AU6400098A - Fermentative production of valuable compounds on an industrial scale using chemically defined media - Google Patents

Fermentative production of valuable compounds on an industrial scale using chemically defined media

Info

Publication number
AU6400098A
AU6400098A AU64000/98A AU6400098A AU6400098A AU 6400098 A AU6400098 A AU 6400098A AU 64000/98 A AU64000/98 A AU 64000/98A AU 6400098 A AU6400098 A AU 6400098A AU 6400098 A AU6400098 A AU 6400098A
Authority
AU
Australia
Prior art keywords
industrial scale
chemically defined
fermentative production
defined media
valuable compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU64000/98A
Other languages
English (en)
Inventor
Wilhelmus Theodorus Antonius Maria De Laat
Bertus Pieter Koekman
Johannes Cornelis Gerardus Preusting
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM Delft BV
Original Assignee
Gist Brocades BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gist Brocades BV filed Critical Gist Brocades BV
Publication of AU6400098A publication Critical patent/AU6400098A/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405Glucanases
    • C12N9/2408Glucanases acting on alpha -1,4-glucosidic bonds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/04Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using bacteria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90Isomerases (5.)
    • C12N9/92Glucose isomerase (5.3.1.5; 5.3.1.9; 5.3.1.18)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02Oxygen as only ring hetero atoms
    • C12P17/06Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/188Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/60Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P23/00Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P37/00Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436Fatty acid esters
    • C12P7/6445Glycerides
    • C12P7/6472Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Mycology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
AU64000/98A 1997-02-20 1998-02-20 Fermentative production of valuable compounds on an industrial scale using chemically defined media Abandoned AU6400098A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97200494 1997-02-20
PCT/EP1998/001122 WO1998037179A2 (en) 1997-02-20 1998-02-20 Fermentative production of valuable compounds on an industrial scale using chemically defined media

Publications (1)

Publication Number Publication Date
AU6400098A true AU6400098A (en) 1998-09-09

Family

ID=8228032

Family Applications (1)

Application Number Title Priority Date Filing Date
AU64000/98A Abandoned AU6400098A (en) 1997-02-20 1998-02-20 Fermentative production of valuable compounds on an industrial scale using chemically defined media

Country Status (17)

Country Link
US (3) US20020039758A1 (https=)
EP (4) EP2256211A3 (https=)
JP (4) JP4217277B2 (https=)
KR (1) KR100576576B1 (https=)
CN (2) CN1127571C (https=)
AT (1) ATE327340T1 (https=)
AU (1) AU6400098A (https=)
BR (1) BR9807362A (https=)
CZ (1) CZ299290B6 (https=)
DE (1) DE69834630T2 (https=)
ES (1) ES2262228T3 (https=)
ID (1) ID23995A (https=)
PL (1) PL335227A1 (https=)
PT (1) PT970236E (https=)
RU (1) RU99120113A (https=)
SI (1) SI0970236T1 (https=)
WO (1) WO1998037179A2 (https=)

