LU90956I2 - Metvix principe actif méthylaminolevulinique sous forme d'un selde préférence l'hyhrochlorure méthylaminolevulinique - Google Patents

Metvix principe actif méthylaminolevulinique sous forme d'un selde préférence l'hyhrochlorure méthylaminolevulinique

Info

Publication number
LU90956I2
LU90956I2 LU90956C LU90956C LU90956I2 LU 90956 I2 LU90956 I2 LU 90956I2 LU 90956 C LU90956 C LU 90956C LU 90956 C LU90956 C LU 90956C LU 90956 I2 LU90956 I2 LU 90956I2
Authority
LU
Luxembourg
Prior art keywords
methylaminolevulinic
pct
metvix
hydrochloride
active ingredient
Prior art date
Application number
LU90956C
Other languages
English (en)
Original Assignee
Photocure Asa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26306657&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LU90956(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9504948.2A external-priority patent/GB9504948D0/en
Priority claimed from GBGB9525822.4A external-priority patent/GB9525822D0/en
Application filed by Photocure Asa filed Critical Photocure Asa
Publication of LU90956I2 publication Critical patent/LU90956I2/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0061—5-aminolevulinic acid-based PDT: 5-ALA-PDT involving porphyrins or precursors of protoporphyrins generated in vivo from 5-ALA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/145555—Hetero-N

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
LU90956C 1995-03-10 2002-09-13 Metvix principe actif méthylaminolevulinique sous forme d'un selde préférence l'hyhrochlorure méthylaminolevulinique LU90956I2 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9504948.2A GB9504948D0 (en) 1995-03-10 1995-03-10 Compounds
GBGB9525822.4A GB9525822D0 (en) 1995-12-18 1995-12-18 Compounds
PCT/GB1996/000553 WO1996028412A1 (fr) 1995-03-10 1996-03-08 Esters de l'acide 5-aminolevulinique en tant qu'agents photosensibilisants en photochimiotherapie

Publications (1)

Publication Number Publication Date
LU90956I2 true LU90956I2 (fr) 2002-11-13

Family

ID=26306657

Family Applications (1)

Application Number Title Priority Date Filing Date
LU90956C LU90956I2 (fr) 1995-03-10 2002-09-13 Metvix principe actif méthylaminolevulinique sous forme d'un selde préférence l'hyhrochlorure méthylaminolevulinique

Country Status (19)

Country Link
US (1) US6034267A (fr)
EP (1) EP0820432B1 (fr)
JP (1) JP3955093B2 (fr)
KR (1) KR100444007B1 (fr)
CN (1) CN1137087C (fr)
AT (1) ATE202076T1 (fr)
AU (1) AU708076B2 (fr)
CA (1) CA2215069C (fr)
CZ (1) CZ291132B6 (fr)
DE (3) DE69613365T2 (fr)
ES (1) ES2157424T3 (fr)
FR (1) FR05C0042I2 (fr)
HU (1) HU225148B1 (fr)
LU (1) LU90956I2 (fr)
NL (2) NL300176I1 (fr)
NO (3) NO318379B1 (fr)
NZ (1) NZ303251A (fr)
PT (1) PT820432E (fr)
WO (1) WO1996028412A1 (fr)

Families Citing this family (85)

