의 제조방법
WO2011107478A1 (en) 2010-03-01 2011-09-09 Photocure Asa Cosmetic compositions
EP2394642A1 (en) 2010-06-10 2011-12-14 Universite De Geneve 5-ALA ester formulations and use thereof
WO2011161220A1 (en) 2010-06-23 2011-12-29 Photocure Asa Hyperosmotic preparations comprising 5 -amino levulinic acid or derivative as photosensitizing agent
CA2804337A1 (en) 2010-07-09 2012-01-12 Photocure Asa Dry compositions and devices containing such dry compositions for use in photodynamic therapy or photodynamic diagnosis
JP5522421B2 (ja) 2010-09-14 2014-06-18 学校法人東京農業大学 がん温熱療法の作用増強剤
CN103140457B (zh) * 2010-09-30 2015-05-13 克斯莫石油株式会社 含5-氨基乙酰丙酸的固体肥料及其制造方法
CN103270168A (zh) 2010-12-24 2013-08-28 爱科来株式会社 癌细胞的检测方法
CN102617378B (zh) * 2011-01-26 2016-04-27 上海泺安医药技术有限公司 一种2-(3’-氨基-2’-氧-丙基)丙二酸酯盐及制备
CN102649768B (zh) * 2011-02-25 2016-05-25 上海泺安医药技术有限公司 一种盐酸氨基乙酰丙酸的制备工艺
CN102649769B (zh) * 2011-02-25 2015-12-16 上海泺安医药技术有限公司 一种盐酸氨基乙酰丙酸酯的制备工艺
CN102649767A (zh) * 2011-02-25 2012-08-29 上海泺安医药技术有限公司 一种n-取代氨基乙酰丙酸及其酯制备新工艺
CN102179010B (zh) * 2011-05-27 2013-01-09 吉林大学 脑胶质瘤光动力直接照射治疗装置
CN103635205A (zh) * 2011-07-01 2014-03-12 思佰益药业股份有限公司 使用光增敏剂或5－氨基乙酰丙酸类的光动力学治疗
WO2013053904A1 (en) 2011-10-14 2013-04-18 Photocure Asa Stent
US20140276107A1 (en) 2011-10-14 2014-09-18 Photocure Asa Photodynamic diagnosis
RU2615870C2 (ru) 2011-12-19 2017-04-11 ФотоКьюэр АСА Устройство облучения
WO2013092936A2 (en) 2011-12-20 2013-06-27 Galderma Research & Development Use of 5-aminolevulinic acid and esters, in combination with a vitamin d derivative or analog in photochemotherapy, and their uses in treating acne
US9488664B2 (en) 2012-01-25 2016-11-08 Sbi Pharmaceuticals Co., Ltd. Diagnostic agent for tumor
JP5889398B2 (ja) 2012-04-05 2016-03-22 Ｓｂｉファーマ株式会社 センチネルリンパ節がん転移識別装置
AU2013298525B2 (en) * 2012-08-03 2017-12-14 Photocure Asa Compounds
US20140067024A1 (en) 2012-08-30 2014-03-06 Photocure Asa Dual panel photodynamic therapy lamp
GB201221123D0 (en) 2012-11-23 2013-01-09 Photocure As Device for photodynamic treatment
GB201306369D0 (en) 2013-04-09 2013-05-22 Photocure As Irradiation device
JP6595484B2 (ja) 2013-12-20 2019-10-23 ガルデルマ・リサーチ・アンド・デヴェロップメント 光損傷皮膚のパルス光力学的処置
EP3095464A1 (en) 2015-05-19 2016-11-23 Universite De Geneve 5-ala derivatives and use thereof
GB201522311D0 (en) 2015-12-17 2016-02-03 Photocure Asa Use
SG11201805000RA (en) 2015-12-17 2018-07-30 Photocure Asa Method of photodynamic therapy (pdt) for bladder cancer
GB201522309D0 (en) 2015-12-17 2016-02-03 Photocure Asa Use
GB201522398D0 (en) 2015-12-18 2016-02-03 Photocure As Device for photodynamic therapy
CN112010772A (zh) 2016-01-26 2020-12-01 赵鸣 5-氨基酮戊酸及其衍生物的盐化合物和应用
CA3051727A1 (en) 2017-02-06 2018-08-09 3Skin As Transdermal sunscreen compositions and methods of use thereof
WO2018221291A1 (ja) * 2017-05-31 2018-12-06 Ｓｂｉファーマ株式会社 過活動膀胱の予防剤または治療剤
CN107976508A (zh) * 2017-11-27 2018-05-01 上海百灵医药科技有限公司 一种分析盐酸氨酮戊酸含量和纯度的方法
EP3868372A1 (en) 2020-02-19 2021-08-25 JLP Health GmbH A pharmaceutical combination of an artemisinin compound and a heme synthesis modulator for treating cancer
CN113651708A (zh) * 2021-08-17 2021-11-16 湖南复瑞生物医药技术有限责任公司 一种5-氨基酮戊酸酯化物的制备及后处理方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2411382C3 (de) * 1974-03-09 1979-09-06 C.H. Boehringer Sohn, 6507 Ingelheim 2-Tetrahydrofurfuryl-6,7-benzomorphane, Verfahren zur Herstellung und deren Verwendung
GB2058077B (en) * 1979-06-08 1983-03-09 Szelke M Enkephalin analogues
CA1236029A (en) * 1984-05-14 1988-05-03 Edmund Sandborn Pharmaceutical solutions comprising dimethyl sulfoxide
JPH0745502B2 (ja) * 1987-11-10 1995-05-17 株式会社トクヤマ 新規化合物及びそれを含む組成物
US5079262A (en) * 1989-07-28 1992-01-07 Queen's University At Kingston Method of detection and treatment of malignant and non-malignant lesions utilizing 5-aminolevulinic acid
US5422093A (en) * 1989-07-28 1995-06-06 Queen's University Photochemotherapeutic method using 5-aminolevulinic acid and precursors thereof
US5234940A (en) * 1989-07-28 1993-08-10 Queen's University Photochemotherapeutic method using 5-aminolevulinic acid and precursors thereof
JP2767318B2 (ja) * 1990-04-11 1998-06-18 株式会社コスモ総合研究所 ５―アミノレブリン酸アルキルエステル又はその塩及びその製造方法並びにこれを有効成分とする除草剤
NZ240057A (en) * 1990-10-05 1994-07-26 Univ Kingston Tetrapyrrole derivatives
US5219878A (en) * 1990-10-05 1993-06-15 Queen's University Tetrapyrrole hydroxyalkylamide photochemotherapeutic agents
GB9318841D0 (en) * 1993-09-10 1993-10-27 Res Foundation Of The Norwegia Composition