Families Citing this family (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5340742A (en) 1988-09-07 1994-08-23 Omegatech Inc. Process for growing thraustochytrium and schizochytrium using non-chloride salts to produce a microfloral biomass having omega-3-highly unsaturated fatty acids
CZ299290B6 (cs) * 1997-02-20 2008-06-11 Dsm Ip Assets B.V. Zpusob výroby beta-laktamové slouceniny, zpusob prípravy a/nebo zlepšení vláknitého mikrobiálního kmene a použití chemicky definovaného fermentacníhomédia
US6004784A (en) * 1998-09-14 1999-12-21 General Electric Co. Fermentation medium and method for producing α, ω -alkanedicarboxylic acids
US6440708B1 (en) 1998-09-29 2002-08-27 Dsm N.V. Fermentation of clavulanic acid at a controlled level of ammonia
EP2960325B1 (en) * 2000-01-28 2017-09-27 DSM IP Assets B.V. Enhanced production of lipids containing polyenoic fatty acids by high density cultures of eukaryotic microbes in fermentors
DE10106493B4 (de) * 2001-02-13 2010-11-04 Plasmidfactory Gmbh & Co. Kg Verfahren zur Herstellung von Nukleinsäuren
ATE420161T1 (de) 2002-07-01 2009-01-15 Novozymes As Monopropylenglykol als fermentationszusatz
KR100454508B1 (ko) * 2002-07-05 2004-11-03 허명준 소취기능과 다제내성균에 대한 멸균력을 갖는 자연기능수및 그의 제조방법
US6955892B2 (en) * 2002-11-12 2005-10-18 Akzo Nobel N.V. Feeding processes for fermentation
DE10317877A1 (de) * 2003-04-17 2004-11-18 Consortium für elektrochemische Industrie GmbH Verfahren zur Herstellung von Sporidiobolus ruineniae Stämmen mit verbesserter Coenzym Q10-Produktion
KR20060061295A (ko) 2003-05-28 2006-06-07 디에스엠 아이피 어셋츠 비.브이. 세펨 화합물
AU2005212237B2 (en) 2004-02-04 2009-06-11 Merck Sharp & Dohme Llc Process for large scale production of plasmid DNA by E. coli fermentation
US20080050779A1 (en) * 2004-06-16 2008-02-28 Aurelia Defachelles Fermentation Process Using Faba Beans as Nitrogen Source
CN103589650A (zh) 2005-03-18 2014-02-19 米克罗比亚公司 产油酵母和真菌中类胡萝卜素的产生
EP1861505A1 (en) * 2005-03-24 2007-12-05 DSMIP Assets B.V. Process for microbial production of a valuable compound
US7990102B2 (en) * 2006-02-09 2011-08-02 Karl Frederick Scheucher Cordless power supply
KR100839874B1 (ko) * 2006-07-07 2008-06-19 자연과생명기술(주) 분말 발효제 제조 방법
WO2008042338A2 (en) 2006-09-28 2008-04-10 Microbia, Inc. Production of carotenoids in oleaginous yeast and fungi
EP2592149A1 (en) 2007-03-21 2013-05-15 DSM IP Assets B.V. Improved method for homologous recombination
US20130189722A1 (en) * 2007-09-05 2013-07-25 Joshua Trueheart Isolation of pellet-forming microorganisms
EP2310487A2 (en) 2008-08-05 2011-04-20 DSM IP Assets B.V. Adipoyl-7-adca producing strains
EP2213723A1 (en) 2009-01-30 2010-08-04 Novozymes A/S Isomaltose for fungus fermentation
CN102414317B (zh) 2009-02-27 2014-11-05 诺维信公司 具有减少的金属肽酶表达、适于重组多肽产生的突变细胞
BR112012000078A2 (pt) 2009-07-03 2017-03-01 Dsm Ip Assets Bv cepas de talaromyces e composições de enzima.
IN2012DN03186A (https=) 2009-11-04 2015-09-25 Dsm Ip Assets Bv