* Cited by examiner, † Cited by third party
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US6492420B2 (en) * 1995-03-10 2002-12-10 Photocure As Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US7530461B2 (en) * 1995-03-10 2009-05-12 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US6992107B1 (en) * 1995-03-10 2006-01-31 Photocure Asa Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy
US5895786A (en) * 1996-05-08 1999-04-20 New York Blood Center, Inc. Method for treating viral infections
GB9700396D0 (en) * 1997-01-10 1997-02-26 Photocure As Photochemotherapeutic compositions
FR2777782B1 (fr) * 1998-04-22 2001-05-18 Alexandre Marti Solution pour la preparation d'une substance pharmaceutique pour le diagnostic et/ou le traitement de lesions tissulaires
US6223071B1 (en) 1998-05-01 2001-04-24 Dusa Pharmaceuticals Inc. Illuminator for photodynamic therapy and diagnosis which produces substantially uniform intensity visible light
DE19852245A1 (de) * 1998-11-12 2000-05-18 Asat Ag Applied Science & Tech 5-Aminolävulinsäure-Nanoemulsion
ATE419384T1 (de) 1999-07-28 2009-01-15 Merck Serono Biodevelopment Durchfluss-mikroreaktor in dem lokale temperaturzyklen auf eine fliessende probe einwirken
JP3970492B2 (ja) * 1999-12-14 2007-09-05 コスモ石油株式会社 ピーリング用組成物
DE10003620A1 (de) * 2000-01-28 2001-08-02 Asat Ag Applied Science & Tech 5-Aminolävulinsäure-Formulierung in nichtwässrigen Lösungsmitteln
NO20002428D0 (no) 2000-05-10 2000-05-10 Radiumhospitalets Forskningsst Hudpreparat
US6454790B1 (en) * 2000-07-21 2002-09-24 Ceramoptec Industries, Inc. Treatment for Barrett's syndrome
GB0018527D0 (en) * 2000-07-27 2000-09-13 Photocure Asa Composition
GB0018528D0 (en) * 2000-07-27 2000-09-13 Photocure Asa Compounds
WO2002013820A1 (fr) * 2000-08-11 2002-02-21 Ceramoptec Industries, Inc. Onguent photosensibilisant
EP1203944B1 (fr) * 2000-11-06 2006-03-01 Hofstetter, Alfons, Prof.Dr.med. Procédé d'identification de cellules turmorales
EP1346059B1 (fr) 2000-11-29 2012-05-23 PCI Biotech AS Internalisation photochimique pour introduire des molecules dans le cytosol
ES2445579T3 (es) * 2000-11-29 2014-03-04 Pci Biotech As Internalización fotoquímica para el suministro de moléculas mediado por virus en el citosol
EP1312353A1 (fr) * 2001-11-16 2003-05-21 Ecole Polytechnique Federale De Lausanne (Epfl) Méthode d'épilation
US6723750B2 (en) 2002-03-15 2004-04-20 Allergan, Inc. Photodynamic therapy for pre-melanomas
US20040073277A1 (en) * 2002-04-05 2004-04-15 Geronemus Roy G. High fluence rate activation of photosensitizers for dermatological applications
DE10301917B4 (de) * 2003-01-17 2007-02-01 Gerhard Saalmann Verwendung von Substanzen der Porphyrinsynthese bei der Phototherapie von Haut- oder Gelenkerkrankungen des Menschen oder von Säugetieren
DE10312659A1 (de) * 2003-03-21 2004-10-07 Universität Regensburg 5-Aminolävulinsäurederivate und ihre Verwendung
US20050209331A1 (en) * 2004-03-22 2005-09-22 Syneron Medical Ltd. Method of treatment of skin
GB0406917D0 (en) 2004-03-26 2004-04-28 Photocure Asa Compounds
BRPI0418784B1 (pt) * 2004-04-28 2014-08-19 Cosmo Oil Co Ltd Composição restauradora de cabelo, e, método não-terapêutico para restaurar cabelo
JP2005350418A (ja) * 2004-06-11 2005-12-22 Shibuya Kogyo Co Ltd 標的細胞の死滅方法と標的細胞を死滅させるための薬剤及び該薬剤の製造装置
JP5034032B2 (ja) * 2004-09-29 2012-09-26 Ｓｂｉファーマ株式会社 腫瘍診断剤
GB0424833D0 (en) * 2004-11-10 2004-12-15 Photocure Asa Method
GB0515550D0 (en) 2005-07-29 2005-09-07 Univ Strathclyde Inactivation of staphylococcus species
US20070225518A1 (en) * 2006-03-22 2007-09-27 Zvi Malik 5-Aminolevulinic acid salts and their use
KR100796450B1 (ko) * 2006-06-29 2008-01-22 전남대학교산학협력단 5-아미노레불린산의 불포화 알킬 에스터 및 약학적으로허용되는 그의 염, 이의 제조방법 및 이의 용도
GB0700580D0 (en) * 2007-01-11 2007-02-21 Photocure Asa Use
JP5098051B2 (ja) 2007-04-05 2012-12-12 Ｓｂｉファーマ株式会社 ミトコンドリア障害脳疾患治療剤及び診断剤
AU2014200004B2 (en) * 2007-12-12 2016-10-27 Photocure Asa Use of 5-aminolevulinic acid and derivatives in a solid form for photodynamic treatment and diagnosis
GB0724279D0 (en) * 2007-12-12 2008-01-23 Photocure Asa Use
AU2008337067A1 (en) * 2007-12-14 2009-06-25 Photoderma Sa Novel compounds useful in therapeutic and cosmetic methods
CN102123587B (zh) 2008-05-13 2014-07-30 克斯莫石油株式会社 草坪草的品质提高剂