Also Published As

Publication number Publication date
EP0820432A1 (en) 1998-01-28
NO2005019I2 (no) 2007-04-23
NL300176I2 (nl) 2005-05-02
CA2215069A1 (en) 1996-09-19
PT820432E (pt) 2001-09-28
NO974163D0 (no) 1997-09-09
NO2005019I1 (no) 2005-09-26
CN1137087C (zh) 2004-02-04
JPH11501914A (ja) 1999-02-16
NO318379B1 (no) 2005-03-14
LU90956I2 (fr) 2002-11-13
DE122006000051I1 (de) 2007-01-04
DE69613365T2 (de) 2002-05-02
AU4950096A (en) 1996-10-02
NZ303251A (en) 2000-10-27
WO1996028412A1 (en) 1996-09-19
FR05C0042I2 (no) 2009-10-30
HUP9800460A3 (en) 1998-08-28
JP3955093B2 (ja) 2007-08-08
CZ284897A3 (cs) 1998-03-18
NO2005024I2 (no) 2007-04-23
NL300207I2 (nl) 2005-12-01
CN1178521A (zh) 1998-04-08
EP0820432B1 (en) 2001-06-13
ES2157424T3 (es) 2001-08-16
DE122006000051I2 (de) 2010-07-08
CA2215069C (en) 2006-09-12
CZ291132B6 (cs) 2002-12-11
NL300207I1 (nl) 2005-12-01
NL300176I1 (nl) 2005-05-02
HUP9800460A2 (hu) 1998-07-28
DE69613365D1 (de) 2001-07-19
HU225148B1 (en) 2006-07-28
FR05C0042I1 (no) 2005-02-12
ATE202076T1 (de) 2001-06-15
NO2005024I1 (no) 2005-11-14
AU708076B2 (en) 1999-07-29
KR100444007B1 (ko) 2004-12-03
US6034267A (en) 2000-03-07

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