WO2011120882A1 (en) 2010-03-30 2011-10-06 Novozymes A/S Crystal metabolite recovery
KR101013456B1 (ko) * 2010-11-24 2011-02-14 주식회사 그린바이오텍 심플리실리움 라멜리콜라 bcp 균주 배양용 배지 조성물 및 이의 배양방법
WO2012088276A2 (en) * 2010-12-21 2012-06-28 J3H, Inc Phospholipid production and composition manipulation through media manipulation
CA2823270A1 (en) 2011-01-31 2012-08-09 Novozymes A/S Use of browned glucose as a feed substrate
EP2683732B1 (en) 2011-03-11 2016-08-24 DSM IP Assets B.V. Vector-host system
WO2012150968A1 (en) * 2011-05-02 2012-11-08 Renewuel Llc System and method of co-cultivating microalgae with fungus
JP2014521356A (ja) 2011-08-12 2014-08-28 ノボザイムス アクティーゼルスカブ マンガン添加による培養液粘度の低減
US20150197760A1 (en) 2012-06-19 2015-07-16 Dsm Ip Assets B.V. Promoters for expressing a gene in a cell
EP2870256A1 (en) 2012-07-06 2015-05-13 Novozymes A/S Inactivation of a production strain using a fatty acid
WO2014030774A1 (ja) 2012-08-24 2014-02-27 国立大学法人山口大学 酵母用培地
EP2914611B1 (en) 2012-11-01 2018-08-29 Novozymes A/S Method for removal of dna
PL3686280T3 (pl) 2013-02-04 2022-09-19 Dsm Ip Assets B.V. Polipeptyd degradujący węglowodany i jego zastosowania
US9943545B2 (en) * 2013-03-15 2018-04-17 Fate Therapeutics, Inc. Stem cell culture media and methods of enhancing cell survival
WO2014202624A2 (en) 2013-06-19 2014-12-24 Dsm Ip Assets B.V. Rasamsonia gene and use thereof
WO2014202622A2 (en) 2013-06-19 2014-12-24 Dsm Ip Assets B.V. Rasamsonia gene and use thereof
WO2014202620A2 (en) 2013-06-19 2014-12-24 Dsm Ip Assets B.V. Rasamsonia gene and use thereof
WO2014202621A1 (en) 2013-06-20 2014-12-24 Dsm Ip Assets B.V. Carbohydrate degrading polypeptide and uses thereof
EP2826384A1 (de) 2013-07-16 2015-01-21 Evonik Industries AG Verfahren zur Trocknung von Biomasse
JP6393898B2 (ja) * 2014-08-03 2018-09-26 国立大学法人 奈良先端科学技術大学院大学 酵母の培養方法
CA2958439C (en) 2014-10-02 2022-09-20 Evonik Industries Ag Feedstuff of high abrasion resistance and good stability in water, containing pufas
ES2873094T3 (es) 2014-10-02 2021-11-03 Evonik Operations Gmbh Procedimiento para la producción de un pienso que contiene PUFAs mediante extrusión de una biomasa que contiene PUFAs de tipo Labyrinthulomycetes
FI3200604T4 (fi) 2014-10-02 2025-07-29 Evonik Operations Gmbh Menetelmä rehun valmistamiseksi
ES2870093T3 (es) 2014-10-02 2021-10-26 Evonik Operations Gmbh Biomasa que contiene PUFA con estabilidad celular elevada y su empleo para la producción de piensos
CA3005292A1 (en) 2015-12-09 2017-06-15 Basf Se Method of purifying a protein from fermentation solids under desorbing conditions
CN105505829A (zh) * 2016-01-20 2016-04-20 黑龙江省中医药科学院 发酵类中药优势菌群选择性培养基及其制备方法和发酵类中药优势菌的筛选方法
US10945439B2 (en) 2016-04-12 2021-03-16 Wim De Laat Consultancy B.V. Pseudomonas strains and consortia thereof for use in protection against plant diseases
EP3484996B1 (en) 2016-07-14 2020-09-09 Basf Se Fermentation medium comprising chelating agent
JP2018023356A (ja) * 2016-08-04 2018-02-15 三洋化成工業株式会社 有用物質の生産方法