CA2722578C (fr) 2008-05-14 2014-02-11 Sbi Alapromo Co., Ltd. Utilisation de l'acide .delta.-aminolevulinique pour traiter la sterilite chez l'homme
AU2009286182B2 (en) 2008-09-01 2013-11-07 Swedish Pharma Ab New 5-aminolevulinic acid prodrugs for use in photodynamic therapy and photodynamic diagnosis
CN101745102B (zh) * 2008-12-16 2013-08-07 上海复旦张江生物医药股份有限公司 5-氨基酮戊酸及其衍生物的组合物及其用途
GB0823472D0 (en) * 2008-12-23 2009-01-28 Photocure Asa Product
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US20100256125A1 (en) * 2009-04-06 2010-10-07 Zila Pharmaceuticals, Inc. Use of improved toluidine blue in photodynamic therapy
CA2974972C (fr) 2009-05-26 2018-12-04 The General Hospital Corporation Procede et appareil pour l'administration dermique d'une substance
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WO2010142457A1 (fr) * 2009-06-11 2010-12-16 Photocure Asa Compositions semi-solides et produits pharmaceutiques
KR101133770B1 (ko) * 2009-10-27 2012-04-09 주식회사 엔씨테크론 메틸 5-아미노레불리네이트 염산염의 제조방법과 이를 이용한 여드름 및 피부 개선을 위한 피부 외용 화장료 조성물 및 이의 제조방법
CA2790827A1 (fr) 2010-03-01 2011-09-09 Photocure Asa Compositions cosmetiques
EP2394642A1 (fr) 2010-06-10 2011-12-14 Universite De Geneve Formulations de 5-ALA ester et leurs utilisations
WO2011161220A1 (fr) 2010-06-23 2011-12-29 Photocure Asa Préparations hyperosmotiques comprenant de l'acide 5-aminolévulinique ou un de ses dérivés en tant qu'agent photosensibilisant
WO2012004399A1 (fr) 2010-07-09 2012-01-12 Photocure Asa Compositions sèches et dispositifs les contenant destinés à être utilisés dans la thérapie photodynamique ou le diagnostic photodynamique
JP5522421B2 (ja) 2010-09-14 2014-06-18 学校法人東京農業大学 がん温熱療法の作用増強剤
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CN102649768B (zh) * 2011-02-25 2016-05-25 上海泺安医药技术有限公司 一种盐酸氨基乙酰丙酸的制备工艺
CN102649769B (zh) * 2011-02-25 2015-12-16 上海泺安医药技术有限公司 一种盐酸氨基乙酰丙酸酯的制备工艺
CN102649767A (zh) * 2011-02-25 2012-08-29 上海泺安医药技术有限公司 一种n-取代氨基乙酰丙酸及其酯制备新工艺
CN102179010B (zh) * 2011-05-27 2013-01-09 吉林大学 脑胶质瘤光动力直接照射治疗装置
CN103635205A (zh) * 2011-07-01 2014-03-12 思佰益药业股份有限公司 使用光增敏剂或5－氨基乙酰丙酸类的光动力学治疗
US20140276107A1 (en) 2011-10-14 2014-09-18 Photocure Asa Photodynamic diagnosis
WO2013053904A1 (fr) 2011-10-14 2013-04-18 Photocure Asa Endoprothèse
KR102057349B1 (ko) 2011-12-19 2019-12-18 포토큐어 에이에스에이 광 조사 기구
WO2013092936A2 (fr) 2011-12-20 2013-06-27 Galderma Research & Development Utilisation d'acide 5-aminolévulinique et d'esters, en combinaison avec un dérivé ou un analogue de la vitamine d en photochimiothérapie, et leurs utilisations dans le traitement de l'acné
JP5836402B2 (ja) * 2012-01-25 2015-12-24 Ｓｂｉファーマ株式会社 腫瘍診断剤
US20150038837A1 (en) 2012-04-05 2015-02-05 Sbi Pharmaceuticals Co., Ltd. Device for determining metastasis of cancer to sentinel lymph node
EP2880012B1 (fr) * 2012-08-03 2021-12-15 Photocure ASA Composés
US20140067024A1 (en) 2012-08-30 2014-03-06 Photocure Asa Dual panel photodynamic therapy lamp
GB201221123D0 (en) 2012-11-23 2013-01-09 Photocure As Device for photodynamic treatment
GB201306369D0 (en) 2013-04-09 2013-05-22 Photocure As Irradiation device
JP6595484B2 (ja) 2013-12-20 2019-10-23 ガルデルマ・リサーチ・アンド・デヴェロップメント 光損傷皮膚のパルス光力学的処置
EP3095464A1 (fr) 2015-05-19 2016-11-23 Universite De Geneve Dérivés de 5-ala et leurs utilisations
GB201522309D0 (en) 2015-12-17 2016-02-03 Photocure Asa Use
AU2016372575B2 (en) 2015-12-17 2022-12-08 Photocure Asa Method of photodynamic therapy (PDT) for bladder cancer
GB201522311D0 (en) 2015-12-17 2016-02-03 Photocure Asa Use
GB201522398D0 (en) 2015-12-18 2016-02-03 Photocure As Device for photodynamic therapy
CN106187793A (zh) 2016-01-26 2016-12-07 赵鸣 5‑氨基酮戊酸及其衍生物的盐化合物和应用
US20200100997A1 (en) 2017-02-06 2020-04-02 3Skin As Sunscreen Composition
US11123320B2 (en) 2017-05-31 2021-09-21 Sbi Pharmaceuticals, Co., Ltd. Prophylactic or therapeutic agent for hyperaciive bladder
CN107976508A (zh) * 2017-11-27 2018-05-01 上海百灵医药科技有限公司 一种分析盐酸氨酮戊酸含量和纯度的方法
EP3868372A1 (fr) 2020-02-19 2021-08-25 JLP Health GmbH Combinaison pharmaceutique d'un composé de l'artémisinine et d'un modulateur de la synthèse de l'hème pour le traitement du cancer
CN113651708A (zh) * 2021-08-17 2021-11-16 湖南复瑞生物医药技术有限责任公司 一种5-氨基酮戊酸酯化物的制备及后处理方法
WO2024184417A1 (fr) 2023-03-07 2024-09-12 Photocure Asa Thérapie contre le cancer de la vessie

