AU676041B2 - Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment - Google Patents

Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment Download PDF

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Publication number
AU676041B2
AU676041B2 AU64916/94A AU6491694A AU676041B2 AU 676041 B2 AU676041 B2 AU 676041B2 AU 64916/94 A AU64916/94 A AU 64916/94A AU 6491694 A AU6491694 A AU 6491694A AU 676041 B2 AU676041 B2 AU 676041B2
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AU
Australia
Prior art keywords
radical
group
hydrogen
unsubstituted
tert
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU64916/94A
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English (en)
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AU6491694A (en
Inventor
Ezio Bombardelli
Iwao Ojima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Indena SpA
Research Foundation of the State University of New York
Original Assignee
Indena SpA
Research Foundation of the State University of New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena SpA, Research Foundation of the State University of New York filed Critical Indena SpA
Publication of AU6491694A publication Critical patent/AU6491694A/en
Assigned to INDENA S.P.A., RESEARCH FOUNDATION OF THE STATE UNIVERSITY OF NEW YORK, THE reassignment INDENA S.P.A. Amend patent request/document other than specification (104) Assignors: RESEARCH FOUNDATION OF THE STATE UNIVERSITY OF NEW YORK, THE
Application granted granted Critical
Publication of AU676041B2 publication Critical patent/AU676041B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU64916/94A 1993-03-26 1994-03-24 Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment Ceased AU676041B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/040,189 US5475011A (en) 1993-03-26 1993-03-26 Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment
US040189 1993-03-26
PCT/US1994/003215 WO1994022856A1 (en) 1993-03-26 1994-03-24 Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment

Publications (2)

Publication Number Publication Date
AU6491694A AU6491694A (en) 1994-10-24
AU676041B2 true AU676041B2 (en) 1997-02-27

Family

ID=21909617

Family Applications (1)

Application Number Title Priority Date Filing Date
AU64916/94A Ceased AU676041B2 (en) 1993-03-26 1994-03-24 Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment

Country Status (19)

Country Link
US (3) US5475011A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0690856B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (2) JP3157165B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR100223720B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (1) CN1067682C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE229018T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU676041B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2158147C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CZ (1) CZ288924B6 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE69431833T2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK0690856T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2190440T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HUT73848A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO311722B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PL (2) PL179587B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT690856E (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
RU (1) RU2137764C1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SK (1) SK282317B6 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (1) WO1994022856A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

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Also Published As

Publication number Publication date
ES2190440T3 (es) 2003-08-01
CN1067682C (zh) 2001-06-27
WO1994022856A1 (en) 1994-10-13
JP3157165B2 (ja) 2001-04-16
CA2158147C (en) 1999-10-05
PL180708B1 (pl) 2001-03-30
EP0690856A4 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1996-02-07
EP0690856B1 (en) 2002-12-04
KR100223720B1 (ko) 1999-10-15
JPH08508497A (ja) 1996-09-10
CZ248095A3 (en) 1996-03-13
JP3145993B2 (ja) 2001-03-12
JPH11322737A (ja) 1999-11-24
CN1123547A (zh) 1996-05-29
US5705508A (en) 1998-01-06
NO953796L (no) 1995-11-15
KR960701045A (ko) 1996-02-24
NO311722B1 (no) 2002-01-14
CA2158147A1 (en) 1994-10-13
DE69431833D1 (de) 2003-01-16
PL310827A1 (en) 1996-01-08
SK282317B6 (sk) 2002-01-07
NO953796D0 (no) 1995-09-25
DE69431833T2 (de) 2003-11-06
AU6491694A (en) 1994-10-24
EP0690856A1 (en) 1996-01-10
DK0690856T3 (da) 2003-03-31
PT690856E (pt) 2003-04-30
US5599820A (en) 1997-02-04
US5475011A (en) 1995-12-12
CZ288924B6 (cs) 2001-09-12
HU9502642D0 (en) 1995-11-28
PL179587B1 (pl) 2000-09-29
RU2137764C1 (ru) 1999-09-20
HUT73848A (en) 1996-09-30
SK118395A3 (en) 1996-06-05
ATE229018T1 (de) 2002-12-15

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