US11707078B2 (en) 2016-08-11 2023-07-25 The Protein Brewery B.V. Single cell protein from thermophilic fungi
BR112020002605A2 (pt) 2017-08-07 2020-07-28 Novozymes A/S uso de controle de fca com base em ph
CN110452945B (zh) * 2018-05-07 2023-06-23 华东理工大学 利用红色糖多孢菌发酵生产红霉素的方法
WO2020169564A1 (en) 2019-02-20 2020-08-27 Basf Se Industrial fermentation process for bacillus using defined medium and trace element feed
CN114096676A (zh) 2019-02-20 2022-02-25 巴斯夫欧洲公司 用确定成分培养基和镁补料的芽孢杆菌工业发酵工艺
US12146171B2 (en) 2019-06-13 2024-11-19 Basf Se Method of recovering a protein from fermentation broth using a divalent cation
CN110283854B (zh) * 2019-08-08 2021-07-16 内蒙古金达威药业有限公司 一种发酵培养基及其应用和利用三孢布拉霉菌发酵制备番茄红素的方法
EP4077699A1 (en) 2019-12-19 2022-10-26 Basf Se Increasing space-time-yield, carbon-conversion-efficiency and carbon substrate flexibility in the production of fine chemicals
US20230041211A1 (en) 2019-12-20 2023-02-09 Basf Se Decreasing toxicity of terpenes and increasing the production potential in micro-organisms
KR102264895B1 (ko) * 2019-12-27 2021-06-15 명지대학교 산학협력단 메탄올을 소비하는 Aspergillus 균주를 이용한 유기산 생산 공정
US20230212634A1 (en) 2020-01-14 2023-07-06 The Protein Brewery B.V. Expression of Ovalbumin and its Natural Variants
US12157881B2 (en) * 2020-01-23 2024-12-03 The Protein Brewery B.V. Use of a defoamer for maintaining dispersed morphology in submerged fungal fermentation
WO2021176033A1 (en) 2020-03-06 2021-09-10 The Protein Brewery B.V. Improved single-cell protein production using antioxidants
AU2021230099A1 (en) 2020-03-06 2022-09-22 The Protein Brewery B.V. Pasteurisation of microbial biomass suitable for food applications
CN111548944B (zh) * 2020-06-05 2022-06-14 福建省农业科学院植物保护研究所 一种促进莱氏绿僵菌产孢的固体发酵培养基及其制备方法和应用
CA3181847A1 (en) 2020-06-23 2021-12-30 Elisa LEUNE Novel food
US20230323329A1 (en) 2020-09-04 2023-10-12 Basf Se Method for removing antifoaming agents from a fermentation broth
MX2023003276A (es) 2020-09-22 2023-05-03 Basf Se Método para recuperar una proteína de un caldo de fermentación que comprende un alto grado de células lisadas.
WO2023118565A1 (en) 2021-12-23 2023-06-29 Novozymes A/S Reduction of residual dna in microbial fermentation products
WO2023242273A1 (en) 2022-06-14 2023-12-21 Newmilkbuzz B.V. Expression of milk caseins in filamentous fungi
EP4349993A1 (en) 2022-10-06 2024-04-10 SecondCircle ApS Optimised fermentation of anaerobic bacteria
EP4623075A1 (en) 2022-11-22 2025-10-01 NewMilkBuzz B.V Improved casein secretion by non-mammalian host cells
WO2024133849A1 (en) 2022-12-22 2024-06-27 The Protein Brewery B.V. Ovalbumin fermentation
WO2024256611A1 (en) 2023-06-14 2024-12-19 Newmilkbuzz B.V Production of an alphas1-casein in a yeast or a filamentous fungus host
WO2025109136A1 (en) 2023-11-22 2025-05-30 Newmilkbuzz B.V Expression of milk caseins in non-mammalian cells
WO2025233389A1 (en) 2024-05-09 2025-11-13 Novozymes A/S Stabilized liquid deamidase compositions