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Also Published As

Publication number Publication date
FR05C0042I2 (fr) 2009-10-30
NZ303251A (en) 2000-10-27
NO2005019I1 (no) 2005-09-26
NO318379B1 (no) 2005-03-14
NL300176I2 (nl) 2005-05-02
CN1178521A (zh) 1998-04-08
CA2215069A1 (fr) 1996-09-19
CN1137087C (zh) 2004-02-04
HUP9800460A3 (en) 1998-08-28
NL300176I1 (nl) 2005-05-02
NO2005019I2 (no) 2007-04-23
NO974163L (no) 1997-09-09
NO974163D0 (no) 1997-09-09
AU708076B2 (en) 1999-07-29
FR05C0042I1 (fr) 2005-02-12
EP0820432A1 (fr) 1998-01-28
CZ291132B6 (cs) 2002-12-11
DE122006000051I2 (de) 2010-07-08
WO1996028412A1 (fr) 1996-09-19
NO2005024I2 (no) 2007-04-23
NL300207I1 (nl) 2005-12-01
HU225148B1 (en) 2006-07-28
NO2005024I1 (no) 2005-11-14
US6034267A (en) 2000-03-07
NL300207I2 (nl) 2005-12-01
ES2157424T3 (es) 2001-08-16
ATE202076T1 (de) 2001-06-15
JPH11501914A (ja) 1999-02-16
DE122006000051I1 (de) 2007-01-04
KR100444007B1 (ko) 2004-12-03
CZ284897A3 (cs) 1998-03-18
CA2215069C (fr) 2006-09-12
AU4950096A (en) 1996-10-02
PT820432E (pt) 2001-09-28
EP0820432B1 (fr) 2001-06-13
JP3955093B2 (ja) 2007-08-08
DE69613365D1 (de) 2001-07-19
HUP9800460A2 (hu) 1998-07-28
DE69613365T2 (de) 2002-05-02

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