KR100444007B1 - 광화학치료또는진단에사용하기위한5-아미노레불린산의에스테르 - Google Patents

광화학치료또는진단에사용하기위한5-아미노레불린산의에스테르 Download PDF

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KR100444007B1
KR100444007B1 KR1019970706305A KR19970706305A KR100444007B1 KR 100444007 B1 KR100444007 B1 KR 100444007B1 KR 1019970706305 A KR1019970706305 A KR 1019970706305A KR 19970706305 A KR19970706305 A KR 19970706305A KR 100444007 B1 KR100444007 B1 KR 100444007B1
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ala
fluorescence intensity
fluorescence
compound
skin
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Korean (ko)
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칼 에릭 지에르스크키
요한 모안
퀴안 펭
하랄트 스텐
트론트 왈로에
알프 비오르세트
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포토큐레 에이에스에이
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Priority claimed from GBGB9504948.2A external-priority patent/GB9504948D0/en
Priority claimed from GBGB9525822.4A external-priority patent/GB9525822D0/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0061—5-aminolevulinic acid-based PDT: 5-ALA-PDT involving porphyrins or precursors of protoporphyrins generated in vivo from 5-ALA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/145555—Hetero-N

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1019970706305A 1995-03-10 1996-03-08 광화학치료또는진단에사용하기위한5-아미노레불린산의에스테르 Expired - Lifetime KR100444007B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9504948.2A GB9504948D0 (en) 1995-03-10 1995-03-10 Compounds
GB9504948.2 1995-03-10
GB9525822.4 1995-12-18
GBGB9525822.4A GB9525822D0 (en) 1995-12-18 1995-12-18 Compounds

Publications (1)

Publication Number Publication Date
KR100444007B1 true KR100444007B1 (ko) 2004-12-03

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KR1019970706305A Expired - Lifetime KR100444007B1 (ko) 1995-03-10 1996-03-08 광화학치료또는진단에사용하기위한5-아미노레불린산의에스테르

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US (1) US6034267A (enExample)
EP (1) EP0820432B1 (enExample)
JP (1) JP3955093B2 (enExample)
KR (1) KR100444007B1 (enExample)
CN (1) CN1137087C (enExample)
AT (1) ATE202076T1 (enExample)
AU (1) AU708076B2 (enExample)
CA (1) CA2215069C (enExample)
CZ (1) CZ291132B6 (enExample)
DE (3) DE69613365T2 (enExample)
ES (1) ES2157424T3 (enExample)
FR (1) FR05C0042I2 (enExample)
HU (1) HU225148B1 (enExample)
LU (1) LU90956I2 (enExample)
NL (2) NL300176I2 (enExample)
NO (3) NO318379B1 (enExample)
NZ (1) NZ303251A (enExample)
PT (1) PT820432E (enExample)
WO (1) WO1996028412A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101133770B1 (ko) * 2009-10-27 2012-04-09 주식회사 엔씨테크론 메틸 5-아미노레불리네이트 염산염의 제조방법과 이를 이용한 여드름 및 피부 개선을 위한 피부 외용 화장료 조성물 및 이의 제조방법
KR20150039208A (ko) * 2012-08-03 2015-04-09 포토큐어 에이에스에이 화합물

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US6992107B1 (en) 1995-03-10 2006-01-31 Photocure Asa Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy
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GB9700396D0 (en) 1997-01-10 1997-02-26 Photocure As Photochemotherapeutic compositions
FR2777782B1 (fr) * 1998-04-22 2001-05-18 Alexandre Marti Solution pour la preparation d'une substance pharmaceutique pour le diagnostic et/ou le traitement de lesions tissulaires
US6223071B1 (en) 1998-05-01 2001-04-24 Dusa Pharmaceuticals Inc. Illuminator for photodynamic therapy and diagnosis which produces substantially uniform intensity visible light
DE19852245A1 (de) * 1998-11-12 2000-05-18 Asat Ag Applied Science & Tech 5-Aminolävulinsäure-Nanoemulsion
US7015030B1 (en) 1999-07-28 2006-03-21 Genset S.A. Microfluidic devices and uses thereof in biochemical processes
JP3970492B2 (ja) * 1999-12-14 2007-09-05 コスモ石油株式会社 ピーリング用組成物
DE10003620A1 (de) * 2000-01-28 2001-08-02 Asat Ag Applied Science & Tech 5-Aminolävulinsäure-Formulierung in nichtwässrigen Lösungsmitteln
NO20002428D0 (no) 2000-05-10 2000-05-10 Radiumhospitalets Forskningsst Hudpreparat
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US6723750B2 (en) 2002-03-15 2004-04-20 Allergan, Inc. Photodynamic therapy for pre-melanomas
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DE10301917B4 (de) * 2003-01-17 2007-02-01 Gerhard Saalmann Verwendung von Substanzen der Porphyrinsynthese bei der Phototherapie von Haut- oder Gelenkerkrankungen des Menschen oder von Säugetieren
DE10312659A1 (de) * 2003-03-21 2004-10-07 Universität Regensburg 5-Aminolävulinsäurederivate und ihre Verwendung
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JP5034032B2 (ja) * 2004-09-29 2012-09-26 Ｓｂｉファーマ株式会社 腫瘍診断剤
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KR100796450B1 (ko) 2006-06-29 2008-01-22 전남대학교산학협력단 5-아미노레불린산의 불포화 알킬 에스터 및 약학적으로허용되는 그의 염, 이의 제조방법 및 이의 용도
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Cited By (3)

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Publication number Priority date Publication date Assignee Title
KR101133770B1 (ko) * 2009-10-27 2012-04-09 주식회사 엔씨테크론 메틸 5-아미노레불리네이트 염산염의 제조방법과 이를 이용한 여드름 및 피부 개선을 위한 피부 외용 화장료 조성물 및 이의 제조방법
KR20150039208A (ko) * 2012-08-03 2015-04-09 포토큐어 에이에스에이 화합물
KR102180174B1 (ko) * 2012-08-03 2020-11-19 포토큐어 에이에스에이 화합물

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FR05C0042I2 (enExample) 2009-10-30
EP0820432B1 (en) 2001-06-13
NO974163D0 (no) 1997-09-09
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WO1996028412A1 (en) 1996-09-19
AU4950096A (en) 1996-10-02
ES2157424T3 (es) 2001-08-16
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US6034267A (en) 2000-03-07
CA2215069A1 (en) 1996-09-19
NO318379B1 (no) 2005-03-14
NO2005024I1 (no) 2005-11-14
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JP3955093B2 (ja) 2007-08-08
CZ291132B6 (cs) 2002-12-11
NZ303251A (en) 2000-10-27
CN1137087C (zh) 2004-02-04
NO2005019I2 (no) 2007-04-23
HU225148B1 (en) 2006-07-28
DE69613365T2 (de) 2002-05-02
LU90956I2 (fr) 2002-11-13
AU708076B2 (en) 1999-07-29
NL300207I2 (nl) 2005-12-01
CA2215069C (en) 2006-09-12
PT820432E (pt) 2001-09-28
NL300207I1 (nl) 2005-12-01
JPH11501914A (ja) 1999-02-16
NO2005024I2 (no) 2007-04-23
EP0820432A1 (en) 1998-01-28
DE122006000051I2 (de) 2010-07-08
DE69613365D1 (de) 2001-07-19
HUP9800460A3 (en) 1998-08-28
CZ284897A3 (cs) 1998-03-18
NO974163L (no) 1997-09-09
DE122006000051I1 (de) 2007-01-04

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