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3205150A (en) * 1961-11-27 1965-09-07 Ca Nat Research Council Hydroxy fatty acid production
US3700558A (en) * 1967-11-20 1972-10-24 Lepetit Spa Production of l-tryptophan by fermentation
NZ177159A (en) * 1974-04-20 1978-03-06 Beecham Group Ltd Clavulanic acid, salts, esters and preparation thereof from streptomyces clavuligerus: pharmaceutical compositions
IE41489B1 (en) * 1974-07-30 1980-01-16 Ici Ltd Production of glucose isomerase
US4164445A (en) * 1975-03-27 1979-08-14 E. R. Squibb & Sons, Inc. Ethanol as the major source of carbon and energy in penicillin production
US4077842A (en) * 1976-03-19 1978-03-07 Cory Robert Paul Stabilized glucose isomerase enzyme concentrate
IL60219A (en) * 1979-06-15 1985-05-31 Merck & Co Inc Hypocholesteremic fermentation products of the hmg-coa reductase inhibitor type,their preparation and pharmaceutical compositions containing them
US4231938A (en) * 1979-06-15 1980-11-04 Merck & Co., Inc. Hypocholesteremic fermentation products and process of preparation
US4348481A (en) * 1979-11-29 1982-09-07 Institute Po Microbiologia Method of obtaining glucose isomerase
US4374929A (en) * 1980-07-14 1983-02-22 Standard Oil Company (Indiana) Production of xanthan gum from a chemically defined medium introduction
JPS59205979A (ja) * 1983-05-11 1984-11-21 Agency Of Ind Science & Technol 微生物菌体の製造方法
MX7417E (es) * 1984-10-27 1988-10-14 Antibioticos Sa Metodo para la preparacion de acido clavulanico y sus derivados
JP2746371B2 (ja) * 1987-12-21 1998-05-06 サントリー株式会社 ビスホモ−γ−リノレン酸及びこれを含有する脂質の製造方法
US5376536A (en) * 1988-07-15 1994-12-27 Gist-Brocades, N.V. Glucose isomerase enzymes and their use
US5290690A (en) * 1988-07-15 1994-03-01 Plant Genetic Systems Methods and means for controlling the stability of proteins
EP0351029B1 (en) * 1988-07-15 2002-03-06 Genencor International, Inc. Novel glucose isomerase enzymes and their use
CH680448A5 (https=) * 1990-01-17 1992-08-31 Nestle Sa
US5658767A (en) * 1991-01-24 1997-08-19 Martek Corporation Arachidonic acid and methods for the production and use thereof
US5318896A (en) * 1991-09-11 1994-06-07 Merck & Co., Inc. Recombinant expandase bioprocess for preparing 7-aminodesacetoxy cephalosporanic acid (7-ADCA)
NZ245713A (en) * 1992-02-10 1994-12-22 Novopharm Ltd Production of the antibiotic lovastatin from genetically engineered aspergillus strains
GB9220670D0 (en) * 1992-09-30 1992-11-11 Unilever Plc Cosmetic composition
FR2700552B1 (fr) * 1993-01-19 1995-04-21 Pernod Ricard Mutants de Phaffia rhodozyma, procédé de production de beta-carotène et utilisation de biomasse riche en beta-carotène.
BR9407108A (pt) * 1993-07-30 1996-08-27 Gist Brocades Nv Processo para a preparação e recuperação de ácido 7-amino desacetoxi cefalosporânico (7-adca) vetor de ADN recombinante e célula hospedeira transformada com um vetor definido
JP2677949B2 (ja) * 1993-08-26 1997-11-17 常盤薬品工業株式会社 アラキドン酸含有健康食品
US5494808A (en) * 1994-09-15 1996-02-27 Merck & Co., Inc. Defined medium OMPC fermentation process
US5583019A (en) * 1995-01-24 1996-12-10 Omegatech Inc. Method for production of arachidonic acid
WO1996038051A1 (en) * 1995-05-30 1996-12-05 Suntory Limited Fowl eggs with high content of highly unsaturated fatty acids, process for producing the same, and use thereof
US5731165A (en) * 1995-06-02 1998-03-24 Gist-Brocades, B.V. Process for the production of 7-ADCA via expandase activity on penicillin G
SI9500238A (en) * 1995-07-27 1997-02-28 Krka Tovarna Zdravil Procedure for the production of lovastatin
US5989877A (en) * 1995-08-03 1999-11-23 Gist-Brocades B.V. Selective process for the deacylation of acylated compounds
US6255505B1 (en) * 1996-03-28 2001-07-03 Gist-Brocades, B.V. Microbial polyunsaturated fatty acid containing oil from pasteurised biomass
US20030143659A1 (en) * 1996-03-28 2003-07-31 Hendrik Louis Bijl Process for the preparation of a granular microbial biomass and isolation of a compound thereform
CZ299290B6 (cs) * 1997-02-20 2008-06-11 Dsm Ip Assets B.V. Zpusob výroby beta-laktamové slouceniny, zpusob prípravy a/nebo zlepšení vláknitého mikrobiálního kmene a použití chemicky definovaného fermentacníhomédia
WO1998039468A1 (en) * 1997-03-04 1998-09-11 Suntory Limited Process for preparing highly unsaturated fatty acid and lipid containing highly unsaturated fatty acid

Also Published As

Publication number Publication date
EP0970236A2 (en) 2000-01-12
SI0970236T1 (sl) 2006-10-31
JP2008200053A (ja) 2008-09-04
PT970236E (pt) 2006-08-31
CN1495259A (zh) 2004-05-12
JP4469401B2 (ja) 2010-05-26
CZ299290B6 (cs) 2008-06-11
US20140342396A1 (en) 2014-11-20
EP0970236B1 (en) 2006-05-24
DE69834630T2 (de) 2007-04-19
ATE327340T1 (de) 2006-06-15
US20070092955A1 (en) 2007-04-26
JP4217277B2 (ja) 2009-01-28
EP1690945A2 (en) 2006-08-16
CN1127571C (zh) 2003-11-12
JP2001512970A (ja) 2001-08-28
JP2009195254A (ja) 2009-09-03
ES2262228T3 (es) 2006-11-16
EP1690945A3 (en) 2009-06-03
EP2256211A3 (en) 2011-02-16
CZ295499A3 (cs) 2000-04-12
CN1248294A (zh) 2000-03-22
ID23995A (id) 2000-06-14
EP2345734A2 (en) 2011-07-20
WO1998037179A2 (en) 1998-08-27
PL335227A1 (en) 2000-04-10
EP2256211A2 (en) 2010-12-01
CN100351386C (zh) 2007-11-28
KR100576576B1 (ko) 2006-05-04
BR9807362A (pt) 2000-04-18
KR20000075487A (ko) 2000-12-15
DE69834630D1 (de) 2006-06-29
US20020039758A1 (en) 2002-04-04
JP2014087365A (ja) 2014-05-15
RU99120113A (ru) 2002-12-27
EP2345734A3 (en) 2012-03-21
WO1998037179A3 (en) 1999-01-14

Similar Documents

Publication Publication Date Title
AU6400098A (en) Fermentative production of valuable compounds on an industrial scale using chemically defined media
WO2003012058A3 (en) Media and methods for cultivation of microorganisms
CA2269088A1 (en) Method for the production of 1,3-propanediol by recombinant organisms
WO2001048237A3 (de) Verfahren zur schnellen bestimmung von mikrobieller dns/rns, kit dafür und verwendung des verfahrens
WO2002018617A3 (en) Carotenoid production by recombinant, c1-metabolizing methanothropic bacteria
WO2008026104A3 (en) Array for rapid detection of a microorganism
CA2386539A1 (en) Method for production of l-cysteine or l-cysteine derivatives by fermentation
CA2333966A1 (en) Media for culturing animal cells and process for producing protein by using the same
SE8904262D0 (sv) Microbial processfor the production of immunosupp ressive antibiotics
WO2000012725A3 (en) Transgenic amorpha-4,11-diene synthesis
CA2291929A1 (en) Novel microorganisms, microbial symbionts, their culture methods, and methods for treating manganese-containing water using them
CA2173115A1 (en) Genes for butyrobetaine/crotonobetaine-l-carnitine metabolism and their use for the microbiological production of l-carnitine
AU6230596A (en) Animal feed
WO1994020604A3 (en) Agricultural-chemical-producing endosymbiotic microorganisms and method of preparing and using same
WO2004106557A3 (en) Thiamin production by fermentation
WO2003070873A3 (de) Kultivierungsverfahren für mikroorganismen und bioreaktor
WO2001074850A1 (en) Antibiotics tripropeptins and process for producing the same
BR0003302A (pt) Produção microbiana de levodiona
EP1405913A3 (en) Process for improving the production of 5R clavams
WO2005004606A3 (en) Pyridinylanilides
AU3289995A (en) Variety classification method for barley or malt using gene diagnosis and the primer used therefor
WO2005079276A3 (en) Selective growth medium for listeria spp
BRPI9816369C1 (pt) processo para produção de ácido araquidônico
WO2004092400A3 (fr) Milieu de détection et/ou d'identification de micro-organismes
AU2001278551A1 (en) Method for detecting micro-organisms